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Volumn 30, Issue 6, 1998, Pages 1115-1128

Effects of levosimendan on myocardial contractility and Ca2+ transients in aequorin-loaded right-ventricular papillary muscles and indo-1-loaded single ventricular cardiomyocytes of the rabbit

Author keywords

Aequorin; Ca2+ sensitizer; Carbachol; Indo 1; Levosimendan; Phosphodiesterase inhibitor; Rabbit, papillary muscle; Single ventricular cardiomyocyte

Indexed keywords

AEQUORIN; CALCIUM ION; CARBACHOL; INDO 1; LEVOSIMENDAN;

EID: 0032104314     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.1998.0677     Document Type: Article
Times cited : (74)

References (45)
  • 2
    • 0022637448 scopus 로고
    • 2+ as an inotropic mechanism
    • 2+ as an inotropic mechanism. Circulation 73 (Suppl. III): III-85-III-98.
    • (1986) Circulation , vol.73 , Issue.SUPPL. III
    • Blinks, J.R.1    Endoh, M.2
  • 3
    • 77957002889 scopus 로고
    • Practical aspects of the use of acquorin as a calcium indicator: Assay, preparation, microinjection, and interpretation of signals
    • BLINKS JR, MATTINGLY PH, JEWELL BR, VAN LEEUWEN M, HARRER GC, ALLEN DG, 1978. Practical aspects of the use of acquorin as a calcium indicator: assay, preparation, microinjection, and interpretation of signals. Methods Enzymol 57: 292-328.
    • (1978) Methods Enzymol , vol.57 , pp. 292-328
    • Blinks, J.R.1    Mattingly, P.H.2    Jewell, B.R.3    Van Leeuwen, M.4    Harrer, G.C.5    Allen, D.G.6
  • 4
    • 0025982134 scopus 로고
    • Contribution of cAMP-phosphodiesterase inhibition and sensitization of the contractile proteins for calcium to the inotropic effect of pimobendan in the failing human myocardium
    • BÖHM M, MORANO I, PIESKE B, RÜEGG JC, WANKERL M, ZIMMERMANN R, ERDMANN E, 1991. Contribution of cAMP-phosphodiesterase inhibition and sensitization of the contractile proteins for calcium to the inotropic effect of pimobendan in the failing human myocardium. Circ Res 68: 689-701.
    • (1991) Circ Res , vol.68 , pp. 689-701
    • Böhm, M.1    Morano, I.2    Pieske, B.3    Rüegg, J.C.4    Wankerl, M.5    Zimmermann, R.6    Erdmann, E.7
  • 7
    • 0024511994 scopus 로고
    • A comparison of oral milrinone, digoxin, and their combination in the treatment of patients with chronic heart failure
    • DIBIANCO R, SHABETAI R, KOSTUK W, MORAN J, SCHLANT RC, WRIGHT R, MILRINONE MULTICENTER TRIAL GROUP, 1989. A comparison of oral milrinone, digoxin, and their combination in the treatment of patients with chronic heart failure. N Engl J Med 320: 677-683.
    • (1989) N Engl J Med , vol.320 , pp. 677-683
    • Dibianco, R.1    Shabetai, R.2    Kostuk, W.3    Moran, J.4    Schlant, R.C.5    Wright, R.6
  • 8
    • 0028038962 scopus 로고
    • f) by cAMP in the rabbit sino-atrial node
    • f) by cAMP in the rabbit sino-atrial node. J Physiol 474: 473-482.
    • (1994) J Physiol , vol.474 , pp. 473-482
    • Difrancesco, D.1    Mangoni, M.2
  • 10
    • 0002569404 scopus 로고
    • Characteristics of regulation of intracellular calcium mobilization and sensitivity by β-adrenoceptor and muscarinic agonists, and a novel inotropic agent, MCI-154, in canine ventricular myocardium
    • Yamada K, Shibata S, Katz AM and Fabiato F (eds). New York: Pergamon Press
    • ENDOH M, 1990. Characteristics of regulation of intracellular calcium mobilization and sensitivity by β-adrenoceptor and muscarinic agonists, and a novel inotropic agent, MCI-154, in canine ventricular myocardium. In: Yamada K, Shibata S, Katz AM and Fabiato F (eds). Recent Advances in Ca Channels and Ca-antagonists. New York: Pergamon Press, 51-59.
    • (1990) Recent Advances in Ca Channels and Ca-antagonists , pp. 51-59
    • Endoh, M.1
  • 11
    • 0028819318 scopus 로고
    • The effects of various drugs on the myocardial inotropic response
    • ENDOH M, 1995. The effects of various drugs on the myocardial inotropic response. Gen Pharmacol 262: 1-31.
    • (1995) Gen Pharmacol , vol.262 , pp. 1-31
