메뉴 건너뛰기




Volumn 45, Issue 1, 2012, Pages 69-75

Gene expression studies in autism: Moving from the genome to the transcriptome and beyond

Author keywords

Autism; Microarray; Transcriptome

Indexed keywords

TRANSCRIPTOME;

EID: 81555207759     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2011.07.017     Document Type: Review
Times cited : (56)

References (58)
  • 1
    • 42349095075 scopus 로고    scopus 로고
    • Advances in autism genetics: on the threshold of a new neurobiology
    • Abrahams B.S., Geschwind D.H. Advances in autism genetics: on the threshold of a new neurobiology. Nat. Rev. Genet. 2008, 9:341-355.
    • (2008) Nat. Rev. Genet. , vol.9 , pp. 341-355
    • Abrahams, B.S.1    Geschwind, D.H.2
  • 4
    • 0032830639 scopus 로고    scopus 로고
    • Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2
    • Amir R.E., Van den Veyver I.B., Wan M., Tran C.Q., Francke U., Zoghbi H.Y. Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2. Nat. Genet. 1999, 23:185-188.
    • (1999) Nat. Genet. , vol.23 , pp. 185-188
    • Amir, R.E.1    Van den Veyver, I.B.2    Wan, M.3    Tran, C.Q.4    Francke, U.5    Zoghbi, H.Y.6
  • 7
    • 33644759438 scopus 로고    scopus 로고
    • Genomic and functional profiling of duplicated chromosome 15 cell lines reveal regulatory alterations in UBE3A-associated ubiquitin-proteasome pathway processes
    • Baron C.A., Tepper C.G., Liu S.Y., Davis R.R., Wang N.J., Schanen N.C., Gregg J.P. Genomic and functional profiling of duplicated chromosome 15 cell lines reveal regulatory alterations in UBE3A-associated ubiquitin-proteasome pathway processes. Hum. Mol. Genet. 2006, 15:853-869.
    • (2006) Hum. Mol. Genet. , vol.15 , pp. 853-869
    • Baron, C.A.1    Tepper, C.G.2    Liu, S.Y.3    Davis, R.R.4    Wang, N.J.5    Schanen, N.C.6    Gregg, J.P.7
  • 8
    • 70349794451 scopus 로고    scopus 로고
    • Immune proteins in brain development and synaptic plasticity
    • Boulanger L.M. Immune proteins in brain development and synaptic plasticity. Neuron 2009, 64:93-109.
    • (2009) Neuron , vol.64 , pp. 93-109
    • Boulanger, L.M.1
  • 9
    • 63549113237 scopus 로고    scopus 로고
    • Molecular genetics of autism
    • Cantor R.M. Molecular genetics of autism. Curr. Psychiatry Rep. 2009, 11:137-142.
    • (2009) Curr. Psychiatry Rep. , vol.11 , pp. 137-142
    • Cantor, R.M.1
  • 10
    • 77953936121 scopus 로고    scopus 로고
    • An integrative multi-dimensional genetic and epigenetic strategy to identify aberrant genes and pathways in cancer
    • Chari R., Coe B.P., Vucic E.A., Lockwood W.W., Lam W.L. An integrative multi-dimensional genetic and epigenetic strategy to identify aberrant genes and pathways in cancer. BMC Syst. Biol. 2010, 4:67.
    • (2010) BMC Syst. Biol. , vol.4 , pp. 67
    • Chari, R.1    Coe, B.P.2    Vucic, E.A.3    Lockwood, W.W.4    Lam, W.L.5
  • 11
    • 54049144653 scopus 로고    scopus 로고
    • Copy-number variations associated with neuropsychiatric conditions
    • Cook E.H., Scherer S.W. Copy-number variations associated with neuropsychiatric conditions. Nature 2008, 455:919-923.
    • (2008) Nature , vol.455 , pp. 919-923
    • Cook, E.H.1    Scherer, S.W.2
  • 15
    • 75049083298 scopus 로고    scopus 로고
    • Genome-scale approaches to the epigenetics of common human disease
