Esophageal tissue engineering: An in-depth review on scaffold design

Biotechnology and Bioengineering

Volumn 109, Issue 1, 2012, Pages 1-15

  Tan, J Y ^a   Chua, C K ^a   Leong, K F ^a   Chian, K S ^a   Leong, W S ^a   Tan, L P ^b  

^a NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

^b NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

Author keywords

Esophagus; Scaffold; Scaffold design; Scaffold fabrication; Tissue engineering

Indexed keywords

DECELLULARIZED; ENGINEERING PROCESS; ESOPHAGEAL CANCER; ESOPHAGEAL TISSUE ENGINEERING; ESOPHAGEAL TISSUES; ESOPHAGUS; FUNCTIONAL RECOVERY; KEY ELEMENTS; MATRIX; SCAFFOLD FABRICATION; SURGICAL PROCEDURES; TISSUE DEVELOPMENT; TISSUE QUALITY;

DESIGN; SCAFFOLDS; TISSUE; TISSUE ENGINEERING;

SCAFFOLDS (BIOLOGY);

ANGIOPOIETIN 1; COLLAGEN SPONGE; FIBROBLAST GROWTH FACTOR 2; MOLECULAR SCAFFOLD; POLYCAPROLACTONE; POLYLACTIDE; SILICON; TRANSFORMING GROWTH FACTOR BETA; VASCULOTROPIN;

ANATOMY; ANGIOGENESIS; BIOCOMPATIBILITY; BIOENGINEERING; BIOMECHANICS; CELL ADHESION; CELL MEMBRANE PERMEABILITY; CELL MIGRATION; DYSPHAGIA; ESOPHAGEAL TISSUE ENGINEERING; ESOPHAGUS CANCER; ESOPHAGUS FUNCTION; ESOPHAGUS MUCOSA; ESOPHAGUS MUSCLE; ESOPHAGUS RECONSTRUCTION; HUMAN; MICROTECHNOLOGY; MUSCLE INNERVATION; MUSCULARIS PROPRIA; NANOFABRICATION; NERVE FIBER DEGENERATION; NONHUMAN; REVIEW; SCHWANN CELL; SUBMUCOSA; TISSUE ENGINEERING; VASCULARIZATION;

ESOPHAGUS; HUMANS; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 81455131518     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.23323     Document Type: Review

References (153)

