Propranolol prevents the development of venous thrombosis in rats by a platelet-dependent mechanism

Polish Journal of Pharmacology

Volumn 53, Issue 1, 2001, Pages 5-10

  Gruszecki, M ^a   Rolkowski R ^a   Pawlak, R ^a   Buczko, W ^a  

^a MEDICAL UNIVERSITY OF BIALYSTOK   (Poland)

Author keywords

Platelet aggregation; Propranolol; Rat; Venous thrombosis

Indexed keywords

ADENOSINE DIPHOSPHATE; ANGIOTENSIN RECEPTOR ANTAGONIST; ANTIHYPERTENSIVE AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; PENTOBARBITAL; PROPRANOLOL; PROPRANOLOLUM HYDROCHLORICUM;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLEEDING TIME; CAVA VEIN; CONTROLLED STUDY; DRUG MECHANISM; EUGLOBULIN LYSIS TEST; INCIDENCE; MALE; NONHUMAN; PARTIAL THROMBOPLASTIN TIME; PROTHROMBIN TIME; RAT; SYSTOLIC BLOOD PRESSURE; THROMBOCYTE AGGREGATION; THROMBUS; VEIN LIGATION; VEIN THROMBOSIS;

ANIMALS; ANTIHYPERTENSIVE AGENTS; BLEEDING TIME; BLOOD PRESSURE; HEMOSTASIS; MALE; PLATELET AGGREGATION; PROPRANOLOL; RATS; RATS, WISTAR; VENOUS THROMBOSIS;

EID: 0035066992     PISSN: 12306002     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Influence of propranolol on platelet aggregation and thromboxane B2 production from platelet-rich plasma and whole blood
2. Effects of the numbers and sizes of platelet aggregates on the optical density of plasma
3. Age and 5HT2-receptor blockade with ketanserin in essential hypertension
4. Effects of drugs affecting the renin-angiotensin system on venous thrombosis in normotensive rats
5. The antithrombotic effect of captopril and losartan on experimental arterial thrombosis in rats
6. Losartan inhibits experimental venous thrombosis in spontaneously hypertensive rats
7. Antithrombotic activity of losartan in two kidneys, one clip hypertensive rats. A study on the mechanism of action
8. The role of serotonin in thrombogenesis
9. Bleeding time in laboratory animals. II- A comparison of different assay conditions in rats
10. Comparison of the effects of carvedilol, propranolol, and verapamil on in vitro platelet function in healthy volunteers
11. Thrombolytic activity of beta-adrenolytic drug, sotalol
12. Sodium nitroprusside modulates the fibrinolytic system in the rabbit
13. Interactions of carteolol and other beta-adrenoceptor blocking agents with serotonin receptor subtypes
14. Nitric oxide and prostacyclin are involved in antithrombotic action of captopril in venous thrombosis in rats
15. Thiol repletion prevents venous thrombosis in rats by nitric oxide/prostacy-clin-dependent mechanism: Relation to the antithrombotic action of captopril
16. Prevention of pulmonary embolism and deep vein thrombosis with low dose aspirin
17. Venostasis-induced thrombosis in rats is not influenced by circulating platelet or leukocyte number
18. Serotonin and the blood-vessel wall
19. Endothelium-dependent effects of beta-adrenergic blockers
20. Effect of propranolol on platelet function
21. Platelet function and fibrinolytic activity in hypertension: Differential effects of calcium antagonists and beta-adrenergic receptor blockers
22. A low cost tail-cuff method for the estimation of mean arterial pressure in conscious rats