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Volumn 4, Issue 3, 2011, Pages 442-456

Frequency-dependent focal adhesion instability and cell reorientation under cyclic substrate stretching

Author keywords

Cell adhesion; Loading frequency; Mechano chemical coupling; Mechanosensitivity; Multiscale modeling; Stress fiber

Indexed keywords

ARTICLE; CELL ADHESION; CELL FUNCTION; CELL REORIENTATION; CHEMOSENSITIVITY; CONCEPTUAL FRAMEWORK; CONTROLLED STUDY; DEPOLYMERIZATION; EXTRACELLULAR MATRIX; FOCAL ADHESION; FOCAL ADHESION INSTABILITY; FREQUENCY DEPENDENT SELECTION; LIGAND BINDING; MATHEMATICAL MODEL; MECHANICAL STRESS; MECHANOCHEMICAL COUPLING; MOLECULAR DYNAMICS; POLYMERIZATION; PRIORITY JOURNAL; RIGIDITY; SIMULATION; STRESS FIBER; SUBSTRATE STRETCHING; TIME; VISCOELASTICITY;

EID: 81855176061     PISSN: 18655025     EISSN: 18655033     Source Type: Journal    
DOI: 10.1007/s12195-011-0187-6     Document Type: Article
Times cited : (32)

References (57)
  • 2
    • 56049124109 scopus 로고    scopus 로고
    • Temporal evolution of cell focal adhesions: Experimental observations and shear stress profiles
    • Aroush, D. R. B., R. Zaidel-Bar, A. D. Bershadsky, and H. D. Wagner. Temporal evolution of cell focal adhesions: Experimental observations and shear stress profiles. Soft Matter 4:2410-2417, 2008.
    • (2008) Soft Matter , vol.4 , pp. 2410-2417
    • Aroush, D.R.B.1    Zaidel-Bar, R.2    Bershadsky, A.D.3    Wagner, H.D.4
  • 4
    • 0018101150 scopus 로고
    • Models for the specific adhesion of cells to cells
    • Bell, G. I. Models for the specific adhesion of cells to cells. Science 200:618-627, 1978.
    • (1978) Science , vol.200 , pp. 618-627
    • Bell, G.I.1
  • 5
    • 0021250906 scopus 로고
    • Cell adhesion. Competition between nonspecific repulsion and specific bonding
    • Bell, G. I., M. Dembo, and P. Bongrand. Cell adhesion. Competition between nonspecific repulsion and specific bonding. Biophys. J. 45:1051-1064, 1984. (Pubitemid 14099481)
    • (1984) Biophysical Journal , vol.45 , Issue.6 , pp. 1051-1064
    • Bell, G.I.1    Dembo, M.2    Bongrand, P.3
  • 6
    • 0035858878 scopus 로고    scopus 로고
    • Nascent focal adhesions are responsible for the generation of strong propulsive forces in migrating fibroblasts
    • Beningo, K. A., M. Dembo, I. Kaverina, J. V. Small, and Y.-L. Wang. Nascent focal adhesions are responsible for the generation of strong propulsive forces in migrating fibroblasts. J. Cell Biol. 153:881-888, 2001.
    • (2001) J. Cell Biol. , vol.153 , pp. 881-888
    • Beningo, K.A.1    Dembo, M.2    Kaverina, I.3    Small, J.V.4    Wang, Y.-L.5
  • 8
    • 33748309166 scopus 로고    scopus 로고
    • Adhesion-mediated mechanosensitivity: A time to experiment, and a time to theorize
    • DOI 10.1016/j.ceb.2006.08.012, PII S0955067406001232
    • Bershadsky, A., M. Kozlov, and B. Geiger. Adhesionmediated mechanosensitivity: A time to experiment, and a time to theorize. Curr. Opin. Cell Biol. 18:472-481, 2006. (Pubitemid 44332917)
    • (2006) Current Opinion in Cell Biology , vol.18 , Issue.5 , pp. 472-481
    • Bershadsky, A.1    Kozlov, M.2    Geiger, B.3
  • 9
    • 0004150063 scopus 로고    scopus 로고
    • Cambridge UK: Cambridge University Press
    • Boal, D. Mechanics of the Cell. Cambridge, UK: Cambridge University Press, 2002.
