Cesarean section and interferon-induced helicase gene polymorphisms combine to increase childhood type 1 diabetes risk

Diabetes

Volumn 60, Issue 12, 2011, Pages 3300-3306

  Bonifacio, Ezio ^a,b   Warncke, Katharina ^b,c   Winkler, Christiane ^d   Wallner, Maike ^c   Ziegler, Anette G ^b,c,d  

^a DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^b Forschergruppe Diabetes eV   (Germany)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^d INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; HELICASE; HLA DQA1 ANTIGEN; HLA DQB1 ANTIGEN; HLA DR ANTIGEN; INTERFERON; INTERLEUKIN 2 RECEPTOR ALPHA; ISLET AUTOANTIBODY; UNCLASSIFIED DRUG;

ARTICLE; CESAREAN SECTION; CHILDHOOD DISEASE; CONTROLLED STUDY; DNA POLYMORPHISM; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENOTYPE; HLA SYSTEM; HUMAN; IMMUNE RESPONSE; INSULIN DEPENDENT DIABETES MELLITUS; PANCREAS ISLET; PREGNANCY DIABETES MELLITUS; PRIORITY JOURNAL; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM;

AUTOANTIBODIES; CESAREAN SECTION; DEAD-BOX RNA HELICASES; DIABETES MELLITUS, TYPE 1; DNA HELICASES; FEMALE; HUMANS; INFANT, NEWBORN; INTERFERONS; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; POLYMORPHISM, GENETIC; PREGNANCY; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 22; RISK FACTORS;

EID: 82255164604     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db11-0729     Document Type: Article

References (31)

