Dissociating behavioral disorders in early dementia-An FDG-PET study

Psychiatry Research - Neuroimaging

Volumn 194, Issue 3, 2011, Pages 235-244

  Schroeter, Matthias L ^a,b   Vogt, Barbara ^a,b   Frisch, Stefan ^a,b   Becker, Georg ^b   Seese, Anita ^b   Barthel, Henryk ^b   Mueller, Karsten ^a   Villringer, Arno ^a,b   Sabri, Osama ^b  

^a MAX PLANCK INSTITUTE FOR HUMAN COGNITIVE AND BRAIN SCIENCES   (Germany)

^b UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

Alzheimer's disease; Apathy; Disinhibition; Eating disorders; Frontotemporal dementia; Semantic dementia

Indexed keywords

FLUORODEOXYGLUCOSE F 18;

ADULT; AGED; ALZHEIMER DISEASE; APATHY; ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; DEMENTIA; DISEASE SEVERITY; DISSOCIATIVE DISORDER; EATING DISORDER; FEMALE; FRONTOTEMPORAL DEMENTIA; GLUCOSE METABOLISM; HUMAN; MALE; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL;

AGED; ANALYSIS OF VARIANCE; BEHAVIORAL SYMPTOMS; BRAIN; BRAIN MAPPING; COGNITION DISORDERS; DEMENTIA; FEMALE; FLUORODEOXYGLUCOSE F18; HUMANS; MALE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; POSITRON-EMISSION TOMOGRAPHY; PSYCHIATRIC STATUS RATING SCALES; REGRESSION ANALYSIS;

EID: 82455187906     PISSN: 09254927     EISSN: 18727506     Source Type: Journal    
DOI: 10.1016/j.pscychresns.2011.06.009     Document Type: Article

References (55)