1. Badylak SF. 2002. The extracellular matrix as a scaffold for tissue reconstruction. Semin Cell Dev Biol 13(5): 377-383.
2. Badylak SF, Meurling S, Chen M, Spievack A, Simmons-Byrd A. 2000. Resorbable bioscaffold for esophageal repair in a dog model. J Pediatr Surg 35(7): 1097-1103.
3. Badylak SF, Vorp DA, Spievack AR, Simmons-Byrd A, Hanke J, Freytes DO, Thapa A, Gilbert TW, Nieponice A. 2005a. Esophageal reconstruction with ECM and muscle tissue in a dog model. J Surg Res 128(1): 87-97.
4. Badylak SF, Vorp DA, Spievack AR, Simmons-Byrd A, Hanke J, Freytes DO, Thapa A, Gilbert TW, Nieponice A. 2005b. Esophageal reconstruction with ECM and muscle tissue in a dog model. J Surg Res 128(1): 87-97.
5. Badylak SF, Nieponice A, Gilbert TW. 2006. Reinforcement of esophageal anastomoses with an extracellular matrix scaffold in a canine model. Ann Thorac Surg 82(6): 2050-2058.
6. Badylak SF, Agrawal V, Brown BN, Beattie AJ, Gilbert TW. 2009a. Evidence of innervation following extracellular matrix scaffold-mediated remodelling of muscular tissues. J Tissue Eng Regen Med 3(8): 590-600.
7. Badylak SF, Nieponice A, McGrath K, Qureshi I, Beckman EJ, Luketich JD, Gilbert TW. 2009b. An extracellular matrix scaffold for esophageal stricture prevention after circumferential EMR. Gastrointest Endosc 69(2): 289-296.
8. Bashur CA, Shaffer RD, Dahlgren LA, Guelcher SA, Goldstein AS. 2009. Effect of fiber diameter and alignment of electrospun polyurethane meshes on mesenchymal progenitor cells. Tissue Eng 15(9): 2435-2445.
9. Beckstead BL, Pan S, Bhrany AD, Bratt-Leal AM, Ratner BD, Giachelli CM. 2005. Esophageal epithelial cell interaction with synthetic and natural scaffolds for tissue engineering. Biomaterials 26(31): 6217-6228.
10. Bedirli A, Ferahkose Z, Kerem M, Azili C, Sozuer EM, Akin M. 2008. Comparison of free jejunal graft with gastric pull-up reconstruction after resection of hypopharyngeal and cervical esophageal carcinoma. Dis Esophagus 21(4): 340-345.
11. Belkas JS, Shoichet MS, Midha R. 2004. Axonal guidance channels in peripheral nerve regeneration. Oper Tech Orthop 14(3): 190-198.
12. Bezuidenhout D, Davies N, Zilla P. 2002. Effect of well defined dodecahedral porosity on inflammation and angiogenesis. ASAIO J 48(5): 465-471.
13. Bhrany AD, Beckstead BL, Lang TC, Farwell DG, Giachelli CM, Ratner BD. 2006. Development of an esophagus acellular matrix tissue scaffold. Tissue Eng 12(2): 319-330.
14. Billiar K, Murray J, Laude D, Abraham G, Bachrach N. 2001. Effects of carbodiimide crosslinking conditions on the physical properties of laminated intestinal submucosa. J Biomed Mater Res A 56(1): 101-108.
15. Bonavina L, Venturi M, Colombo L, Segalin A, Mussini E, Peracchia A. 1995. Elastic properties of the normal human esophagus-A biochemical-study. Gastroenterology 108(4): A573-A573.
16. Bonavina L, Via A, Incarbone R, Saino G, Peracchia A. 2003. Results of surgical therapy in patients with Barrett's adenocarcinoma. World J Surg 27(9): 1062-1066.
17. Bose S, Darsell J, Kintner M, Hosick H, Bandyopadhyay A. 2003. Pore size and pore volume effects on alumina and TCP ceramic scaffolds. Mater Sci Eng C 23: 479-486.
18. Boyan BD, Hummert TW, Dean DD, Schwartz Z. 1996. Role of material surfaces in regulating bone and cartilage cell response. Biomaterials 17(2): 137-146.
19. Bozkurt A, Brook GA, Moellers S, Lassner F, Sellhaus B, Weis J, Woeltje M, Pallua N. 2007. In vitro assessment of axonal growth using dorsal root ganglia explants in a novel three-dimensional collagen matrix. Tissue Eng 13(12): 2971-2979.
20. Brasseur JG, Nicosia MA, Pal A, Miller LS. 2007. Function of longitudinal vs circular muscle fibers in esophageal peristalsis, deduced with mathematical modeling. World J Gastroenterol 13(9): 1335-1346.
21. Briel JW, Tamhankar AP, Hagen JA, DeMeester SR, Johansson J, Choustoulakis E, Peters JH, Bremner CG, DeMeester TR. 2004. Prevalence and risk factors for ischemia, leak, and stricture of esophageal anastomosis: Gastric pull-up versus colon interposition. J Am Coll Surg 198(4): 536-541.