    • Endoh, M.1
  • 12
    • 0023880317 scopus 로고
    • 2+ mediated through α- and β-adrenoceptors
    • 2+ mediated through α- and β-adrenoceptors. Circ Res 62: 247-265.
    • (1988) Circ Res , vol.62 , pp. 247-265
    • Endoh, M.1    Blinks, J.R.2
  • 13
    • 0018735239 scopus 로고
    • Differentiation by cholinergic stimulation of positive inotropic actions mediated via α- and β-adrenoceptors in the rabbit heart
    • ENDOH M, MOTOMURA S, 1979. Differentiation by cholinergic stimulation of positive inotropic actions mediated via α- and β-adrenoceptors in the rabbit heart. Life Sci 25: 759-768.
    • (1979) Life Sci , vol.25 , pp. 759-768
    • Endoh, M.1    Motomura, S.2
  • 15
    • 0010620718 scopus 로고    scopus 로고
    • 2+ sensitivity in rabbit single ventricular cardiomyocytes loaded with indo-1/AM: Comparison with the effects of phenylephrine and angiotensin II
    • 2+ sensitivity in rabbit single ventricular cardiomyocytes loaded with indo-1/AM: comparison with the effects of phenylephrine and angiotensin II. J Cardiac Failure 2: S45-S57.
    • (1996) J Cardiac Failure , vol.2
    • Fujita, S.1    Endoh, M.2
  • 16
    • 0021895138 scopus 로고
    • 2+ indicators with greatly improved fluorescence properties
    • 2+ indicators with greatly improved fluorescence properties. J Biol Chem 260: 3440-3450.
    • (1985) J Biol Chem , vol.260 , pp. 3440-3450
    • Grynkiewicz, G.1    Poenie, M.2    Tsien, R.Y.3
  • 17
    • 0029613261 scopus 로고
    • Mechanisms of action of calcium-sensitizing drugs
    • HAIKALA H, LINDÉN IB, 1995. Mechanisms of action of calcium-sensitizing drugs. J Cardiovasc Pharmacol 26 (Suppl. 1): S10-S19.
    • (1995) J Cardiovasc Pharmacol , vol.26 , Issue.SUPPL. 1
    • Haikala, H.1    Lindén, I.B.2
  • 19
    • 0028791569 scopus 로고
    • Troponin C-mediated calcium sensitization by levosimendan accelerates the proportional development of isometric tension
    • HAIKALA H, LEVIJOKI J, LINDÉN IB, 1995b. Troponin C-mediated calcium sensitization by levosimendan accelerates the proportional development of isometric tension. J Mol Cell Cardiol 27: 2155-2165.
    • (1995) J Mol Cell Cardiol , vol.27 , pp. 2155-2165
    • Haikala, H.1    Levijoki, J.2    Lindén, I.B.3
  • 21
    • 0030955524 scopus 로고    scopus 로고
    • The role of cAMP- and cGMP-dependent protein kinases in the cardiac actions of the new calcium sensitizer, levosimendan
    • HAIKALA H, KAHEINEN P, LEVIJOKI J, LINDÉN IB, 1997. The role of cAMP- and cGMP-dependent protein kinases in the cardiac actions of the new calcium sensitizer, levosimendan. Cardiovasc Res 34: 536-546.
    • (1997) Cardiovasc Res , vol.34 , pp. 536-546
    • Haikala, H.1    Kaheinen, P.2    Levijoki, J.3    Lindén, I.B.4
  • 22
    • 0026332469 scopus 로고
    • Calcium-sensitizing inotropic agents in the treatment of heart failure: A critical view
    • HAJJAR RJ, GWATHMEY JK, 1991. Calcium-sensitizing inotropic agents in the treatment of heart failure: a critical view. Cardiovasc Drugs Ther 5: 961-966.
    • (1991) Cardiovasc Drugs Ther , vol.5 , pp. 961-966
    • Hajjar, R.J.1    Gwathmey, J.K.2
  • 25
    • 0027481108 scopus 로고
    • Effects of the positive inotropic agent Org 30029 on developed force and aequorin light transients in intact canine ventricular myocardium
    • KAWABATA Y, ENDOH M, 1993. Effects of the positive inotropic agent Org 30029 on developed force and aequorin light transients in intact canine ventricular myocardium. Circ Res 72: 597-606.
    • (1993) Circ Res , vol.72 , pp. 597-606
    • Kawabata, Y.1    Endoh, M.2
  • 26
    • 0023187650 scopus 로고
    • Effects of β-adrenoceptor stimulation on intracellular Ca transients and tension in rat ventricular muscle
    • KURIHARA S, KONISHI M, 1987. Effects of β-adrenoceptor stimulation on intracellular Ca transients and tension in rat ventricular muscle. Pflügers Arch 409: 427-437.
    • (1987) Pflügers Arch , vol.409 , pp. 427-437
    • Kurihara, S.1    Konishi, M.2
  • 27
