Peptide-directed HPMA copolymer-doxorubicin conjugates as targeted therapeutics for colorectal cancer

Journal of Drug Targeting

Volumn 19, Issue 10, 2011, Pages 933-943

  Kopansky, Eva ^a   Shamay, Yosi ^a   David, Ayelet ^a  

^a BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

Author keywords

Colorectal cancer; Drug targeting; EGFR; G3 C12; Galectin 3; GE11; HPMA copolymer drug conjugates

Indexed keywords

ALANYLASPARAGINYLTHREONYLPROLYLCYSTEINYLGLYCYLPROLYLTYROSYLTHREONYLHISTIDYLASPARTYLCYSTEINYLPROLYLVALYLLYSYLARGININE; DOXORUBICIN; EPIDERMAL GROWTH FACTOR RECEPTOR; GALACTOSE; GALECTIN 3; N (2 HYDROXYPROPYL)METHACRYLAMIDE COPOLYMER; SYNTHETIC PEPTIDE; TYROSYLHISTIDYLTRYPTOPHYLTYROSYLGLYCYLTYROSYLTHREONYLPROLYLGLUTAMINYLASPARAGINYLVALYLISOLEUCINE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CANCER CELL; CELL FATE; COLORECTAL CANCER; CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG PROTEIN BINDING; DRUG TARGETING; HUMAN; HUMAN CELL; IC 50; IMMUNOFLUORESCENCE TEST; INTERNALIZATION; MACROMOLECULE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYNTHESIS;

ANTIBIOTICS, ANTINEOPLASTIC; CELL LINE, TUMOR; COLORECTAL NEOPLASMS; DOXORUBICIN; DRUG DELIVERY SYSTEMS; GALECTIN 3; HUMANS; LIGANDS; POLYMETHACRYLIC ACIDS; PROTEIN BINDING; RECEPTOR, EPIDERMAL GROWTH FACTOR;

EID: 81255143350     PISSN: 1061186X     EISSN: 10292330     Source Type: Journal    
DOI: 10.3109/1061186X.2011.632011     Document Type: Article

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