메뉴 건너뛰기




Volumn 12, Issue 4, 2011, Pages 435-441

Pharmaceutical sponsorship bias influences thrombolytic literature in acute ischemic stroke

Author keywords

[No Author keywords available]

Indexed keywords


EID: 81255179874     PISSN: 1936900X     EISSN: 19369018     Source Type: Journal    
DOI: 10.5811/westjem.2011.5.2166     Document Type: Review
Times cited : (5)

References (51)
  • 3
    • 10744221456 scopus 로고    scopus 로고
    • European stroke initiative recommendations for stroke management: Update 2003
    • European Stroke Initiative Executive Committee and European Stroke Initiative Writing Group
    • The European Stroke Initiative Executive Committee and European Stroke Initiative Writing Group. European stroke initiative recommendations for stroke management: update 2003. Cerebrovasc Dis. 2003;16:311-337.
    • (2003) Cerebrovasc Dis. , vol.16 , pp. 311-337
  • 5
    • 32944456011 scopus 로고    scopus 로고
    • Emergency physician survey: Recombinant tissue plasminogen activator for stroke
    • Wals M, Fromm G. Emergency physician survey: recombinant tissue plasminogen activator for stroke. Ann Emerg Med. 2005;47:296-297.
    • (2005) Ann Emerg Med. , vol.47 , pp. 296-297
    • Wals, M.1    Fromm, G.2
  • 6
    • 34250348991 scopus 로고    scopus 로고
    • Position statement on the use of intravenous thrombolytic therapy in the treatment of stroke
    • Available at:, Accessed April 2011
    • Goyal DG, Li J, Mann J, et al. Position statement on the use of intravenous thrombolytic therapy in the treatment of stroke. American Academy of Emergency Medicine Web site. Available at: http://www.aaem.org/ positionstatements/thrombolytictherapy.php. Accessed April 2011.
    • American Academy of Emergency Medicine Web Site
    • Goyal, D.G.1    Li, J.2    Mann, J.3
  • 7
    • 84864580022 scopus 로고    scopus 로고
    • Use of intravenous tPa for the management of acute stroke in the emergency department
    • Available at:, Accessed April 2011
    • ACEP Board of Directors. Use of intravenous tPa for the management of acute stroke in the emergency department. American College of Emergency Physicians Web site. Available at: http://www.acep.org/practres.aspx?id=29834. Accessed April 2011.
    • American College of Emergency Physicians Web Site
  • 8
    • 0037160920 scopus 로고    scopus 로고
    • Alteplase for stroke: Money and optimistic claims buttress the brain attack campaign
    • Lenzer J. Alteplase for stroke: money and optimistic claims buttress the "brain attack" campaign. BMJ. 2002;324:723-726. (Pubitemid 34259150)
    • (2002) British Medical Journal , vol.324 , Issue.7339 , pp. 723-726
    • Lenzer, J.1
  • 9
    • 0003674363 scopus 로고    scopus 로고
    • American Heart Association, Dallas: AHA
    • American Heart Association. Annual Report 1999. Dallas: AHA, 2000.
    • (2000) Annual Report 1999
  • 10
    • 79955141261 scopus 로고    scopus 로고
    • Can we trust cardiovascular practice guidelines?
    • Nissen SE. Can we trust cardiovascular practice guidelines? Arch Intern Med. 2011;171:584-585.
    • (2011) Arch Intern Med. , vol.171 , pp. 584-585
    • Nissen, S.E.1
  • 11
    • 79955148848 scopus 로고    scopus 로고
    • Conflicts of interest in cardiovascular clinical practice guidelines
    • Mendelson TB, Meltzer M, Campbell EG, et al. Conflicts of interest in cardiovascular clinical practice guidelines. Arch Intern Med. 2011;171:577-584.
    • (2011) Arch Intern Med. , vol.171 , pp. 577-584
    • Mendelson, T.B.1    Meltzer, M.2    Campbell, E.G.3
  • 12
    • 0037460196 scopus 로고    scopus 로고
    • Scope and impact of financial conflicts of interest in biomedical research: A systematic review
    • Bekelman JE, Li Y, Gross CP. Scope and impact of financial conflicts of interest in biomedical research: a systematic review. JAMA. 2003;289:454-469.
