Two-dimensional LC-MS fractioning and cross-matching of mass spectrometric data for rational identification of bioactive compounds in crude extracts

Journal of Separation Science

Volumn 34, Issue 23, 2011, Pages 3359-3363

  Klinkenberg, Geir ^a   Sletta, Håvard ^a   Fjærvik, Espen ^b   Zahlsen, Kolbjørn ^a   Bruheim, Per ^a,b  

^a SINTEF MATERIALS AND CHEMISTRY   (Norway)

^b NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

Author keywords

Bioactivity; Bioprospecting; Identification; LC MS

Indexed keywords

BIOACTIVE COMPOUNDS; BIOACTIVE FRACTIONS; BIOLOGICAL COMPOUNDS; BIOLOGICAL EXTRACTS; BIOPROSPECTING; CHROMATOGRAPHIC CONDITIONS; CROSS-MATCHING; CRUDE EXTRACT; LC-MS; MASS DETECTION; MASS SPECTROMETRIC DATA; MASS SPECTROMETRIC DETECTION; NATURAL COMPOUNDS; SCREENING STRATEGY; TWO STAGE; TWO-DIMENSION;

ALGORITHMS; BIOACTIVITY; CHROMATOGRAPHIC ANALYSIS; IDENTIFICATION (CONTROL SYSTEMS); MASS SPECTROMETERS;

SPECTROMETRY;

DACTINOMYCIN; DIMETHYL SULFOXIDE; FUNGAL EXTRACT;

ACTINOBACTERIA; ALGORITHM; ANTIFUNGAL ACTIVITY; ARTICLE; BACTERIUM CULTURE; BACTERIUM ISOLATE; CANDIDA ALBICANS; DRUG IDENTIFICATION; FRACTIONATION; IONIZATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL;

ACTINOBACTERIA; ANTIFUNGAL AGENTS; BIOLOGICAL FACTORS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; MASS SPECTROMETRY;

EID: 82155185336     PISSN: 16159306     EISSN: 16159314     Source Type: Journal    
DOI: 10.1002/jssc.201100468     Document Type: Article

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