22. Bury JP, Green N, Huang QZ, Khan L, Battaglia G, Corfe B, MacNeil S. 2010. The development and characterization of an organotypic tissue-engineered human esophageal mucosal model. Tissue Eng A 16(3): 1053-1064.
23. Carmeliet P. 2000. Mechanisms of angiogenesis and arteriogenesis. Nat Med 6(4): 389-395.
24. Cha JM, Park SN, Noh SH, Suh H. 2006. Time-dependent modulation of alignment and differentiation of smooth muscle cells seeded on a porous substrate undergoing cyclic mechanical strain. Artif Organs 30(4): 250-258.
25. Chang SY, Chu PY. 2009. Reconstruction of the hypopharynx after surgical treatment of squamous cell carcinoma. J Chin Med Assoc 72(7): 351-355.
26. Chen Y, Shamu T, Chen H, Besmer P, Sawyers CL, Chi P. 2011. Visualization of the interstitial cells of Cajal (ICC) network in mice. J Vis Exp (53): e2802.
27. Chew SY, Cao HQ, Liu T. 2009. The application of nanofibrous scaffolds in neural tissue engineering. Adv Drug Deliv Rev 61(12): 1055-1064.
28. Chong CK, Chan WY. 2009. Perfusion bioreactors improve oxygen transport and cell distribution in esophageal smooth muscle construct. 13th International Conference on Biomedical Engineering 23(1-3):1523-1526.
29. Clark JM, Glagov S. 1985. Transmural organization of the arterial media-The lamellar unit revisited. Arteriosclerosis 5(1): 19-34.
30. Cleary E. 1992. Skin. In: Comper W, editor. Extracellular matrix. Amsterdam: Harwood Academic Publishers.
31. Corey JM, Lin DY, Mycek KB, Chen Q, Samuel S, Feldman EL, Martin DC. 2007. Aligned electrospun nanofibers specify the direction of dorsal root ganglia neurite growth. J Biomed Mater Res A 83A(3): 636-645.
32. Davis PA, Law S, Wong J. 2003. Colonic interposition after esophagectomy for cancer. Arch Surg 138(3): 303-308.
33. Deng YM, Tuch BE, D RW. 2000. Transmission of porcine endogenous retroviruses in severe combined immunodeficient mice xenotransplanted with fetal porcine pancreatic cells. Transplantation 70(7): 1010-1016.
34. Discher DE, Griffin MA, Sen S, Sweeney HL. 2004. Adhesion-contractile balance in myocyte differentiation. J Cell Sci 117(24): 5855-5863.
35. Doede T, Bondartschuk M, Joerck C, Schulze E, Goernig M. 2009. Unsuccessful alloplastic esophageal replacement with porcine small intestinal submucosa. Artif Organs 33(4): 328-333.
36. Egorov VI, Schastlivtsev IV, Prut EV, Baranov AO, Turusov RA. 2002. Mechanical properties of the human gastrointestinal tract. J Biomech 35(10): 1417-1425.
37. Ellis J, Chaudhuri JB. 2007. Poly(lactic-co-glycolic acid) hollow fibre membranes for use as a tissue engineering scaffold. Biotechnol Bioeng 96(1): 177-187.
38. Fan Y, Gregersen H, Kassab GS. 2004. A two-layered mechanical model of the rat esophagus. Experiment and theory. Biomed Eng Online 3(1): 40.
39. Freed LE, Vunjaknovakovic G, Biron RJ, Eagles DB, Lesnoy DC, Barlow SK, Langer R. 1994. Biodegradable polymer scaffolds for tissue engineering. Biotechnology (NY) 12(7): 689-693.
40. Freud E, Efrati I, Kidron D, Finally R, Mares AJ. 1999. Comparative experimental study of esophageal wall regeneration after prosthetic replacement. J Biomed Mater Res A 45(2): 84-91.
41. Fuchs JR, Nasseri BA, Vacanti JP. 2001. Tissue engineering: A 21st century solution to surgical reconstruction. Ann Thorac Surg 72(2): 577-591.
42. Fung YC. 1993. Biomechanics: Mechanical properties of living tissues. New York: Springer-Verlag. xviii, 568 p.
43. Goldstein AS, Lee JY, Bashur CA, Schmidt CE. 2009. Polypyrrole-coated electrospun PLGA nanofibers for neural tissue applications. Biomaterials 30(26): 4325-4335.
44. Gonzalez SLA, Monreal FA, Fernandez SP, Cruz JMS. 2003. Experimental study using PTFE (Goretex) patches for replacement of the oesophageal wall. Eur Surg Res 35(4): 372-376.
45. Gregersen H. 2003. Biomechanics of the gastrointestinal tract: New perspectives in motility research and diagnostics. London, New York: Springer. xv, 268 p.
46. Grikscheit TC, Ochoa ER, Srinivasan A, Gaissert H, Vacanti JP. 2003. Tissue-engineered esophagus: Experimental substitution by onlay patch or interposition. J Thorac Cardiovasc Surg 126(2): 537-544.
