메뉴 건너뛰기




Volumn 1, Issue 1, 2010, Pages 27-33

Beneficial effects of 2 years of administration of parenteral testosterone undecanoate on the metabolic syndrome and on non-alcoholic liver steatosis and C-reactive protein

Author keywords

aging; liver steatosis; metabolic syndrome; testosterone

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; C REACTIVE PROTEIN; CHOLESTEROL; GLUCOSE; HEMOGLOBIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PROSTATE SPECIFIC ANTIGEN; TESTOSTERONE; TESTOSTERONE UNDECANOATE; TRIACYLGLYCEROL;

EID: 81255202840     PISSN: 18681883     EISSN: 18681891     Source Type: Journal    
DOI: 10.1515/HMBCI.2010.002     Document Type: Article
Times cited : (4)

References (41)
  • 1
    • 26444515048 scopus 로고    scopus 로고
    • The decline of androgen levels in elderly men and its clinical and therapeutic implications
    • Kaufman JM., Vermeulen A. The decline of androgen levels in elderly men and its clinical and therapeutic implications. Endocr Rev 2005;26:833-76.
    • (2005) Endocr Rev , vol.26 , pp. 833-876
    • Kaufman, J.1    Vermeulen, A.2
  • 2
    • 10344243498 scopus 로고    scopus 로고
    • Prevalence and incidence of androgen deficiency in middle-aged and older men: estimates from the Massachusetts Male Aging Study
    • Araujo AB., O'Donnell AB., Brambilla DJ., Simpson WB., Long-cope C., Matsumoto AM., McKinlay JB. Prevalence and incidence of androgen deficiency in middle-aged and older men: estimates from the Massachusetts Male Aging Study. J Clin Endocrinol Metab 2004;89:5920-6.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 5920-5926
    • Araujo, A.1    O'Donnell, A.2    Brambilla, D.3    Simpson, W.4    Long-cope, C.5    Matsumoto, A.6    McKinlay, J.7
  • 3
    • 34548722899 scopus 로고    scopus 로고
    • Age-related changes in serum testosterone and sex hormone binding globulin in Australian men: longitudinal analyses of two geographically separate regional cohorts
    • Liu PY., Beilin J., Meier C., Nguyen TV., Center JR., Leedman PJ., Seibel MJ., Eisman JA., Handelsman DJ. Age-related changes in serum testosterone and sex hormone binding globulin in Australian men: longitudinal analyses of two geographically separate regional cohorts. J Clin Endocrinol Metab 2007;92:3599-603.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 3599-3603
    • Liu, P.1    Beilin, J.2    Meier, C.3    Nguyen, T.4    Center, J.5    Leedman, P.6    Seibel, M.7    Eisman, J.8    Handelsman, D.9
  • 4
    • 16644396636 scopus 로고    scopus 로고
    • Low testosterone is associated with decreased function and increased mortality risk: a preliminary study of men in a geriatric rehabilitation unit
    • Shores MM., Moceri VM., Gruenewald DA., Brodkin KI., Mat-sumoto AM., Kivlahan DR. Low testosterone is associated with decreased function and increased mortality risk: a preliminary study of men in a geriatric rehabilitation unit. J Am Geriatr Soc 2004;52:2077-81.
    • (2004) J Am Geriatr Soc , vol.52 , pp. 2077-2081
    • Shores, M.1    Moceri, V.2    Gruenewald, D.3    Brodkin, K.4    Mat-sumoto, A.5    Kivlahan, D.R.6
  • 7
    • 37349118353 scopus 로고    scopus 로고
    • Endogenous testosterone and mortality due to all causes, cardiovascular disease, and cancer in men: European prospective investigation into cancer in Norfolk (EPIC-Norfolk) Prospective Population Study
    • Khaw KT., Dowsett M., Folkerd E., Bingham S., Wareham N., Luben R., Welch A., Day N. Endogenous testosterone and mortality due to all causes, cardiovascular disease, and cancer in men: European prospective investigation into cancer in Norfolk (EPIC-Norfolk) Prospective Population Study. Circulation 2007;116:2694-701.
    • (2007) Circulation , vol.116 , pp. 2694-2701
    • Khaw, K.1    Dowsett, M.2    Folkerd, E.3    Bingham, S.4    Wareham, N.5    Luben, R.6    Welch, A.7    Day, N.8
  • 9
