Urokinase induces stromal cell-derived factor-1 expression in human hepatocellular carcinoma cells

Journal of Cellular Physiology

Volumn 227, Issue 2, 2012, Pages 697-704

  Hsu, Wen Hsiu ^a   Chen, Cheng Nan ^b   Huang, Hai I ^c   Lai, Yi Liang ^a   Teng, Chun Yuh ^a   Kuo, Wu Hsien ^a,c,d  

^a TAICHUNG ARMED FORCES GENERAL HOSPITAL   (Taiwan)

^b NATIONAL CHIAYI UNIVERSITY   (Taiwan)

^c CENTRAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^d HUALIEN ARMED FORCES GENERAL HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PREGNANCY SPECIFIC BETA1 GLYCOPROTEIN; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; STROMAL CELL DERIVED FACTOR 1; TRANSCRIPTION FACTOR AP 1; UROKINASE;

ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION;

CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CHEMOKINE CXCL12; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LIVER NEOPLASMS; MAP KINASE KINASE 4; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; RECEPTORS, UROKINASE PLASMINOGEN ACTIVATOR; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; UROKINASE-TYPE PLASMINOGEN ACTIVATOR;

EID: 82155188524     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.22777     Document Type: Article

References (32)

1. Blasi F, Sidenius N. 2010. The urokinase receptor: Focused cell surface proteolysis, cell adhesion and signaling. FEBS Lett 584: 1923-1930.
2. Chiang JK, Sung ML, Yu HR, Chang HI, Kuo HC, Tsai TC, Yen CK, Chen CN. 2011. Homocysteine induces smooth muscle cell proliferation through differential regulation of cyclins A and D1 expression. J Cell Physiol 226: 1017-1026.
3. Chou MT, Chang SN, Ke C, Chang HI, Sung ML, Kuo HC, Chen CN. 2010. The proliferation and differentiation of placental-derived multipotent cells into smooth muscle cells on fibrillar collagen. Biomaterials 31: 4367-4375.
4. Chu H, Zhou H, Liu Y, Liu X, Hu Y, Zhang J. 2007. Functional expression of CXC chemokine recepter-4 mediates the secretion of matrix metalloproteinases from mouse hepatocarcinoma cell lines with different lymphatic metastasis ability. Int J Biochem Cell Biol 39: 197-205.
5. D'Alessio S, Blasi F. 2009. The urokinase receptor as an entertainer of signal transduction. Front Biosci 14: 4575-4587.
6. Gouwy M, Struyf S, Proost P, Van Damme J. 2005. Synergy in cytokine and chemokine networks amplifies the inflammatory response. Cytokine Growth Factor Rev 16: 561-580.
7. Huang F, Geng XP. 2010. Chemokines and hepatocellular carcinoma. World J Gastroenterol 16: 1832-1836.
8. Illemann M, Bird N, Majeed A, Laerum OD, Lund LR, Danø K, Nielsen BS. 2009. Two distinct expression patterns of urokinase, urokinase receptor and plasminogen activator inhibitor-1 in colon cancer liver metastases. Int J Cancer 124: 1860-1870.
9. Itoh T, Hayashi Y, Kanamaru T, Morita Y, Suzuki S, Wang W, Zhou L, Rui JA, Yamamoto M, Kuroda Y, Itoh H. 2000. Clinical significance of urokinase-type plasminogen activator activity in hepatocellular carcinoma. J Gastroenterol Hepatol 15: 422-430.
10. Keeley EC, Mehrad B, Strieter RM. 2010. CXC chemokines in cancer angiogenesis and metastases. Adv Cancer Res 106: 91-111.
11. Keshet Y, Seger R. 2010. The MAP kinase signaling cascades: A system of hundreds of components regulates a diverse array of physiological functions. Methods Mol Biol 661: 3-38.
12. Kopfstein L, Christofori G. 2006. Metastasis: Cell-autonomous mechanisms versus contributions by the tumor microenvironment. Cell Mol Life Sci 63: 449-468.
13. Li W, Gomez E, Zhang Z. 2007. Immunohistochemical expression of stromal cell-derived factor-1 (SDF-1) and CXCR4 ligand receptor system in hepatocellular carcinoma. J Exp Clin Cancer Res 26: 527-533.
14. Liu H, Pan Z, Li A, Fu S, Lei Y, Sun H, Wu M, Zhou W. 2008. Roles of chemokine receptor 4 (CXCR4) and chemokine ligand 12 (CXCL12) in metastasis of hepatocellular carcinoma cells. Cell Mol Immunol 5: 373-378.