    • Feinberg A.P. Genome-scale approaches to the epigenetics of common human disease. Virchows Arch. 2010, 456:13-21.
    • (2010) Virchows Arch. , vol.456 , pp. 13-21
    • Feinberg, A.P.1
  • 16
    • 67049118065 scopus 로고    scopus 로고
    • Epidemiology of pervasive developmental disorders
    • Fombonne E. Epidemiology of pervasive developmental disorders. Pediatr. Res. 2009, 65:591-598.
    • (2009) Pediatr. Res. , vol.65 , pp. 591-598
    • Fombonne, E.1
  • 17
    • 33845797961 scopus 로고    scopus 로고
    • The genetics of autistic disorders and its clinical relevance: a review of the literature
    • Freitag C.M. The genetics of autistic disorders and its clinical relevance: a review of the literature. Mol. Psychiatry 2007, 12:2-22.
    • (2007) Mol. Psychiatry , vol.12 , pp. 2-22
    • Freitag, C.M.1
  • 18
    • 34447527654 scopus 로고    scopus 로고
    • Neuroscience. Autism's cause may reside in abnormalities at the synapse
    • Garber K. Neuroscience. Autism's cause may reside in abnormalities at the synapse. Science 2007, 317:190-191.
    • (2007) Science , vol.317 , pp. 190-191
    • Garber, K.1
  • 20
    • 67650732715 scopus 로고    scopus 로고
    • Advances in autism
    • Geschwind D.H. Advances in autism. Annu. Rev. Med. 2009, 60:367-380.
    • (2009) Annu. Rev. Med. , vol.60 , pp. 367-380
    • Geschwind, D.H.1
  • 25
    • 62149112931 scopus 로고    scopus 로고
    • Chromosome 15q11-13 duplication syndrome brain reveals epigenetic alterations in gene expression not predicted from copy number
    • Hogart A., Leung K.N., Wang N.J., Wu D.J., Driscoll J., Vallero R.O., Schanen N.C., LaSalle J.M. Chromosome 15q11-13 duplication syndrome brain reveals epigenetic alterations in gene expression not predicted from copy number. J. Med. Genet. 2009, 46:86-93.
    • (2009) J. Med. Genet. , vol.46 , pp. 86-93
    • Hogart, A.1    Leung, K.N.2    Wang, N.J.3    Wu, D.J.4    Driscoll, J.5    Vallero, R.O.6    Schanen, N.C.7    LaSalle, J.M.8
  • 26
    • 33746858084 scopus 로고    scopus 로고
    • Gene expression profiling of lymphoblastoid cell lines from monozygotic twins discordant in severity of autism reveals differential regulation of neurologically relevant genes
    • Hu V.W., Frank B.C., Heine S., Lee N.H., Quackenbush J. Gene expression profiling of lymphoblastoid cell lines from monozygotic twins discordant in severity of autism reveals differential regulation of neurologically relevant genes. BMC Genomics 2006, 7:118.
    • (2006) BMC Genomics , vol.7 , pp. 118
    • Hu, V.W.1    Frank, B.C.2    Heine, S.3    Lee, N.H.4    Quackenbush, J.5
  • 27
    • 66349087284 scopus 로고    scopus 로고
    • Gene expression profiling of lymphoblasts from autistic and nonaffected sib pairs: altered pathways in neuronal development and steroid biosynthesis
    • Hu V.W., Nguyen A., Kim K.S., Steinberg M.E., Sarachana T., Scully M.A., Soldin S.J., Luu T., Lee N.H. Gene expression profiling of lymphoblasts from autistic and nonaffected sib pairs: altered pathways in neuronal development and steroid biosynthesis. PLoS One 2009, 4:e5775.
    • (2009) PLoS One , vol.4
    • Hu, V.W.1    Nguyen, A.2    Kim, K.S.3    Steinberg, M.E.4    Sarachana, T.5    Scully, M.A.6    Soldin, S.J.7    Luu, T.8    Lee, N.H.9