    • 33749065762 scopus 로고    scopus 로고
    • The effect of changes in adiposity on testosterone levels in older men: longitudinal results from the Massachusetts Male Aging Study
    • Mohr BA., Bhasin S., Link CL., O'Donnell AB., McKinlay JB. The effect of changes in adiposity on testosterone levels in older men: longitudinal results from the Massachusetts Male Aging Study. Eur J Endocrinol 2006;155:443-52.
    • (2006) Eur J Endocrinol , vol.155 , pp. 443-452
    • Mohr, B.1    Bhasin, S.2    Link, C.3    O'Donnell, A.4    McKinlay, J.5
  • 12
    • 33750177610 scopus 로고    scopus 로고
    • The association between obesity and the diagnosis of androgen deficiency in symptomatic ageing men
    • Allan CA., Strauss BJ., Burger HG., Forbes EA., McLachlan RI. The association between obesity and the diagnosis of androgen deficiency in symptomatic ageing men. Med J Aust 2006;185: 424-7.
    • (2006) Med J Aust , vol.185 , pp. 424-427
    • Allan, C.1    Strauss, B.2    Burger, H.3    Forbes, E.4    McLachlan, R.5
  • 13
    • 34247605052 scopus 로고    scopus 로고
    • Androgen deficiency, diabetes, and the metabolic syndrome in men
    • Kalyani RR., Dobs AS. Androgen deficiency., diabetes, and the metabolic syndrome in men. Curr Opin Endocrinol Diabetes Obes 2007;14:226-34.
    • (2007) Curr Opin Endocrinol Diabetes Obes , vol.14 , pp. 226-234
    • Kalyani, R.1    Dobs, A.2
  • 15
    • 0034106347 scopus 로고    scopus 로고
    • Testosterone, sex hormone-binding globulin, and the development of type 2 diabetes in middle-aged men: prospective results from the Massachusetts Male Aging Study
    • Stellato RK., Feldman HA., Hamdy O., Horton ES., McKinlay JB. Testosterone, sex hormone-binding globulin, and the development of type 2 diabetes in middle-aged men: prospective results from the Massachusetts Male Aging Study. Diabetes Care 2000;23:490-4.
    • (2000) Diabetes Care , vol.23 , pp. 490-494
    • Stellato, R.1    Feldman, H.2    Hamdy, O.3    Horton, E.4    McKinlay, J.5
  • 17
    • 33646029746 scopus 로고    scopus 로고
    • Insulin sensitivity during combined androgen blockade for prostate cancer
    • Smith MR., Lee H., Nathan DM. Insulin sensitivity during combined androgen blockade for prostate cancer. J Clin Endocrinol Metab 2006;91:1305-8.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 1305-1308
    • Smith, M.1    Lee, H.2    Nathan, D.3
  • 18
    • 31544440178 scopus 로고    scopus 로고
    • Hyper-glycemia and insulin resistance in men with prostate carcinoma who receive androgen-deprivation therapy
    • Basaria S., Muller DC., Carducci MA., Egan J., Dobs AS. Hyper-glycemia and insulin resistance in men with prostate carcinoma who receive androgen-deprivation therapy. Cancer 2006;106: 581-8.
    • (2006) Cancer , vol.106 , pp. 581-588
    • Basaria, S.1    Muller, D.2    Carducci, M.3    Egan, J.4    Dobs, A.5
  • 19
    • 35948930594 scopus 로고    scopus 로고
    • Acute sex steroid withdrawal reduces insulin sensitivity in healthy men with idiopathic hypogonadotropic hypogonadism
    • Yialamas MA., Dwyer AA., Hanley E., Lee H., Pitteloud N., Hayes FJ. Acute sex steroid withdrawal reduces insulin sensitivity in healthy men with idiopathic hypogonadotropic hypogonadism. J Clin Endocrinol Metab 2007;92:4254-9.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 4254-4259
    • Yialamas, M.1    Dwyer, A.2    Hanley, E.3    Lee, H.4    Pitteloud, N.5    Hayes, F.6
  • 20
    • 39849099669 scopus 로고    scopus 로고
    • Non-alcoholic fatty liver disease and the metabolic syndrome: an update
    • Rector RS., Thyfault JP., Wei Y., Ibdah JA. Non-alcoholic fatty liver disease and the metabolic syndrome: an update. World J Gastroenterol 2008;14:185-92.
    • (2008) World J Gastroenterol , vol.14 , pp. 185-192
    • Rector, R.1    Thyfault, J.2    Wei, Y.3    Ibdah, J.4
  • 21
    • 57349116780 scopus 로고    scopus 로고
