Does Variance in Drinking Motives Explain the Genetic Overlap Between Personality and Alcohol Use Disorder Symptoms? A Twin Study of Young Women

Alcoholism: Clinical and Experimental Research

Volumn 35, Issue 12, 2011, Pages 2242-2250

  Littlefield, Andrew K ^a   Agrawal, Arpana ^b   Ellingson, Jarrod M ^a   Kristjansson, Sean ^b   Madden, Pamela A F ^b   Bucholz, Kathleen K ^b   Slutske, Wendy S ^a   Heath, Andrew C ^b   Sher, Kenneth J ^a  

^a Midwest Alcoholism Research Institute   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alcohol Use Disorders; Behavior Genetics; Drinking Motives; Personality

Indexed keywords

ADULT; AGREEABLENESS; ALCOHOL CONSUMPTION; ALCOHOLISM; ARTICLE; CONSCIENTIOUSNESS; COPING BEHAVIOR; DRINKING BEHAVIOR; DRINKING MOTIVE QUESTIONNAIRE; FEMALE; GENETIC ASSOCIATION; GENETIC VARIABILITY; HEREDITY; HUMAN; MOTIVATION; MULTIDIMENSIONAL PERSONALITY QUESTIONNAIRE; NEO PERSONALITY INVENTORY; NEUROSIS; PERSONALITY; PERSONALITY TEST; PHENOTYPE; PRIORITY JOURNAL; QUESTIONNAIRE; SYMPTOMATOLOGY; TWINS;

ADOLESCENT; ADULT; ALCOHOL DRINKING; ALCOHOLISM; FEMALE; HUMANS; MOTIVATION; PERSONALITY; QUESTIONNAIRES; TWINS; YOUNG ADULT;

EID: 81855176021     PISSN: 01456008     EISSN: 15300277     Source Type: Journal    
DOI: 10.1111/j.1530-0277.2011.01574.x     Document Type: Article

References (81)

