Exposure to a complex cocktail of environmental endocrine-disrupting compounds disturbs the kisspeptin/GPR54 system in ovine hypothalamus and pituitary gland

Environmental Health Perspectives

Volumn 117, Issue 10, 2009, Pages 1556-1562

  Bellingham, Michelle ^a   Fowler, Paul A ^b   Amezaga, Maria R ^b   Rhind, Stewart M ^c   Cotinot, Corinne ^d   Mandon Pepin, Beatrice ^d   Sharpe, Richard M ^e   Evans, Neil P ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b UNIVERSITY OF ABERDEEN   (United Kingdom)

^c SCOTTISH CROP RESEARCH INSTITUTE   (United Kingdom)

^d CEMAGREF   (France)

^e UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Environmental chemicals; GPR54; Hypothalamus; Kisspeptin; Pituitary; Prenatal exposure; Sheep

Indexed keywords

ENDOCRINE DISRUPTOR; ESTROGEN RECEPTOR ALPHA; G PROTEIN COUPLED RECEPTOR 54; KISSPEPTIN; LUTEINIZING HORMONE BETA SUBUNIT; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTERIOR HYPOTHALAMUS; ARTICLE; CONTROLLED STUDY; ECOTOXICITY; EWE; FEMALE; FETUS; GENE EXPRESSION; HYPOPHYSIS; HYPOTHALAMUS; NEUROENDOCRINE DISEASE; NONHUMAN; NUCLEOTIDE SEQUENCE; POSTERIOR HYPOTHALAMUS; PRENATAL EXPOSURE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SLUDGE; TISSUE DISTRIBUTION;

ANIMALS; ENDOCRINE DISRUPTORS; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL POLLUTANTS; HYPOTHALAMUS; IMMUNOHISTOCHEMISTRY; PITUITARY GLAND; RECEPTORS, G-PROTEIN-COUPLED; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SHEEP; TUMOR SUPPRESSOR PROTEINS;

ANIMALIA; OVIS; OVIS ARIES;

EID: 70449587210     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.0900699     Document Type: Article

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