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Volumn 155, Issue 1, 2012, Pages 71-80

Expression regulation triggers oncogenicity of xmrk alleles in the Xiphophorus melanoma system

Author keywords

EGF receptor; Hybrid; Melanoma; Pigment cell; Transcriptional control; Tumor suppressor; Xiphophorus; xmrk

Indexed keywords

BETA ACTIN; EPIDERMAL GROWTH FACTOR RECEPTOR; PROTEIN TYROSINE KINASE; PROTEIN XMRK; UNCLASSIFIED DRUG;

EID: 81855182126     PISSN: 15320456     EISSN: 18781659     Source Type: Journal    
DOI: 10.1016/j.cbpc.2011.04.003     Document Type: Conference Paper
Times cited : (12)

References (48)
  • 1
    • 0027464696 scopus 로고
    • Tumor suppression in Xiphophorus by an accidentally acquired promoter
    • D. Adam, N. Dimitrijevic, and M. Schartl Tumor suppression in Xiphophorus by an accidentally acquired promoter Science 259 1993 816 819 (Pubitemid 23066311)
    • (1993) Science , vol.259 , Issue.5096 , pp. 816-819
    • Adam, D.1    Dimitrijevic, N.2    Schartl, M.3
  • 2
    • 0026083794 scopus 로고
    • Transcriptional activation of the melanoma inducing Xmrk oncogene in Xiphophorus
    • D. Adam, W. Maueler, and M. Schartl Transcriptional activation of the melanoma inducing Xmrk oncogene in Xiphophorus Oncogene 6 1991 73 80 (Pubitemid 21923984)
    • (1991) Oncogene , vol.6 , Issue.1 , pp. 73-80
    • Adam, D.1    Maueler, W.2    Schartl, M.3
  • 3
    • 0019084803 scopus 로고
    • Linkage between a regulatory locus for melanoma cell differentiation and an esterase locus in Xiphophorus
    • M.R. Ahuja, M. Schwab, and F. Anders Linkage between a regulatory locus for melanoma cell differentiation and an esterase locus in Xiphophorus J Hered 71 1980 403 407
    • (1980) J Hered , vol.71 , pp. 403-407
    • Ahuja, M.R.1    Schwab, M.2    Anders, F.3
  • 4
    • 0031453977 scopus 로고    scopus 로고
    • Hypomethylation of the Xmrk oncogene promoter in melanoma cells of Xiphophorus
    • J. Altschmied, L. Ditzel, and M. Schartl Hypomethylation of the Xmrk oncogene promoter in melanoma cells of Xiphophorus Biol Chem 378 1997 1457 1466 (Pubitemid 28014879)
    • (1997) Biological Chemistry , vol.378 , Issue.12 , pp. 1457-1466
    • Altschmied, J.1    Ditzel, L.2    Schartl, M.3
  • 5
    • 74049135297 scopus 로고    scopus 로고
    • Global repression of cancer gene expression in a zebrafish model of melanoma is linked to epigenetic regulation
    • V. Anelli, C. Santoriello, M. Distel, R.W. Koster, F.D. Ciccarelli, and M. Mione Global repression of cancer gene expression in a zebrafish model of melanoma is linked to epigenetic regulation Zebrafish 6 2009 417 424
    • (2009) Zebrafish , vol.6 , pp. 417-424
    • Anelli, V.1    Santoriello, C.2    Distel, M.3    Koster, R.W.4    Ciccarelli, F.D.5    Mione, M.6
  • 6
    • 41049114747 scopus 로고    scopus 로고
    • How to make a melanoma: What do we know of the primary clonal events?