47. Gu XS, Ding F, Yang YM, Liu J. 2011. Construction of tissue engineered nerve grafts and their application in peripheral nerve regeneration. Prog Neurobiol 93(2): 204-230.
48. Hirschi KK, Skalak TC, Peirce SM, Little CD. 2002. Vascular assembly in natural and engineered tissues. Ann NY Acad Sci 961: 223-242.
49. Hori Y, Nakamura T, Kimura D, Kaino K, Kurokawa Y, Satomi S, Shimizu Y. 2003. Effect of basic fibroblast growth factor on vascularization in esophagus tissue engineering. Int J Artif Organs 26(3): 241-244.
50. Hsu SH, Chen CY, Lu PS, Lai CS, Chen CJ. 2005. Oriented Schwann cell growth on microgrooved surfaces. Biotechnol Bioeng 92(5): 579-588.
51. Hunyady B, Mezey E, Palkovits M. 2000. Gastrointestinal immunology: Cell types in the lamina propria-A morphological review. Acta Physiol Hung 87(4): 305-328.
52. Ike O, Shimizu Y, Okada T, Natsume T, Watanabe S, Ikada Y, Hitomi S. 1989. Experimental studies on an artificial esophagus for the purpose of neoesophageal epithelization using a collagen-coated silicone tube. ASAIO Trans 35(3): 226-228.
53. Isch JA, Engum SA, Ruble CA, Davis MM, Grosfeld JL. 2001. Patch esophagoplasty using AlloDerm as a tissue scaffold. J Pediatr Surg 36(2): 266-268.
54. Jain RK, Au P, Tam J, Duda DG, Fukumura D. 2005. Engineering vascularized tissue. Nat Biotechnol 23: 821-823.
55. Janmey PA, Georges PC, Miller WJ, Meaney DF, Sawyer ES. 2006. Matrices with compliance comparable to that of brain tissue select neuronal over glial growth in mixed cortical cultures. Biophys J 90(8): 3012-3018.
56. Jansen PL, Klinge U, Anurov M, Titkova S, Jansen M, Mertens PR. 2004. Surgical mesh as a scaffold for tissue regeneration in the esophagus. Eur Surg Res 36(2): 104-111.
57. Kajitani M, Wadia Y, Hinds MT, Teach J, Swartz KR, Gregory KW. 2001. Successful repair of esophageal injury using an elastin based biomaterial patch. ASAIO J 47(4): 342-345.
58. Kerr JB. 1999. Atlas of functional histology. London: Mosby. 402 p.
59. Kim K, Yu M, Zong X, Chiu J, Fang D, Seo YS, Hsiao BS, Chu B, Hadjiargyrou M. 2003. Control of degradation rate and hydrophilicity in electrospun non-woven poly(D, L-lactide) nanofiber scaffolds for biomedical applications. Biomaterials 24(27): 4977-4985.
60. Kneser U, Schaefer DJ, Polykandriotis E, Horch RE. 2006. Tissue engineering of bone: The reconstructive surgeon's point of view. J Cell Mol Med 10(1): 7-19.
61. Kohn D, Sarmadi M, Helman J, Krebsbach P. 2002. Effects of PH on human bone marrow stromal cells in vitro: Implications for tissue engineering of bone. J Biomed Mater Res A 60: 292-299.
62. Langer R, Vacanti JP. 1993. Tissue engineering. Science 260: 920-926.
63. Leong KW, Chew SY, Mi R, Hoke A. 2008. The effect of the alignment of electrospun fibrous scaffolds on Schwann cell maturation. Biomaterials 29(6): 653-661.
64. Leong MF, Chian KS, Mhaisalkar PS, Ong WF, Ratner BD. 2009a. Effect of electrospun poly(DL-lactide) fibrous scaffold with nanoporous surface on attachment of porcine esophageal epithelial cells and protein adsorption. J Biomed Mater Res A 89(4): 1040-1048.
65. Leong MF, Rasheed MZ, Lim TC, Chian KS. 2009b. In vitro cell infiltration and in vivo cell infiltration and vascularization in a fibrous, highly porous poly(D, L-lactide) scaffold fabricated by cryogenic electrospinning technique. J Biomed Mater Res A 91(1): 231-240.
66. Levenberg S, Rouwkema J, Macdonald M, Garfein ES, Kohane DS, Darland DC, Marini R, van Blitterswijk CA, Mulligan RC, D'Amore PA, Langer R. 2005. Engineering vascularized skeletal muscle tissue. Nat Biotechnol 23(7): 879-884.
67. Leyh RG, Wilhelmi M, Walles T, Kallenbach K, Rebe P, Oberbeck A, Herden T, Haverich A, Mertsching H. 2003. Acellularized porcine heart valve scaffolds for heart valve tissue engineering and the risk of cross-species transmission of porcine endogenous retrovirus. J Thorac Cardiovasc Surg 126(4): 1000-1004.
68. Liao DH, Fan YH, Zeng YJ, Gregersen H. 2003. Stress distribution in the layered wall of the rat oesophagus. Med Eng Phys 25(9): 731-738.
69. Liao S, Li BJ, Ma ZW, Wei H, Chan C, Ramakrishna S. 2006. Biomimetic electrospun nanofibers for tissue regeneration. Biomed Mater 1(3): R45-R53.
