A novel strategy to develop therapeutic approaches to prevent Proliferative vitreoretinopathy

American Journal of Pathology

Volumn 179, Issue 6, 2011, Pages 2931-2940

  Pennock, Steven ^a,b,c   Rheaume, Marc Andre ^b,c   Mukai, Shizuo ^b,c   Kazlauskas, Andrius ^a,b  

^a SCHEPENS EYE RESEARCH INSTITUTE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c MASSACHUSETTS EYE AND EAR INFIRMARY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONNECTIVE TISSUE GROWTH FACTOR; CYTOKINE; EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 2; GAMMA INTERFERON; GRANULOCYTE COLONY STIMULATING FACTOR; GROWTH FACTOR; IMMUNOGLOBULIN G; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MONOCYTE CHEMOTACTIC PROTEIN 1; NEUTRALIZING ANTIBODY; NEUTRALIZING REAGENT SOLUTION RNB; PLATELET DERIVED GROWTH FACTOR A; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PLATELET DERIVED GROWTH FACTOR C; PROTEIN KINASE B; PROTEIN P53; SCATTER FACTOR; SOMATOMEDIN C; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; TUMOR NECROSIS FACTOR RECEPTOR; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN A;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVITY; CONTROLLED STUDY; DRUG TARGETING; EMBRYO; ENZYME ACTIVATION; EPIRETINAL MEMBRANE; EXPERIMENTAL RABBIT; EYE PROTECTION; FEMALE; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; SIGNAL TRANSDUCTION; VITRECTOMY; VITREORETINOPATHY; VITREOUS BODY; WESTERN BLOTTING;

ANIMALS; CELLS, CULTURED; CYTOKINES; FEMALE; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; RABBITS; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA; RECOMBINANT PROTEINS; RETINAL DETACHMENT; SIGNAL TRANSDUCTION; VITREORETINOPATHY, PROLIFERATIVE; VITREOUS BODY;

EID: 81255157506     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2011.08.043     Document Type: Article

References (50)

