Caesarean section is associated with an increased risk of childhood-onset type 1 diabetes mellitus: A meta-analysis of observational studies

Diabetologia

Volumn 51, Issue 5, 2008, Pages 726-735

  Cardwell, C R ^a   Stene, L C ^b,c   Joner, G ^c,d   Cinek, O ^e   Svensson, J ^f   Goldacre, M J ^g   Parslow, R C ^h   Pozzilli, P ⁱ   Brigis, G ^j   Stoyanov, D ^k   Urbonaite B ^l   Sipetic S ^m   Schober, E ⁿ   Ionescu Tirgoviste, C ^o   Devoti, G ^p   De Beaufort, C E ^q   Buschard, K ^r   Patterson, C C ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^b NORWEGIAN INSTITUTE OF PUBLIC HEALTH   (Norway)

^c ULLEVÅL UNIVERSITY HOSPITAL   (Norway)

^d UNIVERSITY OF OSLO   (Norway)

^e CHARLES UNIVERSITY   (Czech Republic)

^f STENO DIABETES CENTER   (Denmark)

^g UNIVERSITY OF OXFORD   (United Kingdom)

^h UNIVERSITY OF LEEDS   (United Kingdom)

ⁱ UNIVERSITY CAMPUS BIO MEDICO   (Italy)

^j RIGA STRADINS UNIVERSITY   (Latvia)

^k Children's Diabetic Centre Sofia   (Bulgaria)

^l KAUNAS UNIVERSITY OF MEDICINE   (Lithuania)

^m UNIVERSITY OF BELGRADE   (Serbia)

ⁿ MEDICAL UNIVERSITY OF VIENNA   (Austria)

^o Nutrition and Metabolic Diseases 'N Paulescu'   (Romania)

^p UNIVERSITY OF SALENTO   (Italy)

^q DCCP Clinique pédiatrique de Luxembourg   (Luxembourg)

^r Rigshospitalet   (Denmark)

more..

Author keywords

Caesarean section; Cesarean section; Diabetes mellitus; Epidemiology; Type 1

Indexed keywords

ARTICLE; BIRTH WEIGHT; BREAST FEEDING; CESAREAN SECTION; GESTATIONAL AGE; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; MATERNAL AGE; MATERNAL DIABETES MELLITUS; PRIORITY JOURNAL; RISK FACTOR;

EID: 41849111273     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-008-0941-z     Document Type: Article

References (51)

