Nox2 and Nox4 mediate tumour necrosis factor-α-induced ventricular remodelling in mice

Journal of Cellular and Molecular Medicine

Volumn 15, Issue 12, 2011, Pages 2601-2613

  Moe, K T ^a   Yin, N O ^a   Naylynn, T M ^a   Khairunnisa, K ^a   Wutyi, M A ^a   Gu, Y ^a   Atan, M S M ^a   Wong, M C ^a   Koh, T H ^a   Wong, P ^a  

^a DEPARTMENT OF CARDIOLOGY   (Singapore)

Author keywords

NADPH oxidase; Nox2; Nox4; Tumour necrosis factor ; Ventricular remodelling

Indexed keywords

ANTIOXIDANT; CYBB PROTEIN, MOUSE; CYTOKINE; INTERLEUKIN 1BETA; INTERLEUKIN 6; MEMBRANE PROTEIN; MESSENGER RNA; NOX4 PROTEIN, MOUSE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL; ARTICLE; CELL CULTURE; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; ENZYME IMMUNOASSAY; GENETICS; HEART MUSCLE CELL; HEART VENTRICLE REMODELING; HUMAN; MALE; METABOLISM; MOUSE; OXIDATIVE STRESS; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; ANTIOXIDANTS; BLOTTING, WESTERN; CELLS, CULTURED; CYTOKINES; HUMANS; IMMUNOENZYME TECHNIQUES; INTERLEUKIN-1BETA; INTERLEUKIN-6; MALE; MEMBRANE GLYCOPROTEINS; MICE; MYOCYTES, CARDIAC; NADPH OXIDASE; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; TUMOR NECROSIS FACTOR-ALPHA; VENTRICULAR REMODELING;

EID: 82455220308     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1582-4934.2011.01261.x     Document Type: Article

References (43)

