Role of mitochondrial NADH kinase and NADPH supply in the respiratory chain activity of Saccharomyces cerevisiae

Acta Biochimica et Biophysica Sinica

Volumn 43, Issue 12, 2011, Pages 989-995

  Shi, Feng ^a   Li, Zhijun ^a   Sun, Mingdi ^a   Li, Yongfu ^a  

^a JIANGNAN UNIVERSITY   (China)

Author keywords

NADH kinase; NADPH supply; Pos5p; Respiratory chain activity; Saccharomyces cerevisiae

Indexed keywords

MITOCHONDRIAL PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; PHOSPHOTRANSFERASE; POS5 PROTEIN, S CEREVISIAE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE; SACCHAROMYCES CEREVISIAE PROTEIN;

ARTICLE; ELECTRON TRANSPORT; ENZYMOLOGY; GENE INACTIVATION; GENETICS; METABOLISM; MUTATION; PHYSIOLOGY; SACCHAROMYCES CEREVISIAE;

ELECTRON TRANSPORT; GENE KNOCKOUT TECHNIQUES; MITOCHONDRIAL PROTEINS; MUTATION; NADP; NADPH DEHYDROGENASE; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); REACTIVE OXYGEN SPECIES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 82255164174     PISSN: 16729145     EISSN: 17457270     Source Type: Journal    
DOI: 10.1093/abbs/gmr092     Document Type: Article

References (30)