    • DOI 10.1111/j.1755-148X.2007.00433.x
    • D.C. Bennett How to make a melanoma: what do we know of the primary clonal events? Pigment Cell Melanoma Res 21 2008 27 38 (Pubitemid 351421467)
    • (2008) Pigment Cell and Melanoma Research , vol.21 , Issue.1 , pp. 27-38
    • Bennett, D.C.1
  • 9
    • 0032473868 scopus 로고    scopus 로고
    • Activation of the Xmrk proto-oncogene of Xiphophorus by overexpression and mutational alterations
    • N. Dimitrijevic, C. Winkler, C. Wellbrock, A. Gomez, J. Duschl, J. Altschmied, and M. Schartl Activation of the Xmrk proto-oncogene of Xiphophorus by overexpression and mutational alterations Oncogene 16 1998 1681 1690 (Pubitemid 28175049)
    • (1998) Oncogene , vol.16 , Issue.13 , pp. 1681-1690
    • Dimitrijevic, N.1    Winkler, C.2    Wellbrock, C.3    Gomez, A.4    Duschl, J.5    Altschmied, J.6    Schartl, M.7
  • 10
    • 74049101047 scopus 로고    scopus 로고
    • Oncogenic NRAS cooperates with p53 loss to generate melanoma in zebrafish
    • M. Dovey, R.M. White, and L.I. Zon Oncogenic NRAS cooperates with p53 loss to generate melanoma in zebrafish Zebrafish 6 2009 397 404
    • (2009) Zebrafish , vol.6 , pp. 397-404
    • Dovey, M.1    White, R.M.2    Zon, L.I.3
  • 11
    • 77954854885 scopus 로고    scopus 로고
    • Selection for a dominant oncogene and large male size as a risk factor for melanoma in the Xiphophorus animal model
    • A.A. Fernandez, and P.R. Bowser Selection for a dominant oncogene and large male size as a risk factor for melanoma in the Xiphophorus animal model Mol Ecol 19 2010 3114 3123
    • (2010) Mol Ecol , vol.19 , pp. 3114-3123
    • Fernandez, A.A.1    Bowser, P.R.2
  • 12
    • 0026332165 scopus 로고
    • Analysis of an esterase linked to a locus involved in the regulation of the melanoma oncogene and isolation of polymorphic marker sequences in Xiphophorus
    • D. Förnzler, J. Wittbrodt, and M. Schartl Analysis of an esterase linked to a locus involved in the regulation of the melanoma oncogene and isolation of polymorphic marker sequences in Xiphophorus Biochem Genet 29 1991 509 524
    • (1991) Biochem Genet , vol.29 , pp. 509-524
    • Förnzler, D.1    Wittbrodt, J.2    Schartl, M.3
  • 14
    • 0035793558 scopus 로고    scopus 로고
    • Ligand-independent dimerization and activation of the oncogenic Xmrk receptor by two mutations in the extracellular domain
    • A. Gomez, C. Wellbrock, H. Gutbrod, N. Dimitrijevic, and M. Schartl Ligand-independent dimerization and activation of the oncogenic Xmrk receptor by two mutations in the extracellular domain J Biol Chem 276 2001 3333 3340
    • (2001) J Biol Chem , vol.276 , pp. 3333-3340
    • Gomez, A.1    Wellbrock, C.2    Gutbrod, H.3    Dimitrijevic, N.4    Schartl, M.5
  • 15
    • 0000035303 scopus 로고
    • The genetics of viviparous top-minnow Platypoecilus: The inheritance of two kinds of melanophores
    • M. Gordon The genetics of viviparous top-minnow Platypoecilus: the inheritance of two kinds of melanophores Genetics 12 1927 253 283
    • (1927) Genetics , vol.12 , pp. 253-283
    • Gordon, M.1
  • 16
    • 0032955006 scopus 로고    scopus 로고
    • Intragenic sex-chromosomal crossover of Xmrk oncogene alleles affect pigment pattern formation and the severity of melanoma in Xiphophorus
    • H. Gutbrod, and M. Schartl Intragenic sex-chromosomal crossovers of Xmrk oncogene alleles affect pigment pattern formation and the severity of melanoma in Xiphophorus Genetics 151 1999 773 783 (Pubitemid 29082943)
    • (1999) Genetics , vol.151 , Issue.2 , pp. 773-783
    • Gutbrod, H.1    Schartl, M.2
