FHL2 expression in peritumoural fibroblasts correlates with lymphatic metastasis in sporadic but not in HNPCC-associated colon cancer

Laboratory Investigation

Volumn 91, Issue 12, 2011, Pages 1695-1705

  Gullotti, Lucia ^a   Czerwitzki, Jacqueline ^b   Kirfel, Jutta ^a   Propping, Peter ^a   Rahner, Nils ^a   Steinke, Verena ^a   Kahl, Philip ^b   Engel, Christoph ^c   Schüle, Roland ^d   Buettner, Reinhard ^b   Friedrichs, Nicolaus ^b  

^a UNIVERSITY OF BONN   (Germany)

^b UNIVERSITY OF COLOGNE   (Germany)

^c UNIVERSITY OF LEIPZIG   (Germany)

^d UNIVERSITY OF FREIBURG   (Germany)

Author keywords

FHL2; HNPCC; metastasis; peritumoural fibroblast; sporadic colon cancer; TGF b1

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; FOUR AND A HALF LIM DOMAIN PROTEIN 2; LIM PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ADULT; ANIMAL CELL; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CANCER INVASION; CANCER TISSUE; CELL ASSAY; CELL CONTACT; CELL DIFFERENTIATION; CELL MIGRATION; CELL MOTILITY; COCULTURE; COLON CANCER; COLON CARCINOMA; CONTROLLED STUDY; EMBRYO; FEMALE; FIBROBLAST; FOCAL ADHESION; HEREDITARY NONPOLYPOSIS COLORECTAL CANCER; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; MOUSE; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPORADIC COLON CANCER; WESTERN BLOTTING;

ACTINS; ANIMALS; CARCINOMA; CELL MIGRATION ASSAYS; COLON; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; FEMALE; FIBROBLASTS; HUMANS; LIM-HOMEODOMAIN PROTEINS; LYMPHATIC METASTASIS; MALE; MICE; MIDDLE AGED; MUSCLE PROTEINS; NEOPLASM INVASIVENESS; TRANSCRIPTION FACTORS; TRANSFORMING GROWTH FACTOR BETA1;

EID: 82355181388     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2011.109     Document Type: Article

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