70. Liao DH, Gregersen H, Fung YC. 2008. Determination of homeostatic elastic moduli in two layers of the esophagus. J Biomech Eng Trans of the ASME 130(1): 011005.
71. Lin C-C, Papadopoulos KP. 2007. Novel targeted therapies for advanced esophageal cancer. Dis Esophagus 20(5): 365-371.
72. Long JD, Orlando RC. 1999. Esophageal submucosal glands: Structure and function. Am J Gastroenterol 94(10): 2818-2824.
73. Lopes MF, Cabrita A, Ilharco J, Pessa P, Paiva-Carvalho J, Pires A, Patrício J. 2006a. Esophageal replacement in rat using porcine intestinal submucosa as a patch or a tube-shaped graft. Dis Esophagus 19(4): 254-259.
74. Lopes MF, Cabrita A, Ilharco J, Pessa P, Patricio J. 2006b. Grafts of porcine intestinal submucosa for repair of cervical and abdominal esophageal defects in the rat. J Inv Sur 19(2): 105-111.
75. Mann BK, Tsai AT, Scott-Burden T, West JL. 1999. Modification of surfaces with cell adhesion peptides alters extracellular matrix deposition. Biomaterials 20(23-24): 2281-2286.
76. Mariette C, Piessen G, Triboulet J-P. 2007. Therapeutic strategies in oesophageal carcinoma: Role of surgery and other modalities. Lancet Oncol 8(6): 545-553.
77. Marshall A, I CA, Barker T, Sage EH, Hauch KD, Ratner BD. 2004. Biomaterials with tightly controlled pore size that promote vascular in-growth. Polym Preprints 45(2): 100-101.
78. Martini F, Timmons MJ, Tallitsch RB. 2009. Human anatomy. San Francisco: Pearson Benjamin Cummings. xxxiii, 869 p.
79. Marzaro M, Conconi MT, Perin L, Giuliani S, Gamba P, De Coppi P. 2002. Autologous satellite cell seeding improves in vivo biocompatibility of homologous muscle acellular matrix implants. Int J Mol Med 10: 177-182.
80. Marzaro M, Vigolo S, Oselladore B, Conconi MT, Ribatti D, Giuliani S, Nico B, Perrino G, Nussdorfer GG, Parnigotto PP. 2006. In vitro and in vivo proposal of an artificial esophagus. J Biomed Mater Res A 77A(4): 795-801.
81. McKinley MP, O'Loughlin VD. 2008. Human anatomy. Boston: McGraw-Hill Higher Education. xxx, 874, 10, 6, 3, 20 p.
82. Miki H, Ando N, Ozawa S, Sato M, Hayashi K, Kitajima M. 1999. An artificial esophagus constructed of cultured human esophageal epithelial cells, fibroblasts, polyglycolic acid mesh, and collagen. ASAIO J 45(5): 502-508.
83. Mooney DJ, McNamara D, Hern D, Vacanti JP, Langer R. 1996. Stabilized polyglycolic acid-fibre based tubes for tissue engineering. Biomaterials 17(2): 115-124.
84. Mooney DJ, Chen RR, Silva EA, Yuen WW. 2007. Spatio-temporal VEGF and PDGF delivery patterns blood vessel formation and maturation. Pharm Res 24(2): 258-264.
85. Moore MJ, Friedman JA, Lewellyn EB, Mantila SM, Krych AJ, Ameenuddin S, Knight AM, Lu L, Currier BL, Spinner RJ, Marsh RW, Windebank AJ, Yaszemski, MJ. 2006. Multiple-channel scaffolds to promote spinal cord axon regeneration. Biomaterials 27(3): 419-429.
86. Morfit HM, Kramish D. 1962. Long-term end results in bridging esophageal defects in human beings with Teflon prostheses. Am J Surg 104(5): 756-760.
87. Moscoso I, Hermida-Prieto M, Mañez R, Lopez-Pelaez E, Centeno A, Diaz TM, Domenech N. 2005. Lack of cross-species transmission of porcine endogenous retrovirus in pig-to-baboon xenotransplantation with sustained depletion of anti-αGal antibodies. Transplantation 79(7): 777-782.
88. Nagashima A, Ando N, Sato M, Ozawa S, Kitajima M. 1997. Basic studies on the application of an artificial esophagus using cultured epidermal cells. Surg Today 27(10): 915-923.
89. Natsume T, Ike O, Okada T, Shimizu Y, Ikada Y, Tamura K. 1990. Experimental studies of a hybrid artificial esophagus combined with autologous mucosal cells. ASAIO Trans 36(3): M435-M437.
90. Natsume T, Ike O, Okada T, Takimoto N, Shimizu Y, Ikada Y. 1993. Porous collagen sponge for esophageal replacement. J Biomed Mater Res A 27(7): 867-875.
91. Nor JE, Christensen J, Mooney DJ, Polverini PJ. 1999. Vascular endothelial growth factor (VEGF)-mediated angiogenesis is associated with enhanced endothelial cell survival and induction of Bcl-2 expression. Am J Pathol 154(2): 375-384.
