Amniotic fluid chemokines and autism spectrum disorders: An exploratory study utilizing a Danish Historic Birth Cohort

Brain, Behavior, and Immunity

Volumn 26, Issue 1, 2012, Pages 170-176

  Abdallah, Morsi W ^a,b,c   Larsen, Nanna ^b   Grove, Jakob ^d   Nørgaard Pedersen, Bent ^b   Thorsen, Poul ^e   Mortensen, Erik L ^c   Hougaard, David M ^b  

^a AARHUS UNIVERSITY   (Denmark)

^b STATENS SERUM INSTITUT   (Denmark)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

^d AARHUS UNIVERSITY   (Denmark)

^e KOLDING HOSPITAL   (Denmark)

Author keywords

Amniotic fluid; Autistic disorder; Chemokine; MCP 1; Population register

Indexed keywords

MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MONOCYTE CHEMOTACTIC PROTEIN 1; RANTES;

ADULT; AMNION FLUID; AMNION FLUID ANALYSIS; ARTICLE; ASPERGER SYNDROME; AUTISM; CASE CONTROL STUDY; CHILD; CONTROLLED STUDY; DISEASE ASSOCIATION; EXPLORATORY RESEARCH; FEMALE; HUMAN; INFANTILE AUTISM; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RISK FACTOR; SCHOOL CHILD;

ADULT; AMNIOTIC FLUID; CASE-CONTROL STUDIES; CHEMOKINE CCL2; CHEMOKINE CCL3; CHEMOKINE CCL5; CHEMOKINES; CHILD; CHILD DEVELOPMENT DISORDERS, PERVASIVE; COHORT STUDIES; CONGENITAL ABNORMALITIES; DENMARK; FEMALE; GESTATIONAL AGE; HUMANS; INTERNATIONAL CLASSIFICATION OF DISEASES; LOGISTIC MODELS; MATERNAL AGE; MENTAL DISORDERS; ODDS RATIO; PREGNANCY;

EID: 81355146671     PISSN: 08891591     EISSN: 10902139     Source Type: Journal    
DOI: 10.1016/j.bbi.2011.09.003     Document Type: Article

References (53)