1. Agrawal A, Dick DM, Bucholz KK, Madden PAF, Cooper ML, Sher KJ, Heath AC (2008) Drinking expectancies and motives: a genetic study of young adult women. Addiction 103:194-204.
2. Agrawal A, Jacobson KC, Prescott CA, Kendler KS (2004) A twin study of personality and illicit drug use and abuse/dependence. Twin Research 7:72-81.
3. American Psychiatric Association (1994) Diagnostic and Statistical Manual of Mental Disorders. 4th ed. Author, Washington DC.
4. Arnett JJ (2000) Emerging adulthood: a theory of development from the late teens through the twenties. Am Psychol 55:469-480.
5. Bucholz KK, Cadoret R, Cloninger CR, Dinwiddie SH, Hesselbrock VM, Nurnberger JI Jr, Reich T, Schmidt I, Schuckit MA (1994) A new semi-structured psychiatric interview for use in genetic linkage studies: a report on the reliability of the SSAGA. J Stud Alcohol 55:149-158.
6. Carey KB (1993) Situational determinants of heavy drinking among college students. J Couns Psychol 40:217-220.
7. Carpenter KM, Hasin DS (1999) Drinking to cope with negative affect and DSM-IV alcohol use disorders: a test of three alternative explanations. J Stud Alcohol 60:694-704.
8. Cloninger CR (1987) Neurogenetic adaptive mechanisms in alcoholism. Science 236:410-416.
9. Cloninger CR, Przybeck TR, Svrakic DM (1991) The Tridimensional Personality Questionnaire: U.S. normative data. Psychol Rep 69:1047-1057.
10. Cohen J (1977) Statistical Power Analysis for the Behavioral Sciences (revised ed). Academic Press, New York.
11. Colder CR, O'Connor R (2002) Attention biases and disinhibited behavior as predictors of alcohol use and enhancement reasons for drinking. Psychol Addict Behav 16:325-332.
12. Comeau MN, Stewart SH, Loba P (2001) The relations of anxiety sensitivity, trait anxiety, and sensation seeking to adolescents' motivations for alcohol, cigarette, and marijuana use. Addict Behav 26:803-825.
13. Cooper ML (1994) Motivations for alcohol use among adolescents: development and validation of a four-factor-model. Psychol Assess 6:117-128.
14. Cooper ML, Agocha VB, Sheldon MS (2000) A motivational perspective on risky behaviors: the role of personality and affect regulatory processes. J Pers 68:1059-1088.
15. Cooper ML, Frone MR, Russell M, Mudar P (1995) Drinking to regulate positive and negative emotions: a motivational model of alcohol use. J Pers Soc Psychol 69:990-1005.
16. Cooper ML, Krull JL, Agocha VB, Flanagan ME, Orcutt HK, Grabe SD, Kurt H, Jackson M (2008) Motivational pathways to alcohol use and abuse among Black and White adolescents. J Abnorm Psychol 117:485-501.
17. Cooper ML, Russell M, George WH (1988) Coping, expectancies, and alcohol abuse: a test of social learning formulations. J Abnorm Psychol 92:218-230.
18. Cooper ML, Russell M, Skinner JB, Windle M (1992) Development and validation of a three-dimensional measure of drinking motives. Psychol Assess 4:123-132.
19. Costa PT Jr, McCrae RR (1985) The NEO Personality Inventory Manual. Psychological Assessment Resources, Odessa, FL.
20. Cox WM, Klinger E (1988) A motivational model of alcohol use. J Abnorm Psychol 97:168-180.
21. Cox WM, Blount JP, Klinger E (1990). Incentive motivation, affective change, and alcohol use: a model, in Why People Drink: Parameters of Alcohol as a Reinforcer (Cox WM ed), pp. 291-314. Gardner, New York.
22. De Pauw SS, Mervielde I (2010) Temperament, personality and developmental psychopathology: a review based on the conceptual dimensions underlying childhood traits. Child Psychiatry Hum Dev 41:313-329.
23. Eaves LJ, Last KA, Young PA, Martin NG (1978) Model-fitting approaches to the analysis of human behavior. Heredity 41:249-320.
24. Eysenck HJ, Eysenck SBG, Barrett P (1985) A revised version of the Psychoticism scale. Personality Individ Differ 6:21-29.
25. Fanous A, Gardner CO, Prescott CA, Cancro R, Kendler KS (2002) Neuroticism, major depression and gender: a population-based twin study. Psychol Med 32:719-728.
26. Gottesman II (1963) Heritability of personality. Psychological Monographs 77(9, Whole No. 572):1-21.
27. Grant VV, Stewart SH, O'Connor RM, Blackwell E, Conrod PJ (2007) Psychometric evaluation of the five-factor Modified Drinking Motives Questionnaire-Revised in undergraduates. Addict Behav 32:2611-2632.
28. Heath AC, Howells W, Bucholz KK, Glowinski AL, Nelson EC, Madden PA (2002) Ascertainment of amid-western US female adolescent twin cohort for alcohol studies: assessment of sample representativeness using birth record data. Twin Research 5:107-112.
29. Heath AC, Madden PA, Grant JD, McLaughlin TL, Todorov AA, Bucholz KK (1999) Resiliency factors protecting against teenage alcohol use and smoking: influences of religion, religious involvement and values, and ethnicity in the Missouri Adolescent Female Twin Study. Twin Research 2:145-155.
