Improvement of cognitive flexibility and cingulate blood flow correlates after atypical antipsychotic treatment in drug-naive patients with first-episode schizophrenia

Psychiatry Research - Neuroimaging

Volumn 194, Issue 3, 2011, Pages 205-211

  Pardo, Bernardo M ^a,b   Garolera, Maite ^c   Ariza, Mar ^a,d   Pareto, Deborah ^e   Salamero, Manel ^f   Valles, Vicenç ^c   Delgado, Luis ^c   Alberni, Joan ^c  

^a UNIVERSITY OF BARCELONA   (Spain)

^b PARC SANITARI SANT JOAN DE DÉU   (Spain)

^c Brain   (Spain)

^d Institute for Brain Cognition and Behaviour (IR3C)   (Spain)

^e BIOMATERIALES Y NANOMEDICINA CIBER BBN   (Spain)

^f HOSPITAL CLÍNIC   (Spain)

Author keywords

Cerebral blood flow; Cognition; Functional neuroimaging; Second generation antipsychotics

Indexed keywords

ATYPICAL ANTIPSYCHOTIC AGENT;

ADULT; ANTERIOR CINGULATE; ARTICLE; BRAIN BLOOD FLOW; BRAIN PERFUSION; CLINICAL ARTICLE; COGNITION; CONTROLLED STUDY; FEMALE; HUMAN; MALE; NEUROIMAGING; PRIORITY JOURNAL; SCHIZOPHRENIA; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; TASK PERFORMANCE;

ADOLESCENT; ADULT; ANTIPSYCHOTIC AGENTS; ATTENTION; BRAIN MAPPING; CEREBROVASCULAR CIRCULATION; COGNITION DISORDERS; CYSTEINE; FEMALE; GYRUS CINGULI; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; NEUROPSYCHOLOGICAL TESTS; ORGANOTECHNETIUM COMPOUNDS; PSYCHIATRIC STATUS RATING SCALES; SCHIZOPHRENIA; STATISTICS AS TOPIC; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; YOUNG ADULT;

EID: 82455162350     PISSN: 09254927     EISSN: 18727506     Source Type: Journal    
DOI: 10.1016/j.pscychresns.2011.06.001     Document Type: Article

References (62)