1. Agergaard P., Hebert A., Bjerre J., Sorensen K.M., Olesen C., Ostergaard J.R. Children diagnosed with congenital cardiac malformations at the national university departments of pediatric cardiology: positive predictive values of data in the Danish National Patient Registry. Clin. Epidemiol. 2011, 3:61-66.
2. American Psychiatric Association. 2000. Diagnostic and Statistical Manual of Mental Disorders. American Psychiatric Publishing, Inc.
3. Andersen T.F., Madsen M., Jorgensen J., Mellemkjoer L., Olsen J.H. The Danish National Hospital Register. A valuable source of data for modern health sciences. Dan. Med. Bull. 1999, 46(3):263-268.
4. Ashdown H., Dumont Y., Ng M., Poole S., Boksa P., Luheshi G.N. The role of cytokines in mediating effects of prenatal infection on the fetus: implications for schizophrenia. Mol. Psychiatry 2006, 11(1):47-55.
5. Ashwood P., Krakowiak P., Hertz-Picciotto I., et al. Associations of impaired behaviors with elevated plasma chemokines in autism spectrum disorders. J. Neuroimmunol. 2011, 232(1-2):196-199.
6. Atladottir HO, Thorsen P, Schendel D, Ostergaard L, Abdallah M, Lemcke S et al.. Maternal infection requiring hospitalization during pregnancy and autism spectrum disorders. Journal of Autism and Developmental Disordorder [Internet].
7. Biber K., Vinet J., Boddeke H.W.G.M. Neuron-microglia signaling: Chemokines as versatile messengers. J. Neuroimmunol. 2008, 198(1-2):69-74.
8. Brown A.S., Hooton J., Schaefer C.A., Zhang H., Petkova E., Babulas V., et al. Elevated maternal interleukin-8 levels and risk of schizophrenia in adult offspring. Am. J. Psychiatry 2004, 161(5):889-895.
9. Chow S.S.W., Craig M.E., Jones C.A., Hall B., Catteau J., Lloyd A.R., et al. Differences in amniotic fluid and maternal serum cytokine levels in early midtrimester women without evidence of infection. Cytokine 2008, 44(1):78-84.
10. Conductier G., Blondeau N., Guyon A., Nahon J.-L., Rovère C. The role of monocyte chemoattractant protein MCP1/CCL2 in neuroinflammatory diseases. J. Neuroimmunol. 2010, 224(1-2):93-100.
11. Epstein F.H., Luster A.D. Chemokines - chemotactic cytokines that mediate inflammation. N. Engl. J. Med. 1998, 338(7):436-445.
12. Esplin M.S., Romero R., Chaiworapongsa T., Kim Y.M., Edwin S., Gomez R., et al. Monocyte chemotactic protein-1 is increased in the amniotic fluid of women who deliver preterm in the presence or absence of intra-amniotic infection. J. Maternal-Fetal Neonatal Med. 2005, 17(6):365-373.
13. Ganz M. The Costs of Autism. Understanding Autism: From Basic Neuroscience to Treatment. First ed. Boca Raton 2006, Taylor and Francis Group, LLC, Boca Raton, FL. S.O. Moldin, J.L.R. Rubenstein (Eds.).
14. Goines P., Van de Water J. The immune system's role in the biology of autism. Curr. Opin. Neurol. 2010, 23(2):111.
15. Gomez-Lopez N., Laresgoiti-Servitje E., Olson D.M., Estrada-Gutiérrez G., Vadillo-Ortega F. The role of chemokines in term and premature rupture of the fetal membranes: a review. Biol. Reprod. 2010, 82(5):809-814.
16. Hesselgesser J., Horuk R. Chemokine and chemokine receptor expression in the central nervous system. Journal of Neurovirology 1999, 5(1):13-26.
17. Heuer L., Ashwood P., Van de Water J. The immune system in autism, Is there a connection?. Autism: Current Theories and Evidence (Current Clinical Neurology) 2008, Humana Press, Totowa. A.W. Zimmerman (Ed.).
18. Holst R.-M., Laurini R., Jacobsson B., Samuelsson E., Sävman K., Doverhag C., et al. Expression of cytokines and chemokines in cervical and amniotic fluid: relationship to histological chorioamnionitis. J. Matern Fetal Neonatal Med. 2007, 20(12):885-893.
19. Kayisli U.A., Mahutte N.G., Arici A. Uterine Chemokines in Reproductive Physiology and Pathology. Am. J. Reprod. Immunol. 2002, 47(4):213-221.
20. Knudsen L., Olsen J. The Danish Medical Birth Registry. Dan. Med. Bull. 1998, 45(3):320.
21. Kugler K., Hackl W., Mueller L., et al. The impact of sample storage time on estimates of association in biomarker discovery studies. J. Clin. Bioinform. 2011, 1(1):1-8.
22. Larsson H.J., Eaton W.W., Madsen K.M., Vestergaard M., Olesen A.V., Agerbo E., et al. Risk factors for autism perinatal factors parental psychiatric history and socioeconomic status. Am. J. Epidemiol. 2005, 161(10):916-925.
23. Lauritsen M., Jørgensen M., Madsen K., Lemcke S., Toft S., Grove J., et al. Validity of childhood autism in the Danish Psychiatric Central Register: findings from a cohort sample born 1990-1999. J. Autism Dev. Disord. 2010, 40(2):139-148.
24. Lauritsen M.B., Pedersen C.B., Mortensen P.B. The incidence and prevalence of pervasive developmental disorders: a Danish population-based study. Psychol. Med. 2004, 34(07):1339-1346.
25. Mahad D.J., Ransohoff R.M. The role of MCP-1 (CCL2) and CCR2 in multiple sclerosis and experimental autoimmune encephalomyelitis (EAE). Semin. Immunol. 2003, 15(1):23-32.
26. Mantovani A., Locati M., Sozzani S. CC Chemokines. The Cytokine Handbook 2003, 1083-1100. Academic Press Limited, London. 4th ed. A. Thomson, M.T. Lotze (Eds.).