1. D. Han Proliferative vitreoretinopathy D. Albert, M. JW, A. DT, B. BA, 2008 Elsevier Saunders Philadelphia, PA 2315 2324
2. J.C. Pastor Proliferative vitreoretinopathy: an overview Surv Ophthalmol 43 1998 3 18 (Pubitemid 28364465)
3. R.G. Michels, C.P. Wilkinson, and A. Rice Proliferative retinopathy 1990 Mosby St. Louis, MO
4. B.M. Glaser, A. Cardin, and B. Biscoe Proliferative vitreoretinopathy The mechanism of development of vitreoretinal traction Ophthalmology 94 1987 327 332 (Pubitemid 17056017)
5. P.A. Campochiaro Mechanisms in ophthalmic disease: pathogenic mechanisms in proliferative vitreoretinopathy Arch Ophthalmol 115 1997 237 241 (Pubitemid 27083797)
6. H. Laqua, and R. achemer Glial cell proliferation in retinal detachment (massive periretinal proliferation) Am J Ophthalmol 80 1975 602 618
7. S.J. Ryan Traction retinal detachment XLIX Edward Jackson Memorial Lecture Am J Ophthalmol 115 1993 1 20 (Pubitemid 23019032)
8. S. Banerjee, V. Savant, R.A. Scott, S.J. Curnow, G.R. Wallace, and P.I. Murray Multiplex bead analysis of vitreous humor of patients with vitreoretinal disorders Invest Ophthalmol Vis Sci 48 2007 2203 2207 (Pubitemid 351261295)
9. R.H. Asaria, C.H. Kon, C. Bunce, C.S. Sethi, G.A. Limb, P.T. Khaw, G.W. Aylward, and D.G. Charteris Silicone oil concentrates fibrogenic growth factors in the retro-oil fluid Br J Ophthalmol 88 2004 1439 1442 (Pubitemid 39424727)
10. C. Baudouin, D. Fredj-Reygrobellet, F. Brignole, F. Negre, P. Lapalus, and P. Gastaud Growth factors in vitreous and subretinal fluid cells from patients with proliferative vitreoretinopathy Ophthalmic Res 25 1993 52 59 (Pubitemid 23078549)
11. P.A. Campochiaro, S.F. Hackett, and S.A. Vinores Growth factors in the retina and retinal pigmented epithelium Prog Ret Eye Res 15 1996 547 567 (Pubitemid 26329184)
12. H. Canataroglu, I. Varinli, A.A. Ozcan, A. Canataroglu, F. Doran, and S. Varinli Interleukin (IL)-6, interleukin (IL)-8 levels and cellular composition of the vitreous humor in proliferative diabetic retinopathy, proliferative vitreoretinopathy, and traumatic proliferative vitreoretinopathy Ocul Immunol Inflamm 13 2005 375 381 (Pubitemid 41702761)
13. C. Harada, Y. Mitamura, and T. Harada The role of cytokines and trophic factors in epiretinal membranes: involvement of signal transduction in glial cells Prog Retin Eye Res 25 2006 149 164 (Pubitemid 43227842)
14. E.C. La Heij, M.P. van de Waarenburg, H.G. Blaauwgeers, A.G. Kessels, A.T. Liem, C. Theunissen, H. Steinbusch, and F. Hendrikse Basic fibroblast growth factor, glutamine synthetase, and interleukin-6 in vitreous fluid from eyes with retinal detachment complicated by proliferative vitreoretinopathy Am J Ophthalmol 134 2002 367 375
15. I.A. El-Ghrably, H.S. Dua, G.M. Orr, D. Fischer, and P.J. Tighe Intravitreal invading cells contribute to vitreal cytokine milieu in proliferative vitreoretinopathy Br J Ophthalmol 85 2001 461 470 (Pubitemid 32275629)
16. P. Choudhury, W. Chen, and R.C. Hunt Production of platelet-derived growth factor by interleukin-1 beta and transforming growth factor-beta- stimulated retinal pigment epithelial cells leads to contraction of collagen gels Invest Ophthalmol Vis Sci 38 1997 824 833 (Pubitemid 27193507)
17. G.I. Liou, V.A. Pakalnis, S. Matragoon, S. Samuel, M.A. Behzadian, J. Baker, I.E. Khalil, P. Roon, R.B. Caldwell, R.C. Hunt, and D.M. Marcus HGF regulation of RPE proliferation in an IL-1beta/retinal hole-induced rabbit model of PVR Mol Vis 8 2002 494 501 (Pubitemid 36153643)