  • 17
    • 0001296157 scopus 로고
    • Über Melanombildungen bei Bastarden von Xiphophorus maculatus var. rubra
    • G. Häussler Über Melanombildungen bei Bastarden von Xiphophorus maculatus var. rubra Klin Wochenschr 7 1928 1561 1562
    • (1928) Klin Wochenschr , vol.7 , pp. 1561-1562
    • Häussler, G.1
  • 18
    • 0002479158 scopus 로고
    • The platyfish, Xiphophorus maculatus
    • K. RC, Plenum Press New York, N.Y
    • K. Kallman The platyfish, Xiphophorus maculatus K. RC, Handbook of Genetics 1975 Plenum Press New York, N.Y 81 132
    • (1975) Handbook of Genetics , pp. 81-132
    • Kallman, K.1
  • 21
    • 0033539080 scopus 로고    scopus 로고
    • Comparative structure and characterization of a CDKN2 gene in a Xiphophorus fish melanoma model
    • DOI 10.1038/sj.onc.1202884
    • S. Kazianis, D.C. Morizot, L.D. Coletta, D.A. Johnston, B. Woolcock, J.R. Vielkind, and R.S. Nairn Comparative structure and characterization of a CDKN2 gene in a Xiphophorus fish melanoma model Oncogene 18 1999 5088 5099 (Pubitemid 29443754)
    • (1999) Oncogene , vol.18 , Issue.36 , pp. 5088-5099
    • Kazianis, S.1    Morizot, D.C.2    Della Coletta, L.3    Johnston, D.A.4    Woolcock, B.5    Vielkind, J.R.6    Nairn, R.S.7
  • 22
    • 0034665737 scopus 로고    scopus 로고
    • Genetic analysis of melanophore development in zebrafish embryos
    • R. Kelsh Genetic analysis of melanophore development in zebrafish embryos Dev Biol 225 2000 277 293
    • (2000) Dev Biol , vol.225 , pp. 277-293
    • Kelsh, R.1
  • 23
    • 34347193937 scopus 로고
    • Über Kreuzungen zwischen den Teleostiern Xiphophorus helleri und Platypoecilus maculatus
    • C. Kosswig Über Kreuzungen zwischen den Teleostiern Xiphophorus helleri und Platypoecilus maculatus Z Indukt Abstammungs Vererbungsl 47 1928 150 158
    • (1928) Z Indukt Abstammungs Vererbungsl , vol.47 , pp. 150-158
    • Kosswig, C.1
  • 25
    • 0035710746 scopus 로고    scopus 로고
    • -ΔΔCT method
    • DOI 10.1006/meth.2001.1262
    • K.J. Livak, and T.D. Schmittgen Analysis of relative gene expression data using real-time quantitative PCR and the 2(- Delta Delta C(T)) method Methods 25 2001 402 408 (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 26
    • 0028276959 scopus 로고
    • Autocrine stimulation of the Xmrk receptor tyrosine kinase in Xiphophorus melanoma cells and identification of a source for the physiological ligand
    • B. Malitschek, J. Wittbrodt, P. Fischer, R. Lammers, A. Ullrich, and M. Schartl Autocrine stimulation of the Xmrk receptor tyrosine kinase in Xiphophorus melanoma cells and identification of a source for the physiological ligand J Biol Chem 269 1994 10423 10430 (Pubitemid 24198238)
    • (1994) Journal of Biological Chemistry , vol.269 , Issue.14 , pp. 10423-10430
    • Malitschek, B.1    Wittbrodt, J.2    Fischer, P.3    Lammers, R.4    Ullrich, A.5    Schartl, M.6
  • 27
    • 0027361489 scopus 로고
    • Different expression patterns of oncogenes and proto-oncogenes in hereditary and carcinogen-induced tumors of xiphophorus
    • W. Mäueler, A. Schartl, and M. Schartl Different expression patterns of oncogenes and proto-oncogenes in hereditary and carcinogen-induced tumors of Xiphophorus Int J Cancer 55 1993 288 296 (Pubitemid 23296030)
    • (1993) International Journal of Cancer , vol.55 , Issue.2 , pp. 288-296
    • Maueler, W.1    Schartl, A.2    Schartl, M.3
  • 28
    • 33750028210 scopus 로고    scopus 로고
    • A structural model of the extracellular domain of the oncogenic EGFR variant Xmrk
    • DOI 10.1089/zeb.2006.3.359
