Involvement of different human glutathione transferase isoforms in the glutathione conjugation of reactive metabolites of troglitazone

Drug Metabolism and Disposition

Volumn 39, Issue 12, 2011, Pages 2290-2297

  Okada, Ran ^a   Maeda, Kazuya ^a   Nishiyama, Takahito ^b   Aoyama, Shinsuke ^c   Tozuka, Zenzaburo ^c   Hiratsuka, Akira ^b   Ikeda, Toshihiko ^d   Kusuhara, Hiroyuki ^a   Sugiyama, Yuichi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

^c SEKISUI CHEMICAL CO LTD   (Japan)

^d YOKOHAMA COLLEGE OF PHARMACY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG METABOLITE; GLUTATHIONE; GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE A1; GLUTATHIONE TRANSFERASE A2; GLUTATHIONE TRANSFERASE M1; GLUTATHIONE TRANSFERASE P1; GLUTATHIONE TRANSFERASE T1; QUINONE DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TROGLITAZONE;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CONJUGATION; HUMAN; LIVER MICROSOME; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

CATALYSIS; CHROMANS; CHROMATOGRAPHY, LIQUID; GLUTATHIONE; GLUTATHIONE TRANSFERASE; HUMANS; HYPOGLYCEMIC AGENTS; ISOENZYMES; MICROSOMES, LIVER; MUTATION; TANDEM MASS SPECTROMETRY; THIAZOLIDINEDIONES;

EID: 81855206600     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.111.040469     Document Type: Article

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