1. Aarts E., Roelofs A., van Turennout M. Attentional control of task and response in lateral and medial frontal cortex: brain activity and reaction time distributions. Neuropsychologia 2009, 47:2089-2099.
2. Akdede B.B., Anil Yagcioglu A.E., Alptekin K., Turgut T.I., Tumuklu M., Yazici M.K., Jayathilake K., Tunca Z., Gogus A., Meltzer H.Y. A double-blind study of combination of clozapine with risperidone in patients with schizophrenia: effects on cognition. The Journal of Clinical Psychiatry 2006, 67:1912-1919.
3. Aubin G., Stip E., Gelinas I., Rainville C., Chapparo C. Daily activities, cognition and community functioning in persons with schizophrenia. Schizophrenia Research 2009, 107:313-318.
4. Badzakova-Trajkov G., Barnett K.J., Waldie K.E., Kirk I.J. An ERP investigation of the Stroop task: the role of the cingulate in attentional allocation and conflict resolution. Brain Research 2009, 1253:139-148.
5. Bernal B., Altman N. Neural networks of motor and cognitive inhibition are dissociated between brain hemispheres: an fMRI study. International Journal of Neuroscience 2009, 119:1848-1880.
6. Bobes J., Arango C., Garcia-Garcia M., Rejas J. Prevalence of negative symptoms in outpatients with schizophrenia spectrum disorders treated with antipsychotics in routine clinical practice: findings from the CLAMORS study. The Journal of Clinical Psychiatry 2009, 71:280-286.
7. Borges A., San Luis C., Sánchez-Bruno A. Dominance statistics: a simulation study of the d statistic. Quality and Quantity 2003, 37:303-316.
8. Brewer W.J., Yucel M., Harrison B.J., McGorry P.D., Olver J., Egan G.F., Velakoulis D., Pantelis C. Increased prefrontal cerebral blood flow in first-episode schizophrenia following treatment: longitudinal positron emission tomography study. The Australian and New Zealand Journal of Psychiatry 2007, 41:129-135.
9. Camchong J., MacDonald A.W., Bell C., Mueller B.A., Lim K.O. Altered functional and anatomical connectivity in schizophrenia. Schizophrenia Bulletin 2011, 37(3):640-650.
10. Catale C., Marique P., Closset A., Meulemans T. Attentional and executive functioning following mild traumatic brain injury in children using the Test for Attentional Performance (TAP) battery. Journal of Clinical and Experimental Neuropsychology 2009, 31:331-338.
11. Cliff N. Dominance statistics: ordinal analyses to answer ordinal questions. Psychological Bulletin 1993, 114:494-509.
12. Cliff N. Answering ordinal questions with ordinal data using ordinal statistics. Multivariate Behavioral Research 1996, 31:331-350.
13. Cremasco L., Cappa S.F. Attentional dysfunction of chronic schizophrenia: No association with long-term institutionalization. Psychiatry and Clinical Neurosciences 2002, 56:419-423.
14. Crespo-Facorro B., Rodriguez-Sanchez J.M., Perez-Iglesias R., Mata I., Ayesa R., Ramirez-Bonilla M., Martinez-Garcia O., Vazquez-Barquero J.L. Neurocognitive effectiveness of haloperidol, risperidone, and olanzapine in first-episode psychosis: a randomized, controlled 1-year follow-up comparison. The Journal of Clinical Psychiatry 2009, 70:717-729.
15. Cuesta M.J., Jalon E.G., Campos M.S., Peralta V. Cognitive effectiveness of olanzapine and risperidone in first-episode psychosis. The British Journal of Psychiatry 2009, 194:439-445.
16. Davidson M., Galderisi S., Weiser M., Werbeloff N., Fleischhacker W.W., Keefe R.S., Boter H., Keet I.P., Prelipceanu D., Rybakowski J.K., Libiger J., Hummer M., Dollfus S., Lopez-Ibor J.J., Hranov L.G., Gaebel W., Peuskens J., Lindefors N., Riecher-Rossler A., Kahn R.S. Cognitive effects of antipsychotic drugs in first-episode schizophrenia and schizophreniform disorder: a randomized, open-label clinical trial (EUFEST). The American Journal of Psychiatry 2009, 166:675-682.
17. de la Torre J.C., Barrios M., Junque C. Frontal lobe alterations in schizophrenia: neuroimaging and neuropsychological findings. European Archives of Psychiatry and Clinical Neuroscience 2005, 255:236-244.
18. Goldberg T.E., Goldman R.S., Burdick K.E., Malhotra A.K., Lencz T., Patel R.C., Woerner M.G., Schooler N.R., Kane J.M., Robinson D.G. Cognitive improvement after treatment with second-generation antipsychotic medications in first-episode schizophrenia: is it a practice effect?. Archives of General Psychiatry 2007, 64:1115-1122.
19. Gonzalez-Blanch C., Crespo-Facorro B., Alvarez-Jimenez M., Rodriguez-Sanchez J.M., Perez-Iglesias R., Pelayo-Teran J.M., Martinez-Garcia O., Vazquez-Barquero J.L. Lack of association between clinical and cognitive change in first-episode psychosis: the first 6weeks of treatment. Canadian Journal of Psychiatry 2008, 53:839-847.
20. Gurpegui M., Alvarez E., Bousono M., Ciudad A., Carlos G.J., Olivares J.M. Effect of olanzapine or risperidone treatment on some cognitive functions in a one-year follow-up of schizophrenia outpatients with prominent negative symptoms. European Neuropsychopharmacology 2007, 17:725-734.