92. Oates M, Chen R, Duncan M, Hunt JA. 2007. The angiogenic potential of three-dimensional open porous synthetic matrix materials. Biomaterials 28(25): 3679-3686.
93. Ohki T, Yamato M, Ota M, Murakami D, Takagi R, Kondo M, Nakamura T, Okano T, Yamamoto M. 2009. Endoscopic transplantation of human oral mucosal epithelial cell sheets-world's first case of regenerative medicine applied to endoscopic treatment. Gastrointest Endosc 69(5): Ab253-Ab254.
94. Okano T, Shimizu T, Sekine H, Isoi Y, Yamato M, Kikuchi A. 2006. Long-term survival and growth of pulsatile myocardial tissue grafts engineered by the layering of cardiomyocyte sheets. Tissue Eng 12(3): 499-507.
95. Ozeki M, Narita Y, Kagami H, Ohmiya N, Itoh A, Hirooka Y, Niwa Y, Ueda M, Goto H. 2006. Evaluation of decellularized esophagus as a scaffold for cultured esophageal epithelial cells. J Biomed Mater Res A 79(4): 771-778.
96. Park H, Conklin J. 1999. Neuromuscular control of esophageal peristalsis. Curr Gastroenterol Rep 1(3): 186-197.
97. Pietak A, McGregor A, Gauthier S, Oleschuk R, Waldman SD. 2008. Are micropatterned substrates for directed cell organization an effective method to create ordered 3D tissue constructs? J Tissue Eng Regen Med 2(7): 450-453.
98. Prabhakaran MP, Ghasemi-Mobarakeh L, Morshed M, Nasr-Esfahani MH, Baharvand H, Kiani S, Al-Deyab SS, Ramakrishna S. 2011. Application of conductive polymers, scaffolds and electrical stimulation for nerve tissue engineering. J Tissue Eng Regen Med 5(4): E17-E35.
99. Ramakrishna S, Ghasemi-Mobarakeh L, Prabhakaran MP, Morshed M, Nasr-Esfahani MH. 2009. Electrical stimulation of nerve cells using conductive nanofibrous scaffolds for nerve tissue engineering. Tissue Eng A 15(11): 3605-3619.
100. Rao SSC, Mudipalli RS, Mujica VR, Patel RS, Zimmerman B. 2003. Effects of gender and age on esophageal biomechanical properties and sensation. Am J Gastroenterol 98(8): 1688-1695.
101. Ratner BD. 2007. A paradigm shift: Biomaterials that heal. Polym Int 56(10): 1183-1185.
102. Ratner BD, Madden LR, Mortisen DJ, Sussman EM, Dupras SK, Fugate JA, Cuy JL, Hauch KD, Laflamme MA, Murry CE. 2010. Proangiogenic scaffolds as functional templates for cardiac tissue engineering. Proc Natl Acad Sci USA 107(34): 15211-15216.
103. Rice TW, Bronner MP. 2011. The esophageal wall. Thorac Surg Clin 21(2): 299-305, x.
104. Ritchie AC, Wijaya S, Ong WF, Zhong SP, Chian KS. 2008. Dependence of alignment direction on magnitude of strain in esophageal smooth muscle cells. Biotechnol Bioeng 102(6): 1703-1711.
105. Rivron NC, Liu J, Rouwkema J, de Boer J, van Blitterswijk CA. 2008. Engineering vascularised tissues in vitro. Eur Cells Mater 15: 27-40.
106. Rouwkema J, Rivron NC, van Blitterswijk CA. 2008. Vascularization in tissue engineering. Trends Biotechnol 26(8): 434-441.
107. Ruoslahti E, Pierschbacher MD. 1987. New perspectives in cell adhesion: RGD and integrins. Science 238(4826): 491-497.
108. Sato M, Ando N, Ozawa S, Nagashima A, Kitajima M. 1993. A hybrid artificial esophagus using cultured human esophageal epithelial cells. ASAIO J 39(3): M554-M557.
109. Sato M, Ando N, Ozawa S, Miki H, Kitajima M. 1994. An artificial esophagus consisting of cultured human esophageal epithelial cells, polyglycolic acid mesh, and collagen. ASAIO J 40(3): M389-M392.
110. Saxena AK, Kofler K, Ainodhofer H, Hollwarth M. 2009. Esophagus tissue engineering: Hybrid approach with esophageal epithelium and unidirectional smooth muscle tissue component generation in vitro. J Gastrointest Surg 13(6): 1037-1043.
111. Saxena AK, Baumgart H, Komann C, Ainoedhofer H, Soltysiak P, Kofler K, Hollwarth ME. 2010. Esophagus tissue engineering: In situ generation of rudimentary tubular vascularized esophageal conduit using the ovine model. J Pediatr Surg 45(5): 859-864.
112. Schulze K, Ellerbroek S, Martin J. 2001. Matrix composition in opossum esophagus. Dig Dis Sci 46(5): 968-975.
113. Seery JP. 2002. Stem cells of the oesophageal epithelium. J Cell Sci 115(9): 1783-1789.
114. Sethuraman S, Subramanian A, Krishnan UM. 2009. Development of biomaterial scaffold for nerve tissue engineering: Biomaterial mediated neural regeneration. J Biomed Sci 16: 108.
