Diapocynin and apocynin administration fails to significantly extend survival in G93A SOD1 ALS mice

Neurobiology of Disease

Volumn 45, Issue 1, 2012, Pages 137-144

  Trumbull, Kari A ^a   McAllister, Donna ^b   Gandelman, Mandi M ^a,c   Fung, Whitney Y ^a   Lew, Thomas ^b   Brennan, Lucy ^b   Lopez, Nathan ^b   Morré, Jeff ^d   Kalyanaraman, Balaraman ^b   Beckman, Joseph S ^a,d  

^a OREGON STATE UNIVERSITY   (United States)

^b FREE RADICAL RESEARCH CENTER   (United States)

^c INSTITUT PASTEUR DE MONTEVIDEO   (Uruguay)

^d OREGON STATE UNIVERSITY   (United States)

Author keywords

ALS; Apocynin; Diapocynin; G93A SOD1 mice; NADPH oxidase

Indexed keywords

APOCYNIN; COPPER ZINC SUPEROXIDE DISMUTASE; DIAPOCYNIN; NITRIC OXIDE; OXIDOREDUCTASE INHIBITOR; UNCLASSIFIED DRUG; VANILLIC ACID;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN TISSUE; CENTRAL NERVOUS SYSTEM; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE RESPONSE; DRUG BRAIN LEVEL; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TREATMENT FAILURE; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ION MONITORING; LIFE EXTENSION; MALE; MASS SPECTROMETRY; MOTONEURON; MOUSE; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPINAL CORD; SURVIVAL TIME; TREATMENT DURATION;

ACETOPHENONES; AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; BIPHENYL COMPOUNDS; LONGEVITY; MICE; MICE, NEUROLOGIC MUTANTS; MOTOR NEURONS; RATS; RATS, TRANSGENIC; SUPEROXIDE DISMUTASE; TREATMENT OUTCOME;

EID: 81955168003     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2011.07.015     Document Type: Article

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