Carane derivative stereoisomers of different local anaesthetic and antiplatelet activity similarly potentiate forskolin-stimulated cyclic AMP response and bind to β-adrenoceptors in the rat brain cortex

Journal of Pharmacy and Pharmacology

Volumn 56, Issue 11, 2004, Pages 1429-1434

  Librowski, Tadeusz ^a   Vetulani, Jerzy ^b   Nalepa, Irena ^b  

^a JAGIELLONIAN UNIVERSITY   (Poland)

^b INSTITUTE OF PHARMACOLOGY   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

4 (3 TERT BUTYLAMINO 2 HYDROXYPROPOXY) 2 BENZIMIDAZOLONE; ADENYLATE CYCLASE; ANTITHROMBOCYTIC AGENT; BETA ADRENERGIC RECEPTOR; CARANE DERIVATIVE; CYCLIC AMP; FORSKOLIN; KP 23; LIGAND; LOCAL ANESTHETIC AGENT; TRITIUM; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BINDING ASSAY; BINDING SITE; BIOSYNTHESIS; BRAIN CORTEX; BRAIN LEVEL; CHIRALITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISSOCIATION; DRUG CONFORMATION; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; LOCAL ANESTHESIA; MALE; NONHUMAN; RAT; STEREOISOMERISM; STRUCTURE ANALYSIS; THROMBOCYTE AGGREGATION INHIBITION;

ANESTHETICS, LOCAL; ANIMALS; CEREBRAL CORTEX; CYCLIC AMP; CYCLOHEXYLAMINES; FORSKOLIN; MALE; PLATELET AGGREGATION; RATS; RATS, WISTAR; RECEPTORS, ADRENERGIC, BETA; STEREOISOMERISM;

EID: 8144225322     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/0022357044742     Document Type: Article

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