1. Cohn JN, Ferrari R, Sharpe N. Cardiac remodeling-concepts and clinical implications: a consensus paper from an international forum on cardiac remodeling. Behalf of an International Forum on Cardiac Remodeling. J Am Coll Cardiol. 2000; 35: 569-82.
2. Paul S. Ventricular remodeling. Crit Care Nurs Clin North Am. 2003; 15: 407-11.
3. Torre-Amione G, Kapadia S, Benedict C, et al. Proinflammatory cytokine levels in patients with depressed left ventricular ejection fraction: a report from the Studies of Left Ventricular Dysfunction (SOLVD). J Am Coll Cardiol. 1996; 27: 1201-6.
4. Torre-Amione G, Kapadia S, Lee J, et al. Tumor necrosis factor-alpha and tumor necrosis factor receptors in the failing human heart. Circulation. 1996; 93: 704-11.
5. Bozkurt B, Kribbs SB, Clubb FJ Jr, et al. Pathophysiologically relevant concentrations of tumor necrosis factor-alpha promote progressive left ventricular dysfunction and remodeling in rats. Circulation. 1998; 97: 1382-91.
6. Kubota T, McTiernan CF, Frye CS, et al. Cardiac-specific overexpression of tumor necrosis factor-alpha causes lethal myocarditis in transgenic mice. J Card Fail. 1997; 3: 117-24.
7. Cave A, Grieve D, Johar S, et al. NADPH oxidase-derived reactive oxygen species in cardiac pathophysiology. Philos Trans R Soc Lond B Biol Sci. 2005; 360: 2327-34.
8. Lyle AN, Griendling KK. Modulation of vascular smooth muscle signaling by reactive oxygen species. Physiology (Bethesda). 2006; 21: 269-80.
9. Moe KT, Aulia S, Jiang F, et al. Differential upregulation of Nox homologues of NADPH oxidase by tumor necrosis factor-alpha in human aortic smooth muscle and embryonic kidney cells. J Cell Mol Med. 2006; 10: 231-9.
10. Higashi M, Shimokawa H, Hattori T, et al. Long-term inhibition of Rho-kinase suppresses angiotensin II-induced cardiovascular hypertrophy in ratsin vivo: effect on endothelial NAD(P)H oxidase system. Circ Res. 2003; 93: 767-75.
11. Sturrock A, Cahill B, Norman K, et al. Transforming growth factor-beta1 induces Nox4 NAD(P)H oxidase and reactive oxygen species-dependent proliferation in human pulmonary artery smooth muscle cells.Am J Physiol Lung Cell Mol Physiol. 2006; 290: L661-73.
12. Bendall JK, Cave AC, Heymes C, et al. Pivotal role of a gp91(phox)-containing NADPH oxidase in angiotensin II-induced cardiac hypertrophy in mice. Circulation. 2002; 105: 293-6.
13. Byrne JA, Grieve DJ, Bendall JK, et al. Contrasting roles of NADPH oxidase isoforms in pressure-overloadversusangiotensin II-induced cardiac hypertrophy. Circ Res. 2003; 93: 802-5.
14. Zhao W, Zhao D, Yan R, et al. Cardiac oxidative stress and remodeling following infarction: role of NADPH oxidase. Cardiovasc Pathol. 2009; 18: 156-66.
15. Zhou Z, Kang X, Jiang Y, et al. Preservation of hepatocyte nuclear factor-4alpha is associated with zinc protection against TNF-alpha hepatotoxicity in mice. Exp Biol Med. 2007; 232: 622-8.
16. Weytjens C, Cosyns B, D'Hooge J, et al. Doppler myocardial imaging in adult male rats: reference values and reproducibility of velocity and deformation parameters. Eur J Echocardiogr. 2006; 7: 411-7.
17. -/- mice show defective angiogenesis associated with increased oxidative stress in response to tissue ischemia. FASEB J. 2006; 20: 970-2.
18. Sun M, Chen M, Dawood F, et al. Tumor necrosis factor-alpha mediates cardiac remodeling and ventricular dysfunction after pressure overload state. Circulation. 2007; 115: 1398-407.
19. Maity P, Bindu S, Dey S, et al. Indomethacin, a non-steroidal anti-inflammatory drug, develops gastropathy by inducing reactive oxygen species-mediated mitochondrial pathology and associated apoptosis in gastric mucosa: a novel role of mitochondrial aconitase oxidation. J Biol Chem. 2009; 284: 3058-68.
20. Looi YH, Grieve DJ, Siva A, et al. Involvement of Nox2 NADPH oxidase in adverse cardiac remodeling after myocardial infarction. Hypertension. 2008; 51: 319-25.
21. Odaka C. Localization of mesenchymal cells in adult mouse thymus: their abnormal distribution in mice with disorganization of thymic medullary epithelium. J Histochem Cytochem. 2009; 57: 373-82.
22. Melgar S, Karlsson A, Michaelsson E. Acute colitis induced by dextran sulfate sodium progresses to chronicity in C57BL/6 but not in BALB/c mice: correlation between symptoms and inflammation.Am J Physiol Gastrointest Liver Physiol. 2005; 288: G1328-38.
23. Luyten CR, van Overveld FJ, De Backer LA, et al. Antioxidant defence during cardiopulmonary bypass surgery. Eur J Cardiothorac Surg. 2005; 27: 611-6.
24. Sherer TB, Betarbet R, Stout AK, et al. Anin vitromodel of Parkinson's disease: linking mitochondrial impairment to altered alpha-synuclein metabolism and oxidative damage. J Neurosci. 2002; 22: 7006-15.
25. Turan N, Csonka C, Csont T, et al. The role of peroxynitrite in chemical preconditioning with 3-nitropropionic acid in rat hearts. Cardiovasc Res. 2006; 70: 384-90.
26. Mukhopadhyay P, Rajesh M, Batkai S, et al. Role of superoxide, nitric oxide, and peroxynitrite in doxorubicin-induced cell deathin vivoandin vitro.Am J Physiol Heart Circ Physiol. 2009; 296: H1466-83.
27. Gertzberg N, Neumann P, Rizzo V, et al. NAD(P)H oxidase mediates the endothelial barrier dysfunction induced by TNF-alpha.Am J Physiol Lung Cell Mol Physiol. 2004; 286: L37-48.
28. Moe TK, Ziliang J, Barathi A, et al. Differential expression of glyceraldehyde-3-phosphate dehydrogenase (GAPDH), beta actin and hypoxanthine phosphoribosyltransferase (HPRT) in postnatal rabbit sclera. Curr Eye Res. 2001; 23: 44-50.
29. Sun M, Dawood F, Wen WH, et al. Excessive tumor necrosis factor activation after infarction contributes to susceptibility of myocardial rupture and left ventricular dysfunction. Circulation. 2004; 110: 3221-8.
30. Levine B, Kalman J, Mayer L, et al. Elevated circulating levels of tumor necrosis factor in severe chronic heart failure. N Engl J Med. 1990; 323: 236-41.
31. Kuntz ID, Chen K, Sharp KA, et al. The maximal affinity of ligands. Proc Natl Acad Sci USA. 1999; 96: 9997-10002.
32. Meldrum DR. Tumor necrosis factor in the heart.Am J Physiol. 1998; 274: R577-95.
33. Oral H, Dorn GW 2nd, Mann DL. Sphingosine mediates the immediate negative inotropic effects of tumor necrosis factor-alpha in the adult mammalian cardiac myocyte. J Biol Chem. 1997; 272: 4836-42.
34. Nussler AK, Billiar TR. Inflammation, immunoregulation, and inducible nitric oxide synthase. J Leukoc Biol. 1993; 54: 171-8.
35. Kershaw EE, Flier JS. Adipose tissue as an endocrine organ. J Clin Endocrinol Metab. 2004; 89: 2548-56.
36. Berg AH, Scherer PE. Adipose tissue, inflammation, and cardiovascular disease. Circ Res. 2005; 96: 939-49.
37. Hamilton CA, Miller WH, Al-Benna S, et al. Strategies to reduce oxidative stress in cardiovascular disease. Clin Sci. 2004; 106: 219-34.
38. Mann DL, Young JB. Basic mechanisms in congestive heart failure. Recognizing the role of proinflammatory cytokines. Chest. 1994; 105: 897-904.
39. Seta Y, Shan K, Bozkurt B, et al. Basic mechanisms in heart failure: the cytokine hypothesis. J Card Fail. 1996; 2: 243-9.
40. Stephenson TJ, Broughton Pipkin F. Atrial natriuretic factor: the heart as an endocrine organ. Arch Dis Child. 1990; 65: 1293-4.
41. Feldman AM, Combes A, Wagner D, et al. The role of tumor necrosis factor in the pathophysiology of heart failure. J Am Coll Cardiol. 2000; 35: 537-44.
42. Nian M, Lee P, Khaper N, et al. Inflammatory cytokines and postmyocardial infarction remodeling. Circ Res. 2004; 94: 1543-53.
43. Clark RA, Valente AJ. Nuclear factor kappa B activation by NADPH oxidases. Mech Ageing Dev. 2004; 125: 799-810.