Behavioral characterization of cereblon forebrain-specific conditional null mice: A model for human non-syndromic intellectual disability

Behavioural Brain Research

Volumn 226, Issue 2, 2012, Pages 428-434

  Rajadhyaksha, Anjali M ^a,b   Ra, Stephen ^a   Kishinevsky, Sarah ^b   Lee, Anni S ^a,b   Romanienko, Peter ^c   DuBoff, Mariel ^c   Yang, Chingwen ^d   Zupan, Bojana ^e   Byrne, Maureen ^a   Daruwalla, Zeeba R ^a,b   Mark, Willie ^c   Kosofsky, Barry E ^a,b   Toth, Miklos ^e   Higgins, Joseph J ^a  

^a NEW YORK PRESBYTERIAN HOSPITAL   (United States)

^b Weill Cornell Graduate School of Biomedical Sciences   (United States)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^d ROCKEFELLER UNIVERSITY   (United States)

^e WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Association learning; Cereblon; Conditional knock out mice; Fear conditioning; Memory; Non syndromic mental retardation

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CRE RECOMBINASE; MESSENGER RNA;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY; ARTICLE; BRAIN FUNCTION; BRAIN REGION; CEREBELLUM; CEREBLON GENE; CONDITIONING; CONTROLLED STUDY; EXON; EXPLORATORY BEHAVIOR; FEAR; FOREBRAIN; GENE ACTIVATION; GENE DELETION; GENE EXPRESSION; GENE FUNCTION; GENE IDENTIFICATION; GENE LOCATION; HIPPOCAMPUS; IN VIVO STUDY; INTELLECTUAL IMPAIRMENT; KNOCKOUT MOUSE; LEARNING DISORDER; LOCOMOTION; MARKER GENE; MEMORY DISORDER; MOTIVATION; MOTOR PERFORMANCE; MOUSE; NEOCORTEX; NONHUMAN; NULL ALLELE; PRIORITY JOURNAL; PROMOTER REGION; WILD TYPE;

ANIMALS; BASE SEQUENCE; CONDITIONING, CLASSICAL; DISEASE MODELS, ANIMAL; EXONS; FEAR; HUMANS; INTELLECTUAL DISABILITY; MALE; MAZE LEARNING; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MOTOR ACTIVITY; NERVE TISSUE PROTEINS; PROSENCEPHALON; SEQUENCE DELETION;

EID: 81355127289     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2011.09.039     Document Type: Article

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