    • (2002) Mechanics of the Cell
    • Boal, D.1
  • 10
    • 0030872850 scopus 로고    scopus 로고
    • Adhesive interactions in the immune system
    • DOI 10.1016/S0962-8924(97)01076-3, PII S0962892497010763
    • Brown, E. J. Adhesive interactions in the immune system. Trends Cell Biol. 7:289-295, 1997. (Pubitemid 27352944)
    • (1997) Trends in Cell Biology , vol.7 , Issue.7 , pp. 289-295
    • Brown, E.J.1
  • 11
    • 34147098381 scopus 로고    scopus 로고
    • Cell spreading and focal adhesion dynamics are regulated by spacing of integrin ligands
    • DOI 10.1529/biophysj.106.089730
    • Cavalcanti-Adam, E. A., T. Volberg, A. Micoulet, H. Kessler, B. Geiger, and J. P. Spatz. Cell spreading and focal adhesion dynamics are regulated by spacing of integrin ligands. Biophys. J. 92:2964-2974, 2007. (Pubitemid 46557869)
    • (2007) Biophysical Journal , vol.92 , Issue.8 , pp. 2964-2974
    • Cavalcanti-Adam, E.A.1    Volberg, T.2    Micoulet, A.3    Kessler, H.4    Geiger, B.5    Spatz, J.P.6
  • 12
    • 33646831687 scopus 로고    scopus 로고
    • Non-slipping adhesive contact of an elastic cylinder on stretched substrates
    • Chen, S., and H. Gao. Non-slipping adhesive contact of an elastic cylinder on stretched substrates. Proc. R. Soc. A 462:211-228, 2006.
    • (2006) Proc. R. Soc. A , vol.462 , pp. 211-228
    • Chen, S.1    Gao, H.2
  • 13
    • 58049219023 scopus 로고    scopus 로고
    • Is cell rheology governed by nonequilibrium-to-equilibrium transition of noncovalent bonds?
    • Chowdhury, F., S. Na, O. Collin, B. Tay, F. Li, T. Tanaka, D. E. Leckband, and N. Wang. Is cell rheology governed by nonequilibrium-to- equilibrium transition of noncovalent bonds? Biophys. J. 95:5719-5727, 2008.
    • (2008) Biophys. J. , vol.95 , pp. 5719-5727
    • Chowdhury, F.1    Na, S.2    Collin, O.3    Tay, B.4    Li, F.5    Tanaka, T.6    Leckband, D.E.7    Wang, N.8
  • 15
    • 0035997133 scopus 로고    scopus 로고
    • Buckling of actin stress fibers: A new wrinkle in the cytoskeletal tapestry
    • DOI 10.1002/cm.10056
    • Costa, K. D., W. J. Hucker, and F. C. P. Yin. Buckling of actin stress fibers: A new wrinkle in the cytoskeletal tapestry. Cell Motil. Cytoskel. 52:266-274, 2002. (Pubitemid 34803846)
    • (2002) Cell Motility and the Cytoskeleton , vol.52 , Issue.4 , pp. 266-274
    • Costa, K.D.1    Hucker, W.J.2    Yin, F.C.-P.3
  • 16
    • 0022762304 scopus 로고
    • Orientation response of arterial smooth muscle cells to mechanical stimulation. Eur
    • Dartsch, P., and H. Hammerle. Orientation response of arterial smooth muscle cells to mechanical stimulation. Eur. J. Cell Biol. 41:339-346, 1986.
    • (1986) J. Cell Biol. , vol.41 , pp. 339-346
    • Dartsch, P.1    Hammerle, H.2
  • 17
    • 34548432555 scopus 로고    scopus 로고
    • Dynamics of cell orientation
    • De, R., A. Zemel, and S. A. Safran. Dynamics of cell orientation. Nat. Phys. 3:655-659, 2007.
