Strategies for venous thromboembolism prophylaxis programs

Postgraduate Medicine

Volumn 123, Issue 6, 2011, Pages 91-101

  Lenchus, Joshua D ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

Anticoagulation; Prophylaxis; Risk assessment; Venous thromboembolism

Indexed keywords

ANTIVITAMIN K; FONDAPARINUX; HEPARIN; LOW MOLECULAR WEIGHT HEPARIN;

ANTICOAGULANT THERAPY; ARTICLE; CLINICAL DECISION MAKING; COMPUTERIZED PROVIDER ORDER ENTRY; DECISION SUPPORT SYSTEM; DEEP VEIN THROMBOSIS; EVIDENCE BASED PRACTICE; HOSPITAL ADMISSION; HOSPITAL PATIENT; HUMAN; LENGTH OF STAY; LOW DRUG DOSE; LUNG EMBOLISM; PATIENT CARE; PATIENT COUNSELING; PHARMACIST; PRACTICE GUIDELINE; PRESCRIPTION; PROGNOSIS; REIMBURSEMENT; RISK ASSESSMENT; RISK REDUCTION; SCORING SYSTEM; SURGICAL PATIENT; THROMBOSIS PREVENTION; TOTAL QUALITY MANAGEMENT; UNITED STATES; VENOUS THROMBOEMBOLISM;

ANTICOAGULANTS; CONTINUITY OF PATIENT CARE; HOSPITALIZATION; HUMANS; PATIENT CARE TEAM; PRACTICE GUIDELINES AS TOPIC; PROFESSIONAL ROLE; VENOUS THROMBOEMBOLISM;

EID: 82155192775     PISSN: 00325481     EISSN: 19419260     Source Type: Journal    
DOI: 10.3810/pgm.2011.11.2499     Document Type: Article

References (86)

