Synthesis of an advanced intermediate toward the hNK-1 antagonist with the cyclopentane core

Synlett

Volumn , Issue 19, 2011, Pages 2872-2874

  Nakata, Kenya ^a   Kiyotsuka, Yohei ^a   Kitazume, Tomoya ^a   Kobayashi, Yuichi ^a  

^a TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

copper; cyclopentane; Grignard reaction; hNK 1 antagonist; substitution

Indexed keywords

4 CYCLO PENTENE 1,3 DIOL; ACETIC ACID DERIVATIVE; ALCOHOL; AMINE; COPPER CHLORIDE; CYCLOPENTANE; CYCLOPENTENE DERIVATIVE; EPOXIDE; MONOMETHOXYACETATE; NEUROKININ 1 RECEPTOR ANTAGONIST; NUCLEOPHILE; PHTHALIMIDE; UNCLASSIFIED DRUG;

ALLYLIC REARRANGEMENT; ARTICLE; EPOXIDATION; MITSUNOBU REACTION; REDUCTION; STEREOCHEMISTRY; SYNTHESIS;

EID: 81855207287     PISSN: 09365214     EISSN: 14372096     Source Type: Journal    
DOI: 10.1055/s-0031-1289863     Document Type: Article

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