메뉴 건너뛰기




Volumn 39, Issue 12, 2011, Pages 2370-2380

Analysis and prediction of drug transfer into human milk taking into consideration secretion and reuptake clearances across the mammary epithelia

Author keywords

[No Author keywords available]

Indexed keywords

ACICLOVIR; ALPRAZOLAM; AMFEBUTAMONE; ATENOLOL; BUDESONIDE; CARBENICILLIN; CEFALOTIN; CEFAPIRIN; CEFOTAXIME; CHLORAMPHENICOL; CIMETIDINE; CLARITHROMYCIN; CLINDAMYCIN; DIGOXIN; DILTIAZEM; DISOPYRAMIDE PHOSPHATE; FLUCONAZOLE; LABETALOL; METFORMIN; METHYLDOPA; METOPROLOL; MOCLOBEMIDE; NITROFURANTOIN; PARACETAMOL; PENICILLIN G POTASSIUM; PROPRANOLOL; TERBUTALINE; THIAMAZOLE; UNINDEXED DRUG; VERAPAMIL;

EID: 81855206580     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.111.040972     Document Type: Article
Times cited : (30)

References (36)
  • 1
    • 0036827601 scopus 로고    scopus 로고
    • Transporter gene expression in lactating and nonlactating human mammary epithelial cells using real-time reverse transcription-polymerase chain reaction
    • DOI 10.1124/jpet.102.038315
    • Alcorn J, Lu X, Moscow JA, and McNamara PJ (2002) Transporter gene expression in lactating and nonlactating human mammary epithelial cells using real-time reverse transcriptionpolymerase chain reaction. J Pharmacol Exp Ther 303:487-496. (Pubitemid 35231217)
    • (2002) Journal of Pharmacology and Experimental Therapeutics , vol.303 , Issue.2 , pp. 487-496
    • Alcorn, J.1    Lu, X.2    Moscow, J.A.3    McNamara, P.J.4
  • 2
    • 0023918182 scopus 로고
    • Prediction of drug concentrations in human skim milk from plasma protein binding and acid-base characteristics
    • Atkinson HC and Begg EJ (1988a) Prediction of drug concentrations in human skim milk from plasma protein binding and acid-base characteristics. Br J Clin Pharmacol 25:495-503.
    • (1988) Br J Clin Pharmacol , vol.25 , pp. 495-503
    • Atkinson, H.C.1    Begg, E.J.2
  • 3
    • 0024209224 scopus 로고
    • Relationship between human milk lipid-ultrafiltrate and octanol-water partition coefficients
    • DOI 10.1002/jps.2600770916
    • Atkinson HC and Begg EJ (1988b) Relationship between human milk lipid-ultrafiltrate and octanol-water partition coefficients. J Pharm Sci 77:796-798. (Pubitemid 19030317)
    • (1988) Journal of Pharmaceutical Sciences , vol.77 , Issue.9 , pp. 796-798
    • Atkinson, H.C.1    Begg, E.J.2
  • 4
    • 0025350095 scopus 로고
    • Prediction of drug distribution into human milk from physicochemical characteristics
    • Atkinson HC and Begg EJ (1990) Prediction of drug distribution into human milk from physicochemical characteristics. Clin Pharmacokinet 18:151-167. (Pubitemid 20104033)
    • (1990) Clinical Pharmacokinetics , vol.18 , Issue.2 , pp. 151-167
    • Atkinson, H.C.1    Begg, E.J.2
  • 5
    • 0028898732 scopus 로고
    • Quantitative structure-activity relationships for skin permeability
    • Barratt MD (1995) Quantitative structure-activity relationships for skin permeability. Toxicol In Vitro 9:27-37.
    • (1995) Toxicol in Vitro , vol.9 , pp. 27-37
    • Barratt, M.D.1
  • 6
    • 0027566681 scopus 로고
    • The short-term synthesis and infant-regulated removal of milk in lactating women
    • Daly SE, Owens RA, and Hartmann PE (1993) The short-term synthesis and infant-regulated removal of milk in lactating women. Exp Physiol 78:209-220.