    • (2007) Nat. Phys. , vol.3 , pp. 655-659
    • De, R.1    Zemel, A.2    Safran, S.A.3
  • 18
    • 33749077090 scopus 로고    scopus 로고
    • Tensile properties of single stress fibers isolated from cultured vascular smooth muscle cells
    • DOI 10.1016/j.jbiomech.2005.08.026, PII S002192900500401X
    • Deguchi, S., T. Ohashi, and M. Sato. Tensile properties of single stress fibers isolated from cultured vascular smooth muscle cells. J. Biomech. 39:2603-2610, 2006. (Pubitemid 44465922)
    • (2006) Journal of Biomechanics , vol.39 , Issue.14 , pp. 2603-2610
    • Deguchi, S.1    Ohashi, T.2    Sato, M.3
  • 19
    • 0031956985 scopus 로고    scopus 로고
    • Effect of precise mechanical loading on fibroblast populated collagen lattices: Morphological changes
    • DOI 10.1002/(SICI)1097-0169(1998)40:1<13::AID-CM2>3.0.CO;2-G
    • Eastwood, M., V. C. Mudera, D. A. McGrouther, and R. A. Brown. Effect of precise mechanical loading on fibroblast populated collagen lattices: Morphological changes. Cell Motil. Cytoskel. 40:13-21, 1998. (Pubitemid 28225538)
    • (1998) Cell Motility and the Cytoskeleton , vol.40 , Issue.1 , pp. 13-21
    • Eastwood, M.1    Mudera, V.C.2    McGrouther, D.A.3    Brown, R.A.4
  • 20
    • 85032428079 scopus 로고    scopus 로고
    • Stability of adhesion clusters under constant force
    • Erdmann, T., andU. S. Schwarz. Stabilityof adhesion clusters under constant force. Phys. Rev. Lett. 92:108102, 2004.
    • (2004) Phys. Rev. Lett. , vol.92 , pp. 108102
    • Erdmann, T.1    Schwarz, U.S.2
  • 21
    • 2342596964 scopus 로고    scopus 로고
    • Friction through dynamical formation and rupture of molecular bonds
    • Filippov, A. E., J. Klafter, and M. Urbakh. Friction through dynamical formation and rupture of molecular bonds. Phys. Rev. Lett. 92:135503, 2004.
    • (2004) Phys. Rev. Lett. , vol.92 , pp. 135503
    • Filippov, A.E.1    Klafter, J.2    Urbakh, M.3
  • 23
    • 0034925225 scopus 로고    scopus 로고
    • Invited review: Focal adhesion and small heat shock proteins in the regulation of actin remodeling and contractility in smooth muscle
    • Gerthoffer, W. T., and S. J. Gunst. Signal transduction in smooth muscle-invited review: Focal adhesion and small heat shock proteins in the regulation of actin remodeling and contractility in smooth muscle. J. Appl. Phys. 91:963-972, 2001. (Pubitemid 32681132)
    • (2001) Journal of Applied Physiology , vol.91 , Issue.2 , pp. 963-972
    • Gerthoffer, W.T.1    Gunst, S.J.2
  • 24
    • 30944452186 scopus 로고    scopus 로고
    • Focal adhesion size controls tension-dependent recruitment of α-smooth muscle actin to stress fibers
    • DOI 10.1083/jcb.200506179
    • Goffin, J. M., P. Pittet, G. Csucs, J. W. Lussi, J.-J. Meister, and B. Hinz. Focal adhesion size controls tension-dependent recruitment of {alpha}-smooth muscle actin to stress fibers. J. Cell Biol. 172:259-268, 2006. (Pubitemid 43112972)
    • (2006) Journal of Cell Biology , vol.172 , Issue.2 , pp. 259-268
    • Goffin, J.M.1    Pittet, P.2    Csucs, G.3    Lussi, J.W.4    Meister, J.-J.5    Hinz, B.6
  • 25
    • 0030056968 scopus 로고    scopus 로고
    • Cell adhesion: The molecular basis of tissue architecture and morphogenesis
    • DOI 10.1016/S0092-8674(00)81279-9