18. S.G. Elner, V.M. Elner, G.J. Jaffe, A. Stuart, S.L. Kunkel, and R.M. Strieter Cytokines in proliferative diabetic retinopathy and proliferative vitreoretinopathy Curr Eye Res 14 1995 1045 1053
19. D.G. Charteris Growth factors in proliferative vitreoretinopathy Br J Ophthalmol 82 1998 106 (Pubitemid 28176981)
20. S.C. Dieudonne, E.C. La Heij, R. Diederen, A.G. Kessels, A.T. Liem, A. Kijlstra, and F. Hendrikse High TGF-beta2 levels during primary retinal detachment may protect against proliferative vitreoretinopathy Invest Ophthalmol Vis Sci 45 2004 4113 4118 (Pubitemid 39411168)
21. Y. Oshima, T. Sakamoto, T. Hisatomi, C. Tsutsumi, H. Ueno, and T. Ishibashi Gene transfer of soluble TGF-beta type II receptor inhibits experimental proliferative vitreoretinopathy Gene Ther 9 2002 1214 1220
22. D.R. Hinton, S. He, M.L. Jin, E. Barron, and S.J. Ryan Novel growth factors involved in the pathogenesis of proliferative vitreoretinopathy Eye (Lond) 16 2002 422 428 (Pubitemid 34845970)
23. K. Lashkari, N. Rahimi, and A. Kazlauskas Hepatocyte growth factor receptor in human RPE cells: implications in proliferative vitreoretinopathy Invest Ophthalmol Vis Sci 40 1999 149 156 (Pubitemid 29029583)
24. S. Mukherjee, and C. Guidry The insulin-like growth factor system modulates retinal pigment epithelial cell tractional force generation Invest Ophthalmol Vis Sci 48 2007 1892 1899 (Pubitemid 351261379)
25. T. Kita, Y. Hata, M. Miura, S. Kawahara, S. Nakao, and T. Ishibashi Functional characteristics of connective tissue growth factor on vitreoretinal cells Diabetes 56 2007 1421 1428 (Pubitemid 46715616)
26. H. Lei, P. Hovland, G. Velez, A. Haran, D. Gilbertson, T. Hirose, and A. Kazlauskas A potential role for PDGF-C in experimental and clinical proliferative vitreoretinopathy Invest Ophthalmol Vis Sci 48 2007 2335 2342 (Pubitemid 351261314)
27. J.Z. Cui, A. Chiu, D. Maberley, P. Ma, A. Samad, and J.A. Matsubara Stage specificity of novel growth factor expression during development of proliferative vitreoretinopathy Eye (Lond) 21 2007 200 208 (Pubitemid 46454598)
28. C.H. Kon, N.L. Occleston, G.W. Aylward, and P.T. Khaw Expression of vitreous cytokines in proliferative vitreoretinopathy: a prospective study Invest Ophthalmol Vis Sci 40 1999 705 712 (Pubitemid 29109449)
29. R.N. Agrawal, S. He, C. Spee, J.Z. Cui, S.J. Ryan, and D.R. Hinton In vivo models of proliferative vitreoretinopathy Nat Protoc 2 2007 67 77 (Pubitemid 47040070)
30. A. Andrews, E. Balciunaite, F.L. Leong, M. Tallquist, P. Soriano, M. Refojo, and A. Kazlauskas Platelet-derived growth factor plays a key role in proliferative vitreoretinopathy Invest Ophthalmol Vis Sci 40 1999 2683 2689 (Pubitemid 29455500)
31. J. Cui, H. Lei, A. Samad, S. Basavanthappa, D. Maberley, J. Matsubara, and A. Kazlauskas PDGF receptors are activated in human epiretinal membranes Exp Eye Res 88 2009 438 444
32. Y. Ikuno, F.L. Leong, and A. Kazlauskas Attenuation of experimental proliferative vitreoretinopathy by inhibiting the platelet-derived growth factor receptor Invest Ophthalmol Vis Sci 41 2000 3107 3116
33. C.A. Wong, M.J. Potter, J.Z. Cui, T.S. Chang, P. Ma, A.L. Maberley, W.H. Ross, V.A. White, A. Samad, W. Jia, D. Hornan, and J.A. Matsubara Induction of proliferative vitreoretinopathy by a unique line of human retinal pigment epithelial cells Can J Ophthalmol 37 2002 211 220 (Pubitemid 34847244)
34. H. Lei, G. Velez, P. Hovland, T. Hirose, D. Gilbertson, and A. Kazlauskas Growth factors outside the PDGF family drive experimental PVR Invest Ophthalmol Vis Sci 50 2009 3394 3403