    • (2003) JAMA , vol.289 , pp. 454-469
    • Bekelman, J.E.1    Li, Y.2    Gross, C.P.3
  • 13
    • 39049096171 scopus 로고    scopus 로고
    • Pharmaceutical company funding and its consequences: A qualitative systematic review
    • DOI 10.1016/j.cct.2007.08.001, PII S1551714407001255
    • Sismondo S. Pharmaceutical company funding and its consequences: a qualitative systematic review. Cont Clin Trials. 2007;29:109-113. (Pubitemid 351248768)
    • (2008) Contemporary Clinical Trials , vol.29 , Issue.2 , pp. 109-113
    • Sismondo, S.1
  • 14
    • 63449112089 scopus 로고    scopus 로고
    • New developments in the use of citation analysis in research evaluation
    • Moed HF. New developments in the use of citation analysis in research evaluation. Arch Immunol Ther Exp. (Warsz) 2009;57:13-18.
    • (2009) Arch Immunol Ther Exp. (Warsz) , vol.57 , pp. 13-18
    • Moed, H.F.1
  • 15
    • 59849096849 scopus 로고    scopus 로고
    • The use and misuse of journal metrics and other citation indicators
    • Pendlebury DA. The use and misuse of journal metrics and other citation indicators. Arch Immunol Ther Exp. (Warsz) 2009;57:1-11.
    • (2009) Arch Immunol Ther Exp. (Warsz) , vol.57 , pp. 1-11
    • Pendlebury, D.A.1
  • 16
    • 38949137710 scopus 로고    scopus 로고
    • Comparison of PubMed, Scopus, Web of Science, and Google Scholar: Strengths and weaknesses
    • DOI 10.1096/fj.07-9492LSF
    • Falagas ME, Pitsouni El, Malietzis R, et al. Comparison of PubMed, Scopus, Web of Science, and Google Scholar: strengths and weaknesses. FASEB J. 2008;22:338-342. (Pubitemid 351225599)
    • (2008) FASEB Journal , vol.22 , Issue.2 , pp. 338-342
    • Falagas, M.E.1    Pitsouni, E.I.2    Malietzis, G.A.3    Pappas, G.4
  • 17
    • 0028226514 scopus 로고
    • Prospective study of endogenous tissue plasminogen activator and risk of stroke
    • DOI 10.1016/S0140-6736(94)90064-7
    • Ridker PM, Hennekens CH, Stampfer MJ, et al. Prospective-study of endogenous-tissue plasminogen-activator and risk of stroke. Lancet. 1994;343:940-943. (Pubitemid 24117228)
    • (1994) Lancet , vol.343 , Issue.8903 , pp. 940-943
    • Ridker, P.M.1    Hennekens, C.H.2    Stampfer, M.J.3    Manson, J.E.4    Vaughan, D.E.5
  • 18
    • 81255209773 scopus 로고    scopus 로고
    • Acute stroke: Usefulness of early CT findings before thrombolytic therapy
    • Von Kummer R, Alle KL, Holle R, et al. Acute stroke: usefulness of early CT findings before thrombolytic therapy. Radiology. 1999;205:315-318.
    • (1999) Radiology , vol.205 , pp. 315-318
    • Von Kummer, R.1    Alle, K.L.2    Holle, R.3
  • 19
    • 84864593233 scopus 로고    scopus 로고
    • Fact sheet
    • Available at:, Accessed April 2011
    • Burroughs-Wellcome Fund. Fact sheet. Burroughs-Wellcome Fund Web site. Available at: http://www.bwfund.org/pages/58/Fact-Sheet. Accessed April 2011.
    • Burroughs-wellcome Fund Web Site
  • 20
    • 77956301619 scopus 로고    scopus 로고
    • Relationship between sponsorship and failure rate of dental implants: A systematic approach
    • Popelut A, Valet F, Fromentin O, et al. Relationship between sponsorship and failure rate of dental implants: a systematic approach. PLoS ONE. 2010;5:e10274.
    • (2010) PLoS ONE. , vol.5
    • Popelut, A.1    Valet, F.2    Fromentin, O.3
  • 21
    • 56549110284 scopus 로고    scopus 로고
    • Is there evidence for biased report of published adverse effects data in pharmaceutical industry-funded studies?
    • Golder S, Loke Y. Is there evidence for biased report of published adverse effects data in pharmaceutical industry-funded studies? Br J Clin Pharmacol. 2008;66:767-773.
