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note
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2 with aqueous base gave no desired product. See the Supporting Information for catalyst screening details.
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26
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33750083784
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note
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2.
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30
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33750040169
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note
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3N, DIPEA, and KF.
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31
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33750039542
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note
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Other solvents giving poorer conversion, regioselectivity, and/or enantioselectivity were toluene, dioxane, acetonitrile, DMF, methanol, and 2-propanol.
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32
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33750063063
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note
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See the Supporting Information for complete ligands screening.
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33
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