1. Anderson FA Jr, Zayaruzny M, Heit JA, Fidan D, Cohen AT. Estimated annual numbers of US acute-care hospital patients at risk for venous thromboembolism. Am J Hematol. 2007;82(9):777-782.
2. Geerts WH, Bergqvist D, Pineo GF, et al. Prevention of venous thromboembolism: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest. 2008;133(6 suppl): 381S-453S.
3. Spencer FA, Gore JM, Lessard D, Douketis JD, Emery C, Goldberg RJ. Patient outcomes after deep vein thrombosis and pulmonary embolism: the Worcester Venous Thromboembolism Study. Arch Intern Med. 2008;168(4):425-430.
4. Heit JA. Venous thromboembolism: disease burden, outcomes and risk factors. J Thromb Haemost. 2005;3(8):1611-1617.
5. Stein PD, Beemath A, Olson RE. Trends in the incidence of pulmonary embolism and deep venous thrombosis in hospitalized patients. Am J Cardiol. 2005;95(12):1525-1526.
6. Ruppert A, Steinle T, Lees M. Economic burden of venous thromboembolism: a systematic review. J Med Econ. 2011;14(1):65-74.
7. Vats V, Nutescu EA, Theobald JC, Wojtynek JE, Schumock GT. Survey of hospitals for guidelines, policies, and protocols for anticoagulants. Am J Health Syst Pharm. 2007;64(11):1203-1208.
8. Burleigh E, Wang C, Foster D, et al. Thromboprophylaxis in medically ill patients at risk for venous thromboembolism. Am J Health Syst Pharm. 2006;63(20 suppl 6):S23-S29.
9. Amin AN, Stemkowski S, Lin J, Yang G. Inpatient thromboprophylaxis use in U.S. hospitals: adherence to the seventh American College of Chest Physician's recommendations for at-risk medical and surgical patients. J Hosp Med. 2009;4(8):E15-E21.
10. Cohen AT, Tapson VF, Bergmann JF, et al; ENDORSE Investigators. Venous thromboembolism risk and prophylaxis in the acute hospital care setting (ENDORSE study): a multinational cross-sectional study. Lancet. 2008;371(9610):387-394.
11. Tapson VF, Decousus H, Pini M, et al. Venous thromboembolism prophylaxis in acutely ill hospitalized medical patients: findings from the International Medical Prevention Registry on Venous Thromboembolism. Chest. 2007;132(3):936-945.
12. Spencer FA, Lessard D, Emery C, Reed G, Goldberg RJ. Venous thromboembolism in the outpatient setting. Arch Intern Med. 2007;167(14):1471-1475.
13. Kearon C, Kahn SR, Agnelli G, Goldhaber S, Raskob GE, Comerota AJ; American College of Chest Physicians. Antithrombotic therapy for venous thromboembolic disease: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest. 2008;133(6 suppl):454S-545S.
14. Albers GW, Amarenco P, Easton JD, Sacco RL, Teal P; American College of Chest Physicians. Antithrombotic and thrombolytic therapy for ischemic stroke: American College of Chest Physicians Evidence- Based Clinical Practice Guidelines (8th Edition). Chest. 2008;133 (6 suppl):630S-669S.
15. Guyatt GH, Cook DJ, Jaeschke R, Pauker SG, Schünemann HJ. Grades of recommendation for antithrombotic agents: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest. 2008;133(6 suppl):123S-131S.
16. Drake K. SCIP core measures: Deep impact. Nurs Manage. 2011;42(5): 24-30.
17. The Joint Commission. Specifications Manual for National Hospital Inpatient Quality Measures (version 3.2). http://www.jointcommission.org/specifications_manual_for_national_hospital_inpatient_quality_measures. Accessed July 28, 2011.
18. The Leapfrog Group. The Leapfrog Hospital Survey. What's new in the 2011 survey (version 5.3). https://www.leapfroghospitalsurvey.org/survey_downloads/final.pdf. Accessed June 20, 2011.
19. Groce JB 3rd. Translating evidence-based guidelines into performance measures for venous thromboembolism and acute coronary syndrome. Am J Health Syst Pharm. 2007;64(11 suppl 7):S25-S29.
20. Epstein AM. Pay for performance at the tipping point. N Engl J Med. 2007;356(15):515-517.
21. Lindenauer PK, Remus D, Roman S, et al. Public reporting and pay for performance in hospital quality improvement. N Engl J Med. 2007;356(5):486-496.
22. US Department of Health and Human Services. Centers for Medicare and Medicaid Services. Physician quality reporting system. https://www.cms.gov/pqri/. Accessed July 28, 2011.
