Simultaneous introduction of a novel high fat diet and wheel running induces anorexia

Physiology and Behavior

Volumn 105, Issue 4, 2012, Pages 909-914

  Scarpace, E T ^a   Matheny, M ^a   Strehler, K Y E ^a   Shapiro, A ^a   Cheng, K Y ^a   Tumer N ^a,b   Scarpace, P J ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Anorexia; High fat feeding; Voluntary wheel running

Indexed keywords

AGE; ANIMAL EXPERIMENT; ANOREXIA; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; FOOD INTAKE; LIPID DIET; MALE; NONHUMAN; PHYSICAL ACTIVITY; PRIORITY JOURNAL; RAT; TREADMILL; WEIGHT REDUCTION;

AGE FACTORS; ANIMALS; ANOREXIA; DIETARY FATS; DISEASE MODELS, ANIMAL; FEEDING BEHAVIOR; MALE; MOTOR ACTIVITY; RATS; RATS, INBRED F344; TIME FACTORS;

EID: 82455162837     PISSN: 00319384     EISSN: 1873507X     Source Type: Journal    
DOI: 10.1016/j.physbeh.2011.11.011     Document Type: Article

References (13)

1. Casper R., Sullivan E., Tecott L. Relevance of animal models to human eating disorders and obesity. Psychopharmacology (Berl) 2008, 199:313-329.
2. Cota D., Barrera J.G., Seeley R.J. Leptin in energy balance and reward: two faces of the same coin?. Neuron 2006, 51(6):678-680.
3. Prats E., Monfar M., Castella J., Iglesias R., Alemany M. Energy intake of rats fed a cafeteria diet. Physiol Behav 1989, 45(2):263-272.
4. Scarpace P.J., Matheny M., Zhang Y. Wheel running eliminates high-fat preference and enhances leptin signaling in the ventral tegmental area. Physiol Behav 2010, 100:173-179.
5. Pierce W.D., Epling W.F., Boer D.P. Deprivation and satiation: the interrelations between food and wheel running. J Exp Anal Behav 1986, 46(2):199-210.
6. de Visser L., van den Bos R., Stoker A.K., Kas M.J., Spruijt B.M. Effects of genetic background and environmental novelty on wheel running as a rewarding behaviour in mice. Behav Brain Res 2007, 177(2):290-297.
7. Hillebrand J.J.G., Kas M.J.H., van Elburg A.A., Hoek H.W., Adan R.A.H. Leptin's effect on hyperactivity: Potential downstream effector mechanisms. Physiol Behav 2008, 94:689-695.
8. Judge M.K., Zhang J., Tumer N., Carter C., Daniels M.J., Scarpace P.J. Prolonged hyperphagia with high-fat feeding contributes to exacerbated weight gain in rats with adult-onset obesity. Am J Physiol Regul Integr Comp Physiol 2008, 295(3):R773-R780.
9. Schwartz R.S. Obesity in the elderly. Handbook of obesity 1998, 103-114. Marcel Dekker, New York. B.C. Bray, W.P.T. James (Eds.).
10. Wolden-Hanson T., Marck B.T., Matsumoto A.M. Blunted hypothalamic neuropeptide gene expression in response to fasting, but preservation of feeding responses to AgRP in aging male Brown Norway rats. Am J Physiol Regul Integr Comp Physiol 2004, 287(1):R138-R146.
11. Matheny M., Shapiro A., Tümer N., Scarpace P.J. Region-specific diet-induced and leptin-induced cellular leptin resistance includes the ventral tegmental area in rats. Neuropharmacology 2011, 60:480-487.
12. Matheny M., Zhang Y., Shapiro A., Tümer N., Scarpace P.J. Central overexpression of leptin antagonist reduces wheel running and underscores importance of endogenous leptin receptor activity in energy homeostasis. Am J Physiol Regul Integr Comp Physiol 2009, 297:R1254-R1261.
13. Adan R.A.H., Hillebrand J.J.G., Danner U.N., Cano S.C., Kas M.J.H., Verhagen L.A.W. Neurobiology driving hyperactivity in activity-based anorexia. Curr Top Behav Neurosci 2011, 6:229-250.