    • Gumbiner, B. M. Cell adhesion: The molecular basis of tissue architecture and morphogenesis. Cell 84:345-357, 1996. (Pubitemid 26058560)
    • (1996) Cell , vol.84 , Issue.3 , pp. 345-357
    • Gumbiner, B.M.1
  • 26
    • 0030053840 scopus 로고    scopus 로고
    • An elastic network model based on the structure of the red blood cell membrane skeleton
    • Hansen, J. C., R. Skalak, S. Chien, and A. Hoger. An elastic network model based on the structure of the red blood cell membrane skeleton. Biophys. J. 70:146-166, 1996. (Pubitemid 26021456)
    • (1996) Biophysical Journal , vol.70 , Issue.1 , pp. 146-166
    • Hansen, J.C.1    Skalak, R.2    Chien, S.3    Hoger, A.4
  • 27
    • 33646386142 scopus 로고    scopus 로고
    • Stress fibers are generated by two distinct actin assembly mechanisms in motile cells
    • Hotulainen, P., and P. Lappalainen. Stress fibers are generated by two distinct actin assembly mechanisms in motile cells. J. Cell Biol. 173:383-394, 2006.
    • (2006) J. Cell Biol. , vol.173 , pp. 383-394
    • Hotulainen, P.1    Lappalainen, P.2
  • 28
    • 63449134731 scopus 로고    scopus 로고
    • A dynamic stochastic model of frequency-dependent stress fiber alignment induced by cyclic stretch
    • Hsu, H. J., C. F. Lee, and R. Kaunas. A dynamic stochastic model of frequency-dependent stress fiber alignment induced by cyclic stretch. PLoS ONE 4(3):e4853, 2009.
    • (2009) PLoS ONE , vol.4 , Issue.3
    • Hsu, H.J.1    Lee, C.F.2    Kaunas, R.3
  • 29
    • 79952607988 scopus 로고    scopus 로고
    • Cell and molecular biomechanics: Perspectives and challenges
    • Ji, B., and G. Bao. Cell and molecular biomechanics: Perspectives and challenges. Acta Mechanica Solida Sinica 24:27-51, 2011.
    • (2011) Acta Mechanica Solida Sinica , vol.24 , pp. 27-51
    • Ji, B.1    Bao, G.2
  • 30
    • 79952582968 scopus 로고    scopus 로고
    • Dynamics of adhesion cluster and cell reorientation under lateral cyclic loading
    • Ji, B., D. Kong, and L. H. Dai. Dynamics of adhesion cluster and cell reorientation under lateral cyclic loading. Biorheology 45:96-97, 2008.
    • (2008) Biorheology , vol.45 , pp. 96-97
    • Ji, B.1    Kong, D.2    Dai, L.H.3
  • 31
    • 55949135876 scopus 로고    scopus 로고
    • Two characteristic regimes in frequency-dependent dynamic reorientation of fibroblasts on cyclically stretched substrates
    • Jungbauer, S., H. Gao, J. P. Spatz, and R. Kemkemer. Two characteristic regimes in frequency-dependent dynamic reorientation of fibroblasts on cyclically stretched substrates. Biophys. J. 95:3470-3478, 2008.
    • (2008) Biophys. J. , vol.95 , pp. 3470-3478
    • Jungbauer, S.1    Gao, H.2    Spatz, J.P.3    Kemkemer, R.4
  • 32
    • 60449089873 scopus 로고    scopus 로고
    • A kinematic model of stretchinduced stress fiber turnover and reorientation
    • Kaunas, R., and H.-J. Hsu. A kinematic model of stretchinduced stress fiber turnover and reorientation. J. Theor. Biol. 257:320-330, 2009.
    • (2009) J. Theor. Biol. , vol.257 , pp. 320-330
    • Kaunas, R.1    Hsu, H.-J.2
  • 33
    • 77951652475 scopus 로고    scopus 로고
    • A kinematic model coupling stress fiber dynamics with JNK activation in response to matrix stretching
    • Kaunas, R., Z. Y. Huang, and J. Hahn. A kinematic model coupling stress fiber dynamics with JNK activation in response to matrix stretching. J. Theor. Biol. 264:593-603, 2010.