30. Hesselbrock M, Easton C, Bucholz KK, Schuckit M, Hesselbrock V (1999) A validity study of the SSAGA-A comparison with the SCAN. Addiction 9:1361-1370.
31. Holahan CJ, Moos RH, Holahan CK, Cronkite RC, Randall PK (2001) Drinking to cope, emotional distress and alcohol use and abuse: a ten-year model. J Stud Alcohol 62:190-198.
32. Holahan CJ, Moos RH, Holahan CK, Cronkite RC, Randall PK (2003) Drinking to cope and alcohol use and abuse in unipolar depression: a 10-year model. J Abnorm Psychol 112:159-165.
33. Jinks JL, Fulker DW (1970) Comparison of the biometrical genetical, MAVA, and classical approaches to the analysis of human behavior. Psychol Bull 73:311-349.
34. Keller MC, Medland SE, Duncan LE (2009) Are extended twin family designs worth the trouble? A comparison of the bias, precision, and accuracy of parameters estimated in four twin family models. Behav Genet 12:8-18.
35. Kendler KS, Gatz M, Gardner CO, Pedersen NL (2006) Personality and major depression: a Swedish longitudinal, population-based twin study. Arch Gen Psychiatry 63:1113-1120.
36. Kendler KS, Kessler RC, Neale MC, Heath AC, Eaves LJ (1993) The prediction of major depression in women: toward an integrated etiologic model. Am J Psychiatry 150:1139-1148.
37. Kendler KS, Myers JM, Prescott CA (2007) The specificity of genetic and environmental risk factors for symptoms of cannabis, cocaine, alcohol, caffeine and nicotine dependence. Arch Gen Psychiatry 64:1313-1320.
38. Knopik VS, Sparrow EP, Madden PA, Bucholz KK, Hudziak J, Reich W, Slutske WS, Grant JD, McLaughlin TL, Todorov A, Todd RD, Heath AC (2005) Contributions of parental alcoholism, prenatal substance exposure, and genetic transmission to child ADHD risk: a female twin study. Psychol Med 35:625-635.
39. Kristjansson SD, Agrawal A, Littlefield AK, Pergadia ML, Lessov-Schlaggar CN, Sartor CE, Bucholz KK, Madden PA, Cooper ML, Sher KJ, Heath AC (2011) Drinking motives in female smokers: factor structure, alcohol dependence, and genetic influences. Alcohol Clin Exp Res 35:345-354.
40. Kuntsche E, Knibbe R, Gmel G, Engels R (2006) Who drinks and why? A review of socio-demographic, personality, and contextual issues behind the drinking motives in young people. Addict Behav 31:1844-1857.
41. Kuntsche E, von Fischer M, Gmel G (2008) Personality factors and alcohol use: a mediator analysis of drinking motives. Personality Individ Differ 8:796-800.
42. Kuntsche EN, Knibbe R, Gmel G, Engels R (2005) Why do young people drink? A review of drinking motives. Clin Psychol Rev 25:841-861.
43. Lahey BB (2009) Public health significance of neuroticism. Am Psychol 64:241-256.
44. Littlefield AK, Sher KJ (2010). The multiple, distinct ways that personality contributes to alcohol use disorders. Soc Personal Psychol Compass 4:767-782.
45. Littlefield AK, Sher KJ, Steinley D (2010a) Developmental trajectories of impulsivity and their association with alcohol use and related outcomes during emerging and young adulthood I. Alcohol Clin Exp Res 34:1409-1416.
46. Littlefield AK, Sher KJ, Wood PK (2009) Is the "maturing out" of problematic alcohol involvement related to personality change? J Abnorm Psychol 118:360-374.
47. Littlefield A, Sher KJ, Wood PK (2010b) Do changes in drinking motives mediate the relation between personality change and "maturing out" of problem drinking?" J Abnorm Psychol 119:93-105.
48. Littlefield AK, Sher KJ, Wood PK (2010c) A personality-based description of maturing out of alcohol problems: extension with a five-factor model and robustness to modeling challenges. Addict Behav 35:948-954.
49. Lotrich FE, Pollock BG (2004) Meta-analysis of serotonin transporter polymorphisms and affective disorders. Psychiatr Genet 14:121-129.
50. Loukas A, Krull J, Chassin L, Carle A (2000) The relation of personality to alcohol abuse/dependence in a high-risk sample. J Pers 68:1153-1175.
51. Malouff JM, Thorsteinsson EB, Rooke SE, Schutte NS (2007) Alcohol involvement and the five-factor model of personality: a meta-analysis. J Drug Educ 37:277-294.
52. Markou A, Kosten TR, Koob GF (1998) Neurobiological similarities in depression and drug dependence: A self medication hypothesis. Neuropsychopharmacology 18:135-174.
53. McNally AM, Palfai TP, Levine RV, Moore BM (2003) Attachment dimensions and drinking-related problems among young adults. The mediational role of coping motives. Addict Behav 28:1115-1127.
54. Morton NE (1974) Analysis of family resemblance. I. Introduction. Am J Hum Genet 26:318-330.
55. Muthén LK, Muthén BO (2010) Mplus User's Guide [Computer software and manual]. 6th ed. Muthén & Muthén, Los Angeles.