35. H. Lei, and A. Kazlauskas Growth factors outside of the platelet-derived growth factor (PDGF) family employ reactive oxygen species/Src family kinases to activate PDGF receptor alpha and thereby promote proliferation and survival of cells J Biol Chem 284 2009 6329 6336
36. H. Lei, G. Velez, and A. Kazlauskas Pathological signaling via platelet-derived growth factor {alpha} involves chronic activation of Akt and suppression of p53 Mol Cell Biol 31 2011 1788 1799
37. S.G. Robbins, R.N. Mixon, D.J. Wilson, C.E. Hart, J.E. Robertson, I. Westra, S.R. Planck, and J.T. Rosenbaum Platelet-derived growth factor ligands and receptors immunolocalized in proliferative retinal diseases Invest Ophthalmol Vis Sci 35 1994 3649 3663 (Pubitemid 24337978)
38. M. Nakagawa, M.F. Refojo, J.F. Marin, M. Doi, and F.I. Tolentino Retinoic acid in silicone and silicone-fluorosilicone copolymer oils in a rabbit model of proliferative vitreoretinopathy Invest Ophthalmol Vis Sci 36 1995 2388 2395
39. F. Grinnell, C.H. Ho, Y.C. Lin, and G. Skuta Differences in the regulation of fibroblast contraction of floating versus stressed collagen matrices J Biol Chem 274 1999 918 923
40. Y. Ikuno, and A. Kazlauskas TGFbeta1-dependent contraction of fibroblasts is mediated by the PDGFalpha receptor Invest Ophthalmol Vis Sci 43 2002 41 46 (Pubitemid 34032438)
41. D.M. Fastenberg, K.R. Diddie, N. Sorgente, and S.J. Ryan A comparison of different cellular inocula in an experimental model of massive periretinal proliferation Am J Ophthalmol 93 1982 559 564 (Pubitemid 12107404)
42. D. Maberley, J.Z. Cui, and J.A. Matsubara Vitreous leptin levels in retinal disease Eye (Lond) 20 2006 801 804 (Pubitemid 44316988)
43. H. Lei, M.A. Rheaume, and A. Kazlauskas Recent developments in our understanding of how platelet-derived growth factor (PDGF) and its receptors contribute to proliferative vitreoretinopathy Exp Eye Res 90 2010 376 381
44. H. Lei, G. Velez, J. Cui, A. Samad, D. Maberley, J. Matsubara, and A. Kazlauskas N-acetylcysteine suppresses retinal detachment in an experimental model of proliferative vitreoretinopathy Am J Pathol 177 2010 132 140
45. G.R. Grotendorst, H. Okochi, and N. Hayashi A novel transforming growth factor beta response element controls the expression of the connective tissue growth factor gene Cell Growth Differ 7 1996 469 480 (Pubitemid 26362091)
46. A. Igarashi, H. Okochi, D.M. Bradham, and G.R. Grotendorst Regulation of connective tissue growth factor gene expression in human skin fibroblasts and during wound repair Mol Biol Cell 4 1993 637 645 (Pubitemid 23183611)
47. L.P. Aiello, E.A. Pierce, E.D. Foley, H. Takagi, H. Chen, L. Riddle, N. Ferrara, G.L. King, and L.E. Smith Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins Proc Natl Acad Sci U S A 92 1995 10457 10461
48. I.G. Lee, S.L. Chae, and J.C. Kim Involvement of circulating endothelial progenitor cells and vasculogenic factors in the pathogenesis of diabetic retinopathy Eye 20 2006 546 552 (Pubitemid 43674990)
49. D. Watanabe, K. Suzuma, S. Matsui, M. Kurimoto, J. Kiryu, M. Kita, I. Suzuma, H. Ohashi, T. Ojima, T. Murakami, T. Kobayashi, S. Masuda, M. Nagao, N. Yoshimura, and H. Takagi Erythropoietin as a retinal angiogenic factor in proliferative diabetic retinopathy N Engl J Med 353 2005 782 792 (Pubitemid 41215487)
50. J.F. Arevalo, J.G. Sanchez, A.F. Lasave, L. Wu, M. Maia, S. Bonafonte, M. Brito, A.A. Alezzandrini, N. Restrepo, M.H. Berrocal, M. Saravia, M.E. Farah, J. Fromow-Guerra, and V. Morales-Canton Intravitreal bevacizumab (Avastin®) for diabetic retinopathy at 24-months: the 2008 Juan Verdaguer-Planas Lecture Curr Diabetes Rev 6 2010 313 322