    • (1993) Exp Physiol , vol.78 , pp. 209-220
    • Daly, S.E.1    Owens, R.A.2    Hartmann, P.E.3
  • 7
    • 0017164024 scopus 로고
    • Breast-feeding protects against respiratory syncytial virus infections
    • Downham MA, Scott R, Sims DG, Webb JK, and Gardner PS (1976) Breast-feeding protects against respiratory syncytial virus infections. Br Med J 2:274-276.
    • (1976) Br Med J , vol.2 , pp. 274-276
    • Downham, M.A.1    Scott, R.2    Sims, D.G.3    Webb, J.K.4    Gardner, P.S.5
  • 8
    • 4344581009 scopus 로고    scopus 로고
    • Influence of parental mental health on early termination of breast-feeding: A case-control study
    • Falceto OG, Giugliani ER, and Fernandes CL (2004) Influence of parental mental health on early termination of breast-feeding: a case-control study. J Am Board Fam Pract 17:173-183.
    • (2004) J Am Board Fam Pract , vol.17 , pp. 173-183
    • Falceto, O.G.1    Giugliani, E.R.2    Fernandes, C.L.3
  • 10
    • 0037472056 scopus 로고    scopus 로고
    • Models and methods for predicting drug transfer into human milk
    • Fleishaker JC (2003) Models and methods for predicting drug transfer into human milk. Adv Drug Deliv Rev 55:643-652.
    • (2003) Adv Drug Deliv Rev , vol.55 , pp. 643-652
    • Fleishaker, J.C.1
  • 11
    • 77949880178 scopus 로고    scopus 로고
    • Lactation stage-dependent expression of transporters in rat whole mammary gland and primary mammary epithelial organoids
    • Gilchrist SE and Alcorn J (2010) Lactation stage-dependent expression of transporters in rat whole mammary gland and primary mammary epithelial organoids. Fundam Clin Pharmacol 24:205-214.
    • (2010) Fundam Clin Pharmacol , vol.24 , pp. 205-214
    • Gilchrist, S.E.1    Alcorn, J.2
  • 13
    • 77049186581 scopus 로고
    • Clinical and chemical studies in human lactation
    • Hytten FE (1954) Clinical and chemical studies in human lactation. Br Med J 1:175-182.
    • (1954) Br Med J , vol.1 , pp. 175-182
    • Hytten, F.E.1
  • 14
    • 0019307524 scopus 로고
    • Composition of the lipids in human milk: A review
    • DOI 10.1007/BF02533550
    • Jensen RG, Clark RM, and Ferris AM (1980) Composition of the lipids in human milk: a review. Lipids 15:345-355. (Pubitemid 10008677)
    • (1980) Lipids , vol.15 , Issue.5 , pp. 345-355
    • Jensen, R.G.1    Clark, R.M.2    Ferris, A.M.3
  • 16
    • 63949085325 scopus 로고    scopus 로고
    • In silico prediction of drug permeability across buccal mucosa
    • Kokate A, Li X, Williams PJ, Singh P, and Jasti BR (2009) In silico prediction of drug permeability across buccal mucosa. Pharm Res 26:1130-1139.
    • (2009) Pharm Res , vol.26 , pp. 1130-1139
    • Kokate, A.1    Li, X.2    Williams, P.J.3    Singh, P.4    Jasti, B.R.5
  • 18
    • 0025831361 scopus 로고
    • Pharmacokinetics of acetaminophen, antipyrine, and salicylic acid in the lactating and nursing rabbit, with model predictions of milk to serum concentration ratios and neonatal dose
    • McNamara PJ, Burgio D, and Yoo SD (1991) Pharmacokinetics of acetaminophen, antipyrine, and salicylic acid in the lactating and nursing rabbit, with model predictions of milk to serum concentration ratios and neonatal dose. Toxicol Appl Pharmacol 109:149-160.
    • (1991) Toxicol Appl Pharmacol , vol.109 , pp. 149-160
