메뉴 건너뛰기




Volumn 22, Issue 14, 2008, Pages 1877-1880

Clade-specific HIV-1 integrase polymorphisms do not reduce raltegravir and elvitegravir phenotypic susceptibility

Author keywords

[No Author keywords available]

Indexed keywords

ELVITEGRAVIR; INTEGRASE; RALTEGRAVIR;

EID: 66349126931     PISSN: 02699370     EISSN: 14735571     Source Type: Journal    
DOI: 10.1097/QAD.0b013e32830f9703     Document Type: Article
Times cited : (37)

References (25)
  • 1
    • 0029655459 scopus 로고    scopus 로고
    • Conserved sequences in the carboxyl terminus of integrase that are essential for human immunodeficiency virus type 1 replication
    • Cannon PM, Byles ED, Kingsman SM, Kingsman AJ. Conserved sequences in the carboxyl terminus of integrase that are essential for human immunodeficiency virus type 1 replication. I Virol 1996; 70:651-657.
    • (1996) I Virol , vol.70 , pp. 651-657
    • Cannon, P.M.1    Byles, E.D.2    Kingsman, S.M.3    Kingsman, A.J.4
  • 3
    • 0027456715 scopus 로고    scopus 로고
    • Bushman FD, Engelman A, Palmer I, Wingfield P, Craigie R. Domains of the integrase protein of human immunodeficiency virus type 1 responsible for polynucleotidyl transfer and zinc binding. Proc Natl Acad Sci U S A1 993; 90:3428-3432.
    • Bushman FD, Engelman A, Palmer I, Wingfield P, Craigie R. Domains of the integrase protein of human immunodeficiency virus type 1 responsible for polynucleotidyl transfer and zinc binding. Proc Natl Acad Sci U S A1 993; 90:3428-3432.
  • 4
    • 0026649557 scopus 로고
    • Identification of conserved amino acid residues critical for human immunodeficiency virus type 1 integrase function in vitro
    • Engelman A, Craigie R. Identification of conserved amino acid residues critical for human immunodeficiency virus type 1 integrase function in vitro. J Virol 1992; 66:6361-6369.
    • (1992) J Virol , vol.66 , pp. 6361-6369
    • Engelman, A.1    Craigie, R.2
  • 5
    • 0028067324 scopus 로고
    • The core and carboxyl-terminal domains of the integrase protein of human immunodeficiency virus type 1 each contribute to nonspecific DNA binding
    • Engelman A, Hickman AB, Craigie R. The core and carboxyl-terminal domains of the integrase protein of human immunodeficiency virus type 1 each contribute to nonspecific DNA binding. J Virol 1994; 68:5911 -5917.
    • (1994) J Virol , vol.68 , pp. 5911-5917
    • Engelman, A.1    Hickman, A.B.2    Craigie, R.3
  • 6
    • 0037064049 scopus 로고    scopus 로고
    • DNA-induced polymerization of HIV-1 integrase analyzed with fluorescence fluctuation spectroscopy
    • Vercammen J, Maertens G, Gerard M, De Clercq E, Debyser Z, Engelborghs Y. DNA-induced polymerization of HIV-1 integrase analyzed with fluorescence fluctuation spectroscopy. I Biol Chem 2002; 277:38045-38052.
    • (2002) I Biol Chem , vol.277 , pp. 38045-38052
    • Vercammen, J.1    Maertens, G.2    Gerard, M.3    De Clercq, E.4    Debyser, Z.5    Engelborghs, Y.6
  • 8
    • 37849002059 scopus 로고    scopus 로고
    • Shimura K, Kodama E, Sakagami Y, Matsuzaki Y, Watanabe W, Yamataka K, et al. Broad antiretroviral activity and resistance profile of the novel human immunodeficiency virus integrase inhibitor elvitegravir (JTK-303/GS-9137). J Virol2008; 82:764-774.
    • Shimura K, Kodama E, Sakagami Y, Matsuzaki Y, Watanabe W, Yamataka K, et al. Broad antiretroviral activity and resistance profile of the novel human immunodeficiency virus integrase inhibitor elvitegravir (JTK-303/GS-9137). J Virol2008; 82:764-774.