    • (2010) J. Theor. Biol. , vol.264 , pp. 593-603
    • Kaunas, R.1    Huang, Z.Y.2    Hahn, J.3
  • 35
    • 67649598285 scopus 로고    scopus 로고
    • Demonstration of catch bonds between an integrin and its ligand
    • Kong, F., A. J. Garcia, A. P. Mould, M. J. Humphries, and C. Zhu. Demonstration of catch bonds between an integrin and its ligand. J. Cell Biol. 185:1275-1284, 2009.
    • (2009) J. Cell Biol. , vol.185 , pp. 1275-1284
    • Kong, F.1    Garcia, A.J.2    Mould, A.P.3    Humphries, M.J.4    Zhu, C.5
  • 36
    • 56049121940 scopus 로고    scopus 로고
    • Stability of adhesion clusters and cell reorientation under lateral cyclic tension
    • Kong, D., B. Ji, and L. Dai. Stability of adhesion clusters and cell reorientation under lateral cyclic tension. Biophys. J. 95:4034-4044, 2008.
    • (2008) Biophys. J. , vol.95 , pp. 4034-4044
    • Kong, D.1    Ji, B.2    Dai, L.3
  • 37
    • 36348989658 scopus 로고    scopus 로고
    • Nonlinear mechanical modeling of cell adhesion
    • DOI 10.1016/j.jtbi.2007.09.028, PII S0022519307004560
    • Kong, D., B. Ji, and L. Dai. Nonlinear mechanical modeling of cell adhesion. J. Theor. Biol. 250:75-84, 2008. (Pubitemid 350160716)
    • (2008) Journal of Theoretical Biology , vol.250 , Issue.1 , pp. 75-84
    • Kong, D.1    Ji, B.2    Dai, L.3
  • 38
    • 77956408762 scopus 로고    scopus 로고
    • Stabilizing to disruptive transition of focal adhesion response to mechanical forces
    • Kong, D., B. H. Ji, and L. H. Dai. Stabilizing to disruptive transition of focal adhesion response to mechanical forces. J. Biomech. 43:2524-2529, 2010.
    • (2010) J. Biomech. , vol.43 , pp. 2524-2529
    • Kong, D.1    Ji, B.H.2    Dai, L.H.3
  • 39
    • 16344382436 scopus 로고    scopus 로고
    • A semianalytic model of leukocyte rolling
    • DOI 10.1529/biophysj.104.039693
    • Krasik, E. F., and D. A. Hammer. A semianalytic model of leukocyte rolling. Biophys. J. 87:2919-2930, 2004. (Pubitemid 40468553)
    • (2004) Biophysical Journal , vol.87 , Issue.5 , pp. 2919-2930
    • Krasik, E.F.1    Hammer, D.A.2
  • 40
    • 33646179573 scopus 로고    scopus 로고
    • Viscoelastic retraction of single living stress fibers and its impact on cell shape, cytoskeletal organization, and extracellular matrix mechanics
    • Kumar, S., I. Z. Maxwell, A. Heisterkamp, T. R. Polte, T. P. Lele, M. Salanga, E. Mazur, and D. E. Ingber. Viscoelastic retraction of single living stress fibers and its impact on cell shape, cytoskeletal organization, and extracellular matrix mechanics. Biophys. J. 90:3762-3773, 2006.