27. Meyer U, Feldon J, Damman O. 2011. Schizophrenia and Autism: Both Shared and Disorder-Specific Pathogenesis Via Perinatal Inflammation? Pediatric Research 69(5 Part 2):26R-33R 10.1203/PDR.0b013e318212c196.
28. Munk-Jorgensen P., Mortensen P.B. The Danish Psychiatric Central Register. Dan. Med. Bull. 1997, 44(1):82-84.
29. Nahmias AJ, Nahmias SB, Danielsson D. 2006. The possible role of transplacentally-acquired antibodies to infectious agents with molecular mimicry to nervous system sialic acid epitopes as causes of neuromental disorders prevention and vaccine implications. Clinical and Developmental Immunology (13):167-183.
30. Newschaffer C.J., Croen L.A., Daniels J., Giarelli E., Grether J.K., Levy S.E., et al. The epidemiology of autism spectrum disorders. Annu. Rev. Public Health 2007, 28:235-258.
31. Nørgaard-Pedersen B. Statens Serum Institut: Etablering af en ny historisk prospektiv mor-barn biobank kohorte baseret på ca. 100.000 gravidscreenings prøver [Grant Application: Establishing a new historic prospective mother-child cohort based on approximately 100, 000 antenatal screening samples at Statens Serum Institut] 2005, Statens Sundhedsvidenskabelige Forskningsråd, Copenhagen.
32. Norgaard-Pedersen B., Bagger P., Bang J., Fischer-Rasmussen W., Gad C., Hasch E., et al. Maternal-serum-alphafetoprotein screening for fetal malformations in 28062 pregnancies: a four-year experience from a low-risk area. Acta Obstet. Gynecol. Scand. 1985, 64(6):511-514.
33. Norgaard-Pedersen B, Bagger PV, Bang J, Fischer-Rasmussen W, Gad C, Hasch E et al. 1984. Screening for serum alpha-fetoprotein for detection of congenital deformities in the 16th-18th weeks of pregnancy (In Danish). Ugeskr Laeger (146):3253-3259.
34. Nørgaard-Pedersen B., Hougaard D. Storage policies and use of the Danish Newborn Screening Biobank. J. Inherit. Metab. Dis. 2007, 30(4):530-536.
35. Pardo C.A., Vargas D.L., Zimmerman A.W. Immunity, neuroglia and neuroinflammation in autism. Int. Rev. Psychiatry 2005, 17(6):485-495.
36. Parner E.T., Schendel D.E., Thorsen P. Autism prevalence trends over time in Denmark: changes in prevalence and age at diagnosis. Arch. Pediatr. Adolesc. Med. 2008, 162(12):1150-1156.
37. Parsadaniantz SM, Banisadr G, Sarret P, Rostène W. 2010. Chemokines and Chemokine Receptors in the Brain. In: Meucci O, (ed.), Chemokine Receptors and NeuroAIDS. Springer New York. pp. 173-189.
38. Pedersen C., Gøtzsche H., Møller J., Mortensen P. The Danish civil registration system. Dan. Med. Bull. 2006, 53(4):441-449.
39. Rebenko-Moll N.M., Liu L., Cardona A., Ransohoff R.M. Chemokines, mononuclear cells and the nervous system: heaven (or hell) is in the details. Curr. Opin. Immunol. 2006, 18(6):683-689.
40. Rice C. Prevalence of Autism Spectrum Disorders: Autism and Developmental Disabilities Monitoring Network, Six Sites, United States, 2000 2007, CDC, Atlanta.
41. Rollins B.J. Monocyte chemoattractant protein 1: a potential regulator of monocyte recruitment in inflammatory disease. Mol. Med. Today 1996, 2(5):198-204.
42. Rostène W., Guyon A., Kular L., Godefroy D., Barbieri F., Bajetto A., et al. Chemokines and chemokine receptors: new actors in neuroendocrine regulations. Front. Neuroendocrinol. 2011, 32(1):10-24.
43. Rostène W., Kitabgi P., Mélik Parsadaniantz S. Chemokines: a new class of neuromodulator?. Nat. Rev. Neurosci. 2007, 8(11):895-903.
44. Schlotz W., Phillips D.I.W. Fetal origins of mental health: evidence and mechanisms. Brain Behav. Immun. 2009, 23(7):905-916.
45. Skogstrand K., Thorsen P., Norgaard-Pedersen B., Schendel D.E., Sorensen L.C., Hougaard D.M. Simultaneous measurement of 25 inflammatory markers and neurotrophins in neonatal dried blood spots by immunoassay with xMAP technology. Clin. Chem. 2005, 51(10):1854-1866.
46. SPSS Inc. 2009. IBM PASW® Statistics 18 (SPSS Statistics 18). 18 ed. Chicago, IL.
47. Stamatovic S.M., Shakui P., Keep R.F., Moore B.B., Kunkel S.L., Van Rooijen N., et al. Monocyte chemoattractant protein-1 regulation of blood-brain barrier permeability. J. Cereb. Blood Flow Metab. 2005, 25(5):593-606.
48. StataCorp LP. 2009. Stata Statistics/Data Analysis 11.2 ed. College Station, TX.
49. Stotz-Ingenlath G. Epistemological aspects of Eugen Bleuler's conception of Schizophrenia in 1911. Medicine. Health Care Philos. 2000, 3(2):153-159.
50. Sundhedsstyrelsen Klassifikation af Sygdomme [Danish-Latin Version of International Classification of Diseases, 8th Revision, 1965] 1986, The Danish National Board of Health, Copenhagen.
51. Sundhedsstyrelsen. Klassifikation af Sygdomme [Danish Version of International Classification of Diseases, 10th Revision] [Internet]. Copenhagen: The Danish National Board of Health. Available from: http://www.medinfo.dk/sks/brows.php?s_nod=4638.
52. Vargas D.L., Nascimbene C., Krishnan C., Zimmerman A.W., Pardo C.A. Neuroglial activation and neuroinflammation in the brain of patients with autism. Ann. Neurol. 2005, 57(1):67-81.
53. Zhen Meng S., Oka A., Takashima S. Developmental expression of monocyte chemoattractant protein-1 in the human cerebellum and brainstem. Brain Develop. 1999, 21(1):30-35.