  • 9
    • 34248177765 scopus 로고    scopus 로고
    • Results of BENCHMRK-1, a Phase III study evaluating the efficacy and safety of MK-0518, a novel HIV-1 integrase inhibitor, in patients with triple-class resistant virus
    • Los Angeles, California
    • Cooper D, Gatell J, Rockstoh J. Results of BENCHMRK-1, a Phase III study evaluating the efficacy and safety of MK-0518, a novel HIV-1 integrase inhibitor, in patients with triple-class resistant virus. In: 14th Conference on Retroviruses and Opportunistic Infections; 2007; Los Angeles, California.
    • (2007) 14th Conference on Retroviruses and Opportunistic Infections
    • Cooper, D.1    Gatell, J.2    Rockstoh, J.3
  • 11
    • 34248205567 scopus 로고    scopus 로고
    • Results of BENCHMRK-1, a Phase III study evaluating the efficacy and safety of MK-0518, a novel HIV-1 integrase inhibitor, in patients with triple-class resistant virus
    • Los Angeles, California
    • Steigbigel R, Kumar P, Eron J. Results of BENCHMRK-1, a Phase III study evaluating the efficacy and safety of MK-0518, a novel HIV-1 integrase inhibitor, in patients with triple-class resistant virus. In: 14th Conference on Retroviruses and Opportunistic Infections; 2007; Los Angeles, California.
    • (2007) 14th Conference on Retroviruses and Opportunistic Infections
    • Steigbigel, R.1    Kumar, P.2    Eron, J.3
  • 13
    • 66349135983 scopus 로고    scopus 로고
    • Van Baelen K, Rondelez E, Van Eygen V, Van den Zegel P, Clynhens M, Vandenbroucke I, Stuyver LJ. Development of a genotypic and phenotypic recombinant virus assay to determine resistance against HIV-1 integrase inhibitors. In: European Society for Clinical Virology; 2008; Lapland, Finland.
    • Van Baelen K, Rondelez E, Van Eygen V, Van den Zegel P, Clynhens M, Vandenbroucke I, Stuyver LJ. Development of a genotypic and phenotypic recombinant virus assay to determine resistance against HIV-1 integrase inhibitors. In: European Society for Clinical Virology; 2008; Lapland, Finland.
  • 14
    • 66249092459 scopus 로고    scopus 로고
    • Novel HIV-1 integrase mutations, found as minority quasispecies in patients naive to integrase inhibitors, are associated with decreased susceptibility to integrase inhibitors in vitro
    • Boston, Massachusetts
    • Ceccherini-Silberstein F, Van Baelen K, Armenia D, Trignetti M, Fabeni L, Rondelez E, et al. Novel HIV-1 integrase mutations, found as minority quasispecies in patients naive to integrase inhibitors, are associated with decreased susceptibility to integrase inhibitors in vitro. In: 1 5th Conferenceon Retroviruses and Opportunistic Infections; 2008; Boston, Massachusetts.
    • (2008) 1 5th Conferenceon Retroviruses and Opportunistic Infections
    • Ceccherini-Silberstein, F.1    Van Baelen, K.2    Armenia, D.3    Trignetti, M.4    Fabeni, L.5    Rondelez, E.6
  • 15
    • 34247202879 scopus 로고    scopus 로고
    • Natural polymorphism of the HIV-1 integrase gene and mutations associated with integrase inhibitor resistance
    • Lataillade M, Chiarella J, Kozal MJ. Natural polymorphism of the HIV-1 integrase gene and mutations associated with integrase inhibitor resistance. Antivir Ther 2007; 11:S28.
    • (2007) Antivir Ther , vol.11
    • Lataillade, M.1    Chiarella, J.2    Kozal, M.J.3
  • 16
    • 48449088969 scopus 로고    scopus 로고
