Cyclo-oxygenase-2 knockout genotype in mice is associated with blunted angiotensin II-induced oxidative stress and hypertension

American Journal of Hypertension

Volumn 24, Issue 11, 2011, Pages 1239-1244

  Wu, Rong ^a   Duchemin, Sonia ^a   Laplante, Marc André ^a   De Champlain, Jacques ^a   Girouard, Helene ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

angiotensin II; aspirin; blood pressure; cyclo oxygenase free radicals hypertension

Indexed keywords

ACETYLSALICYLIC ACID; ANGIOTENSIN II; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; SUPEROXIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; AORTA; BODY WEIGHT; CELL CULTURE; CELL ISOLATION; CONTROLLED STUDY; GENE DISRUPTION; GENETIC ASSOCIATION; GENOTYPE; HEART; HEART WEIGHT; HYPERTENSION; KNOCKOUT GENE; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; REVIEW; SMOOTH MUSCLE FIBER; SYSTOLIC BLOOD PRESSURE;

ANGIOTENSIN II; ANIMALS; ASPIRIN; BLOOD PRESSURE; CELLS, CULTURED; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; HEART; HYPERTENSION; KIDNEY; MALE; MICE; MICE, KNOCKOUT; MUSCLE, SMOOTH, VASCULAR; ORGAN SIZE; OXIDATIVE STRESS; SUPEROXIDES;

EID: 81155160894     PISSN: 08957061     EISSN: 19417225     Source Type: Journal    
DOI: 10.1038/ajh.2011.137     Document Type: Review

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