    • S. Meierjohann, T. Müller, M. Schartl, and M. Bühner A structural model of the extracellular domain of the oncogenic EGFR variant Xmrk Zebrafish 3 2006 359 369 (Pubitemid 44569745)
    • (2006) Zebrafish , vol.3 , Issue.3 , pp. 359-369
    • Meierjohann, S.1    Mueller, T.2    Schartl, M.3    Buehner, M.4
  • 29
    • 33750942658 scopus 로고    scopus 로고
    • From Mendelian to molecular genetics: The Xiphophorus melanoma model
    • DOI 10.1016/j.tig.2006.09.013, PII S0168952506003362
    • S. Meierjohann, and M. Schartl From Mendelian to molecular genetics: the Xiphophorus melanoma model Trends Genet 22 2006 654 661 (Pubitemid 44738129)
    • (2006) Trends in Genetics , vol.22 , Issue.12 , pp. 654-661
    • Meierjohann, S.1    Schartl, M.2
  • 30
    • 7944235803 scopus 로고    scopus 로고
    • Genetic, biochemical and evolutionary facets of Xmrk-induced melanoma formation in the fish Xiphophorus
    • DOI 10.1016/j.cca.2004.06.002, PII S1532045604001024, Aquatic Animal Models of Human Disease
    • S. Meierjohann, M. Schartl, and J.N. Volff Genetic, biochemical and evolutionary facets of Xmrk-induced melanoma formation in the fish Xiphophorus Comp Biochem Physiol C Toxicol Pharmacol 138 2004 281 289 (Pubitemid 39469063)
    • (2004) Comparative Biochemistry and Physiology - C Toxicology and Pharmacology , vol.138 , Issue.3 , pp. 281-289
    • Meierjohann, S.1    Schartl, M.2    Volff, J.-N.3
  • 31
    • 0021062579 scopus 로고
    • Linkage group V of platyfishes and swordtails of the genus Xiphophorus (Peociliidae): Linkage of loci for malate dehydrogenase-2 and esterase-1 and esterase-4 with a gene controlling the severity of hybrid melanomas
    • D.C. Morizot, and M.J. Siciliano Linkage group V of platyfishes and swordtails of the genus Xiphophorus (Poeciliidae): linkage of loci for malate dehydrogenase-2 and esterase-1 and esterase-4 with a gene controlling the severity of hybrid melanomas J Natl Cancer Inst 71 1983 809 813 (Pubitemid 14232397)
    • (1983) Journal of the National Cancer Institute , vol.71 , Issue.4 , pp. 809-813
    • Morizot, D.C.1    Siciliano, M.J.2
  • 36
    • 0028926540 scopus 로고
    • Platyfish and swordtails: A genetic system for the analysis of molecular mechanisms in tumor formation
    • M. Schartl Platyfish and swordtails: a genetic system for the analysis of molecular mechanisms in tumor formation Trends Genet 11 1995 185 189
    • (1995) Trends Genet , vol.11 , pp. 185-189
    • Schartl, M.1
  • 37
    • 0032710999 scopus 로고    scopus 로고
    • Melanoma loss-of-function mutants in Xiphophorus caused by Xmrk-oncogene deletion and gene disruption by a transposable element
    • M. Schartl, U. Hornung, H. Gutbrod, J.N. Volff, and J. Wittbrodt Melanoma loss-of-function mutants in Xiphophorus caused by Xmrk- oncogene deletion and gene disruption by a transposable element Genetics 153 1999 1385 1394 (Pubitemid 29522149)
    • (1999) Genetics , vol.153 , Issue.3 , pp. 1385-1394
    • Schartl, M.1    Hornung, U.2    Gutbrod, H.3    Volff, J.-N.4    Wittbrodt, J.5
  • 39
    • 72049113079 scopus 로고    scopus 로고
    • A mutated EGFR is sufficient to induce malignant melanoma with genetic background-dependent histopathologies
    • M. Schartl, B. Wilde, J.A. Laisney, Y. Taniguchi, S. Takeda, and S. Meierjohann A mutated EGFR is sufficient to induce malignant melanoma with genetic background-dependent histopathologies J Invest Dermatol 130 2009 249 258
    • (2009) J Invest Dermatol , vol.130 , pp. 249-258
    • Schartl, M.1    Wilde, B.2    Laisney, J.A.3    Taniguchi, Y.4    Takeda, S.5    Meierjohann, S.6