1. Adenzato M., Cavallo M., Enrici I. Theory of mind ability in the behavioural variant of frontotemporal dementia: an analysis of the neural, cognitive, and social levels. Neuropsychologia 2010, 48:2-12.
2. Al-Adawi S., Dawe G.S., Al-Hussaini A.A. Aboulia: neurobehavioural dysfunction of dopaminergic system?. Medical Hypotheses 2000, 54:523-530.
3. Apostolova L.G., Akopyan G.G., Partiali N., Steiner C.A., Dutton R.A., Hayashi K.M., Dinov I.D., Toga A.W., Cummings J.L., Thompson P.M. Structural correlates of apathy in Alzheimer's disease. Dementia and Geriatric Cognitive Disorders 2007, 24:91-97.
4. Boeve B.F., Lang A.E., Litvan I. Corticobasal degeneration and its relationship to progressive supranuclear palsy and frontotemporal dementia. Annals of Neurology 2003, 54(Suppl. 5):S15-S19.
5. Bruen P.D., McGeown W.M., Shanks M.F., Venneri A. Neuroanatomical correlates of neuropsychiatric symptoms in Alzheimer's disease. Brain 2008, 131:2455-2463.
6. Chételat G., Desgranges B., Landeau B., Mézenge F., Poline J.B., de la Sayette V., Viader F., Eustache F., Baron J.C. Direct voxel-based comparison between grey matter hypometabolism and atrophy in Alzheimer's disease. Brain 2008, 131:60-71.
7. Cummings J.L. The neuropsychiatric inventory: assessing psychopathology in dementia patients. Neurology 1997, 48:S10-S16.
8. Drzezga A., Grimmer T., Henriksen G., Stangier I., Perneczky R., Diehl-Schmid J., Mathis C.A., Klunk W.E., Price J., DeKosky S., Wester H.J., Schwaiger M., Kurz A. Imaging of amyloid plaques and cerebral glucose metabolism in semantic dementia and Alzheimer's disease. NeuroImage 2008, 39:619-633.
9. Dubois B., Feldman H.H., Jacova C., DeKosky S.T., Barberger-Gateau P., Cummings J., Delacourte A., Galasko D., Gauthier S., Jicha G., Meguro K., O'Brien J., Pasquier F., Robert P., Rossor M., Salloway S., Stern Y., Visser P.J., Scheltens P. Research criteria for the diagnosis of Alzheimer's disease: revising the NINCDS-ADRDA criteria. Lancet Neurology 2007, 6:734-746.
10. Dukart J., Mueller K., Horstmann A., Vogt B., Frisch S., Barthel H., Becker G., Möller H.E., Villringer A., Sabri O., Schroeter M.L. Differential effects of global and cerebellar normalization on detection and differentiation of dementia in FDG-PET studies. NeuroImage 2010, 49:1490-1495.
11. Dukart J., Mueller K., Horstmann A., Barthel H., Möller H.E., Villringer A., Sabri O., Schroeter M.L. Combined evaluation of FDG-PET and MRI improves detection and differentiation of dementia. PloS One 2011, 6:e18111.
12. Franceschi M., Anchisi D., Pelati O., Zuffi M., Matarrese M., Fazio F., Perani D. Glucose metabolism and serotonin receptors in the frontotemporal lobe degeneration. Annals of Neurology 2005, 57:216-225.
13. Gorno-Tempini M.L., Dronkers N.F., Rankin K.P., Ogar J.M., Phengrasamy L., Rosen H.J., Johnson J.K., Weiner M.W., Miller B.L. Cognition and anatomy in three variants of primary progressive aphasia. Annals of Neurology 2004, 55:335-346.
14. Guimaraes H.C., Levy R., Teixeira A.L., Beato R.G., Caramelli P. Neurobiology of apathy in Alzheimer's disease. Arquivos de neuro-psiquiatria 2008, 66:436-443.
15. Holthoff V.A., Beuthien-Baumann B., Kalbe E., Lüdecke S., Lenz O., Zündorf G., Spirling S., Schierz K., Winiecki P., Sorbi S., Herholz K. Regional cerebral metabolism in early Alzheimer's disease with clinically significant apathy or depression. Biological Psychiatry 2005, 57:412-421.
16. Huey E.D., Putnam K.T., Grafman J. A systematic review of neurotransmitter deficits and treatments in frontotemporal dementia. Neurology 2006, 66:17-22.
17. Ishii K., Willoch F., Minoshima S., Drzezga A., Ficaro E.P., Cross D.J., Kuhl D.E., Schwaiger M. Statistical brain mapping of 18F-FDG PET in Alzheimer's disease: validation of anatomic standardization for atrophied brains. Journal of Nuclear Medicine 2001, 42:548-557.
18. Jessen F., Wiese B., Bachmann C., Eifflaender-Gorfer S., Haller F., Kölsch H., Luck T., Mösch E., van den Bussche H., Wagner M., Wollny A., Zimmermann T., Pentzek M., Riedel-Heller S.G., Romberg H.P., Weyerer S., Kaduszkiewicz H., Maier W., Bickel H. German study on aging, cognition and dementia in primary care patients study group. Archives of General Psychiatry 2010, 67:414-422.