    • (2006) Biophys. J. , vol.90 , pp. 3762-3773
    • Kumar, S.1    Maxwell, I.Z.2    Heisterkamp, A.3    Polte, T.R.4    Lele, T.P.5    Salanga, M.6    Mazur, E.7    Ingber, D.E.8
  • 42
    • 0025854524 scopus 로고
    • Leukocytes roll on a selectin at physiologic flow rates: Distinction from and prerequisite for adhesion through integrins
    • Lawrence, M. B., and T. A. Springer. Leukocytes roll on a selectin at physiologic flow rates: Distinction from and prerequisite for adhesion through integrins. Cell 65:859-873, 1991. (Pubitemid 121001317)
    • (1991) Cell , vol.65 , Issue.5 , pp. 859-873
    • Lawrence, M.B.1    Springer, T.A.2
  • 43
    • 77958153094 scopus 로고    scopus 로고
    • Cyclic stretch-induced stress fiber dynamics-dependence on strain rate, Rho-kinase and MLCK
    • Lee, C. F., C. Haase, S. Deguchi, and R. Kaunas. Cyclic stretch-induced stress fiber dynamics-dependence on strain rate, Rho-kinase and MLCK. Biochem. Biophys. Res. Commun. 401:344-349, 2010.
    • (2010) Biochem. Biophys. Res. Commun. , vol.401 , pp. 344-349
    • Lee, C.F.1    Haase, C.2    Deguchi, S.3    Kaunas, R.4
  • 44
    • 38949204963 scopus 로고    scopus 로고
    • Role of cyclic strain frequency in regulating the alignment of vascular smooth muscle cells in vitro
    • Liu, B., M.-J. Qu, K.-R. Qin, H. Li, Z.-K. Li, B.-R. Shen, and Z.-L. Jiang. Role of cyclic strain frequency in regulating the alignment of vascular smooth muscle cells in vitro. Biophys. J. 94:1497-1507, 2008.
    • (2008) Biophys. J. , vol.94 , pp. 1497-1507
    • Liu, B.1    Qu, M.-J.2    Qin, K.-R.3    Li, H.4    Li, Z.-K.5    Shen, B.-R.6    Jiang, Z.-L.7
  • 46
    • 0037653696 scopus 로고    scopus 로고
    • Direct observation of catch bonds involving cell-adhesion molecules
    • DOI 10.1038/nature01605
    • Marshall, B. T., M. Long, J. W. Piper, T. Yago, R. P. McEver, and C. Zhu. Direct observation of catch bonds involving cell-adhesion molecules. Nature 423:190-193, 2003. (Pubitemid 36569544)
    • (2003) Nature , vol.423 , Issue.6936 , pp. 190-193
    • Marshall, B.T.1    Long, M.2    Piper, J.W.3    Yago, T.4    McEver, R.P.5    Zhu, C.6
  • 47
    • 77951880862 scopus 로고    scopus 로고
    • Actin stress fibers are at a tipping point between conventional shortening and rapid disassembly at physiological levels of MgATP
    • Matsui, T. S., K. Ito, R. Kaunas, M. Sato, and S. Deguchi. Actin stress fibers are at a tipping point between conventional shortening and rapid disassembly at physiological levels of MgATP. Biochem. Biophys. Res. Commun. 395: 301-306, 2010.
    • (2010) Biochem. Biophys. Res. Commun. , vol.395 , pp. 301-306
    • Matsui, T.S.1    Ito, K.2    Kaunas, R.3    Sato, M.4    Deguchi, S.5
  • 48
    • 0028273039 scopus 로고
    • Cyclic stretching of human osteoblasts affects proliferation and metabolism: A new experimental method and its application
    • Neidlinger-Wilke, C., H. J. Wilke, and L. Claes. Cyclic stretching of human osteoblasts affects proliferation and metabolism-A new experimental-method and its application. J. Orthopaed. Res. 12:70-78, 1994. (Pubitemid 24070790)
    • (1994) Journal of Orthopaedic Research , vol.12 , Issue.1 , pp. 70-78
    • Neidlinger-Wilke, C.1    Wilke, H.-J.2    Claes, L.3
  • 49
    • 38949136411 scopus 로고    scopus 로고
    • Propagation of mechanical stress through the actin cytoskeleton toward focal adhesions: Model and experiment
    • Paul, R., P. Heil, J. P. Spatz, and U. S. Schwarz. Propagation of mechanical stress through the actin cytoskeleton toward focal adhesions: Model and experiment. Biophys. J. 94:1470-1482, 2008.