    • (2008) Br J Clin Pharmacol. , vol.66 , pp. 767-773
    • Golder, S.1    Loke, Y.2
  • 22
    • 77952787734 scopus 로고    scopus 로고
    • Reporting and interpretation of randomized controlled trials with statistically nonsignificant results for primary outcomes
    • Boutron I, Dutton S, Ravaud P, et al. Reporting and interpretation of randomized controlled trials with statistically nonsignificant results for primary outcomes. JAMA. 2010;303:2058-2064.
    • (2010) JAMA , vol.303 , pp. 2058-2064
    • Boutron, I.1    Dutton, S.2    Ravaud, P.3
  • 23
    • 42249091217 scopus 로고    scopus 로고
    • Impugning the integrity of medical science: The adverse effects of industry influence
    • DeAngelis CD, Fontanarosa PB. Impugning the integrity of medical science: the adverse effects of industry influence. JAMA. 2008;299:1800-1812.
    • (2008) JAMA , vol.299 , pp. 1800-1812
    • DeAngelis, C.D.1    Fontanarosa, P.B.2
  • 24
    • 0037160932 scopus 로고    scopus 로고
    • Commentary: Thrombolysis in stroke it works!
    • Saver J, Kidwell C, Starkman S. Commentary: thrombolysis in stroke it works! BMJ. 2002;324:727-729.
    • (2002) BMJ. , vol.324 , pp. 727-729
    • Saver, J.1    Kidwell, C.2    Starkman, S.3
  • 25
    • 77949298688 scopus 로고    scopus 로고
    • Whether industry-supported or otherwise, trust is key to the acceptance of all research
    • Glick M. Whether industry-supported or otherwise, trust is key to the acceptance of all research. JADA. 2010;141:127-128.
    • (2010) JADA. , vol.141 , pp. 127-128
    • Glick, M.1
  • 26
    • 68749100878 scopus 로고    scopus 로고
    • Expansion of the time window for treatment of acute ischemic stroke with intravenous tissue plasminogen activator: A science advisory from the American heart association/american stroke association
    • Del Zoppo GJ, Saver J, Jauch EC, et al. Expansion of the time window for treatment of acute ischemic stroke with intravenous tissue plasminogen activator: a science advisory from the American Heart Association/American Stroke Association. Stroke. 2009;40:2945-2948.
    • (2009) Stroke , vol.40 , pp. 2945-2948
    • Del Zoppo, G.J.1    Saver, J.2    Jauch, E.C.3
  • 27
    • 68649084182 scopus 로고    scopus 로고
    • A graphical re-analysis of the NINDS trial
    • Hoffman J, Schriger DL. A graphical re-analysis of the NINDS Trial. Ann Emerg Med. 2009;54:329-336.
    • (2009) Ann Emerg Med. , vol.54 , pp. 329-336
    • Hoffman, J.1    Schriger, D.L.2
  • 28
    • 71849095831 scopus 로고    scopus 로고
    • Stroke treatment with alteplase given 3.0-4.5 h after onset of acute ischaemic stroke (ECASS III): Additional outcomes and subgroup analysis of a randomized controlled trial
    • Bluhmki E, Chamorro A, Davalos A, et al. Stroke treatment with alteplase given 3.0-4.5 h after onset of acute ischaemic stroke (ECASS III): additional outcomes and subgroup analysis of a randomized controlled trial. Lancet Neurol. 2009;8:1095-1102.
    • (2009) Lancet Neurol. , vol.8 , pp. 1095-1102
    • Bluhmki, E.1    Chamorro, A.2    Davalos, A.3
  • 29
    • 77958017744 scopus 로고    scopus 로고
    • Is thrombolysis safe in the elderly? Analysis of a national database
    • Alshekhlee A, Mohammadi A, Mehta S. Is thrombolysis safe in the elderly? Analysis of a national database. Stroke. 2010;41:2259-2264.
    • (2010) Stroke. , vol.41 , pp. 2259-2264
    • Alshekhlee, A.1    Mohammadi, A.2    Mehta, S.3
  • 30
    • 84864580024 scopus 로고    scopus 로고
    • Third international stroke trial (IST-3)
    • Available at:, Accessed March 2011
    • Sandercock PA, Wardlaw J, Lindley R. Third International Stroke Trial (IST-3). Internet Stroke Center Web site. Available at: http://www.strokecenter. org/trials/TrialDetail.aspx?tid=81. Accessed March 2011.