115. Shin HJ, Lee CH, Cho IH, Kim Y-J, Lee Y-J, Kim IA, Park K-D, Yui N, Shin J-W. 2006. Electrospun PLGA nanofiber scaffolds for articular cartilage reconstruction: Mechanical stability, degradation and cellular responses under mechanical stimulation in vitro. J Biomater Sci Polym Ed 17(1): 103-119.
116. Shinhar D, Finaly R, Niska A, Mares AJ. 1998. The use of collagen-coated vicryl mesh for reconstruction of the canine cervical esophagus. Pediatr Surg Int 13(2): 84-87.
117. Simpson DG, Bowlin GL. 2006. Tissue-engineering scaffolds: Can we re-engineer mother nature? Expert Rev Med Devices 3(1): 9-15.
118. Smith M, Zhou MG, Whitlock G, Yang GH, Offer A, Hui G, Peto R, Huang ZJ, Chen ZM. 2008. Esophageal cancer and body mass index: Results from a prospective study of 220, 000 men in China and a meta-analysis of published studies. Int J Cancer 122(7): 1604-1610.
119. Sodian R, Lemke T, Fritsche C, Hoerstrup SP, Fu P, Potapov EV, Hausmann H, Hetzer R. 2002. Tissue-engineering bioreactors: A new combined cell-seeding and perfusion system for vascular tissue engineering. Tissue Eng 8(5): 863-870.
120. Sokolis DP, Stavropoulou EA, Dafalias YF. 2009. Biomechanical and histological characteristics of passive esophagus: Experimental investigation and comparative constitutive modeling. J Biomech 42(16): 2654-2663.
121. Suh H, Hwang Y-S, Kang Y-B, Nakai R, Tsutsumi S, Park J-C. 2000. Compliance of surface modified polyurethane tubular scaffold for artificial esophagus. Biomater Res 4(1): 8-12.
122. Sung H-J, Meredith JC, Johnson C, Galis ZS. 2004. The effect of scaffold degradation rate on three-dimensional cell growth and angiogenesis. Biomaterials 25(26): 5735-5742.
123. Takimoto Y, Nakamura T, Yamamoto Y, Kiyotani T, Teramachi M, Shimizu Y. 1998. The experimental replacement of a cervical esophageal segment with an artificial prosthesis with the use of collagen matrix and a silicone stent. J Thorac Cardiovasc Surg 116(1): 98-106.
124. Teixeira AI, Abrams GA, Bertics J, Murphy CJ, Nealey PF. 2003. Epithelial contact guidance on well-defined micro- and nanostructured substrates. J Cell Sci 116(10): 1881-1892.
125. Timpl R, Brown JC. 1994. The laminins. Matrix Biol 14: 275-281.
126. Tremblay PL, Hudon V, Berthod F, Germain L, Auger FA. 2005. Inosculation of tissue-engineered capillaries with the host's vasculature in a reconstructed skin transplanted on mice. Am J Transplant 5(5): 1002-1010.
127. Triboulet JP, Mariette C, Chevalier D, Amrouni H. 2001. Surgical management of carcinoma of the hypopharynx and cervical esophagus-Analysis of 209 cases. Arch Surg 136(10): 1164-1170.
128. Urita Y, Komuro H, Chen G, Shinya M, Kaneko S, Kaneko M, Ushida T. 2007. Regeneration of the esophagus using gastric acellular matrix: An experimental study in a rat model. Pediatr Surg Int 23(1): 21-26.
129. van Susante J, Buma P, Homminga G, van den Berg W, Veth R. 1998. Chondrocyte-seeded hydroxyapatite for repair of large articular cartilage defects. A pilot study in the goat. Biomaterials 19(24): 2367-2374.
130. Vanags I, Petersons A, Ose V, Ozolanta I, Kasyanov V, Laizans J, Vjaters E, Gardovskis J, Vanags A. 2003. Biomechanical properties of oesophagus wall under loading. J Biomech 36(9): 1387-1390.
131. Vassilis K, David K. 2005. Porosity of 3D biomaterial scaffolds and osteogenesis. Biomaterials 26(27): 5474-5491.
132. Villadsen GE, Storkholm JH, Hendel L, Hendrik V, Gregersen H. 1997. Impedance planimetric characterization of esophagus in systemic sclerosis patients with severe involvement of esophagus. Dig Dis Sci 42: 2317-2326.
133. Watt FM, Seery JP. 2000. Asymmetric stem-cell divisions define the architecture of human oesophageal epithelium. Curr Biol 10(22): 1447-1450.
134. Wei RQ, Tan B, Tan MY, Luo JC, Deng L, Chen XH, Li XQ, Zuo X, Zhi W, Yang P, Xie HQ, Yang ZM. 2009. Grafts of porcine small intestinal submucosa with cultured autologous oral mucosal epithelial cells for esophageal repair in a canine model. Exp Biol Med 234(4): 453-461.
