MRP8/14 is associated with systemic inflammation in stable coronary atherosclerosis in men

European Journal of Clinical Investigation

Volumn 41, Issue 12, 2011, Pages 1261-1267

  Baumann, Marcus ^a   Schmaderer, Christoph ^a   Burkhardt, Klaus ^b   Haller, Bernhard ^c   Heemann, Uwe ^a   Dugi, Klaus ^d   von Eynatten, Maximilian ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b Nephrological Clinic Weissenburg   (Germany)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^d UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

Author keywords

Biomarker; Coronary artery disease; Inflammation; Male; MRP8 14; Risk factors

Indexed keywords

C REACTIVE PROTEIN; CALGRANULIN A; CALGRANULIN B; FIBRINOGEN; INTERLEUKIN 6;

ADULT; AGED; ANGIOCARDIOGRAPHY; ARTICLE; CARDIOVASCULAR RISK; CONTROLLED STUDY; CORONARY ARTERY ATHEROSCLEROSIS; CROSS-SECTIONAL STUDY; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FIBRINOGEN BLOOD LEVEL; HUMAN; INFLAMMATION; MAJOR CLINICAL STUDY; MALE; OBSERVATIONAL STUDY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL;

AGED; BIOLOGICAL MARKERS; C-REACTIVE PROTEIN; CASE-CONTROL STUDIES; CORONARY ANGIOGRAPHY; CORONARY ARTERY DISEASE; CROSS-SECTIONAL STUDIES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FIBRINOGEN; HUMANS; INFLAMMATION; INTERLEUKIN-6; LEUKOCYTE L1 ANTIGEN COMPLEX; MALE; MIDDLE AGED; RISK FACTORS; SEVERITY OF ILLNESS INDEX; STATISTICS AS TOPIC;

EID: 81355138923     PISSN: 00142972     EISSN: 13652362     Source Type: Journal    
DOI: 10.1111/j.1365-2362.2011.02530.x     Document Type: Article

References (36)

