Estimation of the RBE of mammography-quality beams using a combination of a Monte Carlo code with a B-DNA geometrical model

Physics in Medicine and Biology

Volumn 56, Issue 23, 2011, Pages 7393-7403

  Bernal, M A ^a,b   Dealmeida, C E ^a   David, M ^a   Pires, E ^a  

^a STATE UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

DAMAGE PROBABILITY; GENETIC MATERIALS; GEOMETRICAL MODELS; HOMOGENEOUS MEDIUM; LIQUID WATER; LOW-ENERGY X-RAYS; MONTE CARLO CODES; ORGANIZATIONAL LEVELS; PENELOPE CODE; RADIATION QUALITY; RELATIVE BIOLOGICAL EFFECTIVENESS; STRAND BREAKS; X RAY BEAM; X-RAY ENERGIES;

CODES (SYMBOLS); GEOMETRY; PHOTONS; X RAYS;

GENE ENCODING;

DNA B;

ARTICLE; DNA DAMAGE; GENETICS; IMAGE QUALITY; MAMMOGRAPHY; METABOLISM; METHODOLOGY; MONTE CARLO METHOD; RELATIVE BIOLOGIC EFFECTIVENESS;

DNA DAMAGE; DNA, B-FORM; MAMMOGRAPHY; MONTE CARLO METHOD; PHANTOMS, IMAGING; RELATIVE BIOLOGICAL EFFECTIVENESS;

EID: 81355164260     PISSN: 00319155     EISSN: 13616560     Source Type: Journal    
DOI: 10.1088/0031-9155/56/23/004     Document Type: Article

References (33)

