Efficacy of plasma rich in growth factors for the treatment of dry eye

Cornea

Volumn 30, Issue 12, 2011, Pages 1312-1317

  López Plandolit, Silvia ^a   Morales, María Celia ^a   Freire, Vanesa ^a   Grau, Arturo E ^a   Durán, Juan A ^a  

^a Instituto Clínico Quirúrgico Oftalmológico   (Spain)

Author keywords

dry eye; growth factors; impression cytology; plasma; questionnaire; squamous metaplasia

Indexed keywords

EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR; VASCULOTROPIN;

ADULT; AGED; ARTICLE; BLURRED VISION; CLINICAL ARTICLE; CLINICAL EVALUATION; CONTROLLED STUDY; CYTOPATHOLOGY; DISEASE SEVERITY; DRUG EFFICACY; DRY EYE; EYE PAIN; FEMALE; FOLLOW UP; HUMAN; LAMINAR FLOW; MALE; OCULAR PRURITUS; PHOTOSENSITIVITY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; QUESTIONNAIRE; SCORING SYSTEM; SQUAMOUS CELL METAPLASIA; THERAPY EFFECT;

ADULT; AGED; CONJUNCTIVA; DRY EYE SYNDROMES; FEMALE; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; METAPLASIA; MIDDLE AGED; OPHTHALMIC SOLUTIONS; PLASMA; TEARS;

EID: 81355160252     PISSN: 02773740     EISSN: 15364798     Source Type: Journal    
DOI: 10.1097/ICO.0b013e31820d86d6     Document Type: Article

References (28)

1. Pflugfelder SC, Solomon A, Stern ME. The diagnosis and management of dry eye: a twenty five year review. Cornea. 2000;19:644-649.
2. Tseng SC, Tsubota K. Important concepts for treating ocular surface and tear disorders. Am J Ophthalmol. 1997;124:825-835.
3. Klenkler B, Sheardown H, Jones L. Growth factors in the tear film: role in tissue maintenance, wound healing and ocular pathology. Ocul Surf. 2007; 5:228-239.
4. Fox RI, Chan R, Michelson JB, et al. Beneficial effect of artificial tears made with autologous serum in patients with keratoconjunctivitis sicca. Arthritis Rheu. 1984;27:459-461.
5. Tsubota K, Goto E, Fujita H, et al. Treatment of dry eye by autologous serum application in Sjögren's syndrome. Br J Ophthalmol. 1999;83: 390-395.
6. Poon AC, Geerling G, Dart JK. Autologous serum eye drops for dry eye and epithelial defects: clinical and in vitro toxicity studies. Br J Ophthalmol. 2001;85:1188-1197.
7. Tananuvat N, Daniell M, Sullivan LJ, et al. Controlled study of the use of autologous serum in dry eye patients. Cornea. 2001;20:802-806.
8. Kojima T, Ishida R, Dogru M, et al. The effect of autologous serum eye drops in the treatment of severe dry eye disease: a prospective randomized case-control study. Am J Ophthalmol. 2005;139:242-246.
9. Anitua E. Plasma rich in growth factors: preliminary results of use in the preparation of future sites for implants. Int J Oral Maxillofac Implants. 1999;14:529-535.
10. Anitua E, And́a I, Ardanza B, et al. Autologous platelets as a source of protein for healing and tissue regeneration. Thromb Haemost. 2004;91: 4-15.
11. Anitua E, And́a I, Sánchez M, et al. Autologous preparation rich in growth factors promote proliferation and induce VEGF and HGF production by human tendon cells in culture. J Orthop Res. 2005;23:281-286.
12. Rocha G, Acera A, Durán JA. Laser in situ keratomileusis flap necrosis after trigeminal nerve palsy. Arch Ophthalmol. 2007;125: 1423-1425.
13. López-Plandolit S, Morales MC, Freire V, et al. Plasma rich in growth factors (PRGF) as a therapeutic agent for severe persistent corneal epithelial defects. Cornea. 2010;29:843-848.
14. Garća-Catalan MR, Jerez-Oliveira E, Benitez del Castillo JM. Dry eye and quality of life. Arch Soc Esp Oftalmol. 2009;84:451-458.
15. Begley CG, Caffery B, Chalmers RL, et al. Use of the dry eye questionnaire to measure symptoms of ocular irritation in patients with aqueous tear deficient dry eye. Cornea. 2002;21:664-670.
16. van Bijsterveld OP. Diagnostic tests in the sicca syndrome. Arch Ophthalmol. 1969;82:10-14.
17. Rivas L. Diagnosis through other assays. In: Murube J, Rolando M, eds. Dry Eye: A Systematic Approach to Therapy Ciba Vision. Ocular Surface Diseases-Study Group; 1999:101-114.
18. Oroza MA. Estudio Inmunohistoqúmico y Morfológico En ojos de Pacientes con Śndrome de Sjógren [doctoral thesis]. Madrid, Spain: Complutense University; 2000.
19. Murube J. Clasificación cĺnica del ojo seco. In: Murube J, ed. Ojo Seco-Dry Eye. Madrid, Spain: Tecnimedia Editorial; 1997:39-44.
20. Lemp MA. The definition and classification of dry eye disease: report of the definition and classification subcommittee of the international dry eye workshop. Ocul Surf. 2007;5:75-92.
21. Pflugfelder S, Tseng S, Sanabria O. Evaluation of subjective assessments and objective diagnostic tests for diagnosing tear-film disorders known to cause ocular irritation. Cornea. 1998;17:38-56.
22. Schein O, Tielsch J, Munõz B. Relationship between signs and symptoms of dry eye in the elderly. A population-based perspective. Ophthalmology. 1997;104:1395-1401.
23. Tomlinson A, Thai L, Doane M. Reliability of measurements of tear physiology. Adv Exp Med Biol. 2002;506:1097-1105.
24. Adams J,Wilcox M, Trousdale M. Morphologic and physiologic effects of artificial tear formulations on corneal epithelial derived cells. Cornea. 1992;11:234-241.
25. Harwig D, Harloff S, Liu L, et al. Epitheliotropic capacity of a growth factor preparation produced from platelet concentrates on corneal epithelial cells: a potential agent for the treatment of ocular surface defects? Transfusion. 2004;44:1724-1731.
26. Alio JL, Colecha JR, Pastor S, et al. Symptomatic dry eye treatment with autologous platelet-rich plasma. Ophthalmic Res. 2007;39:124-129.
27. Vajpayee RB, Mukerji N, Tandon R, et al. Evaluation of umbilical cord serum therapy for persistent corneal epithelial defects. Br J Ophthalmol. 2003;87:1312-1316.
28. Durán JA, López-Plandolit S, Freire V, et al. Characterization of different plasma-derived preparations used as corneal reepithelization inductors. Poster presented at: ARVO Annual Meeting May 3-7, 2009, Fort Lauderdale, FL.