Synthesis and evaluation of inhibitors of bacterial drug efflux pumps of the major facilitator superfamily

Bioorganic and Medicinal Chemistry

Volumn 19, Issue 24, 2011, Pages 7679-7689

  Okandeji, Babajide O ^a   Greenwald, Daniel M ^a   Wroten, Jessica ^a   Sello, Jason K ^a  

^a BROWN UNIVERSITY   (United States)

Author keywords

Antibacterial; C capped dipeptide; Chloramphenicol; Drug efflux; Efflux pump inhibitor; Multidrug resistance; Streptomyces

Indexed keywords

CHLORAMPHENICOL; DIPEPTIDE DERIVATIVE; MC 2595; MC 4124; ORNITHINE DERIVATIVE; PHENYLALANYLARGININE 2 NAPHTHYLAMIDE; PHENYLARGININE 2 NAPHTHYLAMIDE; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ARTICLE; CHEMICAL REACTION; CONTROLLED STUDY; DRUG POTENTIATION; DRUG SYNTHESIS; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PROTEIN FAMILY; STREPTOMYCES COELICOLOR;

ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; CHLORAMPHENICOL; DIPEPTIDES; DRUG RESISTANCE, MULTIPLE, BACTERIAL; HUMANS; MEMBRANE TRANSPORT PROTEINS; STREPTOMYCES COELICOLOR; STRUCTURE-ACTIVITY RELATIONSHIP;

BACTERIA (MICROORGANISMS); MYCOBACTERIUM TUBERCULOSIS; NEGIBACTERIA; POSIBACTERIA; STREPTOMYCES; STREPTOMYCES COELICOLOR;

EID: 82255183072     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2011.10.011     Document Type: Article

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