21. Harvey P.D., Patterson T.L., Potter L.S., Zhong K., Brecher M. Improvement in social competence with short-term atypical antipsychotic treatment: a randomized, double-blind comparison of quetiapine versus risperidone for social competence, social cognition, and neuropsychological functioning. The American Journal of Psychiatry 2006, 163:1918-1925.
22. Houthoofd S.A., Morrens M., Sabbe B.G. Cognitive and psychomotor effects of risperidone in schizophrenia and schizoaffective disorder. Clinical Therapeutics 2008, 30:1565-1589.
23. Hyafil A., Summerfield C., Koechlin E. Two mechanisms for task switching in the prefrontal cortex. Journal of Neuroscience 2009, 29:5135-5142.
24. Jones H.M., Brammer M.J., O'Toole M., Taylor T., Ohlsen R.I., Brown R.G., Purvis R., Williams S., Pilowsky L.S. Cortical effects of quetiapine in first-episode schizophrenia: a preliminary functional magnetic resonance imaging study. Biological Psychiatry 2004, 56:938-942.
25. Keedy S.K., Rosen C., Khine T., Rajarethinam R., Janicak P.G., Sweeney J.A. An fMRI study of visual attention and sensorimotor function before and after antipsychotic treatment in first-episode schizophrenia. Psychiatry Research 2009, 172:16-23.
26. Keefe R.S., Young C.A., Rock S.L., Purdon S.E., Gold J.M., Breier A. One-year double-blind study of the neurocognitive efficacy of olanzapine, risperidone, and haloperidol in schizophrenia. Schizophrenia Research 2006, 81:1-15.
27. Kerns J.G., Cohen J.D., MacDonald A.W., Johnson M.K., Stenger V.A., Aizenstein H., Carter C.S. Decreased conflict- and error-related activity in the anterior cingulate cortex in subjects with schizophrenia. The American Journal of Psychiatry 2005, 162:1833-1839.
28. Krabbendam L., O'Daly O., Morley L.A., van Os J., Murray R.M., Shergill S.S. Using the Stroop task to investigate the neural correlates of symptom change in schizophrenia. British Journal of Psychiatry 2009, 194:373-374.
29. Lahr D., Beblo T., Hartje W. Cognitive performance and subjective complaints before and after remission of major depression. Cognitive Neuropsychiatry 2007, 12:25-45.
30. Lahti A.C., Weiler M.A., Holcomb H.H., Tamminga C.A., Cropsey K.L. Modulation of limbic circuitry predicts treatment response to antipsychotic medication: a functional imaging study in schizophrenia. Neuropsychopharmacology 2009, 34:2675-2690.
31. Lipkovich I.A., Deberdt W., Csernansky J.G., Buckley P., Peuskens J., Kollack-Walker S., Rotelli M., Houston J.P. Defining "good" and "poor" outcomes in patients with schizophrenia or schizoaffective disorder: a multidimensional data-driven approach. Psychiatry Research 2009, 170:161-167.
32. Lysaker P.H., Tsai J., Henninger L.L., Vohs J.L., Viverito K. Decrements in sustained attention across trials in a continuous performance test: associations with social functioning in schizophrenia. The Journal of Nervous and Mental Disease 2010, 198:154-158.
33. Manes F., Villamil A.R., Ameriso S., Roca M., Torralva T. "Real life" executive deficits in patients with focal vascular lesions affecting the cerebellum. Journal of the Neurological Sciences 2009, 283:95-98.
34. Matthias E., Schandry R., Duschek S., Pollatos O. On the relationship between interoceptive awareness and the attentional processing of visual stimuli. International Journal of Psychophysiology 2009, 72:154-159.
35. Milham M.P., Banich M.T., Barad V. Competition for priority in processing increases prefrontal cortex's involvement in top-down control: an event-related fMRI study of the stroop task. Brain Research. Cognitive Brain Research 2003, 17:212-222.
36. Minzenberg M.J., Laird A.R., Thelen S., Carter C.S., Glahn D.C. Meta-analysis of 41 functional neuroimaging studies of executive function in schizophrenia. Archives of General Psychiatry 2009, 66:811-822.
37. Moll J., Oliveira-Souza R., Moll F.T., Bramati I.E., Andreiuolo P.A. The cerebral correlates of set-shifting: an fMRI study of the trail making test. Arquivos de Neuro-Psiquiatria 2002, 60:900-905.
38. Montaldi D., Mayes A.R. The neuroactivation of cognitive processes investigated with SPECT. Behavioural Neurology 2000, 12:53-67.
39. Mulert C., Gallinat J., Dorn H., Herrmann W.M., Winterer G. The relationship between reaction time, error rate and anterior cingulate cortex activity. International Journal of Psychophysiology 2003, 47:175-183.
40. O'Grada C., Dinan T. Executive function in schizophrenia: what impact do antipsychotics have?. Human Psychopharmacology 2007, 22:397-406.
41. Ohira H., Ichikawa N., Nomura M., Isowa T., Kimura K., Kanayama N., Fukuyama S., Shinoda J., Yamada J. Brain and autonomic association accompanying stochastic decision-making. NeuroImage 2010, 49:1024-1037.
42. Pavia J., Ros D., Catafau A.M., Lomena F.J., Huguet M., Setoain J. Three-dimensional realignment of activation brain single-photon emission tomographic studies. European Journal of Nuclear Medicine 1994, 21:1298-1302.
