메뉴 건너뛰기




Volumn 32, Issue 12, 2011, Pages 1782-1788

14-3-3σ and p63 play opposing roles in epidermal tumorigenesis

Author keywords

[No Author keywords available]

Indexed keywords

14 3 3SIGMA PROTEIN; 7,12 DIMETHYLBENZ[A]ANTHRACENE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN P63; RAS PROTEIN; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

EID: 81855206510     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgr207     Document Type: Article
Times cited : (13)

References (35)
  • 1
    • 21044434194 scopus 로고    scopus 로고
    • Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer
    • Benzinger,A. et al. (2005) Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer. Mol. Cell. Proteomics., 4, 785-795.
    • (2005) Mol. Cell. Proteomics. , vol.4 , pp. 785-795
    • Benzinger, A.1
  • 2
    • 33644877400 scopus 로고    scopus 로고
    • 14-3-3 proteins: a number of functions for a numbered protein
    • Bridges,D. et al. (2005) 14-3-3 proteins: a number of functions for a numbered protein. Sci. STKE., 296, re10.
    • (2005) Sci. STKE. , vol.296
    • Bridges, D.1
  • 3
    • 33744544172 scopus 로고    scopus 로고
    • 14-3-3 proteins in cell cycle regulation
    • Hermeking,H. et al. (2006) 14-3-3 proteins in cell cycle regulation. Semin. Cancer. Biol., 16, 183-192.
    • (2006) Semin. Cancer. Biol. , vol.16 , pp. 183-192
    • Hermeking, H.1
  • 4
    • 27644529779 scopus 로고    scopus 로고
    • A mutation in stratifin is responsible for the repeated epilation (Er) phenotype in mice
    • Herron,B.J. et al. (2005) A mutation in stratifin is responsible for the repeated epilation (Er) phenotype in mice. Nat. Genet., 37, 1210-1212.
    • (2005) Nat. Genet. , vol.37 , pp. 1210-1212
    • Herron, B.J.1
  • 5
    • 27644525123 scopus 로고    scopus 로고
    • Identification of 14-3-3sigma mutation causing cutaneous abnormality in repeated-epilation mutant mouse
    • Li,Q. et al. (2005) Identification of 14-3-3sigma mutation causing cutaneous abnormality in repeated-epilation mutant mouse. Proc. Natl Acad. Sci. USA, 102, 15977-15982.
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 15977-15982
    • Li, Q.1
  • 6
    • 12944275670 scopus 로고    scopus 로고
    • High frequency of hypermethylation at the 14-3-3 sigma locus leads to gene silencing in breast cancer
    • Ferguson,A.T. et al. (2000) High frequency of hypermethylation at the 14-3-3 sigma locus leads to gene silencing in breast cancer. Proc. Natl Acad. Sci. USA, 97, 6049-6054.
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 6049-6054
    • Ferguson, A.T.1
  • 7
    • 0041834566 scopus 로고    scopus 로고
    • Analysis of 14-3-3 sigma expression in hyperproliferative skin diseases reveals selective loss associated with CpG-methylation in basal cell carcinoma
    • Lodygin,D. et al. (2003) Analysis of 14-3-3 sigma expression in hyperproliferative skin diseases reveals selective loss associated with CpG-methylation in basal cell carcinoma. Oncogene, 22, 5519-5524.
    • (2003) Oncogene , vol.22 , pp. 5519-5524
    • Lodygin, D.1
  • 8
    • 0033533612 scopus 로고    scopus 로고
    • 14-3-3 Sigma is required to prevent mitotic catastrophe after DNA damage
    • Chan,T.A. et al. (1999) 14-3-3 Sigma is required to prevent mitotic catastrophe after DNA damage. Nature, 401, 616-620.
    • (1999) Nature , vol.401 , pp. 616-620
    • Chan, T.A.1
  • 9
    • 0031310665 scopus 로고    scopus 로고