    • Causes and metabolic consequences of fatty liver
    • Stefan N., Kantartzis K., Haring HU. Causes and metabolic consequences of fatty liver. Endocr Rev 2008;29:939-60.
    • (2008) Endocr Rev , vol.29 , pp. 939-960
    • Stefan, N.1    Kantartzis, K.2    Haring, H.3
  • 22
    • 44449129581 scopus 로고    scopus 로고
    • Should nonalcoholic fatty liver disease be included in the definition of metabolic syndrome? A cross-sectional comparison with Adult Treatment Panel III criteria in nonobese non-diabetic subjects
    • Musso G., Gambino R., Bo S., Uberti B., Biroli G., Pagano G., Cassader M. Should nonalcoholic fatty liver disease be included in the definition of metabolic syndrome? A cross-sectional comparison with Adult Treatment Panel III criteria in nonobese non-diabetic subjects. Diabetes Care 2008;31:562-8.
    • (2008) Diabetes Care , vol.31 , pp. 562-568
    • Musso, G.1    Gambino, R.2    Bo, S.3    Uberti, B.4    Biroli, G.5    Pagano, G.6    Cassader, M.7
  • 24
    • 11144237718 scopus 로고    scopus 로고
    • Association between elevated liver enzymes and C-reactive protein: possible hepatic contribution to systemic inflammation in the metabolic syndrome
    • Kerner A., Avizohar O., Sella R., Bartha P., Zinder O., Markiewicz W., Levy Y., Brook GJ., Aronson D. Association between elevated liver enzymes and C-reactive protein: possible hepatic contribution to systemic inflammation in the metabolic syndrome. Arterioscler Thromb Vasc Biol 2005;25:193-7.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 193-197
    • Kerner, A.1    Avizohar, O.2    Sella, R.3    Bartha, P.4    Zinder, O.5    Markiewicz, W.6    Levy, Y.7    Brook, G.8    Aronson, D.9
  • 25
    • 38149032364 scopus 로고    scopus 로고
    • Testosterone therapy prevents gain in visceral adipose tissue and loss of skeletal muscle in non-obese aging men
    • Allan CA., Strauss BJ., Burger HG., Forbes EA., McLachlan RI. Testosterone therapy prevents gain in visceral adipose tissue and loss of skeletal muscle in non-obese aging men. J Clin Endocrinol Metab 2008;93:139-46.
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 139-146
    • Allan, C.1    Strauss, B.2    Burger, H.3    Forbes, E.4    McLachlan, R.5
  • 29
    • 0035897696 scopus 로고    scopus 로고
    • Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
    • Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). J Am Med Assoc 2001;285: 2486-97.
    • (2001) J Am Med Assoc , vol.285 , pp. 2486-2497
  • 32
    • 38049169172 scopus 로고    scopus 로고
    • A dose-response study of testosterone on sexual dysfunction and features of the metabolic syndrome using testosterone gel and parenteral testosterone undecanoate
    • Saad F., Gooren LJ., Haider A., Yassin A. A dose-response study of testosterone on sexual dysfunction and features of the metabolic syndrome using testosterone gel and parenteral testosterone undecanoate. J Androl 2008;29:102-5.
    • (2008) J Androl , vol.29 , pp. 102-105
    • Saad, F.1    Gooren, L.2    Haider, A.3    Yassin, A.4
  • 33
    • 33644862944 scopus 로고    scopus 로고
    • Metabolic abnormalities identified by anthropometric measures in elderly men
    • (author reply 4)
    • Esmaillzadeh A., Mirmiran P., Azizi F. Metabolic abnormalities identified by anthropometric measures in elderly men. Am J Clin Nutr 2006;83:173-4 (author reply 4).
    • (2006) Am J Clin Nutr , vol.83 , pp. 173-174
    • Esmaillzadeh, A.1    Mirmiran, P.2    Azizi, F.3
  • 34
    • 38149032364 scopus 로고    scopus 로고
    • Testosterone therapy prevents gain in visceral adipose tissue and loss of skeletal muscle in nonobese aging men
    • Allan CA., Strauss BJ., Burger HG., Forbes EA., McLachlan RI. Testosterone therapy prevents gain in visceral adipose tissue and loss of skeletal muscle in nonobese aging men. J Clin Endocri-nol Metab 2008;93:139-46.