15. Mann CD, Neal CP, Garcea G, Manson MM, Dennison AR, Berry DP. 2007. Prognostic molecular markers in hepatocellular carcinoma: A systematic review. Eur J Cancer 43: 979-992.
16. Meijer-van Gelder ME, Look MP, Peters HA, Schmitt M, Brünner N, Harbeck N, Klijn JG, Foekens JA. 2004. Urokinase-type plasminogen activator system in breast cancer: Association with tamoxifen therapy in recurrent disease. Cancer Res 64: 4563-4568.
17. Min L, He B, Hui L. 2011. Mitogen-activated protein kinases in hepatocellular carcinoma development. Semin Cancer Biol 21: 10-20.
18. Moon DO, Kim MO, Choi YH, Kim GY. 2010. Butein sensitizes human hepatoma cells to TRAIL-induced apoptosis via extracellular signal-regulated kinase/Sp1-dependent DR5 upregulation and NF-κB inactivation. Mol Cancer Ther 9: 1583-1595.
19. Murphy PM. 2001. Chemokines and the molecular basis of cancer metastasis. N Engl J Med 345: 833-835.
20. Ou DL, Shen YC, Yu SL, Chen KF, Yeh PY, Fan HH, Feng WC, Wang CT, Lin LI, Hsu C, Cheng AL. 2010. Induction of DNA damage-inducible gene GADD45β contributes to sorafenib-induced apoptosis in hepatocellular carcinoma cells. Cancer Res 70: 9309-9318.
21. Ren Z, Kar S, Wang Z, Wang M, Saavedra JE, Carr BI. 2003. JS-K, a novel non-ionic diazeniumdiolate derivative, inhibits Hep 3B hepatoma cell growth and induces c-Jun phosphorylation via multiple MAP kinase pathways. J Cell Physiol 197: 426-434.
22. Salvi A, Arici B, De Petro G, Barlati S. 2004. Small interfering RNA urokinase silencing inhibits invasion and migration of human hepatocellular carcinoma cells. Mol Cancer Ther 3: 671-678.
23. Seol DW, Chen Q, Zarnegar R. 2000. Transcriptional activation of the hepatocyte growth factor receptor (c-met) gene by its ligand (hepatocyte growth factor) is mediated through AP-1. Oncogene 19: 1132-1137.
24. Severi T, van Malenstein H, Verslype C, van Pelt JF. 2010. Tumor initiation and progression in hepatocellular carcinoma: Risk factors, classification, and therapeutic targets. Acta Pharmacol Sin 31: 1409-1420.
25. Shushakova N, Tkachuk N, Dangers M, Tkachuk S, Park JK, Hashimoto K, Haller H, Dumler I. 2005. Urokinase-induced activation of the gp130/Tyk2/Stat3 pathway mediates a pro-inflammatory effect in human mesangial cells via expression of the anaphylatoxin C5a receptor. J Cell Sci 118: 2743-2753.
26. Smith HW, Marshall CJ. 2010. Regulation of cell signalling by uPAR. Nat Rev Mol Cell Biol 11: 23-36.
27. Sun X, Cheng G, Hao M, Zheng J, Zhou X, Zhang J, Taichman RS, Pienta KJ, Wang J. 2010. CXCL12/CXCR4/CXCR7 chemokine axis and cancer progression. Cancer Metastasis Rev 29: 709-722.
28. Sung ML, Wu CC, Chang HI, Yen CK, Chen HJ, Cheng JC, Chien S, Chen CN. 2009. Shear stress inhibits homocysteine-induced stromal cell-derived factor-1 expression in endothelial cells. Circ Res 105: 755-763.
29. Sutton A, Friand V, Brulé-Donneger S, Chaigneau T, Ziol M, Sainte-Catherine O, Poiré A, Saffar L, Kraemer M, Vassy J, Nahon P, Salzmann JL, Gattegno L, Charnaux N. 2007. Stromal cell-derived factor-1/chemokine (C-X-C motif) ligand 12 stimulates human hepatoma cell growth, migration, and invasion. Mol Cancer Res 5: 21-33.
30. Tang CH, Hill ML, Brumwell AN, Chapman HA, Wei Y. 2008. Signaling through urokinase and urokinase receptor in lung cancer cells requires interactions with β1 integrins. J Cell Sci 121: 3747-3756.
31. Tsai KW, Lai HT, Tsai TC, Wu YC, Yang YT, Chen KY, Chen CM, Li YS, Chen CN. 2009. Difference in the regulation of IL-8 expression induced by uropathogenic E. coli between two kinds of urinary tract epithelial cells. J Biomed Sci 16: 91.
32. Yeh CC, Chang HI, Chiang JK, Tsai WT, Chen LM, Wu CP, Chien S, Chen CN. 2009. Regulation of plasminogen activator inhibitor 1 expression in human osteoarthritic chondrocytes by fluid shear stress: Role of protein kinase Cα. Arthritis Rheum 60: 2350-2361.