1. Field LL (2002) Genetic linkage and association studies of type I diabetes: challenges and rewards. Diabetologia 45:21-35
2. Green A, Patterson CC (2001) Trends in the incidence of childhood-onset diabetes in Europe 1989-1998. Diabetologia 44(Suppl 3):B3-B8
3. Onkamo P, Vaananen S, Karvonen M, Tuomilehto J (1999) Worldwide increase in incidence of type I diabetes-the analysis of the data on published incidence trends. Diabetologia 42:1395-1403
4. Thomas J, Paranjothy S, Royal College of Obstetricians and Gynaecologists Clinical Effectiveness Support Unit (2007) National sentinel caesarean section audit report. RCOG Press, London
5. Notzon FC, Placek PJ, Taffel SM (1987) Comparisons of national Cesarean-section rates. N Engl J Med 316:386-389
6. Wilberz S, Partke HJ, Dagnaes-Hansen F, Herberg L (1991) Persistent MHV (mouse hepatitis virus) infection reduces the incidence of diabetes mellitus in non-obese diabetic mice. Diabetologia 34:2-5
7. Like AA, Guberski DL, Butler L (1991) Influence of environmental viral agents on frequency and tempo of diabetes mellitus in BB/Wor rats. Diabetes 40:259-262
8. Grönlund MM, Nuutila J, Pelto L et al (1999) Mode of delivery directs the phagocyte functions of infants for the first 6 months of life. Clin Exp Immunol 116:521-526
9. Grönlund MM, Lehtonen OP, Eerola E, Kero P (1999) Fecal microflora in healthy infants born by different methods of delivery: permanent changes in intestinal flora after Cesarean delivery. J Pediatr Gastroenterol Nutr 28:19-25
10. Salminen S, Gibson GR, McCartney AL, Isolauri E (2004) Influence of mode of delivery on gut microbiota composition in seven year old children. Gut 53:1388-1389
11. Penders J, Thijs C, Vink C et al (2006) Factors influencing the composition of the intestinal microbiota in early infancy. Pediatrics 118:511-521
12. Blettner M, Sauerbrei W, Schlehofer B, Scheuchenpflug T, Friedenreich C (1999) Traditional reviews, meta-analyses and pooled analyses in epidemiology. Int J Epidemiol 28:1-9
13. Stene LC, Magnus P, Lie RT, Søvik O, Joner G, The Norwegian Childhood Diabetes Study Group (2001) Maternal and paternal age at delivery, birth order, and risk of childhood onset type 1 diabetes: population based cohort study. BMJ 323:369
14. Sadauskaitė-Kuehne V, Ludvigsson J, Padaiga Z, Jaš inskienė E, Samuelsson U (2004) Longer breastfeeding is an independent protective factor against development of type 1 diabetes mellitus in childhood. Diabetes Metab Res Rev 20:150-157
15. Dahlquist G, Patterson C, Soltész G (1999) Perinatal risk factors for childhood type 1 diabetes in Europe. The EURODIAB Substudy 2 Study Group. Diabetes Care 22:1698-1702
16. Kirkwood BR, Sterne JAC (2003) Essential medical statistics. Blackwell Science, Oxford, p 243
17. Stene LC, Magnus P, Lie RT, Søvik O, Joner G, The Norwegian Childhood Diabetes Study Group (2003) No association between preeclampsia or Cesarean section and incidence of type 1 diabetes among children: a large, population-based cohort study. Pediatr Res 54:487-490
18. Ievins R, Roberts SE, Goldacre MJ (2007) Perinatal factors associated with subsequent diabetes mellitus in the child: record linkage study. Diabet Med 24:664-670
19. Dersimonian R, Laird N (1986) Meta-analysis in clinical-trials. Controlled Clinical Trials 7:177-188
20. Higgins JP, Thompson SG, Deeks JJ, Altman DG (2003) Measuring inconsistency in meta-analyses. Br Med J 327:557-560
21. Sterne JAC, Egger M (2001) Funnel plots for detecting bias in meta-analysis: guidelines on choice of axis. J Clin Epidemiol 54:1046-1055
22. Stukel TA, Demidenko E, Dykes J, Karagas MR (2001) Two-stage methods for the analysis of pooled data. Stat Med 20:2115-2130
23. Duval S, Tweedie R (2000) Trim and fill: a simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis. Biometrics 56:455-463
24. Patterson CC, Carson DJ, Hadden DR, Waugh NR, Cole SK (1994) A case-control investigation of perinatal risk factors for childhood IDDM in Northern Ireland and Scotland. Diabetes Care 17:376-381
25. McKinney PA, Parslow R, Gurney K, Law G, Bodansky HJ, Williams DR (1997) Antenatal risk factors for childhood diabetes mellitus; a case-control study of medical record data in Yorkshire, UK. Diabetologia 40:933-939
26. McKinney PA, Parslow R, Gurney KA, Law GR, Bodansky HJ, Williams R (1999) Perinatal and neonatal determinants of childhood type 1 diabetes. A case-control study in Yorkshire, U.K. Diabetes Care 22:928-932
