Up-regulation of TGF-β1 mRNA expression in peripheral blood mononuclear cells of patients with chronic fatigue syndrome

Journal of the Formosan Medical Association

Volumn 110, Issue 11, 2011, Pages 701-704

  Zhang, Hai Ying ^a   Liu, Zhan Dong ^b   Hu, Chao Jun ^a   Wang, De Xin ^b   Zhang, Yong Bo ^b   Li, Yong Zhe ^a  

^a PEKING UNION MEDICAL COLLEGE HOSPITAL   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Chronic fatigue syndrome; Polymerase chain reaction; TGF 1; Transforming growth factor beta 1

Indexed keywords

MESSENGER RNA; RNA; TRANSFORMING GROWTH FACTOR BETA1;

ADULT; ARTICLE; CHRONIC FATIGUE SYNDROME; CONTROLLED STUDY; FEMALE; FLUORESCENCE ANALYSIS; HUMAN; MAJOR CLINICAL STUDY; MALE; PERIPHERAL BLOOD MONONUCLEAR CELL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; UPREGULATION;

ADULT; FATIGUE SYNDROME, CHRONIC; FEMALE; HUMANS; LEUKOCYTES, MONONUCLEAR; MALE; MIDDLE AGED; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR BETA1; UP-REGULATION;

EID: 82255162573     PISSN: None     EISSN: 09296646     Source Type: Journal    
DOI: 10.1016/j.jfma.2011.09.006     Document Type: Article

References (19)

1. Bassi N., Amital D., Amital H., Doria A., Shoenfekld Y. Chronic fatigue syndrome: characteristics and possible causes for its pathogenesis. Isr Med Assoc J 2008, 10:79-82.
2. Kennedy G., Spence V., Underwood C., Belch J.J.F. Increased neutrophil apoptosis in chronic fatigue syndrome. J Clin Pathol 2004, 57:891-893.
3. Moss R.B., Mercandetti A., Vojdani A. TNF-alpha and chronic fatigue syndrome. J Clin Immunol 1999, 19:314-316.
4. Robson-Ansley P.J., de Milander L., Collins M., Noakes T.D. Acute interleukin-6 administration impairs athletic performance in healthy, trained male runners. Can J Appl Physiol 2004, 29:411-418.
5. Zheng S.G. The critical role of TGF-beta 1 in the development of induced foxp3+ regulatory T cells. Int J Clin Exp Med 2008, 1:192-202.
6. Miyazono K., Kusanagi K., Inoue H. Divergence and convergence of TGF-beta/BMP signaling. J Cell Physiol 2001, 187:265-276.
7. Roberts A.B., Anzano M.A., Lamb L.C., Smith J.M., Sporn M.B. New class of transforming growth factors potentiated by epidermal growth factor: isolation from non-neoplastic tissues. Proc Natl Acad Sci USA 1981, 78:5339-5343.
8. Gold L.I. The role for transforming growth factor-beta (TGF-beta) in human cancer. Crit Rev Oncog 1999, 10:303-360.
9. Chao C.C., Delahunt M., Hu S., Close K., Peterson P.K. Immunologically mediated fatigue: a murine model. Clin Immunol Immunopathol 1992, 64:161-165.
10. Tomoda A., Joudoi T., Rabab el-M., Matsumoto T., Park T.H., Miike T. Cytokine production and modulation: comparison of patients with chronic fatigue syndrome and normal controls. Psychiatry Res 2005, 134:101-104.
11. Fukuda K., Straus S.E., Hickie I., Sharpe M.C., Dobbins J.G., Komaroff A. The chronic fatigue syndrome: a comprehensive approach to its definition and study. Ann Intern Med 1994, 121:953-959.
12. Robertson M.J., Schacterle R.S., Mackin G.A., Wilson S.N., Bloomingdale K.L., Ritz J. Lymphocyte subset differences in patientswith chronic fatigue syndrome, multiple sclerosis and major depression. Clin Exp Immunol 2005, 141:326-332.
13. Schuster N., Krieglatein K. Mechanisms of TGF-β-mediated apoptosis. Tissue Res 2002, 307:1-4.
14. Chen W.F. Medical immunology 2001, People's Medical Publishing House, Beijing, China, p. 48.
15. Bennett A.L., Chao C.C., Hu S., Buchwald D., Fagioli L.R., Schur P.H. Elevation of bioactive transforming growth factor-beta in serum from patients with chronic fatigue syndrome. J Clin Immunol 1997, 17:160-166.
16. Matsumura S., Shibakusa T., Fujikawa T., Yamada H., Matsumura K., Inoue K. Increase in transforming growth factor-beta in the brain during infection is related to fever, not depression of spontaneous motor activity. Neuroscience 2007, 144:1133-1140.
17. Skowera A., Cleare A., Blair D., Bevis L., Wessely S.C., Peakman M. High levels of type 2 cytokine-producing cells in chronic fatigue syndrome. Clin Exp Immunol 2004, 135:294-302.
18. Yoshikawa M., Hishikawa K., Idei M., Fujita T. Trichostatin a prevents TGF-beta1-induced apoptosis by inhibiting ERK activation in human renal rubular epithelial cells. Eur J Pharmacol 2010, 642:28-36.
19. Sanchez-Capelo A. Dual role for TGF-β in apoptosis. Cytokine Growth Factor Rev 2005, 16:15-34.