23. US Department of Health and Human Services. Centers for Medicare and Medicaid Services. Hospital-acquired conditions. http://www.cms.gov/HospitalAcqCond/06_Hospital-Acquired_Conditions.asp. Accessed July 28, 2011.
24. Sutedjo JL, Ng RK, Piazza G, Goldhaber SZ. Medicare's new regulations for deep vein thrombosis as a "never event": wise or worrisome? Am J Med. 2009;122(11):975-976.
25. Stinnett JM, Pendleton R, Skordos L, Wheeler M, Rodgers GM. Venous thromboembolism prophylaxis in medically ill patients and the development of strategies to improve prophylaxis rates. Am J Hematol. 2005;78(3):167-172.
26. Cohn SL, Adekile A, Mahabir V. Improved use of thromboprophylaxis for deep vein thrombosis following an educational intervention. J Hosp Med. 2006;1(6):331-338.
27. Baskin C, Seetharamu N, Mazure B, et al. Effect of a CD-ROMbased educational intervention on resident knowledge and adherence to deep venous thrombosis prophylaxis guidelines. J Hosp Med. 2008;3(1):42-47.
28. Williams HR, Macdonald DA. Audit of thromboembolic prophylaxis in hip and knee surgery. Ann R Coll Surg Engl. 1997;79(1): 55-57.
29. McEleny P, Bowie P, Robins JB, Brown RC. Getting a validated guideline into local practice: implementation and audit of the SIGN guideline on the prevention of deep vein thrombosis in a district general hospital. Scott Med J. 1998;43(1):23-25.
30. Huang A, Barber N, Northeast A. Deep vein thrombosis prophylaxis protocol-needs active enforcement. Ann R Coll Surg Engl. 2000;82(1): 69-70.
31. Tooher R, Middleton P, Pham C, et al. A systematic review of strategies to improve prophylaxis for venous thromboembolism in hospitals. Ann Surg. 2005;241(3):397-415.
32. Caprini JA, Hyers TM. Compliance with antithrombotic guidelines. Manag Care. 2006;15(9):49-50, 53-60, 66.
33. Scaglione L, Piobbici M, Pagano E, Ballini L, Tamponi G, Ciccone G. Implementing guidelines for venous thromboembolism prophylaxis in a large Italian teaching hospital: lights and shadows. Haematologica. 2005;90(5):678-684.
34. Bullock-Palmer RP, Weiss S, Hyman C. Innovative approaches to increase deep vein thrombosis prophylaxis rate resulting in a decrease in hospital-acquired deep vein thrombosis at a tertiary-care teaching hospital. J Hosp Med. 2008;3(2):148-155.
35. Gilpin VL. Cost savings in quality improvement project to prevent venous thromboembolism. J Vasc Nurs. 2007;25(4):70-74.
36. Sobieraj DM. Development and implementation of a program to assess medical patients' need for venous thromboembolism prophylaxis. Am J Health Syst Pharm. 2008;65(18):1755-1760.
37. Kucher N, Puck M, Blaser J, Bucklar G, Eschmann E, Lüscher TF. Physician compliance with advanced electronic alerts for preventing venous thromboembolism among hospitalized medical patients. J Thromb Haemost. 2009;7(8):1291-1296.
38. Bauer JB, Chun DS, Karpinski TA. Pharmacist-led program to improve venous thromboembolism prophylaxis in a community hospital. Am J Health Syst Pharm. 2008;65(17):1643-1647.
39. Gladding P, Larsen F, Durrant H, Black P. Education together with a preprinted sticker improves the prescribing of prophylactic enoxaparin. N Z Med J. 2007;120(1251):U2461.
40. Kucher N, Koo S, Quiroz R, et al. Electronic alerts to prevent venous thromboembolism among hospitalized patients. N Engl J Med. 2005;352(10):969-977.
41. Lecumberri R, Marqués M, Díaz-Navarlaz MT, et al. Maintained effectiveness of an electronic alert system to prevent venous thromboembolism among hospitalized patients. Thromb Haemost. 2008;100(4):699-704.
42. Caprini JA, Arcelus JI, Reyna JJ. Effective risk stratification of surgical and nonsurgical patients for venous thromboembolic disease. Semin Hematol. 2001;38(2 suppl 5):12-19.
43. Caprini JA. Risk assessment as a guide for the prevention of the many faces of venous thromboembolism. Am J Surg. 2010;199(1 suppl):S3-S10.
44. Maynard GA, Morris TA, Jenkins IH, et al. Optimizing prevention of hospital-acquired venous thromboembolism (VTE): prospective validation of a VTE risk assessment model. J Hosp Med. 2010;5(1):10-18.