    • (2008) J Clin Endocri-nol Metab , vol.93 , pp. 139-146
    • Allan, C.1    Strauss, B.2    Burger, H.3    Forbes, E.4    McLachlan, R.5
  • 35
    • 0028797188 scopus 로고
    • Assimilation and mobilization of triglycerides in subcutaneous abdominal and femoral adipose tissue in vivo in men: effects of androgens
    • Marin P., Oden B., Bjorntorp P. Assimilation and mobilization of triglycerides in subcutaneous abdominal and femoral adipose tissue in vivo in men: effects of androgens. J Clin Endocrinol Metab 1995;80:239-43.
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 239-243
    • Marin, P.1    Oden, B.2    Bjorntorp, P.3
  • 36
    • 15944404290 scopus 로고    scopus 로고
    • Exogenous testosterone (T) alone or with finasteride increases physical performance, grip strength, and lean body mass in older men with low serum T
    • Page ST., Amory JK., Bowman FD., Anawalt BD., Matsumoto AM., Bremner WJ., Tenover JL. Exogenous testosterone (T) alone or with finasteride increases physical performance, grip strength, and lean body mass in older men with low serum T. J Clin Endocrinol Metab 2005;90:1502-10.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 1502-1510
    • Page, S.1    Amory, J.2    Bowman, F.3    Anawalt, B.4    Matsumoto, A.5    Bremner, W.6    Tenover, J.7
  • 37
    • 43749115158 scopus 로고    scopus 로고
    • An exploratory study of the effects of 12 month administration of the novel long-acting testosterone undecanoate on measures of sexual function and the metabolic syndrome
    • Saad F., Gooren L., Haider A., Yassin A. An exploratory study of the effects of 12 month administration of the novel long-acting testosterone undecanoate on measures of sexual function and the metabolic syndrome. Arch Androl 2007;53:353-7.
    • (2007) Arch Androl , vol.53 , pp. 353-357
    • Saad, F.1    Gooren, L.2    Haider, A.3    Yassin, A.4
  • 38
    • 43849108451 scopus 로고    scopus 로고
    • Erectile dysfunction, metabolic syndrome, hypogonadism are intertwined
    • Yassin AS., Saad F. Erectile dysfunction, metabolic syndrome, hypogonadism are intertwined. J Urol 2007;177:288.
    • (2007) J Urol , vol.177 , pp. 288
    • Yassin, A.1    Saad, F.2
  • 39
    • 38349016541 scopus 로고    scopus 로고
    • Effects of testosterone gel followed by parenteral testosterone undecanoate on sexual dysfunction and on features of the metabolic syndrome
    • Saad F., Gooren L., Haider A., Yassin A. Effects of testosterone gel followed by parenteral testosterone undecanoate on sexual dysfunction and on features of the metabolic syndrome. Andro-logia 2008;40:44-8.
    • Andro-logia , vol.40 , pp. 44-48
    • Saad, F.1    Gooren, L.2    Haider, A.3    Yassin, A.4
  • 40
    • 18844362098 scopus 로고    scopus 로고
    • Increasing insulin resistance is associated with a decrease in Leydig cell testosterone secretion in men
    • Pitteloud N., Hardin M., Dwyer AA., Valassi E., Yialamas M., Elahi D., Hayes FJ. Increasing insulin resistance is associated with a decrease in Leydig cell testosterone secretion in men. J Clin Endocrinol Metab 2005;90:2636-41.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 2636-2641
    • Pitteloud, N.1    Hardin, M.2    Dwyer, A.3    Valassi, E.4    Yialamas, M.5    Elahi, D.6    Hayes, F.7
  • 41
    • 48349144149 scopus 로고    scopus 로고
    • Testosterone treatment in elderly men with subnormal testosterone levels improves body composition and BMD in the hip
    • Svartberg J., Agledahl I., Figenschau Y., Sildnes T., Waterloo K., Jorde R. Testosterone treatment in elderly men with subnormal testosterone levels improves body composition and BMD in the hip. Int J Impot Res 2008;20:378-87.
    • (2008) Int J Impot Res , vol.20 , pp. 378-387
    • Svartberg, J.1    Agledahl, I.2    Figenschau, Y.3    Sildnes, T.4    Waterloo, K.5    Jorde, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.