1. Ziegler AG, Nepom GT. Prediction and pathogenesis in type 1 diabetes. Immunity 2010;32:468-478
2. Patterson CC, Dahlquist GG, Gyürüs E, Green A, Soltész G; EURODIAB Study Group. Incidence trends for childhood type 1 diabetes in Europe during 1989-2003 and predicted new cases 2005-20: a multicentre prospective registration study. Lancet 2009;373:2027-2033
3. Notzon FC, Placek PJ, Taffel SM. Comparisons of national cesarean-section rates. N Engl J Med 1987;316:386-389 (Pubitemid 17034264)
4. Cardwell CR, Stene LC, Joner G, et al. Caesarean section is associated with an increased risk of childhood-onset type 1 diabetes mellitus: a meta-analysis of observational studies. Diabetologia 2008;51:726-735
5. Huurre A, Kalliomäki M, Rautava S, Rinne M, Salminen S, Isolauri E. Mode of delivery: effects on gut microbiota and humoral immunity. Neonatology 2008;93:236-240 (Pubitemid 351799101)
6. Wen L, Ley RE, Volchkov PY, et al. Innate immunity and intestinal microbiota in the development of type 1 diabetes. Nature 2008;455:1109-1113
7. Todd JA. Etiology of type 1 diabetes. Immunity 2010;32:457-467
8. Ziegler AG, Pflueger M, Winkler C, et al. Accelerated progression from islet autoimmunity to diabetes is causing the escalating incidence of type 1 diabetes in young children. J Autoimmun 2011;37:3-7
9. Winkler C, Lauber C, Adler K, et al. An interferon-induced helicase (IFIH1) gene polymorphism associates with different rates of progression from autoimmunity to type 1 diabetes. Diabetes 2011;60:685-690
10. Ziegler AG, Hummel M, Schenker M, Bonifacio E. Autoantibody appearance and risk for development of childhood diabetes in offspring of parents with type 1 diabetes: the 2-year analysis of the German BABYDIAB Study. Diabetes 1999;48:460-468 (Pubitemid 29106857)
11. Achenbach P, Lampasona V, Landherr U, et al. Autoantibodies to zinc transporter 8 and SLC30A8 genotype stratify type 1 diabetes risk. Diabetologia 2009;52:1881-1888
12. Törn C, Mueller PW, Schlosser M, Bonifacio E, Bingley PJ. Diabetes Antibody Standardization Program: evaluation of assays for autoantibodies to glutamic acid decarboxylase and islet antigen-2. Diabetologia 2008;51:846-852
13. Schlosser M, Mueller PW, Törn C, Bonifacio E, Bingley PJ. Diabetes Antibody Standardization Program: evaluation of assays for insulin autoantibodies. Diabetologia 2010;53:2611-2620
14. Schenker M, Hummel M, Ferber K, et al. Early expression and high prevalence of islet autoantibodies for DR3/4 heterozygous and DR4/4 homozygous offspring of parents with type I diabetes: the German BABYDIAB study. Diabetologia 1999;42:671-677 (Pubitemid 29265584)
15. TEDDY Study Group. The Environmental Determinants of Diabetes in the Young (TEDDY) study: study design. Pediatr Diabetes 2007;8:286-298
16. Winkler C, Illig T, Koczwara K, Bonifacio E, Ziegler AG. HHEX-IDE polymorphism is associated with low birth weight in offspring with a family history of type 1 diabetes. J Clin Endocrinol Metab 2009;94:4113-4115
17. Bonifacio E, Hummel M, Walter M, Schmid S, Ziegler AG. IDDM1 and multiple family history of type 1 diabetes combine to identify neonates at high risk for type 1 diabetes. Diabetes Care 2004;27:2695-2700 (Pubitemid 39441472)
18. Algert CS, McElduff A, Morris JM, Roberts CL. Perinatal risk factors for early onset of type 1 diabetes in a 2000-2005 birth cohort. Diabet Med 2009;26:1193-1197
19. Patterson CC, Carson DJ, Hadden DR, Waugh NR, Cole SK. A case-control investigation of perinatal risk factors for childhood IDDM in Northern Ireland and Scotland. Diabetes Care 1994;17:376-381 (Pubitemid 24145210)
20. . McKinney PA, Parslow R, Gurney K, Law G, Bodansky HJ, Williams DR. Antenatal risk factors for childhood diabetes mellitus; a case-control study of medical record data in Yorkshire, UK. Diabetologia 1997;40:933-939 (Pubitemid 27316574)
21. Bragg F, Cromwell DA, Edozien LC, et al. Variation in rates of caesarean section among English NHS trusts after accounting for maternal and clinical risk: cross sectional study. BMJ 2010;341:c5065
22. Warram JH, Krolewski AS, Gottlieb MS, Kahn CR. Differences in risk of insulin-dependent diabetes in offspring of diabetic mothers and diabetic fathers. N Engl J Med 1984;311:149-152 (Pubitemid 14092904)
23. Bonifacio E, Pflüger M, Marienfeld S, Winkler C, Hummel M, Ziegler AG. Maternal type 1 diabetes reduces the risk of islet autoantibodies: relationships with birthweight and maternal HbA(1c). Diabetologia 2008;51:1245-1252
24. Lipponen K, Gombos Z, Kiviniemi M, et al. Effect of HLA class I and class II alleles on progression from autoantibody positivity to overt type 1 diabetes in children with risk-associated class II genotypes. Diabetes 2010;59:3253-3256
25. Barker JM, Barriga KJ, Yu L, et al. Prediction of autoantibody positivity and progression to type 1 diabetes: Diabetes Autoimmunity Study in the Young (DAISY). J Clin Endocrinol Metab 2004;89:3896-3902 (Pubitemid 39071491)
26. von Herrath M. Diabetes: A virus-gene collaboration. Nature 2009;459:518-519
27. Eizirik DL, Colli ML, Ortis F. The role of inflammation in insulitis and beta-cell loss in type 1 diabetes. Nat Rev Endocrinol 2009;5:219-226
28. Giongo A, Gano KA, Crabb DB, et al. Toward defining the autoimmune microbiome for type 1 diabetes. ISME J 2011;5:82-91
29. Gale EA. A missing link in the hygiene hypothesis? Diabetologia 2002;45:588-594
30. Stene LC, Oikarinen S, Hyöty H, et al. Enterovirus infection and progression from islet autoimmunity to type 1 diabetes: the Diabetes and Autoimmunity Study in the Young (DAISY). Diabetes 2010;59:3174-3180
31. Serreze DV, Ottendorfer EW, Ellis TM, Gauntt CJ, Atkinson MA. Acceleration of type 1 diabetes by a coxsackievirus infection requires a preexisting critical mass of autoreactive T-cells in pancreatic islets. Diabetes 2000;49:708-711 (Pubitemid 30339984)