1. Garavaglia S, Raffaelli N, Finaurini L, Magni G and Rizzi M. A novel fold revealed by Mycobacterium tuberculosis NAD kinase, a key allosteric enzyme in NADP biosynthesis. J Biol Chem 2004, 279: 40980-40986. (Pubitemid 39287698)
2. Kawai S and Murata K. Structure and function of NAD kinase and NADP phosphatase: key enzymes that regulate the intracellular balance of NAD(H) and NADP(H). Biosci Biotechnol Biochem 2008, 72: 919-930. (Pubitemid 351679349)
3. Shi F, Li YF, Li Y andWang XY. Molecular properties, functions and potential applications of NAD kinases. Acta Biochim Biophys Sin 2009, 41: 351-361.
4. Ziegler M. New functions of a long-known molecule. Emerging roles of NAD in cellular signaling. Eur J Biochem 2000, 267: 1550-1564. (Pubitemid 30165506)
5. Maggio-Hall LA and Escalante-Semerena JC. Alpha-5,6-dimethylbenzimidazole adenine dinucleotide (alpha-DAD), a putative new intermediate of coenzyme B12 biosynthesis in Salmonella typhimurium. Microbiology 2003, 149: 983-990. (Pubitemid 36553367)
6. Starai VJ, Celic I, Cole RN, Boeke JD and Escalante-Semerena JC. Sir2-dependent activation of acetyl-CoA synthetase by deacetylation of active lysine. Science 2002, 298: 2390-2392. (Pubitemid 36014212)
7. Minard KI and McAlister-Henn L. Sources of NADPH in yeast vary with carbon source. J Biol Chem 2005, 280: 39890-39896. (Pubitemid 41779123)
8. Kawai S, Mori S, Suzuki S and Murata K. Molecular cloning and identification of UTR1 of a yeast Saccharomyces cerevisiae as a gene encoding an NAD kinase. FEMS Microbiol Lett 2001, 200: 181-184. (Pubitemid 32566359)
9. Outten CE and Culotta VC. A novel NADH kinase is the mitochondrial source of NADPH in Saccharomyces cerevisiae. EMBO J 2003, 22: 2015-2024. (Pubitemid 36565527)
10. Shi F, Kawai S, Mori S, Kono E and Murata K. Identification of ATP-NADH kinase isozymes and their contribution to supply of NADP(H) in Saccharomyces cerevisiae. FEBS J 2005, 272: 3337-3349. (Pubitemid 40979306)
11. Bieganowski P, Seidle HF, Wojcik M and Brenner C. Synthetic lethal and biochemical analyses of NAD and NADH kinases in Saccharomyces cerevisiae establish separation of cellular functions. J Biol Chem 2006, 281: 22439-22445.
12. Miyagi H, Kawai S and Murata K. Two sources of mitochondrial NADPH in the yeast Saccharomyces cerevisiae. J Biol Chem 2009, 284: 7553-7560.
13. Strand MK, Stuart GR, Longley MJ, Graziewicz MA, Dominick OC and Copeland WC. POS5 gene of Saccharomyces cerevisiae encodes a mitochondrial NADH kinase required for stability of mitochondrial DNA. Eukaryot Cell 2003, 2: 809-820. (Pubitemid 36996726)
14. Jo SH, Son MK, Koh HJ, Lee SM, Song IH, Kim YO and Lee YS, et al. Control of mitochondrial redox balance and cellular defense against oxidative damage by mitochondrial NADP-dependent isocitrate dehydrogenase. J Biol Chem 2001, 276: 16168-16176.
15. Thomas D, Cherest H and Surdin-Kerjan Y. Identification of the structural gene for glucose-6-phosphate dehydrogenase in yeast. Inactivation leads to a nutritional requirement for organic sulfur. EMBO J 1991, 10: 547-553. (Pubitemid 21905507)
16. Shianna KV, Marchuk DA and Strand MK. Genomic characterization of POS5, the Saccharomyces cerevisiae mitochondrial NADH kinase. Mitochondrion 2006, 6: 99-106.
17. De Vries S and Grivell LA. Purification and characterization of a rotenone-insensitive NADH: Q6 oxidoreductase from mitochondria of Saccharomyces cerevisiae. Eur J Biochem 1988, 176: 377-384.
18. Luttik MA, Overkamp KM, Kotter P, de Vries S, yan Dijken JP and Pronk JT. The Saccharomyces cerevisiae NDE1 and NDE2 genes encode separate mitochondrial NADH dehydrogenases catalyzing the oxidation of cytosolic NADH. J Biol Chem 1998, 273: 24529-24534. (Pubitemid 28454948)
19. Wach A, Brachat A, Alberti-Segui C, Rebischung C and Philippsen P. Heterologous HIS3 marker and GFP reporter modules for PCR-targeting in Saccharomyces cerevisiae. Yeast 1997, 13: 1065-1075. (Pubitemid 27368517)
20. Gietz RD and Woods RA. Transformation of yeast by lithium acetate/ single-stranded carrier DNA/polyethylene glycol method. Methods Enzymol 2002, 350: 87-96. (Pubitemid 34619485)
21. Boldogh IR and Pon LA. Purification and subfractionation of mitochondria from the yeast Saccharomyces cerevisiae. Methods Cell Biol 2007, 80: 45-64.
22. Lemaire C and Dujardin G. Preparation of respiratory chain complexes from Saccharomyces cerevisiae wild-type and mutant mitochondria. In: Pflieger D and Rossier J eds. Methods in Molecular Biology, vol. 432: Organelle Proteomics. Totowa, NJ: Humana Press, 2008.
23. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye-binding. Anal Biochem 1976, 72: 248-254.
24. Kirby DM, Thorburn DR, Turnbull DM and Taylor RW. Biochemical assays of respiratory chain complex activity. Methods Cell Biol 2007, 80: 93-119.
25. Machida K, Tanaka T, Fujita K and Taniguchi M. Farnesol-induced generation of reactive oxygen species via indirect inhibition of the mitochondrial electron transport chain in the yeast Saccharomyces cerevisiae. J Bacteriol 1998, 180: 4460-4465. (Pubitemid 28405569)
26. Stuart GR, Humble MM, Strand MK and Copeland WC. Transcriptional response to mitochondrial NADH kinase deficiency in Saccharomyces cerevisiae. Mitochondrion 2009, 9: 211-221.
27. Rahman Q, Abidi P, Afaq F, Schiffmann D, Mossman BT, Kamp DW and Athar M. Glutathione redox system in oxidative lung injury. Crit Rev Toxicol 1999, 29: 543-568.
28. Arner ESJ and Holmgren A. Physiological functions of thioredoxin and thioredoxin reductase. Eur J Biochem 2000, 267: 6102-6109.
29. Imlay JA and Linn S. Toxic DNA damage by hydrogen peroxide through Fenton reaction in vivo and in vitro. Science 1988, 240: 640-642.
30. Pain J, Balamurali MM, Dancis A and Pain D. Mitochondrial NADH kinase, Pos5p, is required for efficient iron-sulfur cluster biogenesis in Saccharomyces cerevisiae. J Biol Chem 2010, 285: 39409-39424.