1. D'Agostino RB Sr, Grundy S, Sullivan LM, Wilson P. Validation of the Framingham coronary heart disease prediction scores: results of a multiple ethnic groups investigation. JAMA 2001;286:180-7.
2. Fraker TD Jr, Fihn SD, Gibbons RJ, Abrams J, Chatterjee K, Daley J et al. 2007 chronic angina focused update of the ACC/AHA 2002 Guidelines for the management of patients with chronic stable angina: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines Writing Group to develop the focused update of the 2002 Guidelines for the management of patients with chronic stable angina. Circulation 2007;116:2762-72.
3. Helfand M, Buckley DI, Freeman M, Fu R, Rogers K, Fleming C et al. Emerging risk factors for coronary heart disease: a summary of systematic reviews conducted for the U.S. Preventive Services Task Force. Ann Intern Med 2009;151:496-507.
4. Libby P, Ridker PM, Hansson GK. Inflammation in atherosclerosis: from pathophysiology to practice. J Am Coll Cardiol 2009;54:2129-38.
5. Pouliot P, Plante I, Raquil MA, Tessier PA, Olivier M. Myeloid-related proteins rapidly modulate macrophage nitric oxide production during innate immune response. J Immunol 2008;181:3595-601.
6. Rammes A, Roth J, Goebeler M, Klempt M, Hartmann M, Sorg C. Myeloid-related protein (MRP) 8 and MRP14, calcium-binding proteins of the S100 family, are secreted by activated monocytes via a novel, tubulin-dependent pathway. J Biol Chem 1997;272:9496-502.
7. Hessian PA, Edgeworth J, Hogg N. MRP-8 and MRP-14, two abundant Ca(2+)-binding proteins of neutrophils and monocytes. J Leukoc Biol 1993;53:197-204.
8. Vogl T, Tenbrock K, Ludwig S, Leukert N, Ehrhardt C, van Zoelen MA et al. Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock. Nat Med 2007;13:1042-9.
9. Guignard F, Mauel J, Markert M. Identification and characterization of a novel human neutrophil protein related to the S100 family. Biochem J 1995;309(Pt 2):395-401.
10. Altwegg LA, Neidhart M, Hersberger M, Muller S, Eberli FR, Corti R et al. Myeloid-related protein 8/14 complex is released by monocytes and granulocytes at the site of coronary occlusion: a novel, early, and sensitive marker of acute coronary syndromes. Eur Heart J 2007;28:941-8.
11. Healy AM, Pickard MD, Pradhan AD, Wang Y, Chen Z, Croce K et al. Platelet expression profiling and clinical validation of myeloid-related protein-14 as a novel determinant of cardiovascular events. Circulation 2006;113:2278-84.
12. Viemann D, Strey A, Janning A, Jurk K, Klimmek K, Vogl T et al. Myeloid-related proteins 8 and 14 induce a specific inflammatory response in human microvascular endothelial cells. Blood 2005;105:2955-62.
13. Teigelkamp S, Bhardwaj RS, Roth J, Meinardus-Hager G, Karas M, Sorg C. Calcium-dependent complex assembly of the myeloic differentiation proteins MRP-8 and MRP-14. J Biol Chem 1991;266:13462-7.
14. Lemarchand P, Vaglio M, Mauel J, Markert M. Translocation of a small cytosolic calcium-binding protein (MRP-8) to plasma membrane correlates with human neutrophil activation. J Biol Chem 1992;267:19379-82.
15. Manitz MP, Horst B, Seeliger S, Strey A, Skryabin BV, Gunzer M et al. Loss of S100A9 (MRP14) results in reduced interleukin-8-induced CD11b surface expression, a polarized microfilament system, and diminished responsiveness to chemoattractants in vitro. Mol Cell Biol 2003;23:1034-43.
16. Nacken W, Roth J, Sorg C, Kerkhoff C. S100A9/S100A8: myeloid representatives of the S100 protein family as prominent players in innate immunity. Microsc Res Tech 2003;60:569-80.
17. Croce K, Gao H, Wang Y, Mooroka T, Sakuma M, Shi C et al. Myeloid-related protein-8/14 is critical for the biological response to vascular injury. Circulation 2009;120:427-36.
18. Burkhardt K, Schwarz S, Pan C, Stelter F, Kotliar K, Von Eynatten M et al. Myeloid-related protein 8/14 complex describes microcirculatory alterations in patients with type 2 diabetes and nephropathy. Cardiovasc Diabetol 2009;8:10.
19. Morrow DA, Wang Y, Croce K, Sakuma M, Sabatine MS, Gao H et al. Myeloid-related protein 8/14 and the risk of cardiovascular death or myocardial infarction after an acute coronary syndrome in the Pravastatin or Atorvastatin Evaluation and Infection Therapy: Thrombolysis in Myocardial Infarction (PROVE IT-TIMI 22) trial. Am Heart J 2008;155:49-55.
20. von Eynatten M, Schneider JG, Humpert PM, Kreuzer J, Kuecherer H, Katus HA et al. Serum adiponectin levels are an independent predictor of the extent of coronary artery disease in men. J Am Coll Cardiol 2006;47:2124-6.
21. von Eynatten M, Humpert PM, Bluemm A, Lepper PM, Hamann A, Allolio B et al. High-molecular weight adiponectin is independently associated with the extent of coronary artery disease in men. Atherosclerosis 2008;199:123-8.
22. Dugi KA, Brandauer K, Schmidt N, Nau B, Schneider JG, Mentz S et al. Low hepatic lipase activity is a novel risk factor for coronary artery disease. Circulation 2001;104:3057-62.
23. Wolk R, Berger P, Lennon RJ, Brilakis ES, Somers VK. Body mass index: a risk factor for unstable angina and myocardial infarction in patients with angiographically confirmed coronary artery disease. Circulation 2003;108:2206-11.
24. Adams MR, Nakagomi A, Keech A, Robinson J, McCredie R, Bailey BP et al. Carotid intima-media thickness is only weakly correlated with the extent and severity of coronary artery disease. Circulation 1995;92:2127-34.
25. Sullivan DR, Marwick TH, Freedman SB. A new method of scoring coronary angiograms to reflect extent of coronary atherosclerosis and improve correlation with major risk factors. Am Heart J 1990;119:1262-7.
26. Thomas L. Retrospective power analysis. Conserv Biol 1997;11:276-80.
27. O'Keefe D. A priori power, retrospective power, prospective power, achieved power: sorting out appropriate uses of statistical power analyses. Commun Methods Meas 2007;I:291-9.
28. Ionita MG, Catanzariti LM, Bots ML, de Vries JP, Moll FL, Kwan Sze S et al. High myeloid-related protein: 8/14 levels are related to an increased risk of cardiovascular events after carotid endarterectomy. Stroke 2010;41:2010-5.
29. Burkhardt K, Radespiel-Troger M, Rupprecht HD, Goppelt-Struebe M, Riess R, Renders L et al. An increase in myeloid-related protein serum levels precedes acute renal allograft rejection. J Am Soc Nephrol 2001;12:1947-57.
30. Ionita MG, Vink A, Dijke IE, Laman JD, Peeters W, van der Kraak PH et al. High levels of myeloid-related protein 14 in human atherosclerotic plaques correlate with the characteristics of rupture-prone lesions. Arterioscler Thromb Vasc Biol 2009;29:1220-7.
31. Rosenson RS, Koenig W. Utility of inflammatory markers in the management of coronary artery disease. Am J Cardiol 2003;92:10i-8i.
32. Barinas-Mitchell E, Cushman M, Meilahn EN, Tracy RP, Kuller LH. Serum levels of C-reactive protein are associated with obesity, weight gain, and hormone replacement therapy in healthy postmenopausal women. Am J Epidemiol 2001;153:1094-101.
33. Harja E, Bu DX, Hudson BI, Chang JS, Shen X, Hallam K et al. Vascular and inflammatory stresses mediate atherosclerosis via RAGE and its ligands in apoE-/- mice. J Clin Invest 2008;118:183-94.
34. Johansson F, Kramer F, Barnhart S, Kanter JE, Vaisar T, Merrill RD et al. Type 1 diabetes promotes disruption of advanced atherosclerotic lesions in LDL receptor-deficient mice. Proc Natl Acad Sci USA 2008;105:2082-7.
35. Schulze zur Wiesch A, Foell D, Frosch M, Vogl T, Sorg C, Roth J. Myeloid related proteins MRP8/MRP14 may predict disease flares in juvenile idiopathic arthritis. Clin Exp Rheumatol 2004;22:368-73.
36. Buckley DI, Fu R, Freeman M, Rogers K, Helfand M. C-reactive protein as a risk factor for coronary heart disease: a systematic review and meta-analyses for the U.S. Preventive Services Task Force. Ann Intern Med 2009;151:483-95.