The effects of hormone replacement therapy on hypothalamic neuropeptide gene expression in a primate model of menopause

Journal of Clinical Endocrinology and Metabolism

Volumn 84, Issue 6, 1999, Pages 2111-2118

  Abel, Ty W ^a   Voytko, Mary Lou ^b   Rance, Naomi E ^a,b  

^a UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^b WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NEUROKININ B; NEUROPEPTIDE; PROOPIOMELANOCORTIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HORMONE SUBSTITUTION; MENOPAUSE; MONKEY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALIA; MACACA FASCICULARIS; MAMMALIA; PRIMATES;

EID: 0033304525     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.84.6.2111     Document Type: Article

References (83)

1. Hormone replacement therapy: The need for reconsideration
2. Menopause and hormone replacement therapy
3. Effects of estrogen on memory function in surgically menopausal women
4. Postmenopausal estrogen replacement therapy and the risk of Alzheimer's Disease: A population-based case-control study
5. Hormonal treatment of postmenopausal women
6. Hormone replacement therapy: Management of common problems
7. The subventricular nucleus of the human hypothalamus
8. Post-menopausal hypertrophy of neurons expressing the estrogen receptor gene in the human hypothalamus
9. Hypertrophy and increased gene expression of neurons containing neurokinin-B and substance-P messenger ribonucleic acids in the hypothalami of postmenopausal women
10. Gonadotropin-releasing hormone gene expression is increased in the medial basal hypothalamus of postmenopausal women
11. Proopiomelanocortin (POMC) gene expression is decreased in the hypothalamus of postmenopausal women
12. Effect of sex steroids on β-endorphin in hypophyseal portal blood
13. Behavioural effects of opioid peptides
14. Brain opiates and neuroendocrine function
15. The hypothalamic control of the menstrual cycle and the role of endogenous opioid peptides
16. Endogenous opioid peptides and human reproduction
17. Complete nucleotide sequence of the human corticotropin-β-lipotropin precursor gene
18. Peptide modulation of inflammatory processes within the brain
19. Obesity, diabetes and functions for proopiomelanocortin-derived peptides
20. Role of melanocortinergic neurons in feeding and the agouti obesity syndrome
21. Targeted disruption of the melanocortin-4 receptor results in obesity in mice
22. Ovarian and steroidal influences on neuroendocrine aging processes in female rodents
23. Estrogen-induced hypothalamic beta-endorphin neuron loss: A possible model of hypothalamic aging
24. Effects of long term androgen and estradiol exposure on the hypothalamus
25. Regression of atherosclerosis in female monkeys
26. Medroxyprogesterone acetate antagonizes inhibitory effects of conjugated equine estrogens on coronary artery atherosclerosis
27. Testosterone regulates proopiomelanocortin gene expression in the primate brain
28. Opioid precursor gene expression in the human hypothalamus
29. Localization of neurons expressing substance P and neurokinin B gene transcripts in the human hypothalamus and basal forebrain
30. Anatomical relationship between opioid peptides and receptors in rhesus monkey brain
31. Immunohistochemical detection of progestin receptors in hypothalamic β-endorphin and substance P neurons of steroid-treated monkeys
32. Proopiomelanocortin peptide immunocytochemistry in rhesus monkey brain
33. Distribution of immunoreactive substance P neurons in the hypothalamus and pituitary of the rhesus monkey
34. Esterases in human leukocytes
35. Monocyte-specific esterase isoenzyme demonstrated by isoelectric focusing
36. Inhibitor studies of purified haemopoietic (myeloid) cell esterases. Evidence for the existence of distinct enzyme species
37. Cytochemical markers for mononuclear phagocytes as demonstrated in reactive microglia and globoid cells
38. Light and electron microscopic demonstration of non-specific esterase in amoeboid microglial cells in the corpus callosum in postnatal rats: A cytochemical link to monocytes
39. Novel monocyte-like properties of microglial/astroglial cells. Constitutive secretion of lysozyme and cystatin-C
40. Basic fibroblast growth factor modulates in vitro differentiation of human fetal microglia
