Prevention of FGF-2-induced angiogenesis by scopoletin, a coumarin compound isolated from Erycibe obtusifolia Benth, and its mechanism of action

International Immunopharmacology

Volumn 11, Issue 12, 2011, Pages 2007-2016

  Pan, Rong ^a   Gao, Xinghua ^a   Lu, Dan ^a   Xu, Xianxiang ^a   Xia, Yufeng ^a   Dai, Yue ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Angiogenesis; FGF 2; Human umbilical vein endothelial cells; Scopoletin; VEGF

Indexed keywords

COUMARIN DERIVATIVE; FIBROBLAST GROWTH FACTOR 2; SCOPOLETIN;

ANGIOGENESIS; ANTIANGIOGENIC ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; DOWN REGULATION; DRUG INHIBITION; DRUG MECHANISM; ERYCIBE OBSTUSIFOLIA; FEMALE; HUMAN; HUMAN CELL; MEDICINAL PLANT; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANGIOGENESIS INHIBITORS; ANIMALS; AORTA, THORACIC; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; DOWN-REGULATION; FIBROBLAST GROWTH FACTOR 2; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; I-KAPPA B KINASE; I-KAPPA B PROTEINS; MALE; NEOVASCULARIZATION, PATHOLOGIC; NF-KAPPA B; PHOSPHORYLATION; RATS; SCOPOLETIN; SIGNAL TRANSDUCTION; TREATMENT OUTCOME; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 81855164715     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2011.08.012     Document Type: Article

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