45. Spyropoulos AC, Anderson FA, FitzGerald G, Decousus H, Tapson V. Venous thromboembolism risk factors in acutely ill hospitalized medical patients: findings from the IMPROVE registry [abstract]. J Thromb Haemost. 2009;7:122. Abstract OC-MO-052.
46. Durieux P, Nizard R, Ravaud P, Mounier N, Lepage E. A clinical decision support system for prevention of venous thromboembolism: effect on physician behavior. JAMA. 2000;283(21):2816-2821.
47. Society of Hospital Medicine. Venous thromboembolism resource room. http://www.hospitalmedicine.org/ResourceRoomRedesign/RR_VTE/VTE_Home.cfm. Accessed July 28, 2011.
48. Maynard G, Stein J. Preventing hospital-acquired venous thromboembolism: a guide for effective quality improvement. Prepared by the Society of Hospital Medicine. AHRQ publication no. 08-0075. Rockville, MD: Agency for Healthcare Research and Quality. August 2008. http://www.ahrq.gov/qual/vtguide/. Accessed July 28, 2011.
49. Goldhaber SZ, Tapson VF; DVT FREE Steering Committee. A prospective registry of 5,451 patients with ultrasound-confirmed deep-vein thrombosis. Am J Cardiol. 2004;93(2):259-262.
50. Society of Hospital Medicine. SHM hospital-acquired VTE incidence calculator. http://www.hospitalmedicine.org/ResourceRoomRedesign/RR_VTE/PDFs/SHM_Hospital_Acquired_VTE_Incidence_Calculator.xls. Accessed July 28, 2011.
51. Labarere J, Bosson JL, Sevestre MA, Sellier E, Richaud C, Legagneux A. Intervention targeted at nurses to improve venous thromboprophylaxis. Int J Qual Health Care. 2007;19(5):301-308.
52. Dobesh PP, Stacy ZA. Effect of a clinical pharmacy education program on improvement in the quantity and quality of venous thromboembolism prophylaxis for medically ill patients. J Manag Care Pharm. 2005;11(9):755-762.
53. Bond CA, Raehl CL. Pharmacist-provided anticoagulation management in United States hospitals: death rates, length of stay, Medicare charges, bleeding complications, and transfusions. Pharmacotherapy. 2004;24(8): 953-963.
54. Cobaugh DJ, Amin A, Bookwalter T, et al. ASHP-SHM Joint Statement on Hospitalist-Pharmacist Collaboration. Am J Health Syst Pharm. 2008;65(3):260-263.
55. Fitzgerald J. Venous thromboembolism: have we made headway? Orthop Nurs. 2010;29(4):226-234. quiz 235-236.
56. Coffey M, Cornish P, Koonthanam T, Etchells E, Matlow A. Implementation of admission medication reconciliation at two academic health sciences centres: challenges and success factors. Healthc Q. 2009;12:102-109.
57. Heit JA, Silverstein MD, Mohr DN, Petterson TM, O'Fallon WM, Melton LJ 3rd. Risk factors for deep vein thrombosis and pulmonary embolism: a population-based case-control study. Arch Intern Med. 2000;160(6):809-815.
58. Heit JA, O'Fallon WM, Petterson TM, et al. Relative impact of risk factors for deep vein thrombosis and pulmonary embolism: a populationbased study. Arch Intern Med. 2002;162(11):1245-1248.
59. National Institute for Health and Clinical Excellence. Venous thromboembolism: reducing the risk. http://www.nice.org.uk/nicemedia/live/12695/47195/47195.pdf. January 2010. Accessed July 27, 2011.
60. Mittmann N, Knowles S. A survey of Pharmacy and Therapeutic committees across Canada: scope and responsibilities. Can J Clin Pharmacol. 2009;16(1):e171-e177.
61. Scarsi KK, Fotis MA, Noskin GA. Pharmacist participation in medical rounds reduces medication errors. Am J Health Syst Pharm. 2002;59(21): 2089-2092.
62. Kucukarslan SN, Peters M, Mlynarek M, Nafzigar DA. Pharmacists on rounding teams reduce preventable adverse drug events in hospital general medicine units. Arch Intern Med. 2003;163(17):2014-2018.
63. Kaboli PJ, Hoth AB, McClimon BJ, Schnipper JL. Clinical pharmacists and inpatient medical care: a systematic review. Arch Intern Med. 2006;166(9):955-964.
64. Reeder TA, Mutnick A. Pharmacist- versus physician-obtained medication histories. Am J Health Syst Pharm. 2008;65(9):857-860.
65. Makowsky MJ, Schindel TJ, Rosenthal M, Campbell K, Tsuyuki RT, Madill HM. Collaboration between pharmacists, physicians and nurse practitioners: a qualitative investigation of working relationships in the inpatient medical setting. J Interprof Care. 2009;23(2):169-184.