    • Internet Stroke Center Web Site
    • Sandercock, P.A.1    Wardlaw, J.2    Lindley, R.3
  • 31
    • 33745964452 scopus 로고    scopus 로고
    • Thrombolysis (tissue plasminogen activator) in stroke: A medicolegal quagmire
    • DOI 10.1161/01.STR.0000226651.04862.da, PII 0000767020060700000067
    • Weintraub M. Thrombolysis (tissue plasminogen activator) in stroke: a medicolegal quagmire. Stroke. 2006;37:1917-1922. (Pubitemid 44297752)
    • (2006) Stroke , vol.37 , Issue.7 , pp. 1917-1922
    • Weintraub, M.I.1
  • 32
    • 0028783948 scopus 로고
    • Tissue plasminogen activator for acute ischemic stroke. The national institute of neurological disorders and stroke rt-PA stroke study group
    • No authors listed
    • [No authors listed]. Tissue plasminogen activator for acute ischemic stroke. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. N Engl J Med. 1995;333:1581-1587.
    • (1995) N Engl J Med. , vol.333 , pp. 1581-1587
  • 33
    • 0029050323 scopus 로고
    • Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke. The European cooperative acute stroke study (ECASS)
    • Hacke W, Kaste M, Fieschi C, et al. Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke. The European Cooperative Acute Stroke Study (ECASS). JAMA. 1995;274:1017-1025.
    • (1995) JAMA , vol.274 , pp. 1017-1025
    • Hacke, W.1    Kaste, M.2    Fieschi, C.3
  • 34
    • 0033486107 scopus 로고    scopus 로고
    • Intra-arterial prourokinase for acute ischemic stroke. The PROACT II study: A randomized controlled trial. Prolyse in acute cerebral thromboembolism
    • Furlan A, Higashida R, Wechsler L, et al. Intra-arterial prourokinase for acute ischemic stroke. The PROACT II study: a randomized controlled trial. Prolyse in Acute Cerebral Thromboembolism. JAMA. 1999;282:2003-2011.
    • (1999) JAMA , vol.282 , pp. 2003-2011
    • Furlan, A.1    Higashida, R.2    Wechsler, L.3
  • 36
    • 1542315556 scopus 로고    scopus 로고
    • Association of outcome with early stroke treatment: Pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials
    • Hacke W, Donnan G, Fieschi C, et al. Association of outcome with early stroke treatment: pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials. Lancet. 2004;363:768-774.
    • (2004) Lancet. , vol.363 , pp. 768-774
    • Hacke, W.1    Donnan, G.2    Fieschi, C.3
  • 37
    • 0033485522 scopus 로고    scopus 로고
    • Recombinant tissue-type plasminogen activator (Alteplase) for ischemic stroke 3 to 5 hours after symptom onset. The ATLANTIS study: A randomized controlled trial. Alteplase thrombolysis for acute noninterventional therapy in ischemic stroke
    • Clark WM, Wissman S, Albers GW, et al. Recombinant tissue-type plasminogen activator (Alteplase) for ischemic stroke 3 to 5 hours after symptom onset. The ATLANTIS Study: a randomized controlled trial. Alteplase Thrombolysis for Acute Noninterventional Therapy in Ischemic Stroke. JAMA. 1999;282:2019-2026.
    • (1999) JAMA , vol.282 , pp. 2019-2026
    • Clark, W.M.1    Wissman, S.2    Albers, G.W.3
  • 38
    • 0026759412 scopus 로고
    • Recombinant tissue plasminogen activator in acute thrombotic and embolic stroke
    • Del Zoppo GJ, Poeck K, Pessin MS, et al. Recombinant tissue plasminogen activator in acute thrombotic and embolic stroke. Ann Neurol. 1992;32:78-86.
    • (1992) Ann Neurol. , vol.32 , pp. 78-86
    • Del Zoppo, G.J.1    Poeck, K.2    Pessin, M.S.3
  • 39
    • 52649165720 scopus 로고    scopus 로고
    • Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke
    • Hacke W, Kaste M, Bluhmki E, et al. Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke. N Engl J Med. 2008;359:1317-1329.
    • (2008) N Engl J Med. , vol.359 , pp. 1317-1329
    • Hacke, W.1    Kaste, M.2    Bluhmki, E.3
  • 41
    • 0028847213 scopus 로고
    • Randomised controlled trial of streptokinase, aspirin, and combination of both in treatment of acute ischemic stroke. Multicentre acute stroke trial-Italy (MAST-I) group
    • Candelise L, Aritzu E, Ciccone A, et al. Randomised controlled trial of streptokinase, aspirin, and combination of both in treatment of acute ischemic stroke. Multicentre Acute Stroke Trial-Italy (MAST-I) Group. Lancet. 1995;346:1509-1514.