135. Wong JY, Williams C, Tsuda Y, Isenberg BC, Yamato M, Shimizu T, Okano T. 2009. Aligned cell sheets grown on thermo-responsive substrates with microcontact printed protein patterns. Adv Mater 21(21): 2161-2164.
136. Wu PC, Posner MC. 2003. The role of surgery in the management of oesophageal cancer. Lancet Oncol 4(8): 481-488.
137. Xu CY, Inai R, Kotaki M, Ramakrishna S. 2004. Aligned biodegradable nanofibrous structure: A potential scaffold for blood vessel engineering. Biomaterials 25(5): 877-886.
138. Yamamoto Y, Nakamura T, Shimizu Y, Matsumoto K, Takimoto Y, Kiyotani T, Sekine T, Ueda H, Liu Y, Tamura N. 1999a. Intrathoracic esophageal replacement in the dog with the use of an artificial esophagus composed of a collagen sponge with a double-layered silicone tube. J Thorac Cardiovasc Surg 118(2): 276-286.
139. Yamamoto Y, Nakamura T, Shimizu Y, Takimoto Y, Matsumoto K, Kiyotani T, Yu L, Ueda H, Sekine T, Tamura N. 1999b. Experimental replacement of the thoracic esophagus with a bioabsorbable collagen sponge scaffold supported by a silicone stent in dogs. ASAIO J 45(4): 311-316.
140. Yamamoto Y, Nakamura T, Shimizu Y, Takimoto Y, Matsumoto K, Kiyotani T, Yu L, Ueda H, Sekine T, Tamura N. 1999c. Experimental replacement of the thoracic esophagus with a bioabsorbable collagen sponge scaffold supported by a silicone stent in dogs. ASAIO J 45: 311-316.
141. Yang SF, Leong KF, Du ZH, Chua CK. 2001. The design of scaffolds for use in tissue engineering. Part I. Traditional factors. Tissue Eng 7(6): 679-689.
142. Yang W, Fung TC, Chian KS, Chong CK. 2006a. Directional, regional, and layer variations of mechanical properties of esophageal tissue and its interpretation using a structure-based constitutive model. J Biomech Eng 128(3): 409-418.
143. Yang W, Fung TC, Chian KS, Chong CK. 2006b. Directional, regional, and layer variations of mechanical properties of esophageal tissue and its interpretation using a structure-based constitutive model. J Biomech Eng Trans ASME 128(3): 409-418.
144. Yildirim S, Koksal H, Celayir F, Erdem L, Oner M, Baykan A. 2004. Colonic interposition vs. gastric pull-up after total esophagectomy. J Gastrointest Surg 8: 675-678.
145. Yildirim E, Ayan H, Vasilets V, Fridman A, Guceri S, Sun W. 2008. Effect of dielectric barrier discharge plasma on the attachment and proliferation of osteoblasts cultured over poly(caprolactone) scaffolds. Plasma Process Polym 5(1): 58-66.
146. Yu ZK, He SB, Sun JW, Wang YF, Hu YM, Ping Q, Li XG, Xu WQ, Wang SJ. 2011. Complication following gastric pull-up reconstruction for advanced hypopharyngeal or cervical esophageal carcinoma: A 20-year review in a Chinese institute. Am J Otolaryngol 32(4): 275-278.
147. Zeltinger J, Sherwood JK, Graham DA, Mueller R, Griffith LG. 2001. Effect of pore size and void fraction on cellular adhesion, proliferation, and matrix deposition. Tissue Eng 7(5): 557-572.
148. Zhu Y, Chan-Park MB, Chian KS. 2005a. The growth improvement of porcine esophageal smooth muscle cells on collagen-grafted poly(DL-lactide-co-glycolide) membrane. J Biomed Mater Res B 75(1): 193-199.
149. Zhu Y, Chan-Park MB, Chian KS. 2005b. Surface modification of poly(DL-lactide-co-glycolide) copolymer with covalently immobilized collagen for esophageal tissue engineering. Mater Sci Forum 29: 478-483.
150. Zhu Y, Chian KS, Chan-Park MB, Mhaisalkar PS, Ratner BD. 2006. Protein bonding on biodegradable poly(L-lactide-co-caprolactone) membrane for esophageal tissue engineering. Biomaterials 27(1): 68-78.
151. Zhu Y, Leong MF, Ong WF, Chan-Park MB, Chian KS. 2007. Esophageal epithelium regeneration on fibronectin grafted poly(L-lactide-co-caprolactone) (PLLC) nanofiber scaffold. Biomaterials 28(5): 861-868.
152. Zisch AH, Lutolf MP, Hubbell JA. 2003. Biopolymeric delivery matrices for angiogenic growth factors. Cardiovasc Pathol 12(6): 295-310.
153. Zisch AH, Ehrbar M, Metters A, Zammaretti P, Hubbell JA. 2005. Endothelial cell proliferation and progenitor maturation by fibrin-bound VEGF variants with differential susceptibilities to local cellular activity. J Control Release 101(1-3): 93-109.