56. Neale MC, Maes HHM (2002) Methodology for Genetic Studies of Twins and Families. Kluwer Academic Publishers, Dordrecht.
57. Nellissery M, Feinn RS, Covault J, Gelernter J, Anton RF, Pettinati H, Moak D, Mueller T, Kranzler HR (2003) Alleles of a functional serotonin transporter promoter polymorphism are associated with major depression in alcoholics. Alcohol Clin Exp Res 27:1402-1408.
58. Prescott CA, Cross RJ, Kuhn JW, Horn JL, Kendler KS (2004) Is risk for alcoholism mediated by individual differences in drinking motivations? Alcohol Clin Exp Res 28:29-39.
59. Prescott CA, Maes HH, Kendler KS (2005) Genetics of substance use disorders, in Psychiatric Genetics, Review of Psychiatry, Vol. 24 (Kendler KS, Eaves LJ eds), pp 167-196 American Psychiatric Publishing Inc, Washington, DC.
60. Rao DC, Morton NE, Yee S (1974) Analysis of family resemblance. II. A linear model for familial correlation. Am J Hum Genet 26:331-359.
61. Rao U (2006) Links between depression and substance abuse in adolescents. Am J Prev Med 31:S161-S174.
62. Read JP, Wood MD, Kahler CW, Maddock JE, Palfai T (2003) Examining the role of drinking motives in college student alcohol use and problems. Psychol Addict Behav 17:13-23.
63. Samochowiec J, Kucharska-Mazur J, Grzywacz A, Jablonski M, Rommelspacher H, Samochowiec A, Sznabowicz M, Horodnicki J, Sagan L, Pelka-Wysiecka J (2006) Family-based and case-control study of DRD2, DAT, 5HTT, COMT genes polymorphisms in alcohol dependence. Neurosci Lett 410:1-5.
64. Satorra A, Bentler PM (1994) Corrections to test statistics and standard errors in covariance structure analysis, in Latent Variable Analysis: Applications for Developmental Research (von Eye A, Clogg CC eds), pp 399-419. Sage, Thousand Oaks, CA.
65. Scarr S (1968) Environmental bias in twin studies. Eugen Q 15(1):34-40.
66. Schuckit MA, Smith TL (1996) An 8-year follow-up of 450 sons of alcoholic and control subjects. Arch Gen Psychiatry 53:202-210.
67. Schulenberg J, Wadsworth KN, O'Malley PM, Bachman JG, Johnston LD (1996) Adolescent risk factors for binge drinking during the transition to young adulthood: variable- and pattern-centered approaches to change. Dev Psychol 32:659-674.
68. Sher KJ, Grekin E, Williams N (2005) The development of alcohol problems. Annu Rev Clin Psychol 1:493-523.
69. Sher KJ, Trull TJ, Bartholow B, Vieth A (1999) Personality and alcoholism: issues, methods, and etiological processes, in Psychological Theories of Drinking and Alcoholism, 2nd ed (Blane H, Leonard K eds), pp 55-105. Plenum, New York.
70. Sher KJ, Walitzer KS, Wood P, Brent EE (1991) Characteristics of children of alcoholics: putative risk factors, substance use and abuse, and psychopathology. J Abnorm Psychol 100:427-448.
71. Shifman S, Bhomra A, Smiley S, Wray NR, James MR et al. (2007) A whole genome association study of neuroticism using DNA pooling. Mol Psychiatry 13:1-11.
72. Simons J, Correia CJ, Carey KB (2000) A comparison of motives for marijuana and alcohol use among experienced users. Addict Behav 25:153-160.
73. Slutske WS, Heath AC, Madden PAF, Bucholz KK, Statham D, Martin NG (2002) Personality and the genetic risk for alcohol dependence. J Abnorm Psychol 111:124-133.
74. Slutske WS, Hunt-Carter EE, Nabors-Oberg RE, Sher KJ, Bucholz KK, Madden PAF, Anokhin A, Heath AC (2004) Do college students drink more than their non-college-attending peers? Evidence from a population-based longitudinal female twin study. J Abnorm Psychol 113:530-540.
75. Stewart SH, Devine H (2000) Relations between personality and drinking motives in young adults. Personality Individ Differ 29:495-511.
76. Stewart SH, Loughlin HL, Rhyno E (2001) Internal drinking motives mediate personality domain-drinking relations in young adults. Personality Individ Differ 30:271-286.
77. Terracciano A, Sanna S, Uda M, Deiana B, Usala G, Busonero F, Maschio A, Scally M, Patriciu N, Chen WM (2008) Genome-wide association scan for five major dimensions of personality. Mol Psychiatry 15:647-656.
78. Theakston JA, Stewart SH, Dawson MY, Knowlden-Loewen SAB, Lehman DR (2004) Big-Five personality domains predict drinking motives. Personality Individ Differ 5:971-984.
79. Trull TJ, Waudby C, Sher KJ (2004) Alcoholism and personality disorder symptoms. Exp Clin Psychopharmacol 12:65-75.
80. Windle M, Windle RC (1996) Coping strategies, drinking motives, and stressful life events among middle adolescents: associations with emotional and behavioral problems and with academic functioning. J Abnorm Psychol 105:551-560.
81. Young-Wolff KC, Kendler KS, Sintov ND, Prescott CA (2009) Mood-related drinking motives mediate the familial association between major depression and alcohol dependence. Alcohol Clin Exp Res 33:1476-1486.