    • 14-3-3 sigma is a p53-regulated inhibitor of G2/ M progression
    • Hermeking,H. et al. (1997) 14-3-3 sigma is a p53-regulated inhibitor of G2/ M progression. Mol. Cell, 1, 3-11.
    • (1997) Mol. Cell , vol.1 , pp. 3-11
    • Hermeking, H.1
  • 10
    • 0033594491 scopus 로고    scopus 로고
    • p63 is a p53 homologue required for limb and epidermal morphogenesis
    • Mills,A.A. et al. (1999) p63 is a p53 homologue required for limb and epidermal morphogenesis. Nature, 398, 708-713.
    • (1999) Nature , vol.398 , pp. 708-713
    • Mills, A.A.1
  • 11
    • 0033594485 scopus 로고    scopus 로고
    • p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development
    • Yang,A. et al. (1999) p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development. Nature, 398, 714-718.
    • (1999) Nature , vol.398 , pp. 714-718
    • Yang, A.1
  • 12
    • 67650461955 scopus 로고    scopus 로고
    • Rescue of key features of the p63-null epithelial phenotype by inactivation of Ink4a and Arf
    • Su,X. et al. (2009) Rescue of key features of the p63-null epithelial phenotype by inactivation of Ink4a and Arf. EMBO J., 28, 1904-1915.
    • (2009) EMBO J , vol.28 , pp. 1904-1915
    • Su, X.1
  • 13
    • 33751230475 scopus 로고    scopus 로고
    • p63 regulates proliferation and differentiation of developmentally mature keratinocytes
    • Truong,A.B. et al. (2006) p63 regulates proliferation and differentiation of developmentally mature keratinocytes. Genes Dev., 20, 3185-3197.
    • (2006) Genes Dev. , vol.20 , pp. 3185-3197
    • Truong, A.B.1
  • 14
    • 0037377761 scopus 로고    scopus 로고
    • The Delta Np63 alpha phosphoprotein binds the p21 and 14-3-3 sigma promoters in vivo and has transcriptional repressor activity that is reduced by Hay-Wells syndrome-derived mutations
    • Westfall,M.D. et al. (2003) The Delta Np63 alpha phosphoprotein binds the p21 and 14-3-3 sigma promoters in vivo and has transcriptional repressor activity that is reduced by Hay-Wells syndrome-derived mutations. Mol. Cell. Biol., 23, 2264-2276.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 2264-2276
    • Westfall, M.D.1
  • 15
    • 17444390129 scopus 로고    scopus 로고
    • Tumor predisposition in mice mutant for p63 and p73: evidence for broader tumor suppressor functions for the p53 family
    • Flores,E.R. et al. (2005) Tumor predisposition in mice mutant for p63 and p73: evidence for broader tumor suppressor functions for the p53 family. Cancer Cell, 7, 363-373.
    • (2005) Cancer Cell , vol.7 , pp. 363-373
    • Flores, E.R.1
  • 16
    • 33744830912 scopus 로고    scopus 로고
    • p63 heterozygous mutant mice are not prone to spontaneous or chemically induced tumors
    • Keyes,W.M. et al. (2006) p63 heterozygous mutant mice are not prone to spontaneous or chemically induced tumors. Proc. Natl Acad. Sci. USA, 103, 8435-8440.
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 8435-8440
    • Keyes, W.M.1
  • 17
    • 79953651072 scopus 로고    scopus 로고
    • IKK1 control of epidermal differentiation is modulated by notch signaling
    • Xin,Y. et al. (2011) IKK1 control of epidermal differentiation is modulated by notch signaling. Am. J. Pathol., 178, 1568-1577.
    • (2011) Am. J. Pathol. , vol.178 , pp. 1568-1577
    • Xin, Y.1
  • 18
    • 34250666701 scopus 로고    scopus 로고
    • Production and purification of lentiviral vectors
    • Tiscornia,G. et al. (2006) Production and purification of lentiviral vectors. Nat. Protoc., 1, 241-245.