  • 42
    • 0019382251 scopus 로고
    • Establishment of a cell line from the platyfish-swordtail hybrid melanoma
    • Y. Wakamatsu Establishment of a cell line from the platyfish-swordtail hybrid melanoma Cancer Res 41 1981 679 680 (Pubitemid 11179415)
    • (1981) Cancer Research , vol.41 , Issue.2 , pp. 679-680
    • Wakamatsu, Y.1
  • 43
    • 0031927348 scopus 로고    scopus 로고
    • The macromelanophore locus and the melanoma oncogene Xmrk are separate genetic entities in the genome of Xiphophorus
    • S. Weis, and M. Schartl The macromelanophore locus and the melanoma oncogene Xmrk are separate genetic entities in the genome of Xiphophorus Genetics 149 1998 1909 1920 (Pubitemid 28375960)
    • (1998) Genetics , vol.149 , Issue.4 , pp. 1909-1920
    • Weis, S.1    Schartl, M.2
  • 44
    • 0028272397 scopus 로고
    • Ligand-dependent tumor induction in medakafish embryos by a Xmrk receptor tyrosine kinase transgene
    • C. Winkler, J. Wittbrodt, R. Lammers, A. Ullrich, and M. Schartl Ligand-dependent tumor induction in medakafish embryos by a Xmrk receptor tyrosine kinase transgene Oncogene 9 1994 1517 1525 (Pubitemid 24163376)
    • (1994) Oncogene , vol.9 , Issue.6 , pp. 1517-1525
    • Winkler, C.1    Wittbrodt, J.2    Lammers, R.3    Ullrich, A.4    Schartl, M.5
  • 45
    • 27744551090 scopus 로고    scopus 로고
    • Activating mutations in the extracellular domain of the melanoma inducing receptor Xmrk are tumorigenic in vivo
    • DOI 10.1002/ijc.21232
    • D. Winnemoeller, C. Wellbrock, and M. Schartl Activating mutations in the extracellular domain of the melanoma inducing receptor Xmrk are tumorigenic in vivo Int J Cancer 117 2005 723 729 (Pubitemid 41598822)
    • (2005) International Journal of Cancer , vol.117 , Issue.5 , pp. 723-729
    • Winnemoeller, D.1    Wellbrock, C.2    Schartl, M.3
  • 46
    • 0024449217 scopus 로고
    • Novel putative receptor tyrosine kinase encoded by the melanoma-inducing Tu locus in Xiphophorus
    • DOI 10.1038/341415a0
    • J. Wittbrodt, D. Adam, B. Malitschek, W. Maueler, F. Raulf, A. Telling, S.M. Robertson, and M. Schartl Novel putative receptor tyrosine kinase encoded by the melanoma-inducing Tu locus in Xiphophorus Nature 341 1989 415 421 (Pubitemid 19241907)
    • (1989) Nature , vol.341 , Issue.6241 , pp. 415-421
    • Wittbrodt, J.1    Adam, D.2    Malitschek, B.3    Maueler, W.4    Raulf, F.5    Telling, A.6    Robertson, S.M.7    Schartl, M.8
  • 47
    • 0026657858 scopus 로고
    • The Xmrk receptor tyrosine kinase is activated in Xiphophorus malignant melanoma
    • J. Wittbrodt, R. Lammers, B. Malitschek, A. Ullrich, and M. Schartl The Xmrk receptor tyrosine kinase is activated in Xiphophorus malignant melanoma EMBO J 11 1992 4239 4246
    • (1992) EMBO J , vol.11 , pp. 4239-4246
    • Wittbrodt, J.1    Lammers, R.2    Malitschek, B.3    Ullrich, A.4    Schartl, M.5
  • 48
    • 0028058884 scopus 로고
    • Differences in transcription and promoters of Xmrk-1 and Xmrk-2 genes suggest a role for Xmrk-2 in pigment pattern development in the platyfish, Xiphophorus maculatus
    • B.W. Woolcock, B.M. Schmidt, K.D. Kallman, and J.R. Vielkind Differences in transcription and promoters of Xmrk-1 and Xmrk-2 genes suggest a role for Xmrk-2 in pigment pattern development in the platyfish, Xiphophorus maculatus Cell Growth Differ 5 1994 575 583 (Pubitemid 24252322)
    • (1994) Cell Growth and Differentiation , vol.5 , Issue.6 , pp. 575-583
    • Woolcock, B.W.1    Schmidt, B.M.2    Kallman, K.D.3    Vielkind, J.R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.