Synthesis and evaluation of a bifunctional chelate for development of Bi(III)-labeled radioimmunoconjugates

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 24, 2011, Pages 7513-7515

  Dadwal, Mamta ^a   Kang, Chi Soo ^a   Song, Hyun A ^a   Sun, Xiang ^a   Dai, Anzhi ^a   Baidoo, Kwamena E ^b   Brechbiel, Martin W ^b   Chong, Hyun Soon ^a  

^a Illinois Institute of Technology   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

212Bi; 213Bi; Bifunctional ligand; Radioimmunotherapy; Trastuzumab

Indexed keywords

1,4,7,10 TETRAAZACYCLODODECANE 1,4,7,10 TETRAACETIC ACID; 7 [2 (BISCARBOXYMETHYLAMINO)ETHYL] 4,10 BIS CARBOXYMETHYL 1,4,7,10 TETRAAZACYCLODODEC 1 YL ACETIC ACID; BISMUTH 212; BISMUTH 213; CHELATING AGENT; PENTETIC ACID; TRASTUZUMAB; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; COMPLEX FORMATION; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOTOPE LABELING; PROTON NUCLEAR MAGNETIC RESONANCE; RADIOACTIVITY; STEREOCHEMISTRY; SUBSTITUTION REACTION;

ANTIBODIES, MONOCLONAL, HUMANIZED; BISMUTH; DRUG EVALUATION, PRECLINICAL; DRUG STABILITY; GLYCINE; HETEROCYCLIC COMPOUNDS, 1-RING; HUMANS; IMMUNOCONJUGATES; ISOTOPE LABELING; KINETICS; NEOPLASMS;

EID: 81255154480     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.06.107     Document Type: Article

References (17)

1. S. Hassfjell, and M.W. Brechbiel Chem. Rev. 101 2001 2019
2. S.J. Knox, and R.F. Meredith Semin. Radiat. Oncol. 10 2000 73
3. J.G. Jurcic, S.M. Larson, G. Sgouros, M.R. McDevitt, R.D. Finn, C.R. Divgi, A.M. Ballangrud, K.A. Klaus, D. Ma, J.L. Humm, M.W. Brechbiel, R. Molinet, and D.A. Scheinberg Blood 100 2002 1233
4. D.E. Milenic, K. Garmestani, E.D. Brady, P.D. Albert, A. Abdulla, J. Flynn, and M.W. Brechbiel Clin. Cancer Res. 13 2007 1926
5. D.A. Mulford, N. Pandit-Taskar, M.R. McDevitt, R.D. Finn, M.A. Weiss, C. Apostolidis, A. Morgenstern, C.R. Divgi, S.M. Larson, D.A. Scheinberg, and J.G. Jurcic Blood 104 2004 496a
6. B.J. Allen, C. Raja, S. Rizvi, Y. Li, W. Tsui, P. Graham, J.F. Thompson, R.A. Reisfeld, J. Kearsley, A. Morgenstern, and C. Apostolidis Cancer Biol. Ther. 4 2005 1318
7. S. Kneifel, D. Cordier, S. Good, M.C. Ionescu, A. Ghaffari, S. Hofer, M. Kretzschmar, M. Tolnay, C. Apostolidis, B. Waser, M. Arnold, J. Mueller-Brand, H.R. Maecke, J.C. Reubi, and A. Merlo Clin. Cancer Res. 12 2006 3843
8. C. Friesen, G. Glatting, B. Koop, K. Schwarz, A. Morgenstern, C. Apostolidis, K.M. Debatin, and S.N. Reske Cancer Res. 67 2007 1950
9. M.W. Brechbiel, and O.A. Gansow J. Chem. Soc. Perkin Trans. 1 1992 1173
10. T.N. Nikula, M.R. McDevitt, R.D. Finn, C. Wu, R.W. Kozak, K. Garmestani, M.W. Brechbiel, M.J. Curcio, C.G. Pippin, L. Tiffany-Jones, M.W. Geerlings Sr., C. Apostolidis, R. Molinet, O.A. Gansow, and D.A. Scheinberg J. Nucl. Med. 40 1999 166
11. D.E. Milenic, M. Roselli, S. Mirzadeh, C.G. Pippin, O.A. Gansow, D. Colcher, M.W. Brechbiel, and J. Schlom Cancer Biother. Radiopharm. 16 2001 133
12. H.S. Chong, S. Lim, K.E. Baidoo, D.E. Milenic, X. Ma, F. Jia, H.A. Song, M.W. Brechbiel, and M.R. Lewis Bioorg. Med. Chem. Lett. 18 2008 5792
13. M. Woods, G.E. Kiefer, S. Bott, A. Castillo-Muzquiz, C. Eshelbrenner, L. Michaudet, K. McMillan, S.D.K. Mudigunda, D. Ogrin, G. Tircso, S. Zhang, P. Zhao, and A.D. Sherry J. Am. Chem. Soc. 126 2004 9248
14. J. Baselga Ann. Oncol. 12 2001 S49
15. D.B. Agus, P.A. Bunn Jr., W. Franklin, M. Garcia, and R.F. Ozols Semin. Oncol. 27 2000 53
16. H.A. Song, C. Kang, K.E. Baidoo, D.E. Milenic, Y. Chen, A. Dai, M.W. Brechbiel, and H.S. Chong Bioconjugate Chem. 22 2011 1128
17. E. Dadachova, L.L. Chappell, and M.W. Brechbiel Nucl. Med. Biol. 26 1999 977