  • 28
    • 66349137661 scopus 로고    scopus 로고
    • Gene expression profiling differentiates autism case-controls and phenotypic variants of autism spectrum disorders: evidence for circadian rhythm dysfunction in severe autism
    • Hu V.W., Sarachana T., Kim K.S., Nguyen A., Kulkarni S., Steinberg M.E., Luu T., Lai Y., Lee N.H. Gene expression profiling differentiates autism case-controls and phenotypic variants of autism spectrum disorders: evidence for circadian rhythm dysfunction in severe autism. Autism Res. 2009, 2:78-97.
    • (2009) Autism Res. , vol.2 , pp. 78-97
    • Hu, V.W.1    Sarachana, T.2    Kim, K.S.3    Nguyen, A.4    Kulkarni, S.5    Steinberg, M.E.6    Luu, T.7    Lai, Y.8    Lee, N.H.9
  • 30
    • 0000984981 scopus 로고
    • The original description of autism, with excellent case examples
    • Kanner L. The original description of autism, with excellent case examples. Nerv. Child 1943, 2:217-250.
    • (1943) Nerv. Child , vol.2 , pp. 217-250
    • Kanner, L.1
  • 32
    • 79953716318 scopus 로고    scopus 로고
    • Genome-wide expression studies in Autism spectrum disorder, Rett syndrome, and Down syndrome
    • 2010 Dec 2. [Epub ahead of print]
    • Lintas C., Sacco R., Persico A.M. Genome-wide expression studies in Autism spectrum disorder, Rett syndrome, and Down syndrome. Neurobiol. Dis. 2010, 2010 Dec 2. [Epub ahead of print].
    • (2010) Neurobiol. Dis.
    • Lintas, C.1    Sacco, R.2    Persico, A.M.3
  • 43
    • 0035856428 scopus 로고    scopus 로고
    • Postmortem brain abnormalities of the glutamate neurotransmitter system in autism
    • Purcell A.E., Jeon O.H., Zimmerman A.W., Blue M.E., Pevsner J. Postmortem brain abnormalities of the glutamate neurotransmitter system in autism. Neurology 2001, 57:1618-1628.
    • (2001) Neurology , vol.57 , pp. 1618-1628
    • Purcell, A.E.1    Jeon, O.H.2    Zimmerman, A.W.3    Blue, M.E.4    Pevsner, J.5
  • 48
    • 77957912870 scopus 로고    scopus 로고
    • The genetics of child psychiatric disorders: focus on autism and Tourette syndrome
    • State M.W. The genetics of child psychiatric disorders: focus on autism and Tourette syndrome. Neuron 2010, 68:254-269.
    • (2010) Neuron , vol.68 , pp. 254-269
    • State, M.W.1
  • 51
  • 54
    • 57749195712 scopus 로고    scopus 로고
    • RNA-Seq: a revolutionary tool for transcriptomics
    • Wang Z., Gerstein M., Snyder M. RNA-Seq: a revolutionary tool for transcriptomics. Nat. Rev. Genet. 2009, 10:57-63.
    • (2009) Nat. Rev. Genet. , vol.10 , pp. 57-63
    • Wang, Z.1    Gerstein, M.2    Snyder, M.3
  • 56
    • 70349956425 scopus 로고    scopus 로고
    • A genome-wide linkage and association scan reveals novel loci for autism
    • Weiss L.A., Arking D.E., Daly M.J., Chakravarti A. A genome-wide linkage and association scan reveals novel loci for autism. Nature 2009, 461:802-808.
    • (2009) Nature , vol.461 , pp. 802-808
    • Weiss, L.A.1    Arking, D.E.2    Daly, M.J.3    Chakravarti, A.4
  • 57
    • 6344271762 scopus 로고    scopus 로고
    • Autism and tuberous sclerosis
    • Wiznitzer M. Autism and tuberous sclerosis. J. Child Neurol. 2004, 19:675-679.
    • (2004) J. Child Neurol. , vol.19 , pp. 675-679
    • Wiznitzer, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.