Evaluation of new and established age-related macular degeneration susceptibility genes in the Women'S Health Initiative Sight Exam (WHI-SE) study

American Journal of Ophthalmology

Volumn 152, Issue 6, 2011, Pages

  Peter, Inga ^a   Huggins, Gordon S ^b   Ordovas, Jose M ^c   Haan, Mary ^d   Seddon, Johanna M ^b  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c TUFTS UNIVERSITY   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER A1; APOLIPOPROTEIN E; CHOLESTEROL ESTER TRANSFER PROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; TISSUE INHIBITOR OF METALLOPROTEINASE 3;

AGED; ARTICLE; BEHAVIOR; CASE CONTROL STUDY; DEMOGRAPHY; DISEASE CARRIER; EYE EXAMINATION; FEMALE; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HEREDITY; HOMOZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; MEDICAL PHOTOGRAPHY; OPHTHALMOSCOPY; PRIORITY JOURNAL; RETINA MACULA AGE RELATED DEGENERATION; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 81855198945     PISSN: 00029394     EISSN: 18791891     Source Type: Journal    
DOI: 10.1016/j.ajo.2011.05.016     Document Type: Article

References (45)

1. D.B. Rein, J.S. Wittenborn, X. Zhang, A.A. Honeycutt, S.B. Lesesne, and J. Saaddine Forecasting age-related macular degeneration through the year 2050: the potential impact of new treatments Arch Ophthalmol 127 2009 533 540
2. J.M. Seddon, S. George, and B. Rosner Cigarette smoking, fish consumption, omega-3 fatty acid intake, and associations with age-related macular degeneration: the US Twin Study of Age-Related Macular Degeneration Arch Ophthalmol 124 2006 995 1001 (Pubitemid 44036322)
3. J.M. Seddon, J. Cote, N. Davis, and B. Rosner Progression of age-related macular degeneration: association with body mass index, waist circumference, and waist-hip ratio Arch Ophthalmol 121 2003 785 792 (Pubitemid 36676214)
4. J.M. Seddon, J. Cote, and B. Rosner Progression of age-related macular degeneration: association with dietary fat, transunsaturated fat, nuts, and fish intake Arch Ophthalmol 121 2003 1728 1737 (Pubitemid 37517440)
5. J.M. Seddon, W.C. Willett, F.E. Speizer, and S.E. Hankinson A prospective study of cigarette smoking and age-related macular degeneration in women JAMA 276 1996 1141 1146 (Pubitemid 26329740)
6. J.M. Seddon, U.A. Ajani, and R.D. Sperduto Dietary carotenoids, vitamins A, C, and E, and advanced age-related macular degeneration Eye Disease Case-Control Study Group JAMA 272 1994 1413 1420 (Pubitemid 24328383)
7. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8 Arch Ophthalmol 119 2001 1417 1436
8. S. Haddad, C.A. Chen, S.L. Santangelo, and J.M. Seddon The genetics of age-related macular degeneration: a review of progress to date Surv Ophthalmol 51 2006 316 363 (Pubitemid 43970736)
9. I. Peter, and J.M. Seddon Genetic epidemiology: successes and challenges of genome-wide association studies using the example of age-related macular degeneration Am J Ophthalmol 150 2010 450 452
10. J. Maller, S. George, and S. Purcell Common variation in three genes, including a noncoding variant in CFH, strongly influences risk of age-related macular degeneration Nat Genet 38 2006 1055 1059 (Pubitemid 44325932)
11. A.O. Edwards, R. Ritter 3rd, K.J. Abel, A. Manning, C. Panhuysen, and L.A. Farrer Complement factor H polymorphism and age-related macular degeneration Science 308 2005 421 424 (Pubitemid 40530082)
12. J.L. Haines, M.A. Hauser, and S. Schmidt Complement factor H variant increases the risk of age-related macular degeneration Science 308 2005 419 421 (Pubitemid 40530081)
13. G.S. Hageman, D.H. Anderson, and L.V. Johnson A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration Proc Natl Acad Sci U S A 102 2005 7227 7232 (Pubitemid 40696361)
14. R.J. Klein, C. Zeiss, and E.Y. Chew Complement factor H polymorphism in age-related macular degeneration Science 308 2005 385 389 (Pubitemid 40530070)
15. B. Gold, J.E. Merriam, and J. Zernant Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration Nat Genet 38 2006 458 462
16. J.B. Maller, J.A. Fagerness, R.C. Reynolds, B.M. Neale, M.J. Daly, and J.M. Seddon Variation in complement factor 3 is associated with risk of age-related macular degeneration Nat Genet 39 2007 1200 1201 (Pubitemid 47482689)
17. J.R. Yates, T. Sepp, and B.K. Matharu Complement C3 variant and the risk of age-related macular degeneration N Engl J Med 357 2007 553 561 (Pubitemid 47236280)
18. J.A. Fagerness, J.B. Maller, B.M. Neale, R.C. Reynolds, M.J. Daly, and J.M. Seddon Variation near complement factor I is associated with risk of advanced AMD Eur J Hum Genet 17 2009 100 104
19. Z. Yang, N.J. Camp, and H. Sun A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration Science 314 2006 992 993 (Pubitemid 44749944)