    • McNamara, P.J.1    Burgio, D.2    Yoo, S.D.3
  • 19
    • 0026692060 scopus 로고
    • Pharmacokinetics of cimetidine during lactation: Species differences in cimetidine transport into rat and rabbit milk
    • McNamara PJ, Burgio D, and Yoo SD (1992) Pharmacokinetics of cimetidine during lactation: species differences in cimetidine transport into rat and rabbit milk. J Pharmacol Exp Ther 261:918-923.
    • (1992) J Pharmacol Exp Ther , vol.261 , pp. 918-923
    • McNamara, P.J.1    Burgio, D.2    Yoo, S.D.3
  • 20
    • 17844365262 scopus 로고    scopus 로고
    • The breast cancer resistance protein (BCRP/ABCG2) affects pharmacokinetics, hepatobiliary excretion, and milk secretion of the antibiotic nitrofurantoin
    • DOI 10.1124/mol.104.010439
    • Merino G, Jonker JW, Wagenaar E, van Herwaarden AE, and Schinkel AH (2005) The breast cancer resistance protein (BCRP/ABCG2) affects pharmacokinetics, hepatobiliary excretion, and milk secretion of the antibiotic nitrofurantoin. Mol Pharmacol 67:1758-1764. (Pubitemid 40594177)
    • (2005) Molecular Pharmacology , vol.67 , Issue.5 , pp. 1758-1764
    • Merino, G.1    Jonker, J.W.2    Wagenaar, E.3    Van Herwaarden, A.E.4    Schinkel, A.H.5
  • 21
    • 0014108501 scopus 로고
    • Diffusion of certain weak organic acids and bases across the bovine mammary gland membrane after systemic administration
    • Miller GE, Banerjee NC, and Stowe CM Jr (1967) Diffusion of certain weak organic acids and bases across the bovine mammary gland membrane after systemic administration. J Pharmacol Exp Ther 157:245-253.
    • (1967) J Pharmacol Exp Ther , vol.157 , pp. 245-253
    • Miller, G.E.1    Banerjee, N.C.2    Stowe Jr., C.M.3
  • 22
    • 65049087667 scopus 로고    scopus 로고
    • QSAR application for the prediction of compound permeability with in silico descriptors in practical use
    • Nakao K, Fujikawa M, Shimizu R, and Akamatsu M (2009) QSAR application for the prediction of compound permeability with in silico descriptors in practical use. J Comput Aided Mol Des 23:309-319.
    • (2009) J Comput Aided Mol des , vol.23 , pp. 309-319
    • Nakao, K.1    Fujikawa, M.2    Shimizu, R.3    Akamatsu, M.4
  • 25
    • 21044457398 scopus 로고    scopus 로고
    • Anatomy of the lactating human breast redefined with ultrasound imaging
    • DOI 10.1111/j.1469-7580.2005.00417.x
    • Ramsay DT, Kent JC, Hartmann RA, and Hartmann PE (2005) Anatomy of the lactating human breast redefined with ultrasound imaging. J Anat 206:525-534. (Pubitemid 40873207)
    • (2005) Journal of Anatomy , vol.206 , Issue.6 , pp. 525-534
    • Ramsay, D.T.1    Kent, J.C.2    Hartmann, R.A.3    Hartmann, P.E.4
  • 26
    • 0015617666 scopus 로고
    • Drugs in breast milk
    • Rivera-calimlim L (1977) Drugs in breast milk. Drug Ther 7:59-63.
    • (1977) Drug Ther , vol.7 , pp. 59-63
    • Rivera-calimlim, L.1
  • 30
    • 0018942264 scopus 로고
    • Kinetics of theophylline transfer to breast milk
    • Stec GP, Greenberger P, Ruo TI, Henthorn T, Morita Y, Atkinson AJ Jr, and Patterson R (1980) Kinetics of theophylline transfer to breast milk. Clin Pharmacol Ther 28:404-408. (Pubitemid 10007023)
    • (1980) Clinical Pharmacology and Therapeutics , vol.28 , Issue.3 , pp. 404-408
    • Stec, G.P.1    Greenberger, P.2    Ruo, T.I.3
  • 31
