Three-dimensional high frequency power Doppler ultrasonography for the assessment of microvasculature during fracture healing in a rat model

Journal of Orthopaedic Research

Volumn 30, Issue 1, 2012, Pages 137-143

  Sun, Ming Hui ^a   Leung, Kwok Sui ^a,b   Zheng, Yong Ping ^c   Huang, Yan Ping ^c   Wang, Li Ke ^c   Qin, Ling ^a,b   Leung, Andraay Hon Chi ^a   Chow, Simon Kwoon Ho ^a   Cheung, Wing Hoi ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY   (China)

^c HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

Author keywords

3D power Doppler; fracture healing; high frequency ultrasound; microCT microangiography; microvasculature

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD FLOW; CALLUS; DOPPLER ECHOGRAPHY; FEMALE; FEMUR FRACTURE; FRACTURE HEALING; MICROANGIOGRAPHY; MICROVASCULATURE; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; OSTEOPOROSIS; PRIORITY JOURNAL; RAT; THREE DIMENSIONAL HIGH FREQUENCY POWER DOPPLER ULTRASONOGRAPHY; VASCULARIZATION;

ANGIOGRAPHY; ANIMALS; DISEASE MODELS, ANIMAL; FEMALE; FEMORAL FRACTURES; FEMUR; FRACTURE HEALING; IMAGING, THREE-DIMENSIONAL; MICROCIRCULATION; OSTEOPOROSIS; OVARIECTOMY; RATS; RATS, SPRAGUE-DAWLEY; ULTRASONOGRAPHY, DOPPLER; X-RAY MICROTOMOGRAPHY;

EID: 81555195242     PISSN: 07360266     EISSN: 1554527X     Source Type: Journal    
DOI: 10.1002/jor.21490     Document Type: Article

References (34)