20. J. Jakobsdottir, Y.P. Conley, D.E. Weeks, T.S. Mah, R.E. Ferrell, and M.B. Gorin Susceptibility genes for age-related maculopathy on chromosome 10q26 Am J Hum Genet 77 2005 389 407 (Pubitemid 41192646)
21. A. Dewan, M. Liu, and S. Hartman HTRA1 promoter polymorphism in wet age-related macular degeneration Science 314 2006 989 992 (Pubitemid 44749943)
22. A. Rivera, S.A. Fisher, and L.G. Fritsche Hypothetical LOC387715 is a second major susceptibility gene for age-related macular degeneration, contributing independently of complement factor H to disease risk Hum Mol Genet 14 2005 3227 3236 (Pubitemid 41631297)
23. J.M. Seddon, R. Reynolds, J. Maller, J.A. Fagerness, M.J. Daly, and B. Rosner Prediction model for prevalence and incidence of advanced age-related macular degeneration based on genetic, demographic, and environmental variables Invest Ophthalmol Vis Sci 50 2009 2044 2053
24. B.M. Neale, J. Fagerness, and R. Reynolds Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC) Proc Natl Acad Sci U S A 107 2010 7395 7400
25. W. Chen, D. Stambolian, and A.O. Edwards Genetic variants near TIMP3 and high-density lipoprotein associated loci influence susceptibility to age-related macular degeneration Proc Natl Acad Sci U S A 107 2010 7401 7406
26. F. Panza, A. D'Introno, and C. Capurso Lipoproteins, vascular-related genetic factors, and human longevity Rejuvenation Res 107 2007 441 458
27. G.L. Anderson, J. Manson, and R. Wallace Implementation of the Women's Health Initiative study design Ann Epidemiol 13 2003 S5 S17
28. M.N. Haan, R. Klein, and B.E. Klein Hormone therapy and age-related macular degeneration: the Women's Health Initiative Sight Exam Study Arch Ophthalmol 124 2006 988 992 (Pubitemid 44036321)
29. J. Seddon, and L. Sobrin Epidemiology of age-related macular degeneration D.M. Albert, J. Miller, The Principles and Practice of Ophthalmology 3rd ed. 2007 W.B. Saunders Philadelphia 413 422
30. R. Klein, B.E. Klein, S.C. Tomany, S.M. Meuer, and G.H. Huang Ten-year incidence and progression of age-related maculopathy: The Beaver Dam eye study Ophthalmology 109 2002 1767 1779
31. R. Klein, M.D. Davis, Y.L. Magli, P. Segal, B.E. Klein, and L. Hubbard The Wisconsin age-related maculopathy grading system Ophthalmology 98 1991 1128 1134
32. Y.S. Aulchenko, S. Ripatti, and I. Lindqvist Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts Nat Genet 41 2009 47 55
33. J.S. Kooner, J.C. Chambers, and C.A. Aguilar-Salinas Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides Nat Genet 40 2008 149 151 (Pubitemid 351171393)
34. S. Kathiresan, C.J. Willer, and G.M. Peloso Common variants at 30 loci contribute to polygenic dyslipidemia Nat Genet 41 2009 56 65
35. C.J. Willer, S. Sanna, and A.U. Jackson Newly identified loci that influence lipid concentrations and risk of coronary artery disease Nat Genet 40 2008 161 169 (Pubitemid 351171403)
36. R. Saxena, B.F. Voight, and V. Lyssenko Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels Science 316 2007 1331 1336 (Pubitemid 46871653)
37. R. Reynolds, B. Rosner, and J. Seddon Serum lipid biomarkers and hepatic lipase gene associations with age-related macular degeneration Ophthalmology 117 2010 1989 1995
38. C.A. Curcio, M. Johnson, J.D. Huang, and M. Rudolf Aging, age-related macular degeneration, and the response-to-retention of apolipoprotein B-containing lipoproteins Prog Retin Eye Res 28 2009 393 422
39. R.W. Mahley, T.L. Innerarity, S.C. Rall Jr, and K.H. Weisgraber Plasma lipoproteins: apolipoprotein structure and function J Lipid Res 25 1984 1277 1294 (Pubitemid 15150638)
40. S.J. Lee, J.H. Kim, and M.J. Chung Human apolipoprotein E2 transgenic mice show lipid accumulation in retinal pigment epithelium and altered expression of VEGF and bFGF in the eyes J Microbiol Biotechnol 17 2007 1024 1030 (Pubitemid 47162068)
41. T. Ishida, S.Y. Choi, and R.K. Kundu Endothelial lipase modulates susceptibility to atherosclerosis in apolipoprotein-E-deficient mice J Biol Chem 279 2004 45085 45092 (Pubitemid 39430923)
42. S.J. Lewis, and E.J. Brunner Methodological problems in genetic association studies of longevitythe apolipoprotein E gene as an example Int J Epidemiol 33 2004 962 970 (Pubitemid 39429988)
43. D.S. Friedman, B.J. O'Colmain, and B. Munoz Prevalence of age-related macular degeneration in the United States Arch Ophthalmol 122 2004 564 572 (Pubitemid 38456293)
44. Y. Li, L. Xu, J.B. Jonas, H. Yang, Y. Ma, and J. Li Prevalence of age-related maculopathy in the adult population in China: the Beijing eye study Am J Ophthalmol 142 2006 788 793
45. Y. Oshima, T. Ishibashi, T. Murata, Y. Tahara, Y. Kiyohara, and T. Kubota Prevalence of age related maculopathy in a representative Japanese population: the Hisayama study Br J Ophthalmol 85 2001 1153 1157 (Pubitemid 32929535)