1. Bernal M A, de Almeida C E, Sampaio C, Incerti S, Champion C and Nieminen P 2011 The invariance of the total direct DNA strand break yield Med. Phys. 38 4147-53
2. Bernal M A and Liendo J A 2009 An investigation on the capabilities of the PENELOPE MC code in nanodosimetry Med. Phys. 36 620-5
3. Brenner D J and Amols H I 1989 Enhanced risk from low-energy screen-film mammography x-rays Br. J. Radiol. 62 910-4 (Pubitemid 19254199)
4. David M G, Pires E J, Bernal M A, Peixoto J P G and deAlmeida C E 2011 Experimental and Monte Carlo-simulated spectra of standard mammography-quality beams Br. J. Radiol. doi:10.1259/bjr/73088072
5. Dingfelder M, Hantke D and Inokuti M 1998 Electron inelastic scattering cross sections in liquid water Radiat. Phys. Chem. 53 1-18 (Pubitemid 28293702)
6. Frankenberg D, Brede H J, Schrewe U J, Steinmetz C, Frankenberg-Schwager M, Kasten G and Pralle E 2000 Induction of DNA double-strand breaks in mammalian cells and yeast Adv. Space Res. 25 2085-94
7. Frankenberg D, Kelnhofer K, Bär K and Frankenberg-Schwager M 2002 Enhanced neoplastic transformation by mammography x-rays relative to 200 kVp x-rays: indication for a strong dependence on photon energy of the RBEM for various end points Radiat. Res. 157 99-105 (Pubitemid 34073393)
8. Friedland W, Bernhardt P, Jacob P, Paretzke H G and Dingfelder M 2003 Simulation of DNA damage after proton and low LET irradiation Radiat. Res. 99 99-102
9. Friedland W, Jacob P, Paretzke H G, Merzagora M and Ottolenghi A 1999 Simulation of DNA fragment distributions after irradiation with photons Radiat. Environ. Biophys. 38 39-47 (Pubitemid 29272848)
10. Friedland W, Jacob P, Paretzke H G and Stork T 1998 Monte Carlo simulation of the production of short DNA fragments by low-linear energy transfer radiation usin high-order DNA molecules Radiat. Res. 150 170-82 (Pubitemid 28347977)
11. Friedland W, Jacob P, Paretzke H G, Ottolenghi A, Ballarini F and Liotta M 2006 Simulation of light ion induced DNA damage patterns Radiat. Prot. Dosim. 122 116-20 (Pubitemid 47090435)
12. Göggelmann W, Jacobsen C, Panzer W, Walsh L, Roos H and Schmid E 2003 Re-evaluation of the RBE of 29 kV x-rays (mammography x-rays) relative to 220 kV x-rays using neoplastic transformation of human CGL1-hybrid cells Radiat. Environ. Biophys. 42 175-82 (Pubitemid 37518061)
13. Hsiao Y and Stewart R D 2008 Monte Carlo simulation of DNA damage induction by x-rays and selected radioisotopes Phys. Med. Biol. 53 233-44
14. Hunter N and Muirhead C R 2009 Review of relative biological effectiveness dependence on linear energy transfer for low-LET radiations J. Radiol. Prot. 29 5-21
15. ICRU 1986 The quality factor in radiation protection Technical Report 40 (Bethesda, MD: ICRU)
16. Kellerer A M 2002 Electron spectra and the RBE of x-rays Radiat. Res. 158 13-22
17. 60Co rays Radiat. Res. 164 669-76
18. Lehnert A, Lessmann E, Pawelke J and Dörr W 2006 RBE of 25 kV x-rays for the survival and induction of micronuclei in the human mammary epithelial cell line MCF-12a Radiat. Environ. Biophys. 45 253-60 (Pubitemid 44764267)
19. Lehnert A, Dörr W, Lessmann E and Pawelke J 2008 RBE of 10 kV x-rays determined for the human mammary epithelial cell line MCF-12a Radiat. Res. 169 330-6 (Pubitemid 351521768)
20. Mestres M, Caballín M R, Barrios L, Ribas M and Barquinero J F 2009 RBE of x-rays of different energies: a cytogenetic evaluation by FISH Radiat. Res. 170 93-100 (Pubitemid 351931191)
21. Nikjoo H and Goodhead D T 1991 Track structure analysis illustrating the prominent role of low-energy electrons in radiobiological effects of low-LET radiation Phys. Med. Biol. 36 229
22. Nikjoo H, Goodhead D T, Charlton D E and Paretzke H G 1991 Energy deposition in small cylindrical targets by monoenergetic electrons Int. J. Radiat. Biol. 60 739-56
23. Nikjoo H, O'Neill P, Wilson W E and Goodhead D T 2001 Computational approach for determining the spectrum of DNA damage induced by ionizing radiation Radiat. Res. 156 577-83 (Pubitemid 33027531)
24. Panajotovic R, Martin F, Cloutier P, Hunting D and Sanche L 2006 Effective cross sections for production of single-strand breaks in plasmid DNA by 0.1 to 4.7 eV electrons Radiat. Res. 165 452-9
25. Pomplun E 1991 A new DNA target model for track structure calculations and its first application to I-125 auger electrons Int. J. Radiat. Biol. 59 625-42
26. Prise K M et al 1998 A review of DSB induction data for varying quality radiations Int. J. Radiat. Biol. 74 173-84 (Pubitemid 28372545)
27. Salvat F, Fernandez-Varea J M and Sempau J 2008 A code system for Monte Carlo simulation of electron and photon transport Technical Report (Issy-les-Moulineaux: OECD-NEA)
28. Schmid E, Regulla D, Kramer H M and Harder D 2002 The effect of 29 kV x-rays on the dose response of chromosome aberrations in human lymphocytes Radiat. Res. 158 771-7 (Pubitemid 35429972)
29. Schmid E, Krumrey M, Ulm G, Roos H and Regulla D 2003 The maximum low-dose RBE of 17.4 and 40 keV monochromatic x-rays for the induction of dicentric chromosomes in human peripheral lymphocytes Radiat. Res. 160 499-504 (Pubitemid 38055196)
30. Semenenko V A and Stewart R D 2004 A fast Monte Carlo algorithm to simulate the spectrum of DNA damages formed by ionizing radiation Rad. Res. 161 451-7 (Pubitemid 40754242)
31. Semenenko V A and Stewart R D 2006 Fast Monte Carlo simulation of DNA damage formed by electrons and light ions Phys. Med. Biol. 51 1693-706
32. Stewart R D, Wilson W E, McDonald J C and Strom D J 2002 Microdosimetric properties of ionizing electrons in water: a test of the PENELOPE code system Phys. Med. Biol. 47 77-88
33. Verhaegen F and Reniers B 2004 Microdosimetric analysis of various mammography spectra: lineal energy distributions and ionization cluster analysis Radiat. Res. 162 592-9 (Pubitemid 39600549)