    • 0035821601 scopus 로고    scopus 로고
    • Experimental and computational screening models for the prediction of intestinal drug absorption
    • DOI 10.1021/jm001101a
    • Stenberg P, Norinder U, Luthman K, and Artursson P (2001) Experimental and computational screening models for the prediction of intestinal drug absorption. J Med Chem 44:1927-1937. (Pubitemid 32884517)
    • (2001) Journal of Medicinal Chemistry , vol.44 , Issue.12 , pp. 1927-1937
    • Stenberg, P.1    Norinder, U.2    Luthman, K.3    Artursson, P.4
  • 32
    • 30344444454 scopus 로고    scopus 로고
    • The function of breast cancer resistance protein in epithelial barriers, stem cells and milk secretion of drugs and xenotoxins
    • van Herwaarden AE and Schinkel AH (2006) The function of breast cancer resistance protein in epithelial barriers, stem cells and milk secretion of drugs and xenotoxins. Trends Pharmacol Sci 27:10-16.
    • (2006) Trends Pharmacol Sci , vol.27 , pp. 10-16
    • Van Herwaarden, A.E.1    Schinkel, A.H.2
  • 33
    • 0141815941 scopus 로고    scopus 로고
    • Wild-type breast cancer resistance protein (BCRP/ABCG2) is a methotrexate polyglutamate transporter
    • Volk EL and Schneider E (2003) Wild-type breast cancer resistance protein (BCRP/ABCG2) is a methotrexate polyglutamate transporter. Cancer Res 63:5538-5543. (Pubitemid 37139875)
    • (2003) Cancer Research , vol.63 , Issue.17 , pp. 5538-5543
    • Volk, E.L.1    Schneider, E.2
  • 34
    • 57349095219 scopus 로고    scopus 로고
    • N-(4-[2-(1,2,3,4-tetrahydro-6,7-dimethoxy-2-isoquinolinyl)ethyl]-phenyl) -9,10-dihydro-5-methoxy-9-oxo-4-acridine carboxamide (GF120918) as a chemical ATP-binding cassette transporter family G member 2 (Abcg2) knockout model to study nitrofurantoin transfer into milk
    • Wang L, Leggas M, Goswami M, Empey PE, and McNamara PJ (2008) N-(4-[2-(1,2,3,4-tetrahydro-6,7-dimethoxy-2-isoquinolinyl)ethyl]-phenyl)-9, 10-dihydro-5-methoxy-9-oxo-4-acridine carboxamide (GF120918) as a chemical ATP-binding cassette transporter family G member 2 (Abcg2) knockout model to study nitrofurantoin transfer into milk. Drug Metab Dispos 36:2591-2596.
    • (2008) Drug Metab Dispos , vol.36 , pp. 2591-2596
    • Wang, L.1    Leggas, M.2    Goswami, M.3    Empey, P.E.4    McNamara, P.J.5
  • 35
    • 0020956528 scopus 로고
    • Determinants and consequences of drug excretion in breast milk
    • Wilson JT (1983) Determinants and consequences of drug excretion in breast milk. Drug Metab Rev 14:619-652.
    • (1983) Drug Metab Rev , vol.14 , pp. 619-652
    • Wilson, J.T.1
  • 36
    • 0032480901 scopus 로고    scopus 로고
    • Correlation of human jejunal permeability (in vivo) of drugs with experimentally and theoretically derived parameters. A multivariate data analysis approach
    • DOI 10.1021/jm9810102
    • Winiwarter S, Bonham NM, Ax F, Hallberg A, Lennernäs H, and Karlén A (1998) Correlation of human jejunal permeability (in vivo) of drugs with experimentally and theoretically derived parameters. A multivariate data analysis approach. J Med Chem 41:4939-4949. (Pubitemid 28555452)
    • (1998) Journal of Medicinal Chemistry , vol.41 , Issue.25 , pp. 4939-4949
    • Winiwarter, S.1    Bonham, N.M.2    Ax, F.3    Hallberg, A.4    Lennernas, H.5    Karlen, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.