High-molecular weight adiponectin is independently associated with the extent of coronary artery disease in men

Atherosclerosis

Volumn 199, Issue 1, 2008, Pages 123-128

  von Eynatten, Maximilian ^a,b   Humpert, Per M ^b   Bluemm, Annabelle ^c   Lepper, Philipp M ^d   Hamann, Andreas ^b   Allolio, Bruno ^c   Nawroth, Peter P ^b   Bierhaus, Angelika ^b   Dugi, Klaus A ^b  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c UNIVERSITY OF WÜRZBURG   (Germany)

^d UNIVERSITY OF BERN   (Switzerland)

Author keywords

Adiponectin; Atherosclerosis; Coronary artery disease; Risk factor

Indexed keywords

ADIPONECTIN;

ADULT; AGED; ANGIOCARDIOGRAPHY; ARTICLE; CARDIOVASCULAR RISK; CORONARY ARTERY ATHEROSCLEROSIS; CORONARY ARTERY DISEASE; CORRELATION ANALYSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; MAJOR CLINICAL STUDY; MALE; MOLECULAR WEIGHT; MULTIVARIATE LOGISTIC REGRESSION ANALYSIS; PREDICTIVE VALIDITY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; STATISTICAL SIGNIFICANCE;

ADIPONECTIN; ADULT; AGED; AGED, 80 AND OVER; CORONARY ANGIOGRAPHY; CORONARY ARTERY DISEASE; HUMANS; MALE; MIDDLE AGED; MOLECULAR WEIGHT; MULTIVARIATE ANALYSIS; REGRESSION ANALYSIS; RISK FACTORS; ROC CURVE; SEVERITY OF ILLNESS INDEX; SEX DISTRIBUTION;

EID: 45249083408     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2007.10.002     Document Type: Article

References (25)

1. Kumada M., Kihara S., Sumitsuji S., et al. Association of hypoadiponectinemia with coronary artery disease in men. Arterioscler Thromb Vasc Biol 23 (2003) 85-89
2. von Eynatten M., Schneider J.G., Humpert P.M., et al. Serum adiponectin levels are an independent predictor of the extent of coronary artery disease in men. J Am Coll Cardiol 47 (2006) 2124-2126
3. Kadowaki T., Yamauchi T., Kubota N., et al. Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome. J Clin Invest 116 (2006) 1784-1792
4. Kadowaki T., and Yamauchi T. Adiponectin and adiponectin receptors. Endocr Rev 26 (2005) 439-451
5. Pajvani U.B., Du X., Combs T.P., et al. Structure-function studies of the adipocyte-secreted hormone Acrp30/adiponectin. Implications for metabolic regulation and bioactivity. J Biol Chem 278 (2003) 9073-9085
6. Okamoto Y., Kihara S., Ouchi N., et al. Adiponectin reduces atherosclerosis in apolipoprotein E-deficient mice. Circulation 106 (2002) 2767-2770
7. Yamauchi T., Kamon J., Waki H., et al. Globular adiponectin protected ob/ob mice from diabetes and ApoE-deficient mice from atherosclerosis. J Biol Chem 278 (2003) 2461-2468
8. Shapiro L., and Scherer P.E. The crystal structure of a complement-1q family protein suggests an evolutionary link to tumor necrosis factor. Curr Biol 8 (1998) 335-338
9. Lara-Castro C., Luo N., Wallace P., Klein R.L., and Garvey W.T. Adiponectin multimeric complexes and the metabolic syndrome trait cluster. Diabetes 55 (2006) 249-259
10. Tonelli J., Li W., Kishore P., et al. Mechanisms of early insulin-sensitizing effects of thiazolidinediones in type 2 diabetes. Diabetes 53 (2004) 1621-1629
11. Kobayashi H., Ouchi N., Kihara S., et al. Selective suppression of endothelial cell apoptosis by the high molecular weight form of adiponectin. Circ Res 94 (2004) e27-e31
12. Bobbert T., Rochlitz H., Wegewitz U., et al. Changes of adiponectin oligomer composition by moderate weight reduction. Diabetes 54 (2005) 2712-2719
13. Iwao S., Iwao N., Muller D.C., et al. Does waist circumference add to the predictive power of the body mass index for coronary risk?. Obes Res 9 (2001) 685-695
14. Dugi K.A., Brandauer K., Schmidt N., et al. Low hepatic lipase activity is a novel risk factor for coronary artery disease. Circulation 104 (2001) 3057-3062
15. Wolk R., Berger P., Lennon R.J., Brilakis E.S., and Somers V.K. Body mass index: a risk factor for unstable angina and myocardial infarction in patients with angiographically confirmed coronary artery disease. Circulation 108 (2003) 2206-2211
16. Adams M.R., Nakagomi A., Keech A., et al. Carotid intima-media thickness is only weakly correlated with the extent and severity of coronary artery disease. Circulation 92 (1995) 2127-2134
17. Sullivan D.R., Marwick T.H., and Freedman S.B. A new method of scoring coronary angiograms to reflect extent of coronary atherosclerosis and improve correlation with major risk factors. Am Heart J 119 (1990) 1262-1267
18. Hara K., Horikoshi M., Yamauchi T., et al. Measurement of the high-molecular weight form of adiponectin in plasma is useful for the prediction of insulin resistance and metabolic syndrome. Diab Care 29 (2006) 1357-1362
19. Aso Y., Yamamoto R., Wakabayashi S., et al. Comparison of serum high-molecular weight (HMW) adiponectin with total adiponectin concentrations in type 2 diabetic patients with coronary artery disease using a novel enzyme-linked immunosorbent assay to detect HMW adiponectin. Diabetes 55 (2006) 1954-1960
20. Okamoto Y., Arita Y., Nishida M., et al. An adipocyte-derived plasma protein, adiponectin, adheres to injured vascular walls. Horm Metab Res 32 (2000) 47-50
21. Wang Y., Lam K.S., Chan L., et al. Post-translational modifications of the four conserved lysine residues within the collagenous domain of adiponectin are required for the formation of its high molecular weight oligomeric complex. J Biol Chem 281 (2006) 16391-16400
22. Xu A., Chan K.W., Hoo R.L., et al. Testosterone selectively reduces the high molecular weight form of adiponectin by inhibiting its secretion from adipocytes. J Biol Chem 280 (2005) 18073-18080
23. Inoue T., Kotooka N., Morooka T., et al. High molecular weight adiponectin as a predictor of long-term clinical outcome in patients with coronary artery disease. Am J Cardiol 100 (2007) 569-574
24. Avins A.L., and Browner Ws. Improving the prediction of coronary heart disease to aid in the management of high cholesterol levels: what a difference a decade makes. JAMA 279 (1998) 445-449
25. Folsom A.R., Chambless L.E., Ballantyne C.M., et al. An assessment of incremental coronary risk prediction using C-reactive protein and other novel risk markers: the atherosclerosis risk in communities study. Arch Intern Med 166 (2006) 1368-1373