Synergistic effects of glutamine and ciprofloxacin in reduction of Pseudomonas aeruginosa-induced septic shock severity

International Immunopharmacology

Volumn 11, Issue 12, 2011, Pages 2214-2219

  Mazloomi, Ebrahim ^a   Jazani, Nima Hosseini ^b   Sohrabpour, Mohammad ^a   Ilkhanizadeh, Behrouz ^c   Shahabi, Shahram ^b  

^a ISLAMIC AZAD UNIVERSITY   (Iran)

^b URMIA UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c URMIA UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Glutamine; HSP 70; IL 10; Pseudomonas aeruginosa; Septic shock; TNF

Indexed keywords

ALANINE; BUFFER; CIPROFLOXACIN; GLUTAMINE; HEAT SHOCK PROTEIN 70; INTERLEUKIN 10; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BAGG ALBINO MOUSE; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EFFECT; DRUG POTENTIATION; LETHAL DOSE; LIVER NECROSIS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; RISK REDUCTION; SEPTIC SHOCK; SURVIVAL RATE;

ANIMALS; CIPROFLOXACIN; DRUG SYNERGISM; DRUG THERAPY, COMBINATION; GLUTAMINE; HSP70 HEAT-SHOCK PROTEINS; INTERLEUKIN-10; LIVER CIRRHOSIS, EXPERIMENTAL; MALE; MICE; MICE, INBRED BALB C; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; SEVERITY OF ILLNESS INDEX; SHOCK, SEPTIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 81855197062     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2011.10.003     Document Type: Article

References (30)

