Deficiency of CuZn superoxide dismutase promotes inflammation and alters medial structure following vascular injury

Journal of Atherosclerosis and Thrombosis

Volumn 18, Issue 11, 2011, Pages 1009-1017

  Ishigami, Norio ^a   Isoda, Kikuo ^a   Adachi, Takeshi ^a   Niida, Tomiharu ^a   Kujiraoka, Takehiko ^a   Hakuno, Daihiko ^a   Kondo, Harumi ^a   Kusuhara, Masatoshi ^b   Ohsuzu, Fumitaka ^a  

^a NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

^b SHIZUOKA CANCER CENTER   (Japan)

Author keywords

Copper zinc superoxide dismutase; Cuff injury; Inflammation; Proliferation; Smooth muscle cell

Indexed keywords

CELL ADHESION MOLECULE; COPPER ZINC SUPEROXIDE DISMUTASE; INOSINATE DEHYDROGENASE; INTERCELLULAR ADHESION MOLECULE 1; MESSENGER RNA; SUPEROXIDE; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERY INJURY; ARTICLE; BLOOD VESSEL INJURY; CARDIOVASCULAR INFLAMMATION; CELL INFILTRATION; CONTROLLED STUDY; ENZYME DEFICIENCY; FEMORAL ARTERY; MALE; MORPHOMETRICS; MOUSE; NONHUMAN; PROTEIN EXPRESSION; ROTATOR CUFF INJURY;

EID: 82455189550     PISSN: 13403478     EISSN: 18803873     Source Type: Journal    
DOI: 10.5551/jat.9324     Document Type: Article

References (30)