    • (2006) Nat. Protoc. , vol.1 , pp. 241-245
    • Tiscornia, G.1
  • 19
    • 43049181659 scopus 로고    scopus 로고
    • Regulation of Dlx5 and Dlx6 gene expression by p63 is involved in EEC and SHFM congenital limb defects
    • Lo Iacono,N. et al. (2008) Regulation of Dlx5 and Dlx6 gene expression by p63 is involved in EEC and SHFM congenital limb defects. Development, 135, 1377-1388.
    • (2008) Development , vol.135 , pp. 1377-1388
    • Lo Iacono, N.1
  • 20
    • 29744445504 scopus 로고    scopus 로고
    • Unique domain functions of p63 isotypes that differentially regulate distinct aspects of epidermal homeostasis
    • King,K.E. et al. (2006) Unique domain functions of p63 isotypes that differentially regulate distinct aspects of epidermal homeostasis. Carcinogenesis, 27, 53-63.
    • (2006) Carcinogenesis , vol.27 , pp. 53-63
    • King, K.E.1
  • 21
    • 76749094583 scopus 로고    scopus 로고
    • 14-3-3sigma controls corneal epithelial cell proliferation and differentiation through the Notch signaling pathway
    • Xin,Y. et al. (2010) 14-3-3sigma controls corneal epithelial cell proliferation and differentiation through the Notch signaling pathway. Biochem. Biophys. Res. Commun., 392, 593-598.
    • (2010) Biochem. Biophys. Res. Commun. , vol.392 , pp. 593-598
    • Xin, Y.1
  • 22
    • 0025244024 scopus 로고
    • Increased sensitivity to two-stage skin carcinogenesis of mice heterozygous for the repeated epilation mutation (Er)
    • Reddy,A.L. et al. (1990) Increased sensitivity to two-stage skin carcinogenesis of mice heterozygous for the repeated epilation mutation (Er). Int. J. Cancer, 46, 928-930.
    • (1990) Int. J. Cancer , vol.46 , pp. 928-930
    • Reddy, A.L.1
  • 23
    • 0034729189 scopus 로고    scopus 로고
    • Downregulation of 14-3-3sigma prevents clonal evolution and leads to immortalization of primary human keratinocytes
    • Dellambra,E. et al. (2000) Downregulation of 14-3-3sigma prevents clonal evolution and leads to immortalization of primary human keratinocytes. J. Cell Biol., 149, 1117-1130.
    • (2000) J. Cell Biol. , vol.149 , pp. 1117-1130
    • Dellambra, E.1
  • 24
    • 0034625043 scopus 로고    scopus 로고
    • AIS is an oncogene amplified in squamous cell carcinoma
    • Hibi,K. et al. (2000) AIS is an oncogene amplified in squamous cell carcinoma. Proc. Natl Acad. Sci. USA, 97, 5462-5467.
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 5462-5467
    • Hibi, K.1
  • 25
    • 19044363045 scopus 로고    scopus 로고
    • DeltaNp63 induces beta-catenin nuclear accumulation and signaling
    • Patturajan,M. et al. (2002) DeltaNp63 induces beta-catenin nuclear accumulation and signaling. Cancer Cell, 1, 369-379.
    • (2002) Cancer Cell , vol.1 , pp. 369-379
    • Patturajan, M.1
  • 26
    • 0034099274 scopus 로고    scopus 로고
    • Frequent gain of the p40/p51/p63 gene locus in primary head and neck squamous cell carcinoma
    • Yamaguchi et al. (2000) Frequent gain of the p40/p51/p63 gene locus in primary head and neck squamous cell carcinoma. Int. J. Cancer, 86, 684-689.
    • (2000) Int. J. Cancer , vol.86 , pp. 684-689
    • Yamaguchi, X.X.1
  • 27
    • 0033372016 scopus 로고    scopus 로고
    • Association of p63 with proliferative potential in normal and neoplastic human keratinocytes
    • Parsa,R. et al. (1999) Association of p63 with proliferative potential in normal and neoplastic human keratinocytes. J. Invest. Dermatol., 113, 1099-1105.