27. Rami B, Schneider U, Imhof A, Waldhor T, Schober E (1999) Risk factors for type I diabetes mellitus in children in Austria. Eur J Pediatr 158:362-366
28. McKinney PA, Okasha M, Parslow RC et al (2000) Early social mixing and childhood type 1 diabetes mellitus: a case-control study in Yorkshire, UK. Diabet Med 17:236-242
29. Stene LC, Barriga K, Norris JM et al (2004) Perinatal factors and development of islet autoimmunity in early childhood: the diabetes autoimmunity study in the young. Am J Epidemiol 160:3-10
30. Stene LC, Joner G, The Norwegian Childhood Diabetes Study Group (2004) Atopic disorders and risk of childhood-onset type 1 diabetes in individuals. Clin Exp Allergy 34:201-206
31. Visalli N, Sebastiani L, Adorisio E et al (2000) Caesarean section delivery and vitamin D supplement: risk and protective factors for type 1 diabetes. Diabetologia 43(Suppl 1):369 (Abstract)
32. Cardwell CR, Carson DJ, Patterson CC (2005) Parental age at delivery, birth order, birth weight and gestational age are associated with the risk of childhood type 1 diabetes: a UK regional retrospective cohort study. Diabet Med 22:200-206
33. Soltész G, Jeges S, Dahlquist G et al (1994) Nongenetic risk determinants for type-I (insulin-dependent) diabetes-mellitus in childhood. Acta Paediatr 83:730-735
34. Tai TY, Wang CY, Lin LL, Lee LT, Tsai ST, Chen CJ (1998) A case-control study on risk factors for type 1 diabetes in Taipei City. Diabetes Res Clin Pract 42:197-203
35. Jones ME, Swerdlow AJ, Gill LE, Goldacre MJ (1998) Pre-natal and early life risk factors for childhood onset diabetes mellitus: a record linkage study. Int J Epidemiol 27:444-449
36. Bache I, Bock T, Volund A, Buschard K (1999) Previous maternal abortion, longer gestation, and younger maternal age decrease the risk of type 1 diabetes among male offspring. Diabetes Care 22:1063-1065
37. Svensson J, Carstensen B, Mortensen HB, Borch-Johnsen K (2005) Early childhood risk factors associated with type 1 diabetes-is gender important? Eur J Epidemiol 20:429-434
38. Šipetić SB, Vlajinac HD, Kocev NI, Marinković JM, Radmanović SZ, Bjekić MD (2005) The Belgrade childhood diabetes study: a multivariate analysis of risk determinants for diabetes. Eur J Public Health 15:117-122
39. Malcova H, Sumnik Z, Drevinek P, Venhacova J, Lebl J, Cinek O (2006) Absence of breast-feeding is associated with the risk of type 1 diabetes: a case-control study in a population with rapidly increasing incidence. Eur J Pediatr 165:114-119
40. Tenconi MT, Devoti G, Comelli M et al (2007) Major childhood infectious diseases and other determinants associated with type 1 diabetes: a case-control study. Acta Diabetol 44:14-19
41. Blom L, Dahlquist G, Nyström L, Sandström A, Wall S (1989) The Swedish childhood diabetes study-social and perinatal determinants for diabetes in childhood. Diabetologia 32:7-13
42. Dahlquist G, Källén B (1992) Maternal-child blood group incompatibility and other perinatal events increase the risk for early-onset type 1 (insulin-dependent) diabetes mellitus. Diabetologia 35:671-675
43. Visalli N, Sebastiani L, Adorisio E et al (2003) Environmental risk factors for type 1 diabetes in Rome and province. Arch Dis Child 88:695-698
44. Wadsworth EJK, Shield JPH, Hunt LP, Baum JD (1997) A case-control study of environmental factors associated with diabetes in the under 5s. Diabet Med 14:390-396
45. Cardwell CR, Carson DJ, Patterson CC (2007) Secular trends, disease mapping and ecological analyses of the incidence of childhood onset type 1 diabetes in Northern Ireland, 1989-2003. Diabet Med 24:289-95
46. du Prel JB, Icks A, Grabert M, Holl RW, Giani G, Rosenbauer J (2007) Socioeconomic conditions and type 1 diabetes in childhood in North Rhine-Westphalia, Germany. Diabetologia 50:720-728
47. Hunt KJ, Schuller KL (2007) The increasing prevalence of diabetes in pregnancy. Obstet Gynecol Clin North Am 34:173-199
48. Guarner F, Malagelada JR (2003) Gut flora in health and disease. Lancet 361:512-519
49. Gale EA (2002) A missing link in the hygiene hypothesis? Diabetologia 45:588-594
50. Norris JM, Scott FW (1996) A meta-analysis of infant diet and insulin-dependent diabetes mellitus: do biases play a role? Epidemiology 7:87-92
51. Gerstein HC (1994) Cow's milk exposure and type I diabetes mellitus. A critical overview of the clinical literature. Diabetes Care 17:13-19