41. Fibronectin and laminin regulate the in vitro differentiation of microglial cells
42. Microglia
43. General pathology of neurons and neuroglia
44. Quantitative study of the non-circularity of myelinated peripheral nerve fibres in the cat
45. A useful programme in BASIC for axonal morphometry with introduction of new cytoskeletal parameters
46. Estradiol is selectively neurotoxic to hypothalamic beta-endorphin neurons
47. Neurokinin B gene expression is increased in the arcuate nucleus of ovariectomized rats
48. Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain
49. Immunophenotypic evidence for distinct populations of microglia in the rat hypothalamo-neurohypophysial system
50. Reproductive patterns of three species of macaques
51. Cyclicity and gestation length of Macaca fascicularis
52. The reproductive cycle in female macaques
53. Steroid hormones and the ovarian cycle
54. Menopause in rhesus monkeys: Model for study of disorders in the human climacteric
55. Serum gonadotropin responses to estrogen and progestogen in recently castrated human females
56. Regulation of human gonadotropins. XIII. Changes in serum gonadotropins in menstruating women in response to oophorectomy
57. Endocrine changes and symptomatology after oophorectomy in premenopausal women
58. A primate model of human postmenopausal hot flushes
59. Effects of parenteral administration of estrogen and androgen on plasma hormone levels and hot flushes in the surgical menopause
60. Temperature changes suggestive of hot flushes in rhesus monkeys: Preliminary observations
61. Continuous estrogen decreases neurokinin B expression in the rat arcuate nucleus
62. Sex steroid modulation of neurokinin B gene expression in the arcuate nucleus of adult male rat
63. Presence of nuclear androgen receptor-like immunoreactivity in neurokinin B-containing neurons of the hypothalamic arcuate nucleus of the adult male rat
64. Estrogen concentration by substance P-immunoreactive neurons in the medial basal hypothalamus of the female rat
65. Transcriptional repression of the ovine follicle-stimulating hormone-β gene expression by 17β-estradiol
66. Mechanisms of trans-synaptic regulation of gene expression
67. Neuroendocrine gene expression in the hypothalamus: In situ hybridization histochemical studies
68. Transcriptional analysis of tyrosine hydroxylase gene expression in the tuberoinfundibular dopaminergic neurons of the rat arcuate nucleus after estrogen treatment
69. Neuropeptide gene expression and neural activity: Assessing a working hypothesis in nucleus caudalis and dorsal horn neurons expressing preproenkephalin and preprodynorphin
70. Rapid increase in LHRH mRNA levels following NMDA
71. Unexpected responses of the hypothalamic gonadotropin-releasing hormone 'pulse generator' to physiological estradiol inputs in the absence of the ovary
72. Ovarian control of gonadotropin hormone-releasing hormone pulse generator activity in the rhesus monkey: Duration of the associated hypothalamic signal
73. Estradiol and the inhibition of hypothalamic gonadotropin-releasing hormone pulse generator activity in the rhesus monkey
74. Hypothalamic localization of multiunit electrical activity associated with pulsatile LH release in the rhesus monkey
75. Regional specificity of testosterone regulation of proopiomelanocortin gene expression in the arcuate nucleus of the male rat brain
76. Regulation of proopiomelanocortin messenger ribonucleic acid content by sex steroids in the arcuate nucleus of the female rat brain
77. Gonadal steroid hormone regulation of proopiomelanocortin gene expression in arcuate neurons that innervate the medial preoptic area of the rat
78. Projection of pro-opiomelanocortin neurons from the rat arcuate nucleus to the midbrain central gray as demonstrated by double staining with retrograde labeling and immunohistochemistry
79. Estradiol-induced adult anovulatory syndrome in female C57BL/6J mice: Age-like neuroendocrine, but not ovarian, impairments
80. Oral administration of estradiol to young C57BL/6J mice induces age-like neuroendocrine dysfunctions in the regulation of estrous cycles
81. Effects of a single injection of estradiol valerate on the hypothalamic arcuate nucleus and on reproductive function in the female rat
82. Ovary-dependent degeneration in the hypothalamic arcuate nucleus