    • (1999) J. Invest. Dermatol. , vol.113 , pp. 1099-1105
    • Parsa, R.1
  • 28
    • 0034255855 scopus 로고    scopus 로고
    • Characterization of the expression pattern of p63 alpha and delta Np63 alpha in benign and malignant oral epithelial lesions
    • Nylander,K. et al. (2000) Characterization of the expression pattern of p63 alpha and delta Np63 alpha in benign and malignant oral epithelial lesions. Int. J. Cancer, 87, 368-372.
    • (2000) Int. J. Cancer , vol.87 , pp. 368-372
    • Nylander, K.1
  • 29
    • 0034234312 scopus 로고    scopus 로고
    • Frequent alteration of p63 expression in human primary bladder carcinomas
    • Park,B.J. et al. (2000) Frequent alteration of p63 expression in human primary bladder carcinomas. Cancer Res., 60, 3370-3374.
    • (2000) Cancer Res , vol.60 , pp. 3370-3374
    • Park, B.J.1
  • 30
    • 0034644195 scopus 로고    scopus 로고
    • High level expression of deltaN-p63: a mechanism for the inactivation of p53 in undifferentiated nasopharyngeal carcinoma (NPC)?
    • Crook,T. et al. (2000) High level expression of deltaN-p63: a mechanism for the inactivation of p53 in undifferentiated nasopharyngeal carcinoma (NPC)? Oncogene, 19, 3439-3444.
    • (2000) Oncogene , vol.19 , pp. 3439-3444
    • Crook, T.1
  • 31
    • 79952747169 scopus 로고    scopus 로고
    • Distinct expression profiles of p63 variants during urothelial development and bladder cancer progression
    • Karni-Schmidt,O. et al. (2011) Distinct expression profiles of p63 variants during urothelial development and bladder cancer progression. Am. J. Pathol., 178, 1350-1360.
    • (2011) Am. J. Pathol. , vol.178 , pp. 1350-1360
    • Karni-Schmidt, O.1
  • 32
    • 0345189361 scopus 로고    scopus 로고
    • Impaired p63 expression associates with poor prognosis and uroplakin III expression in invasive urothelial carcinoma of the bladder
    • Koga,F. et al. (2003) Impaired p63 expression associates with poor prognosis and uroplakin III expression in invasive urothelial carcinoma of the bladder. Clin. Cancer. Res., 9, 5501-5507.
    • (2003) Clin. Cancer. Res. , vol.9 , pp. 5501-5507
    • Koga, F.1
  • 33
    • 13944255793 scopus 로고    scopus 로고
    • RACK1 and stratifin target DeltaNp63alpha for a proteasome degradation in head and neck squamous cell carcinoma cells upon DNA damage
    • Fomenkov,A. et al. (2004) RACK1 and stratifin target DeltaNp63alpha for a proteasome degradation in head and neck squamous cell carcinoma cells upon DNA damage. Cell Cycle, 3, 1285-1295.
    • (2004) Cell Cycle , vol.3 , pp. 1285-1295
    • Fomenkov, A.1
  • 34
    • 72249108928 scopus 로고    scopus 로고
    • p73 and p63 sustain cellular growth by transcriptional activation of cell cycle progression genes
    • Lefkimmiatis,K. et al. (2009) p73 and p63 sustain cellular growth by transcriptional activation of cell cycle progression genes. Cancer Res., 69, 8563-8571.
    • (2009) Cancer Res. , vol.69 , pp. 8563-8571
    • Lefkimmiatis, K.1
  • 35
    • 79551607574 scopus 로고    scopus 로고
    • DeltaNp63alpha is an oncogene that targets chromatin remodeler Lsh to drive skin stem cell proliferation and tumorigenesis
    • Keyes,W.M. et al. (2011) DeltaNp63alpha is an oncogene that targets chromatin remodeler Lsh to drive skin stem cell proliferation and tumorigenesis. Cell Stem Cell, 8, 164-176.
    • (2011) Cell Stem Cell , vol.8 , pp. 164-176
    • Keyes, W.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.