Efficient derivation of functional hepatocytes from mouse induced pluripotent stem cells by a combination of cytokines and sodium butyrate

Chinese Medical Journal

Volumn 124, Issue 22, 2011, Pages 3786-3793

  Zhang, Qi ^a   Yang, Yang ^b   Zhang, Jian ^b   Wang, Guo Ying ^b   Liu, Wei ^a   Qiu, Dong Bo ^a   Hei, Zi Qing ^b   Ying, Qi Long ^c   Chen, Gui Hua ^b  

^a Guangdong Provincial Key Laboratory of Liver Disease   (China)

^b THE THIRD AFFILIATED HOSPITAL OF SUN YAT SEN UNIVERSITY   (China)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Cytokines; Differentiation; Embryonic stem cells; Hepatocytes; Induced pluripotent stem cells

Indexed keywords

ACTIVIN A; ALBUMIN; ALKALINE PHOSPHATASE; ALPHA FETOPROTEIN; BETA TUBULIN; BETAIII TUBULIN; BONE MORPHOGENETIC PROTEIN 4; BUTYRIC ACID; CHOLESTEROL 7ALPHA MONOOXYGENASE; CYTOKINE; DIMETHYL SULFOXIDE; INDOCYANINE GREEN; MYOSIN; OCTAMER TRANSCRIPTION FACTOR 4; STAGE SPECIFIC EMBRYO ANTIGEN 1; TRANSCRIPTION FACTOR GATA 4; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG; UREA;

ALBUMIN GENE; ALPHA FETOPROTEIN GENE; ANIMAL CELL; ARTICLE; CARBOHYDRATE METABOLISM; CELL DIFFERENTIATION; CELL FUNCTION; CELL POPULATION; CELL SECRETION; CELL TRANSPORT; CONTROLLED STUDY; CULTURE MEDIUM; CYP7A1 GENE; ECTODERM; EMBRYONIC STEM CELL; GENE; GENE EXPRESSION; GLYCOGEN STORAGE; IN VITRO STUDY; LIVER CELL; MESODERM; MONOLAYER CULTURE; MOUSE; NONHUMAN; OCT3 GENE; PLURIPOTENT STEM CELL; PROTEIN EXPRESSION; SOX2 GENE; UREA CYCLE;

ANIMALS; BUTYRATES; CELL DIFFERENTIATION; CELLS, CULTURED; CYTOKINES; EMBRYONIC STEM CELLS; HEPATOCYTES; INDUCED PLURIPOTENT STEM CELLS; MICE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 82255169402     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0366-6999.2011.22.033     Document Type: Article

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