    • 0027276723 scopus 로고
    • The two mechanisms of action of racemic cardiotonic EMD 53998, calcium sensitization and phosphodiesterase inhibition, reside in different enantiomers
    • LUES I, BEIER N, JONAS R, KLOCKOW M, HAEUSLER G, 1993. The two mechanisms of action of racemic cardiotonic EMD 53998, calcium sensitization and phosphodiesterase inhibition, reside in different enantiomers. J Cardiovasc Pharmacol 21: 883-892.
    • (1993) J Cardiovasc Pharmacol , vol.21 , pp. 883-892
    • Lues, I.1    Beier, N.2    Jonas, R.3    Klockow, M.4    Haeusler, G.5
  • 28
    • 0023925939 scopus 로고
    • In vitro investigations on a new positive inotropic and vasodilating agent (BM 14.478) that increases myocardial cyclic AMP content and myofibrillar calcium sensitivity
    • MÜLLER-BECKMANN B, FREUND P, HONERJÄGER P, KLING L, RÜEGG JC, 1988. In vitro investigations on a new positive inotropic and vasodilating agent (BM 14.478) that increases myocardial cyclic AMP content and myofibrillar calcium sensitivity. J Cardiovasc Pharmacol 11: 8-16.
    • (1988) J Cardiovasc Pharmacol , vol.11 , pp. 8-16
    • Müller-Beckmann, B.1    Freund, P.2    Honerjäger, P.3    Kling, L.4    Rüegg, J.C.5
  • 30
    • 0025193062 scopus 로고
    • 2+ transients and contractile properties by β-adrenoceptor stimulation in ferret ventricular muscles
    • 2+ transients and contractile properties by β-adrenoceptor stimulation in ferret ventricular muscles. J Physiol 423: 221-240.
    • (1990) J Physiol , vol.423 , pp. 221-240
    • Okazaki, O.1    Suda, N.2    Hongo, K.3    Konishi, M.4    Kurihara, S.5
  • 35
    • 0028148892 scopus 로고
    • Hemodynamic, neurohumoral, and myocardial energetic effects of pimobendan, a novel calcium-sensitizing compound, in patients with mild to moderate heart failure
    • REMME WJ, KRUIJSSEN DACM, VAN HOOGENHUYZE DCA, KRAUSS XH, BARTELS GL, STORM CJ, DE LEEUW PW, 1994. Hemodynamic, neurohumoral, and myocardial energetic effects of pimobendan, a novel calcium-sensitizing compound, in patients with mild to moderate heart failure. J Cardiovasc Pharmacol 24: 730-739.
    • (1994) J Cardiovasc Pharmacol , vol.24 , pp. 730-739
    • Remme, W.J.1    Kruijssen, D.A.C.M.2    Van Hoogenhuyze, D.C.A.3    Krauss, X.H.4    Bartels, G.L.5    Storm, C.J.6    De Leeuw, P.W.7
  • 36
    • 34250423092 scopus 로고
    • Positive inotropic effects of phenylephrine in the isolated rabbit papillary muscle mediated both by α-and β-adrenoceptors
    • SCHÜMANN HJ, ENDOH M, WAGNER J, 1974. Positive inotropic effects of phenylephrine in the isolated rabbit papillary muscle mediated both by α-and β-adrenoceptors. Naunyn-Schmiedeberg's Arch Pharmacol 284: 133-148.
    • (1974) Naunyn-Schmiedeberg's Arch Pharmacol , vol.284 , pp. 133-148
    • Schümann, H.J.1    Endoh, M.2    Wagner, J.3
  • 39
    • 0031031790 scopus 로고    scopus 로고
    • + exchange to the positive inotropic effect of phenylephrine, endothelin-3 and angiotensin II in rabbit ventricular myocardium
    • + exchange to the positive inotropic effect of phenylephrine, endothelin-3 and angiotensin II in rabbit ventricular myocardium. Naunyn-Schmiedeberg's Arch Pharmacol 355: 87-96.
    • (1997) Naunyn-Schmiedeberg's Arch Pharmacol , vol.355 , pp. 87-96
    • Talukder, M.A.H.1    Endoh, M.2
  • 42
    • 0029951212 scopus 로고    scopus 로고
    • 2+ sensitizer Org-30029 reverses acidosis- and BDM-induced contractile depression in canine myocardium
    • 2+ sensitizer Org-30029 reverses acidosis- and BDM-induced contractile depression in canine myocardium. Am J Physiol 271: H1829-H1839.
    • (1996) Am J Physiol , vol.271
    • Watanabe, A.1    Tomoike, H.2    Endoh, M.3
  • 45
    • 0023318184 scopus 로고
    • 2+] related to rate of force development in twitch contraction of heart
    • 2+] related to rate of force development in twitch contraction of heart. Am J Physiol 252: H760-H770.
    • (1987) Am J Physiol , vol.252
    • Yue, D.T.1


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