1. Augat P, Simon U, Liedert A, et al. 2005. Mechanics and mechano-biology of fracture healing in normal and osteoporotic bone. Osteoporos Int 16: S36-S43. (Pubitemid 46232119)
2. Gruber R, Koch H, Doll BA, et al. 2006. Fracture healing in the elderly patient. Exp Gerontol 41: 1080-1093. (Pubitemid 44820727)
3. Bonnarens F, Einhorn TA,. 1984. Production of a standard closed fracture in laboratory animal bone. J Orthop Res 2: 97-101. (Pubitemid 14034681)
4. Leung KS, Shi HF, Cheung WH, et al. 2009. Low-magnitude high-frequency vibration accelerates callus formation, mineralization, and fracture healing in rats. J Orthop Res 27: 458-465.
5. Shi HF, Cheung WH, Qin L, et al. 2010. Low-magnitude high-frequency vibration treatment augments fracture healing in ovariectomy-induced osteoporotic bone. Bone 46: 1299-1305.
6. Qin L, Zhang G, Sheng H, et al. 2006. Multiple bioimaging modalities in evaluation of an experimental osteonecrosis induced by a combination of lippolysaccharide and methylprednisolone. Bone 39: 863-871. (Pubitemid 44311715)
7. Zhang G, Qin L, Cheung WH, et al. 2007. Epimedium-derived phytoestrogen exert beneficial effect on preventing steroid-associated osteonecrosis in rabbits with inhibition of both thrombosis and lipid-deposition. Bone 40: 685-692. (Pubitemid 46187235)
8. Zhou XZ, Zhang G, Dong QR, et al. 2009. Low dose X-irradiation promotes mineralization of fracture callus in a rat model. Arch Orthop Trauma Surg 129: 125-132.
9. Rubin JM, Bude RO, Carson PL, et al. 1994. Power Doppler US: a potentially useful alternative to mean frequency-based color Doppler US. Radiology 190: 853-856.
10. Bude RO, Rubin JM,. 1996. Power Doppler sonography. Radiology 200: 21-23.
11. Caruso G, Lagalla R, Derchi L, et al. 2000. Monitoring of fracture calluses with color Doppler sonography. J Clin Ultrasound 28: 20-27. (Pubitemid 30027383)
12. Rawool NM, Goldberg BB, Forsberg F, et al. 2003. Power Doppler assessment of vascular changes during fracture treatment with low-intensity ultrasound. J Ultrasound Med 22: 145-153. (Pubitemid 36143088)
13. Risselada M, Kramer M, Saunders JH, et al. 2006. Power Doppler assessment of the neovascularization during uncomplicated fracture healing of long bones in dogs and cats. Vet Radiol Ultrasound 47: 301-306.
14. Downey DB, Fenster A,. 1995. Vascular imaging with a three dimensional power Doppler system. Am J Roentgenol 165: 665-668.
15. Carson Pl, Fowlkes JB,. 1998. 3D power Doppler image quantification of breast masses. Ultrasound Med Biol 24: 945-952. (Pubitemid 28460027)
16. Fortunato SJ,. 1996. The use of power Doppler angiography of the fetal brain. Ultrasound Obstet Gynecol 8: 417-421.
17. Pairleitner H, Steiner H, Hasenoehrl G, et al. 1999. Three-dimensional power Doppler sonography: imaging and quantifying blood flow and vascularization. Ultrasound Obstet Gynecol 14: 139-143. (Pubitemid 29440656)
18. Trop-Pedersen ST, Terslev L,. 2008. Settings and artefacts relevant in colour/power Doppler ultrasound in rheumatology. Ann Rheum Dis 67: 143-149. (Pubitemid 351183300)
19. Qin L, Leung KS, Leung P,. 2005. Phytoestrogen-rich herb formula "XLGB" prevents OVX-induced deterioration of musculoskeletal tissues at the hip in old rats. J Bone Miner Metab 23 (Suppl): 55-61.
20. Zhang G, Qin L, Leung PC, et al. 2006. Flavonoids derived from herbal Epimedium Brevicornum Maxim prevent OVX-induced osteoporosis in rats independent of its enhancement in intestinal calcium absorption. Bone 38: 818-825. (Pubitemid 44498593)
21. Shymkiw RC, Zernicke RF,. 2001. Evaluation of laser-Doppler perfusion imaging for measurement of blood flow in cortical bone. J Appl Physiol 90: 1314-1318. (Pubitemid 32220914)
22. Raines AL, Sunwoo MH, Thacker K, et al. 2010. Angiogenesis in hyaluronan treated bone repair. The 56th Annual Meeting of the Orthopaedic Research Society: paper no. 265.
23. Zeng ZH, Yu L, Xiao X,. 2005. Effect of VEGF on angiogenesis during bone fracture repair. Chin J Exp Surg 22: 727-728.
24. Kollmann C, Turetschek K, Mostbeck G,. 1998. Amplitude-coded colour Doppler sonography: physical principles and technique. Eur Radiol 8: 649-656. (Pubitemid 128546291)
25. Zheng LW, Ma L, Cheung LK,. 2008. Changes in blood perfusion and bone healing induced by nicotine during distraction osteogenesis. Bone 43: 355-361.
26. Pairleitner H,. 1999. Three-dimensional color histogram using three-dimensional power Doppler. In:, Kurjak A, editor. Three dimensional power Doppler in obstetrics and gynecology, 1st ed. London: The Parthenon Publishing Group Limited; p 35-38.
27. Lu C, Marcucio R, Miclau T,. 2006. Assessing angiogenesis during fracture healing. Iowa Orthop J 26: 17-26.
28. Risselada M, Van Bree H, Kramer M, et al. 2006. Evaluation of nonunion fractures in dogs by use of B-mode ultrasonography, power Doppler ultrasonography, radiography, and histologic examination. Am J Vet Res 67: 1354-1361. (Pubitemid 44275490)
29. Goertz DE, Christopher DA, Yu JL,. 2000. High-frequency color flow imaging of the microcirculation. Ultrasound Med Biol 26: 63-71. (Pubitemid 30045524)
30. Goertz DE, Yu JL, Kerbel RS, et al. 2003. High-frequency 3-D color-flow imaging of the microcirculation. Ultrasound Med Biol 29: 39-51. (Pubitemid 36207637)
31. Martinoli C, Derchi LE,. 1997. Gain setting in power Doppler. Radiology 202: 284-285.
32. Bude RO, Rubin JM, Adler RS,. 1994. Power versus conventional color Doppler sonography: comparison in the depiction of normal intrarenal vasculature. Radiology 192: 777-780. (Pubitemid 24266796)
33. Fleischer AC,. 2000. Sonographic depiction of tumor vascularity and flow: from in vivo models to clinical applications. J Ultrasound Med 19: 55-61. (Pubitemid 30027164)
34. Delorme S, Peschke P, Zuna I, et al. 2001. Imaging the smallest tumor vessels using color Doppler ultrasound in an experiment. Radiology 41: 168-172. (Pubitemid 32172283)