Rapid cancer detection by topically spraying a γ- glutamyltranspeptidase-activated fluorescent probe

Science Translational Medicine

Volumn 3, Issue 110, 2011, Pages

  Urano, Yasuteru ^a,b   Sakabe, Masayo ^c   Kosaka, Nobuyuki ^d   Ogawa, Mikako ^d   Mitsunaga, Makoto ^d   Asanuma, Daisuke ^a   Kamiya, Mako ^a   Young, Matthew R ^e   Nagano, Tetsuo ^c   Choyke, Peter L ^d   Kobayashi, Hisataka ^d  

^a UNIVERSITY OF TOKYO   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d NATIONAL CANCER INSTITUTE   (United States)

^e NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLUORESCENT DYE; GAMMA GLUTAMYLTRANSFERASE; RHODAMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL CULTURE; CANCER DIAGNOSIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME SPECIFICITY; FEMALE; FLUORESCENCE IMAGING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR IMAGING; MOLECULAR PROBE; MOUSE; NONHUMAN; OVARY CANCER; PERITONEUM CANCER; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; ANIMAL; CHEMISTRY; EARLY DIAGNOSIS; METABOLISM; METHODOLOGY; NEOPLASM; PATHOLOGY; SPECTROFLUOROMETRY; TOPICAL DRUG ADMINISTRATION; TUMOR CELL LINE;

ADMINISTRATION, TOPICAL; ANIMALS; CELL LINE, TUMOR; EARLY DETECTION OF CANCER; FEMALE; FLUORESCENT DYES; GAMMA-GLUTAMYLTRANSFERASE; HUMANS; MICE; NEOPLASMS; RHODAMINES; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, FLUORESCENCE;

EID: 81855205302     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.3002823     Document Type: Article

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