66. Kanter G, Connelly NR, Fitzgerald J. A system and process redesign to improve perioperative antibiotic administration. Anesth Analg. 2006;103(6):1517-1521.
67. Horak B, Hicks K, Pellicciotti S, Duncan A. Create cultural change and team building. Nurs Manage. 2006;37(12):12-14.
68. Carryer J, Gardner G, Dunn S, Gardner A. The core role of the nurse practitioner: practice, professionalism and clinical leadership. J Clin Nurs. 2007;16(10):1818-1825.
69. Bonner L, Cocker E, Wood L. Preventing venous thromboembolism through risk assessment approaches. Br J Nurs. 2008;17(12):778-782.
70. Coleman EA. Falling through the cracks: challenges and opportunities for improving transitional care for persons with continuous complex care needs. J Am Geriatr Soc. 2003;51(4):549-555.
71. Snow V, Beck D, Budnitz T, et al; American College of Physicians; Society of General Internal Medicine; Society of Hospital Medicine, et al. Transitions of Care Consensus Policy Statement American College of Physicians-Society of General Internal Medicine-Society of Hospital Medicine-American Geriatrics Society-American College of Emergency Physicians-Society of Academic Emergency Medicine. J Gen Intern Med. 2009;24(8):971-976.
72. The Care Transitions Program. Care Transitions Measure (CTM). http:// www.caretransitions.org/ctm_main.asp. Accessed July 27, 2011.
73. Kripalani S, Jackson AT, Schnipper JL, Coleman EA. Promoting effective transitions of care at hospital discharge: a review of key issues for hospitalists. J Hosp Med. 2007;2(5):314-323.
74. Phillips CO, Wright SM, Kern DE, Singa RM, Shepperd S, Rubin HR. Comprehensive discharge planning with postdischarge support for older patients with congestive heart failure: a meta-analysis. JAMA. 2004;291(11):1358-1367.
75. Shepperd S, McClaran J, Phillips CO, et al. Discharge planning from hospital to home. Cochrane Database Syst Rev. 2010;(1):CD000313.
76. Kripalani S, LeFevre F, Phillips CO, Williams MV, Basaviah P, Baker DW. Deficits in communication and information transfer between hospital-based and primary care physicians: implications for patient safety and continuity of care. JAMA. 2007;297(8):831-841.
77. Van Walraven C, Laupacis A, Seth R, Wells G. Dictated versus database generated discharge summaries: a randomized clinical trial. CMAJ. 1999;160(3):319-326.
78. Van Walraven C, Seth R, Austin PC, Laupacis A. Effect of discharge summary availability during post-discharge visits on hospital readmission. J Gen Intern Med. 2002;17(3):186-192.
79. Platt AB, Localio AR, Brensinger CM, et al. Risk factors for nonadherence to warfarin: results from the IN-RANGE study. Pharmacoepidemiol Drug Saf. 2008;17(9):853-860.
80. Turner BJ, Hollenbeak C, Weiner MG, et al. Barriers to adherence and hypertension control in a racially diverse representative sample of elderly primary care patients. Pharmacoepidemiol Drug Saf. 2009;18(8):672-681.
81. Colwell CW Jr, Pulido P, Hardwick ME, Morris BA. Patient compliance with outpatient prophylaxis: an observational study. Orthopedics. 2005;28(2):143-147.
82. Taylor NF, Barelli C, Harding KE. Community ambulation before and after hip fracture: a qualitative analysis. Disabil Rehabil. 2010;32(15):1281-1290.
83. Coleman EA, Parry C, Chalmers S, Min SJ. The care transitions intervention: results of a randomized controlled trial. Arch Intern Med. 2006;166(17):1822-1828.
84. The Care Transitions Program. Transition survival skills. http://www. caretransitions.org/transitionskills.asp. Accessed July 27, 2011.
85. Society of Hospital Medicine. BOOSTing care transitions resource Room. http://www.hospitalmedicine.org/ResourceRoomRedesign/RR_CareTransitions/CT_Home.cfm. Accessed July 27, 2011.
86. Map of Medicine. Venous thromboembolism (VTE) risk assessment (all patients). http://eng.mapofmedicine.com/evidence/mapopen/venous_thromboembolism_vte_risk_assessment_and_prophylaxis1.html. Accessed July 27, 2011.