Pretreatment with pentoxifylline attenuates lung injury induced by intestinal ischemia/reperfusion in rats;Pré-tratamento com pentoxifilina atenua a lesão pulmonar induzida por isquemia/reperfusão intestinal em ratos

Acta Cirurgica Brasileira

Volumn 26, Issue 6, 2011, Pages 438-444

  Marqui, Carlos Eduardo ^a   Silva, Helga Cristina Almeida ^a   Ferez, David ^a   Cavassani, Sâmia Santos ^a   Moraes, Juliana Britto ^a   da Silva, Danielle Aparecida Marino ^a   Simões, Ricardo Santos ^a   Lopes, Caroline Aparecida ^a   Taha, Murched Omar ^a   Oliveira Jr , Itamar Souza ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Ischemia; Lung Injury; Oxidative Stress; Pentoxifylline; Rats; Reperfusion Injury

Indexed keywords

MYELOPEROXIDASE; PENTOXIFYLLINE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG SCREENING; ENZYME ACTIVITY; INTESTINE ISCHEMIA; LIPID PEROXIDATION; LUNG INJURY; LUNG PROTECTION; LUNG WEIGHT; MALE; NONHUMAN; PROTECTION; RAT; REPERFUSION INJURY; TISSUE LEVEL;

ANIMALS; FREE RADICAL SCAVENGERS; INTESTINES; LUNG INJURY; MALE; PENTOXIFYLLINE; RATS; RATS, WISTAR; REPERFUSION INJURY;

EID: 82355161213     PISSN: 01028650     EISSN: 16782674     Source Type: Journal    
DOI: 10.1590/S0102-86502011000600006     Document Type: Article

References (39)