    • (2008) Biophys. J. , vol.94 , pp. 1470-1482
    • Paul, R.1    Heil, P.2    Spatz, J.P.3    Schwarz, U.S.4
  • 51
    • 0347949622 scopus 로고    scopus 로고
    • The Molecular Mechanics of P- and L-Selectin Lectin Domains Binding to PSGL-1
    • Rinko, L. J., M. B. Lawrence, and W. H. Guilford. The molecular mechanics of P-and L-selectin lectin domains binding to PSGL-1. Biophys. J. 86:544-554, 2004. (Pubitemid 38067484)
    • (2004) Biophysical Journal , vol.86 , Issue.1 , pp. 544-554
    • Rinko, L.J.1    Lawrence, M.B.2    Guilford, W.H.3
  • 52
    • 0035844869 scopus 로고    scopus 로고
    • Focal contacts as mechanosensors: Externally applied local mechanical force induces growth of focal contacts by an mDia1-dependent and ROCK-independent mechanism
    • Riveline, D., E. Zamir, N. Q. Balaban, U. S. Schwarz, T. Ishizaki, S. Narumiya, Z. Kam, B. Geiger, and A. D. Bershadsky. Focal contacts as mechanosensors: Externally applied local mechanical force induces growth of focal contacts by an mDia1-dependent and ROCK-independent mechanism. J. Cell Biol. 153:1175-1186, 2001.
    • (2001) J. Cell Biol. , vol.153 , pp. 1175-1186
    • Riveline, D.1    Zamir, E.2    Balaban, N.Q.3    Schwarz, U.S.4    Ishizaki, T.5    Narumiya, S.6    Kam, Z.7    Geiger, B.8    Bershadsky, A.D.9
  • 53
    • 0034715923 scopus 로고    scopus 로고
    • Focal adhesions: A nexus for intracellular signaling and cytoskeletal dynamics
    • Sastry, S. K., and K. Burridge. Focal adhesions: A nexus for intracellular signaling and cytoskeletal dynamics. Exp. Cell Res. 261:25-36, 2000.
    • (2000) Exp. Cell Res. , vol.261 , pp. 25-36
    • Sastry, S.K.1    Burridge, K.2
  • 54
    • 8944235343 scopus 로고    scopus 로고
    • Theoretical estimates of mechanical properties of the endothelial cell cytoskeleton
    • Satcher, R. L., and C. F. Dewey. Theoretical estimates of mechanical properties of the endothelial cell cytoskeleton. Biophys. J. 71:109-118, 1996.
    • (1996) Biophys. J. , vol.71 , pp. 109-118
    • Satcher, R.L.1    Dewey, C.F.2
  • 56
    • 0034759733 scopus 로고    scopus 로고
    • Specificity of endothelial cell reorientation in response to cyclic mechanical stretching
    • DOI 10.1016/S0021-9290(01)00150-6, PII S0021929001001506
    • Wang, J. H. C., P. Goldschmidt-Clermont, J. Wille, and F. C. P. Yin. Specificity of endothelial cell reorientation in response to cyclic mechanical stretching. J. Biomech. 34:1563-1572, 2001. (Pubitemid 33041372)
    • (2001) Journal of Biomechanics , vol.34 , Issue.12 , pp. 1563-1572
    • Wang, J.H.-C.1    Goldschmidt-Clermont, P.2    Wille, J.3    Yin, F.C.-P.4
  • 57
    • 0029612290 scopus 로고
    • Cell orientation response to cyclically deformed substrates: Experimental validation of a cell model
    • DOI 10.1016/0021-9290(95)00101-8
    • Wang, H. C., W. Ip, R. Boissy, and E. S. Grood. Cell orientation response to cyclically deformed substrates: Experimental validation of a cell model. J. Biomech. 28:1543-1552, 1995. (Pubitemid 26004299)
    • (1995) Journal of Biomechanics , vol.28 , Issue.12 , pp. 1543-1552
    • Wang, H.1    Ip, W.2    Boissy, R.3    Grood, E.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.