43. Penades R., Boget T., Salamero M., Catarineu S., Bernardo M. Neuropsychological changes in schizophrenia and its modification. Actas Españolas de Psiquiatría 2000, 28:59-69.
44. Pflueger M.O., Gschwandtner U., Stieglitz R.D., Riecher-Rossler A. Neuropsychological deficits in individuals with an at risk mental state for psychosis-working memory as a potential trait marker. Schizophrenia Research 2007, 97:14-24.
45. Polli F.E., Barton J.J., Thakkar K.N., Greve D.N., Goff D.C., Rauch S.L., Manoach D.S. Reduced error-related activation in two anterior cingulate circuits is related to impaired performance in schizophrenia. Brain 2008, 131:971-986.
46. Prouteau A., Doron J. Cognitive predictors of the community functioning dimensions in schizophrenia: state of the art and future directions. L'Encéphale 2008, 34:360-368.
47. Reske M., Habel U., Kellermann T., Backes V., Jon S.N., von Wilmsdorff M., Gaebel W., Zilles K., Schneider F. Differential brain activation during facial emotion discrimination in first-episode schizophrenia. Journal of Psychiatric Research 2009, 43:592-599.
48. Rocca P., Montemagni C., Castagna F., Giugiario M., Scalese M., Bogetto F. Relative contribution of antipsychotics, negative symptoms and executive functions to social functioning in stable schizophrenia. Progress in Neuro-Psychopharmacology & Biological Psychiatry 2009, 33:373-379.
49. Sabri O., Owega A., Schreckenberger M., Sturz L., Fimm B., Kunert P., Meyer P.T., Sander D., Klingelhofer J. A truly simultaneous combination of functional transcranial Doppler sonography and H(2)(15)O PET adds fundamental new information on differences in cognitive activation between schizophrenics and healthy control subjects. Journal of Nuclear Medicine 2003, 44:671-681.
50. Salgado-Pineda P., Caclin A., Baeza I., Junque C., Bernardo M., Blin O., Fonlupt P. Schizophrenia and frontal cortex: where does it fail?. Schizophrenia Research 2007, 91:73-81.
51. Salgado-Pineda P., Junque C., Vendrell P., Baeza I., Bargallo N., Falcon C., Bernardo M. Decreased cerebral activation during CPT performance: structural and functional deficits in schizophrenic patients. NeuroImage 2004, 21:840-847.
52. Salgado-Pineda P., Vendrell P., Bargallo N., Falcon C., Junque C. Functional magnetic resonance in the evaluation of the activity of the anterior cingulate cortex using Stroop's paradigm. Revista de Neurologia 2002, 34:607-611.
53. Scherwath A., Poppelreuter M., Weis J., Schulz-Kindermann F., Koch U., Mehnert A. Psychometric evaluation of a neuropsychological test battery measuring cognitive dysfunction in cancer patients-recommendations for a screening tool. Fortschritte der Neurologie-Psychiatrie 2008, 76:583-593.
54. Schlagenhauf F., Dinges M., Beck A., Wustenberg T., Friedel E., Dembler T., Sarkar R., Wrase J., Gallinat J., Juckel G., Heinz A. Switching schizophrenia patients from typical neuroleptics to aripiprazole: effects on working memory dependent functional activation. Schizophrenia Research 2010, 118:189-200.
55. Snitz B.E., MacDonald A., Cohen J.D., Cho R.Y., Becker T., Carter C.S. Lateral and medial hypofrontality in first-episode schizophrenia: functional activity in a medication-naive state and effects of short-term atypical antipsychotic treatment. The American Journal of Psychiatry 2005, 162:2322-2329.
56. Tana M.G., Montin E., Cerutti S., Bianchi A.M. Exploring cortical attentional system by using fMRI during a Continuous Perfomance Test. Computational Intelligence and Neuroscience 2010, 10.1155/2010/329213.
57. Tislerova B., Brunovsky M., Horacek J., Novak T., Kopecek M., Mohr P., Krajca V. LORETA functional imaging in antipsychotic-naive and olanzapine-, clozapine- and risperidone-treated patients with schizophrenia. Neuropsychobiology 2008, 58:1-10.
58. Vargha A., Delaney H. A critique and improvement of the CL common language effect size statistics of McGraw and Wong. Journal of Educational and Behavioral Statistics 2000, 25:101-132.
59. Williams L.M., Whitford T.J., Flynn G., Wong W., Liddell B.J., Silverstein S., Galletly C., Harris A.W., Gordon E. General and social cognition in first episode schizophrenia: identification of separable factors and prediction of functional outcome using the IntegNeuro test battery. Schizophrenia Research 2008, 99:182-191.
60. Yucel M., Brewer W.J., Harrison B.J., Fornito A., O'Keefe G.J., Olver J., Scott A.M., Egan G.F., Velakoulis D., McGorry P.D., Pantelis C. Anterior cingulate activation in antipsychotic-naive first-episode schizophrenia. Acta Psychiatrica Scandinavica 2007, 115:155-158.
61. Zavitsanou K., Huang X.F. Decreased [(3)H]spiperone binding in the anterior cingulate cortex of schizophrenia patients: an autoradiographic study. Neuroscience 2002, 109:709-716.
62. Zimmermann P., Fimm B. A test battery for attentional performance. Applied Neuropsychology of Attention. Theory, Diagnosis and Rehabilitation 2002, 110-151. Psychology Press, London. P. Zimmermann, M. Leclercq (Eds.).