1. Schoenberg MH, Beger HG. Oxygen radicals in intestinal ischemia and reperfusion. Chem Biol Interact. 1990;76:141-61.
2. Köksoy C, Kuzu MA, Kuzu I, Ergun H, Gurhan I. Role of tumour necrosis factor in lung injury caused by intestinal ischaemiareperfusion. Br J Surg. 2001;88:464-8.
3. Souza DG, Cara DC, Cassali GD, Coutinho SF, Silveira MR, Andrade SP, Poole SP, Teixeira MM. Effects of the PAF receptor antagonist UK74505 on local and remote reperfusion injuries following ischaemia of the superior mesenteric artery in the rat. Br J Pharmacol. 2000;131:1800-8.
4. Hassoun HT, Kone BC, Mercer DW, Moody FG, Weisbrodt NW, Moore FA. Post-injury multiple organ failure: the role of the gut. Shock. 2001;15:1-10.
5. Pierro A, Eaton S. Intestinal ischemia reperfusion injury and multisystem organ failure. Semin Pediatr Surg. 2004;13:11-7.
6. Mallick IH, Yang W, Winslet MC, Seifalian AM. Ischemiareperfusion injury of the intestine and protective strategies against injury. Dig Dis Sci. 2004;49:1359-77.
7. Aytekin FO, Tekin K, Kabay B, Erdem E, Guney Y, Firat P, Sungurtekin U, Kaya SO, Ozden A. Antithrombin III attenuates pulmonary tissue injury caused by mesenteric ischemia-reperfusion. Am J Surg. 2005;189:161-6.
8. Kalia N, Brown NJ, Wood RF, Hopkinson K, Fairburn B, Pockley AG. Effects of intestinal ischemia-reperfusion injury on rat peripheral blood neutrophil activation. Dig Dis Sci. 2003;48:1677-4.
9. Kozar RA, Holcomb JB, Hassoun HT, Macaitis J, DeSoignie R, Moore FA. Superior mesenteric artery occlusion models shockinduced gut ischemia-reperfusion. J Surg Res. 2004;116:145-50.
10. Stallion A, Kou TD, Latifi SQ, Miller KA, Dahms BB, Dudgeon DL, Levine AD. Ischemia/reperfusion: a clinically relevant model of intestinal injury yielding systemic inflammation. J Pediatr Surg. 2005;40:470-7.
11. Steinberg J, Halter J, Schiller H, Gatto L, Nieman G. The development of acute respiratory distress syndrome after gut ischemia/reperfusion injury followed by fecal peritonitis in pigs: a clinically relevant model. Shock. 2005;23:129-37.
12. Ward DT, Lawson SA, Gallagher CM, Conner WC, Shea-Donohue T. Sustained nitric oxide production via l-arginine administration ameliorates effects of intestinal ischemia-reperfusion. J Surg Res. 2000;89:13-9.
13. Grotz MR, Deitch EA, Ding J, Xu D, Huang Q, Regel G. Intestinal cytokine response after gut ischemia: Role of gut barrier failure. Ann Surg. 1999;229:478-86.
14. Bessler H, Gilgal R, Djaldetti M, Zahavi I. Effect of pentoxifylline on the phagocytic activity, cAMP levels, and superoxide anion production by monocytes and polymorphonuclear cells. J Leukocyte Biol. 1986;40:747-54.
15. Mandel GL. ARDS, neutrophils and pentoxifylline. Am Rev Respir Dis. 1988;138:1103-5.
16. Chapelier A, Reignier J, Mazmanian M, Detruit H, Dartevelle P, Parquin F, Cerrina J, Le Roy Ladurie F, Hervé P. Pentoxifylline and lung ischemia-reperfusion injury: Application to lung transplantation. Universite Paris-Sud Lung Transplant Group. J Cardiovasc Pharmacol. 1995;25:S130-3.
17. Seekamp A, Warren JS, Remick DG, Till GO, Ward PA. Requirements for tumor necrosis factor and interleukin-1 in limb ischemia/reperfusion injury and associated lung injury. Am J Pathol. 1993;143:453-63.
18. Lucchesi RR. Complement, neutrophils and free radicals mediators of reperfusion injury. Arzneimittelforschung. 1994;44:420-32.
19. Aslan A, Karaguzel G, Celik M, Uysal N, Yucel G, Melikoglu M. Pentoxifylline contributes to the hepatic cytoprotective process in rats undergoing hepatic ischemia and reperfusion injury. Eur Surg Res. 2001;33:285-90.
20. Iwamoto H, Kozaki N, Nakamura K, Hama K, Narumi N, Matsuno N, Kuzuoka K, Taira S, Kihara Y, Uchiyama M, Takeuchi H, Nagao T. Beneficial effects of pentoxifylline and propentoxifylline on the warm ischemic injury of rat livers. Transplant Proc. 2002;34:2677-8.
21. Oliveira-Júnior IS, Maganhin CC, Carbonel AA, Monteiro CM, Cavassani SS, Oliveira-Filho RM. Effects of pentoxifylline on TNFalpha and lung histopathology in HCL-induced lung injury. Clinics. 2008;63:77-84.
22. Freire Cerqueira N, Hussni CA, Bonetti Yoshida W, Lopes Sequeira J, Padovani CR. Effects of pentoxifylline and n-acetylcysteine on injuries caused by ischemia and reperfusion of splanchnic organs in rats. Int Angiol. 2008;27:512-21.
23. Campos T, Deree J, Martins JO, Loomis WH, Shenvi E, Putnam JG, Coimbra R. Pentoxifylline attenuates pulmonary inflammation and neutrophil activation in experimental acute pancreatitis. Pancreas. 2008;37:42-9.
24. Oliveira-Júnior IS, Oliveira WR, Cavassani SS, Brunialti MK, Salomao R. Effects of pentoxifylline on inflammation and lung dysfunction in ventilated septic animals. J Trauma. 2010;68:822-6.
25. Cavriani G, Domingos HV, Soares AL, Trezena AG, Ligeiro-Oliveira AP, Oliveira-Filho RM, Sudo-Hayashi LS, Tavares de Lima W. Lymphatic system as a path underlying the spread of lung and gut injury after intestinal ischemia/reperfusion in rats. Shock. 2005;23:330-6.
26. Hammerman C, Goldschmidt D, Caplan MS, Kaplan M, Schimmel MS, Eidelman AI, Branski D, Hochman A. Amelioration of ischemia-reperfusion injury in rat intestine by pentoxifyllinemediated inhibition of xanthine oxidase. J Pediatr Gastroenterol Nutr. 1999;29:69-74.
27. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem. 1951;193:265-75.
28. Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem. 1979;95:351-8.
29. Chu SJ, Perng WC, Hung CM, Chang DM, Lin SH, Huang KL. Effects of various body temperatures after lipopolysaccharideinduced lung injury in rats. Chest. 2005;128:327-36.
30. de Perrot M, Liu M, Waddell TK, Keshavjee S. Ischemia-reperfusioninduced lung injury. Am J Respir Crit Care Med. 2003;167:490-511.
31. Granger DN. Role of xanthine oxidase and granulocytes in ischemia-reperfusion injury. Am J Physiol Heart Circ Physiol. 1988;255:H1269-75.
32. Adkins WK, Taylor AE. Role of xanthine oxidase and neutrophils in ischemia-reperfusion injury in rabbit lung. J Appl Physiol. 1990;69:2012-8.
33. Sener G, Akgün U, Satiroǧlu H, Topaloǧlu U, Keyer-Uysal M. The effect of pentoxifylline on intestinal ischemia/reperfusion injury. Fundam Clin Pharmacol. 2001;15:19-22.
34. Pascher A, Klupp J. Biologics in the treatment of transplant rejection and ischemia/reperfusion injury: New applications for TNFα inhibitors? BioDrugs. 2005;19:211-31.
35. Esposito E, Cuzzocrea S. TNF-alpha as a therapeutic target in inflammatory diseases, ischemia-reperfusion injury and trauma. Curr Med Chem. 2009;16:3152-67.
36. Cámara-Lemarroy CR, Guzmán-de la Garza FJ, Alarcón-Galván G, Cordero-Pérez P, Muñoz-Espinosa LE, Fernández-Garza NE. Effects of thalidomide and pentoxyphylline over local and remote organ injury after intestinal ischemia/reperfusion. Transplant Proc. 2010;42:1624-6.
37. Strieter RM, Remick DG, Ward PA, Spengler RN, Lynch III JP, Larrick J, Kunkel SL. Cellular and molecular regulation of tumor necrosis factor-alpha production by pentoxifylline. Biochem Biophys Res Com. 1988;155:1230-6.
38. Orfanos SE, Mavrommati I, Korovesi I, Roussos C. Pulmonary endothelium in acute lung injury: from basic science to the critically ill. Intensive Care Med. 2004;30:1702-14.
39. Puneet P, Moochhala S, Bhatia M. Chemokines in acute respiratory distress syndrome. Am J Physiol Lung Cell Mol Physiol. 2005;288:L3-15.