    • (1995) Lancet. , vol.346 , pp. 1509-1514
    • Candelise, L.1    Aritzu, E.2    Ciccone, A.3
  • 43
    • 0034161354 scopus 로고    scopus 로고
    • Intravenous tissue-type plasminogen activator for treatment of acute stroke: The standard treatment with alteplase to reverse stroke (STARS) study
    • Albers GW, Bates VE, Clark WM, et al. Intravenous tissue-type plasminogen activator for treatment of acute stroke: the Standard Treatment with Alteplase to Reverse Stroke (STARS) study. JAMA. 2000;283:1145-1150. (Pubitemid 30126602)
    • (2000) Journal of the American Medical Association , vol.283 , Issue.9 , pp. 1145-1150
    • Albers, G.W.1    Bates, V.E.2    Clark, W.M.3    Bell, R.4    Verro, P.5    Hamilton, S.A.6
  • 44
    • 8644230974 scopus 로고    scopus 로고
    • Ultrasound-enhanced systemic thrombolysis for acute ischemic stroke
    • Alexandrov AV, Molina CA, Grotta JC, et al. Ultrasound-enhanced systemic thrombolysis for acute ischemic stroke. N Engl J Med. 2004;351:2170-2180.
    • (2004) N Engl J Med. , vol.351 , pp. 2170-2180
    • Alexandrov, A.V.1    Molina, C.A.2    Grotta, J.C.3
  • 45
    • 0034642165 scopus 로고    scopus 로고
    • Early stroke treatment associated with better outcome: The NINDS rt-PA stroke study
    • Marler JR, Tilley BC, Lu M, et al. Early stroke treatment associated with better outcome: the NINDS rt-PA stroke study. Neurology. 2000;55:1649-1655.
    • (2000) Neurology , vol.55 , pp. 1649-1655
    • Marler, J.R.1    Tilley, B.C.2    Lu, M.3
  • 46
    • 0026742376 scopus 로고
    • Urgent therapy for stroke. Part I. Pilot-study of tissue plasminogen activator administered within 90 minutes
    • Brott TG, Haley EC Jr, Levy DE, et al. Urgent therapy for stroke. Part I. Pilot-study of tissue plasminogen activator administered within 90 minutes. Stroke. 1992;23:632-640.
    • (1992) Stroke. , vol.23 , pp. 632-640
    • Brott, T.G.1    Haley Jr., E.C.2    Levy, D.E.3
  • 48
    • 0000945065 scopus 로고    scopus 로고
    • Thrombolytic therapy with streptokinase in acute ischemic stroke
    • DOI 10.1056/NEJM199607183350301
    • Hommel M, Cornu C, Boutitie F, et al. Thrombolytic therapy with streptokinase in acute ischemic stroke. The Multicenter Acute Stroke Trial-Europe Study Group. N Engl J Med. 1996;335:145-150. (Pubitemid 26249450)
    • (1996) New England Journal of Medicine , vol.335 , Issue.3 , pp. 145-150
    • Hommel, M.1    Cornu, C.2    Boutitie, F.3    Boissel, J.P.4
  • 49
    • 0026736173 scopus 로고
    • Intravenous recombinant tissue plasminogen-activator in acute carotid-artery territory stroke
    • Mori E, Yoneda Y, Tabuchi M, et al. Intravenous recombinant tissue plasminogen-activator in acute carotid-artery territory stroke. Neurology. 1992;42:976-982.
    • (1992) Neurology , vol.42 , pp. 976-982
    • Mori, E.1    Yoneda, Y.2    Tabuchi, M.3
  • 50
    • 0032710461 scopus 로고    scopus 로고
    • Combined intravenous and intra-arterial r-TPA versus intra-arterial therapy of acute ischemic stroke: Emergency management of stroke (EMS) bridging trial
    • Lewandowski CA, Frankel M, Tomsick TA, et al. Combined intravenous and intra-arterial r-TPA versus intra-arterial therapy of acute ischemic stroke: Emergency Management of Stroke (EMS) Bridging Trial. Stroke. 1999;30:2598-2605.
    • (1999) Stroke. , vol.30 , pp. 2598-2605
    • Lewandowski, C.A.1    Frankel, M.2    Tomsick, T.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.