    • Specific mutations related to resistance to HIV-1 integrase inhibitors are associated with reverse tran-scriptase mutations in HAART-treated patients
    • Ceccherini-Silberstein F, Malet I, Fabeni L, Svicher V, Gori C, Dimonte S, et al. Specific mutations related to resistance to HIV-1 integrase inhibitors are associated with reverse tran-scriptase mutations in HAART-treated patients. Antivir Ther 2007; 12:S6.
    • (2007) Antivir Ther , vol.12
    • Ceccherini-Silberstein, F.1    Malet, I.2    Fabeni, L.3    Svicher, V.4    Gori, C.5    Dimonte, S.6
  • 18
    • 34248197441 scopus 로고    scopus 로고
    • Frequency of naturally occuring polymorphisms associated with resistance to integrase inhibitors in a recently infected cohort
    • Los Angeles, California, USA
    • Low A, Mohri H, MarkowitzM. Frequency of naturally occuring polymorphisms associated with resistance to integrase inhibitors in a recently infected cohort. In: 14th Conference on Retroviruses and Opportunistic Infections; 2007; Los Angeles, California, USA.
    • (2007) 14th Conference on Retroviruses and Opportunistic Infections
    • Low, A.1    Mohri, H.2    MarkowitzM3
  • 19
    • 48449088480 scopus 로고    scopus 로고
    • HIV-1 integrase sequence variation and covariation
    • Myers RE, Pillay D. HIV-1 integrase sequence variation and covariation. Antivir Ther 2007; 12:S5.
    • (2007) Antivir Ther , vol.12
    • Myers, R.E.1    Pillay, D.2
  • 20
    • 66349091681 scopus 로고    scopus 로고
    • Genetic diversity of integrase in HIV-1 subtypes B, F, and C, prevalent in Brazil: Study in drug-naive and multidrug-resistant individuals reveals impact for drug resistance
    • Los Angeles, California, USA
    • Passaes C, Guimarães M, Lorete R, Fernandez J, Morgado M. Genetic diversity of integrase in HIV-1 subtypes B, F, and C, prevalent in Brazil: Study in drug-naive and multidrug-resistant individuals reveals impact for drug resistance. In: 14th Conference on Retroviruses and Opportunistic Infections; 2007; Los Angeles, California, USA.
    • (2007) 14th Conference on Retroviruses and Opportunistic Infections
    • Passaes, C.1    Guimarães, M.2    Lorete, R.3    Fernandez, J.4    Morgado, M.5
  • 21
    • 48449104295 scopus 로고    scopus 로고
    • Effects of protease and reverse transcriptase inhibitor-resistance mutations on integrase polymorphism in multidrug resistance cases
    • Suzuki H, Fujino M, Matsuda M, Yen H, Iwantani Y, Sugiura W. Effects of protease and reverse transcriptase inhibitor-resistance mutations on integrase polymorphism in multidrug resistance cases. Antivir Ther 2007; 12:S4.
    • (2007) Antivir Ther , vol.12
    • Suzuki, H.1    Fujino, M.2    Matsuda, M.3    Yen, H.4    Iwantani, Y.5    Sugiura, W.6
  • 24
    • 70350163320 scopus 로고    scopus 로고
    • Identification of residues in HIV-1 integrase, RNAseH and the RT connection domain associated with the presence ofthymidine analogue-associated resistance
    • Budapest, Hungary
    • Van Eygen V, Van Marck H, Smits V, Clynhens M, Rondelez E, Van Baelen K, Stuyver LJ. Identification of residues in HIV-1 integrase, RNAseH and the RT connection domain associated with the presence ofthymidine analogue-associated resistance. In: 6th European HIV Resistance Workshop; 2008; Budapest, Hungary.
    • (2008) 6th European HIV Resistance Workshop
    • Van Eygen, V.1    Van Marck, H.2    Smits, V.3    Clynhens, M.4    Rondelez, E.5    Van Baelen, K.6    Stuyver, L.J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.