19. Lanctot K.L., Herrmann N., Black S.E., Ryan M., Rothenburg L.S., Liu B.A., Busto U.E. Apathy associated with Alzheimer disease: use of dextroamphetamine challenge. The American Journal of Geriatric Psychiatry 2008, 16:551-557.
20. Le Ber I., Guedj E., Gabelle A., Verpillat P., Volteau M., Thomas-Anterion C., Decousus M., Hannequin D., Vera P., Lacomblez L., Camuzat A., Didic M., Puel M., Lotterie J.A., Golfier V., Bernard A.M., Vercelletto M., Magne C., Sellal F., Namer I., Michel B.F., Pasquier J., Salachas F., Bochet J. Demographic, neurological and behavioural characteristics and brain perfusion SPECT in frontal variant of frontotemporal dementia. Brain 2006, 129:3051-3065.
21. Liu W., Miller B.L., Kramer J.H., Rankin K., Wyss-Coray C., Gearhart R., Phengrasamy L., Weiner M., Rosen H.J. Behavioral disorders in the frontal and temporal variants of frontotemporal dementia. Neurology 2004, 62:742-748.
22. Luckhaus C., Cohnen M., Flüβ M.O., Jänner M., Grass-Kapanke B., Teipel S.J., Grothe M., Hampel H., Peters O., Kornhuber J., Maier W., Supprian T., Gaebel W., Mödder U., Wittsack H.J. The relation of regional cerebral perfusion and atrophy in mild cognitive impairment (MCI) and early Alzheimer's dementia. Psychiatry Research Neuroimaging 2010, 183:44-51.
23. Marin R.S., Wilkosz P.A. Disorders of diminished motivation. The Journal of Head Trauma Rehabilitation 2005, 20:377-388.
24. Marshall G.A., Monserratt L., Harwood D., Mandelkern M., Cummings J.L., Sultzer D.L. Positron emission tomography metabolic correlates of apathy in Alzheimer disease. Archives of Neurology 2007, 64:1015-1020.
25. Mathias J.L., Morphett K. Neurobehavioral differences between Alzheimer's disease and frontotemporal dementia: a meta-analysis. Journal of Clinical and Experimental Neuropsychology 2010, 32:682-698.
26. McKeith I.G., Galasko D., Kosaka K., Perry E.K., Dickson D.W., Hansen L.A., Salmon D.P., Lowe J., Mirra S.S., Byrne E.J., Lennox G., Quinn N.P., Edwardson J.A., Ince P.G., Bergeron C., Burns A., Miller B.L., Lovestone S., Collerton D., Jansen E.N.H., Ballard C., deVos R.A.I., Wilcock G.K., Jellinger K.A., Perry R.H. Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies. Report of the consortium on DLB international workshop. Neurology 1996, 47:1113-1124.
27. McKhann G., Drachman D., Folstein M., Katzman R., Price D., Stadlan E.M. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984, 34:939-944.
28. Mendez M.F., Ghajarania M., Perryman K.M. Posterior cortical atrophy: clinical characteristics and differences compared to Alzheimer's disease. Dementia and Geriatric Cognitive Disorders 2002, 14:33-40.
29. Migneco O., Benoit M., Koulibali P.M., Dygai I., Bertogliati C., Desvignes P., Robert P.H., Meladain G., Bussiere F., Darcourt J. Perfusion brain SPECT and statistical parametric mapping analysis indicate that apathy is a cingulate syndrome: a study in Alzheimer's disease and nondemented patients. NeuroImage 2001, 13:896-902.
30. Morris J.C. Clinical dementia rating: a reliable and valid diagnostic and staging measure for dementia of the Alzheimer type. International Psychogeriatrics 1997, 9:173-178.
31. Neary D., Snowden J.S., Gustafson L., Passant U., Stuss D., Black S., Freedman M., Kertesz A., Robert P.H., Albert M., Boone K., Miller B.L., Cummings J., Benson D.F. Frontotemporal lobar degeneration: a consensus on clinical diagnostic criteria. Neurology 1998, 51:1546-1554.
32. Nichols T., Brett M., Anderson J., Wager T., Poline J.B. Valid conjunction inference with the minimum statistic. NeuroImage 2004, 25:653-660.
33. Olson I.R., Plotzker A., Ezzyat Y. The enigmatic temporal pole: a review of findings on social and emotional processing. Brain 2007, 130:1718-1731.
34. Peters F., Perani D., Herholz K., Holthoff V., Beuthien-Baumann B., Sorbi S., Pupi A., Degueldre C., Lemaire C., Collette F., Salmon E. Orbitofrontal dysfunction related to both apathy and disinhibition in frontotemporal dementia. Dementia and Geriatric Cognitive Disorders 2006, 21:373-379.
35. Raczka K.A., Becker G., Seese A., Frisch S., Heiner S., Marschhauser A., Barthel H., Scheid R., Sabri O., Schroeter M.L. Executive and behavioral deficits share common neural substrates in frontotemporal lobar degeneration-a pilot FDG-PET study. Psychiatry Research Neuroimaging 2010, 182:274-280.