1. M.R. Morrell, S.T. Micek, and M.H. Kollef The management of severe sepsis and septic shock Infect Dis Clin North Am 23 2009 485 501
2. X.L. Wang, Y. Li, J.S. Kuang, Y. Zhao, and P. Liu Increased heat shock protein 70 expression in the pancreas of rats with endotoxic shock World J Gastroenterol 12 2006 780 783 (Pubitemid 43380764)
3. U.H. Ha, Y. Wang, and S. Jin DsbA of Pseudomonas aeruginosa is essential for multiple virulence factors Infect Immun 71 2003 1590 1595 (Pubitemid 36254353)
4. T. Matsumoto, K. Tateda, S. Miyazaki, N. Furuya, A. Ohno, and Y. Ishii Immunomodulating effect of fosfomycin on gut-derived sepsis caused by Pseudomonas aeruginosa in mice Antimicrob Agents Chemother 41 1997 308 313 (Pubitemid 27111023)
5. D. Ang, K. Liberek, D. Skowyra, M. Zylicz, and C. Georgopoulos Biological role and regulation of the universally conserved heat shock proteins J Biol Chem 266 1991 24233 24236 (Pubitemid 21908929)
6. I.J. Benjamin, and D.R. McMillan Stress (heat shock) proteins: molecular chaperones in cardiovascular biology and disease Circ Res 83 1998 117 132 (Pubitemid 28354456)
7. R.J. Ellis, and S.M. Hemmingsen Molecular chaperones: proteins essential for the biogenesis of some macromolecular structures Trends Biochem Sci 14 1989 339 342 (Pubitemid 19191344)
8. P.M. Anderson, G. Schroeder, and K.M. Skubitz Oral glutamine reduces the duration and severity of stomatitis after cytotoxic cancer chemotherapy Cancer 83 1998 1433 1439
9. A. Hubert-Buron, J. Leblond, A. Jacquot, P. Ducrotte, P. Dechelotte, and M. Coeffier Glutamine pretreatment reduces IL-8 production in human intestinal epithelial cells by limiting IkappaBalpha ubiquitination J Nutr 136 2006 1461 1465 (Pubitemid 43765345)
10. S.L. Yeh, Y.N. Lai, H.F. Shang, M.T. Lin, and W.J. Chen Effects of glutamine supplementation on innate immune response in rats with gut-derived sepsis Br J Nutr 91 2004 423 429
11. M. Moon, T. Pritts, A. Salzman, J. Fischer, and P. Hasselgren Glutamine prevents LPS-induced NF-kB activation in human intestinal epithelial cells Gastroenterology 114 1998 1410 1411
12. Y.S. Kim, G.Y. Kim, J.H. Kim, H.J. You, Y.M. Park, and H.K. Lee Glutamine inhibits lipopolysaccharide-induced cytoplasmic phospholipase A2 activation and protects against endotoxin shock in mouse Shock 25 2006 290 294
13. C.K. Ameho, A.A. Adjei, E.K. Harrison, K. Takeshita, T. Morioka, and Y. Arakaki Prophylactic effect of dietary glutamine supplementation on interleukin 8 and tumour necrosis factor alpha production in trinitrobenzene sulphonic acid induced colitis Gut 41 1997 487 493 (Pubitemid 27448780)
14. M. Coeffier, O. Miralles-Barrachina, F. Le Pessot, O. Lalaude, M. Daveau, and A. Lavoinne Influence of glutamine on cytokine production by human gut in vitro Cytokine 13 2001 148 154 (Pubitemid 32579303)
15. K.D. Singleton, and P.E. Wischmeyer Oral glutamine enhances heat shock protein expression and improves survival following hyperthermia Shock 25 2006 295 299
16. P.E. Wischmeyer Glutamine and heat shock protein expression Nutrition 18 2002 225 228 (Pubitemid 34204132)
17. P.E. Wischmeyer, M. Kahana, R. Wolfson, H. Ren, M.M. Musch, and E.B. Chang Glutamine induces heat shock protein and protects against endotoxin shock in the rat J Appl Physiol 90 2001 2403 2410 (Pubitemid 32467436)
18. A. Arguedas, H. Sierra, and C. Soley Fluoroquinolones in Pediatrics Curr Drug Ther 1 2006 117 125
19. M.A. Wikler Performance standards for antimicrobial disk susceptibility tests; approved standard ninth edition C L S I 21 2006 10 49
20. L. Jing, Q. Wu, and F. Wang Glutamine induces heat-shock protein and protects against Escherichia coli lipopolysaccharide-induced vascular hyporeactivity in rats Crit Care 11 2007 R34
21. R. Raina, S. Prawez, D.J. Dimitrova, N.K. Pankaj, and P.K. Verma Disposition kinetics and urinary excretion of ciprofloxacin in goats following single intravenous administration J Vet Sci 9 2008 241 245
22. G.L. Su, K.Q. Gong, M.H. Fan, W.M. Kelley, J. Hsieh, and J.M. Sun Lipopolysaccharide-binding protein modulates acetaminophen-induced liver injury in mice Hepatology 41 2005 187 195 (Pubitemid 40066397)
23. K.D. Kaita, N. Assy, T. Gauthier, M. Zhang, A.F. Meyers, and G.Y. Minuk The beneficial effects of ciprofloxacin on survival and hepatic regenerative activity in a rat model of fulminant hepatic failure Hepatology 27 1998 533 536 (Pubitemid 28081070)
24. K.D. Singleton, N. Serkova, V.E. Beckey, and P.E. Wischmeyer Glutamine attenuates lung injury and improves survival after sepsis: role of enhanced heat shock protein expression Crit Care Med 33 2005 1206 1213 (Pubitemid 40827366)
25. P.E. Wischmeyer, M. Kahana, R. Wolfson, H. Ren, M.M. Musch, and E.B. Chang Glutamine reduces cytokine release, organ damage, and mortality in a rat model of endotoxemia Shock 16 2001 398 402 (Pubitemid 33598218)
26. R.G. Garrett-Cox, G. Stefanutti, C. Booth, N.J. Klein, A. Pierro, and S. Eaton Glutamine decreases inflammation in infant rat endotoxemia J Pediatr Surg 44 2009 523 529
27. A. Szijarto, O. Hahn, E. Batmunkh, R. Stangl, A. Kiss, and G. Lotz Short-term alanyl-glutamine dipeptide pretreatment in liver ischemia-reperfusion model: effects on microcirculation and antioxidant status in rats Clin Nutr 26 2007 640 648 (Pubitemid 47618325)
28. A.G. Pockley, and G. Multhoff Circulating HSP70 as an endogenous cytoprotector? A.A.A. Asea, B.K. Pedersen, Heat shock proteins and whole body physiology 2010 Springer Dorrecht 317 326
29. A.G. Pockley, A. Georgiades, T. Thulin, U. de Faire, and J. Frostegard Serum heat shock protein 70 levels predict the development of atherosclerosis in subjects with established hypertension Hypertension 42 2003 235 238 (Pubitemid 37093466)
30. T.R. Ziegler, L.G. Ogden, K.D. Singleton, M. Luo, C. Fernandez-Estivariz, and D.P. Griffith Parenteral glutamine increases serum heat shock protein 70 in critically ill patients Intensive Care Med 31 2005 1079 1086 (Pubitemid 41125339)