1. Stocker R, Keaney JF Jr: Role of oxidative modifications in atherosclerosis. Physiol Rev, 2004; 84: 1381-1478
2. Wassmann S, Wassmann K, Nickenig G: Modulation of oxidant and antioxidant enzyme expression and function in vascular cells. Hypertension, 2004; 44: 381-386
3. Kondo T, Hirose M, Kageyama K: Roles of oxidative stress and redox regulation in atherosclerosis. J Atheroscler Thromb, 2009; 16: 532-538
4. Azevedo LC, Pedro MA, Souza LC, de Souza HP, Janiszewski M, da Luz PL, Laurindo FR: Oxidative stress as a signaling mechanism of the vascular response to injury: the redox hypothesis of restenosis. Cardiovasc Res, 2000; 47: 436-445
5. Faraci FM, Didion SP: Vascular protection: superoxide dismutase isoforms in the vessel wall. Arterioscler Thromb Vasc Biol, 2004; 24: 1367-1373
6. Morikawa K, Shimokawa H, Matoba T, Kubota H, Akaie T, Talukder MA, Hatanaka M, Fujiki T, Maeda H, Takahashi S, Takeshita A: Pivotal role of Cu, Zn-superoxide dismutase in endothelium-dependent hyperpolarization. J Clin Invest, 2003; 112: 1871-1879
7. Azumi H, Inoue N, Ohashi Y, Terashima M, Mori T, Fujita H, Awano K, Kobayashi K, Maeda K, Hata K, Shinke T, Kobayashi S, Hirata S, Kawashima S, Itabe H, Hayashi Y, Imajoh-Ohmi S, Itoh H, Yokoyama M: Superoxide generation in directional coronary atherectomy specimens of patients with angina pectoris: important role of NAD(P)H oxidase. Arterioscler Thromb Vasc Biol, 2002; 22: 1838-1844
8. Kobayashi S, Inoue N, Azumi H, Seno T, Hirata K, Kawashima S, Hayashi Y, Itoh H, Yokozaki H, Yokoyama M: Expressional changes of the vascular antioxidant system in atherosclerotic coronary arteries. J Atheroscler Thromb, 2002; 9: 184-190
9. Zanetti M, Sato J, Katusic ZS, O'Brien T: Gene transfer of superoxide dismutase isoforms reverses endothelial dys function in diabetic rabbit aorta. Am J Physiol Heart Circ Physiol, 2001; 280: H2516-H2523
10. Shi M, Yang H, Motley ED, Guo Z: Overexpression of Cu/Zn-superoxide dismutase and/or catalase in mice inhibits aorta smooth muscle cell proliferation. Am J Hypertens, 2004; 17: 450-456
11. Yang H, Roberts LJ, Shi MJ, Zhou LC, Ballard BR, Richardson A, Guo ZM: Retardation of atherosclerosis by overexpression of catalase or both Cu/Zn-superoxide dismutase and catalase in mice lacking apolipoprotein E. Circ Res, 2004; 95: 1075-1081
12. Didion SP, Ryan MJ, Didion LA, Fegan PE, Sigmund CD, Faraci FM: Increased superoxide and vascular dys function in CuZnSOD-deficient mice. Circ Res, 2002; 91: 938-944
13. Matzuk MM, Dionne L, Guo Q, Kumar TR, Lebovitz RM: Ovarian function in superoxide dismutase 1 and 2 knockout mice. Endocrinology, 1998; 139: 4008-4011
14. Isoda K, Nishikawa K, Kamezawa Y, Yoshida M, Kusuhara M, Moroi M, Tada N, Ohsuzu F: Osteopontin plays an important role in the development of medial thickening and neointimal formation. Circ Res, 2002; 91: 77-82
15. Isoda K, Shiigai M, Ishigami N, Matsuki T, Horai R, Nishikawa K, Kusuhara M, Nishida Y, Iwakura Y, Ohsuzu F: Deficiency of interleukin-1 receptor antagonist promotes neointimal formation after injury. Circulation, 2003; 108: 516-518
16. Isoda K, Ohsuzu F: The effect of interleukin-1 receptor antagonist on arteries and cholesterol metabolism. J Atheroscler Thromb, 2006; 13: 21-30
17. Isoda K, Sawada S, Ayaori M, Matsuki T, Horai R, Kagata Y, Miyazaki K, Kusuhara M, Okazaki M, Matsubara O, Iwakura Y, Ohsuzu F: Deficiency of interleukin-1 receptor antagonist deteriorates fatty liver and cholesterol metabolism in hypercholesterolemic mice. J Biol Chem, 2005; 280: 7002-7009
18. Miller FJ Jr, Gutterman DD, Rios CD, Heistad DD, Davidson BL: Superoxide production in vascular smooth muscle contributes to oxidative stress and impaired relaxation in atherosclerosis. Circ Res, 1998; 82: 1298-1305
19. Brandes RP: Out of balance: a role of impaired superoxide dismutase activity for vascular constrictive remodeling after angioplasty. Arterioscler Thromb Vasc Biol, 2003; 23: 2121-2122
20. Ohsuzu F: The roles of cytokines, inflammation and immunity in vascular diseases. J Atheroscler Thromb, 2004; 11: 313-321
21. Kuro-o M, Nagai R, Nakahara K, Katoh H, Tsai RC, Tsuchimochi H, Yazaki Y, Ohkubo A, Takaku F: cDNA cloning of a myosin heavy chain isoform in embryonic smooth muscle and its expression during vascular development and in arteriosclerosis. J Biol Chem, 1991; 266: 3768-3773
22. Liu J, Yang F, Yang XP, Jankowski M, Pagano PJ: NAD(P)H Oxidase Mediates Angiotensin II-Induced Vascular Macrophage Infiltration and Medial Hypertrophy. Arterioscler Thromb Vasc Biol, 2003; 23: 776-782
23. Cayatte AJ, Rupin A, Oliver-Krasinski J, Maitland K, Sansilvestri-Morel P, Boussard MF, Wierzbicki M, Verbeuren TJ, Cohen RA: S17834, a new inhibitor of cell adhesion and atherosclerosis that targets NADPH oxidase. Arterioscler Thromb Vasc Biol, 2001; 21: 1577-1584
24. Lin SJ, Shyue SK, Hung YY, Chen YH, Ku HH, Chen JW, Tam KB, Chen YL: Superoxide dismutase inhibits the expression of vascular cell adhesion molecule-1 and intracellular cell adhesion molecule-1 induced by tumor necrosis factor-alpha in human endothelial cells through the JNK/p38 pathways. Arterioscler Thromb Vasc Biol, 2005; 25: 334-340
25. Wolin MS: Interactions of oxidants with vascular signaling systems. Arterioscler Thromb Vasc Biol, 2000; 20: 1430-1442
26. Griendling KK, FitzGerald GA: Oxidative stress and cardiovascular injury: Part I: basic mechanisms and in vivo monitoring of ROS. Circulation, 2003; 108: 1912-1916
27. Tribble DL, Gong EL, Leeuwenburgh C, Heinecke JW, Carlson EL, Verstuyft JG, Epstein CJ: Fatty streak formation in fat-fed mice expressing human copper-zinc superoxide dismutase. Arterioscler Thromb Vasc Biol, 1997; 17: 1734-1740
28. Leite PF, Danilovic A, Moriel P, Dantas K, Marklund S, Dantas AP, Laurindo FR: Sustained decrease in superoxide dismutase activity underlies constrictive remodeling after balloon injury in rabbits. Arterioscler Thromb Vasc Biol, 2003; 23: 2197-2202
29. Kuo MD, Bright IJ, Wang DS, Ghafouri P, Yuksel E, Hilfiker PR, Miniati DN, Dake MD: Local resistance to oxidative stress by overexpression of copper-zinc superoxide dismutase limits neointimal formation after angioplasty. J Endovasc Ther, 2004; 11: 585-594
30. Hink HU, Santanam N, Dikalov S, McCann L, Nguyen AD, Parthasarathy S, Harrison DG, Fukai T: Peroxidase properties of extracellular superoxide dismutase: role of uric acid in modulating in vivo activity. Arterioscler Thromb Vasc Biol, 2002; 22: 1402-1408