36. Rankin K.P., Gorno-Tempini M.L., Allison S.C., Stanley C.M., Glenn S., Weiner M.W., Miller B.L. Structural anatomy of empathy in neurodegenerative disease. Brain 2006, 129:2945-2956.
37. Rosen H.J., Allison S.C., Schauer G.F., Gorno-Tempini M.L., Weiner M.W., Miller B.L. Neuroanatomical correlates of behavioural disorders in dementia. Brain 2005, 128:2612-2625.
38. Salmon E., Lekeu F., Bastin C., Garraux G., Collette F. Functional imaging of cognition in Alzheimer's disease using positron emission tomography. Neuropsychologia 2008, 46:1613-1623.
39. Schroeter M.L., Ettrich B., Schwier C., Scheid R., Guthke T., von Cramon D.Y. Diffuse axonal injury due to traumatic brain injury alters inhibition of imitative response tendencies. Neuropsychologia 2007, 45:3149-3156.
40. Schroeter M.L., Raczka K., Neumann J., von Cramon D.Y. Towards a nosology for frontotemporal lobar degenerations-a meta-analysis involving 267 subjects. NeuroImage 2007, 36:497-510.
41. Schroeter M.L., Raczka K., Neumann J., von Cramon D.Y. Neural networks in frontotemporal dementia-a meta-analysis. Neurobiology of Aging 2008, 29:418-426.
42. Schroeter M.L., Stein T., Maslowski N., Neumann J. Neural correlates of Alzheimer's disease and mild cognitive impairment: a systematic and quantitative meta-analysis involving 1351 patients. NeuroImage 2009, 47:1196-1206.
43. Schroeter M.L., Ettrich B., Menz M., Zysset S. Traumatic brain injury affects the frontomedian cortex-an event-related fMRI study on evaluative judgments. Neuropsychologia 2010, 48:185-193.
44. Seeley W.W., Crawford R.K., Zhou J., Miller B.L., Greicius M.D. Neurodegenerative diseases target large-scale human brain networks. Neuron 2009, 62:42-52.
45. Starkstein S.E., Jorge R., Mizrahi R., Robinson R.G. A prospective longitudinal study of apathy in Alzheimer's disease. Journal of Neurology, Neurosurgery, and Psychiatry 2006, 77:8-11.
46. Teipel S.J., Ewers M., Wolf S., Jessen F., Kölsch H., Arlt S., Luckhaus C., Schönknecht P., Schmidtke K., Heuser I., Frölich L., Ende G., Pantel J., Wiltfang J., Rakebrandt F., Peters O., Born C., Kornhuber J., Hampel H. Multicentre variability of MRI-based medial temporal lobe volumetry in Alzheimer's disease. Psychiatry Research: Neuroimaging 2010, 182:244-250.
47. Uher R., Treasure J. Brain lesions and eating disorders. Journal of Neurology, Neurosurgery, and Psychiatry 2005, 76:852-857.
48. van der Zee J., Sleegers K., van Broeckhoven C. The Alzheimer disease-frontotemporal lobar degeneration spectrum. Neurology 2008, 71:1191-1197.
49. Villain N., Desgranges B., Viader F., de la Sayette V., Mézenge F., Landeau B., Baron J.C., Eustache F., Chételat G. Relationships between hippocampal atrophy, white matter disruption, and gray matter hypometabolism in Alzheimer's Disease. Journal of Neuroscience 2008, 28:6174-6181.
50. Whitwell J.L., Sampson E.L., Loy C.T., Warren J.E., Rossor M.N., Fox N.C., Warren J.D. VBM signatures of abnormal eating behaviours in frontotemporal lobar degeneration. NeuroImage 2007, 35:207-213.
51. Williams G.B., Nestor P.J., Hodges J.R. Neural correlates of semantic and behavioural deficits in frontotemporal dementia. NeuroImage 2005, 24:1042-1051.
52. Winblad B., Palmer K., Kivipelto M., Jelic V., Fratiglioni L., Wahlund L.O., Nordberg A., Backman L., Albert M., Almkvist O., Arai H., Basun H., Blennow K., de Leon M., DeCarli C., Erkinjuntti T., Giacobini E., Graff C., Hardy J., Jack C., Jorm A., Ritchie K., van Duijn C., Visser P., Petersen R.C. Mild cognitive impairment: beyond controversies, towards a consensus-report of the International Working Group on Mild Cognitive Impairment. Journal of Internal Medicine 2004, 256:240-246.
53. Woolley J.D., Gorno-Tempini M.L., Seeley W.W., Rankin K., Lee S.S., Matthews B.R., Miller B.L. Binge eating is associated with right orbitofrontal-insular-striatal atrophy in frontotemporal dementia. Neurology 2007, 69:1424-1433.
54. Yakushev I., Landvogt C., Buchholz H.G., Fellgiebel A., Hammers A., Scheurich A., Schmidtmann I., Gerhard A., Schreckenberger M., Bartenstein P. Choice of reference area in studies of Alzheimer's disease using positron emission tomography with fluorodeoxyglucose-F18. Psychiatry Research: Neuroimaging 2008, 164:143-153.
55. Zamboni G., Huey E.D., Krueger F., Nichelli P.F., Grafman J. Apathy and disinhibition in frontotemporal dementia. Neurology 2008, 71:736-742.